Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Kristian Unger"'
Autor:
Mattis Bertlich, Friedrich Ihler, Jennifer L. Spiegel, Kristian Unger, Stefan Küffer, Frank Haubner, Bernhard G. Weiss, Martin Canis, Julia Kitz, Julia Hess, Mahalia Zoe Anczykowski, Mark Jakob
Publikováno v:
Cancer Biomarkers. 33:331-347
BACKGROUND: MicroRNAs constitute promising biomarkers. OBJECTIVE: The aim was to investigate diagnostic and prognostic implications of miR-182-5p and miR-205-5p in p16-positive and p16-negative oropharyngeal squamous cell carcinomas (OPSCCs). METHODS
Autor:
Stefan Kueffer, Bernhard G. Weiss, Friedrich Ihler, Jennifer L. Spiegel, Kristian Unger, Mark Jakob, Lena M. Mattes, Julia Hess, Julia Kitz, Martin Canis, Frank Haubner, Markus D. Schirmer
Publikováno v:
Head & Neck. 43:3707-3719
Background The prognostic impact of hsa-miRNA-182-5p in oral cancer remains unexplored. Therefore, the aim of this study was to investigate the prognostic value of hsa-miRNA-182-5p and its predicted target kinectin 1 (KTN1) in oral squamous cell carc
Autor:
Leon Emanuel Schnöller, Valerie Albrecht, Nikko Brix, Alexander Edward Nieto, Daniel Felix Fleischmann, Maximilian Niyazi, Julia Hess, Claus Belka, Kristian Unger, Kirsten Lauber, Michael Orth
Publikováno v:
Radiat. Oncol. 17:79 (2022)
Background Inherent resistance to radio/chemotherapy is one of the major reasons for early recurrence, treatment failure, and dismal prognosis of glioblastoma. Thus, the identification of resistance driving regulators as prognostic and/or predictive
Autor:
Lisa Kreutzer, Peter Weber, Theresa Heider, Mathias Heikenwälder, Tobias Riedl, Philipp Baumeister, Frederick Klauschen, Claus Belka, Axel Walch, Horst Zitzelsberger, Julia Hess, Kristian Unger
Publikováno v:
Lab. Invest. 102, 1400-1405 (2022)
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) allows spatial analysis of proteins, metabolites, or small molecules from tissue sections. Here, we present the simultaneous generation and analysis of MALDI-MSI, whole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba38a4ed4beb7e8d9caadeef84619fd7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66094
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66094
Autor:
Run Shi, Xin Wang, Yang Wu, Bin Xu, Tianyu Zhao, Christian Trapp, Xuanbin Wang, Kristian Unger, Cheng Zhou, Shun Lu, Alexander Buchner, Gerald Bastian Schulz, Fengjun Cao, Claus Belka, Chuan Su, Minglun Li, Yongqian Shu
Publikováno v:
Theranostics 12, 4181-4199 (2022)
Background: The APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family-mediated mutagenesis is widespread in human cancers. However, our knowledge of the biological feature and clinical relevance of APOBECs and APOBEC mutage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec1e1b2a65251e1aca43504b6155de6
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65454
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65454
Autor:
Mechthild Krause, Jürgen Debus, Henning Schäfer, Bouchra Tawk, Maja Guberina, Sebastian Adeberg, Ingeborg Tinhofer, Karim Zaoui, Martin Stuschke, Steffi Pigorsch, Volker Budach, Julia Hess, Kristian Unger, Thomas Kirchner, Claus Rödel, Esther Herpel, Stephanie E. Combs, Christian Schwager, Amir Abdollahi, Panagiotis Balermpas, Jochen Hess, Anca L. Grosu, Horst Zitzelsberger, Annett Linge, Ute Wirkner, Fabian Lohaus, Melanie Bewerunge-Hudler, Dktk-Rog, Wilko Weichert, P.A. Federspil, Claus Belka, Ute Ganswindt, Katrin Rein, Michael H. Baumann, Philipp Baumeister, Daniel Zips
Publikováno v:
Int. J. Cancer, DOI: 10.1002/ijc.33842 (2021)
Biomarkers with relevance for loco-regional therapy are needed in human papillomavirus negative aka HPV(-) head and neck squamous cell carcinoma (HNSCC). Based on the premise that DNA methylation pattern is highly conserved, we sought to develop a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8abc971113262eef2722448354359d5
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85118946409
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85118946409
Autor:
Peter Weber, Axel Künstner, Julia Hess, Kristian Unger, Sebastian Marschner, Christian Idel, Julika Ribbat-Idel, Philipp Baumeister, Olivier Gires, Christoph Walz, Sibylle Rietzler, Laura Valeanu, Timm Herkommer, Lisa Kreutzer, Olena Klymenko, Guido Drexler, Thomas Kirchner, Cornelius Maihöfer, Ute Ganswindt, Axel Walch, Michael Sterr, Heiko Lickert, Martin Canis, Dirk Rades, Sven Perner, Mauricio Berriel Diaz, Stefan Herzig, Kirsten Lauber, Barbara Wollenberg, Hauke Busch, Claus Belka, Horst Zitzelsberger
Publikováno v:
Clin. Cancer Res. 28, 1038-1052 (2022)
Purpose: The genetic relatedness between primary and recurrent head and neck squamous cell carcinomas (HNSCC) reflects the extent of heterogeneity and therapy-driven selection of tumor subpopulations. Yet, current treatment of recurrent HNSCC ignores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40f7b980fadb86885c12783f8b2d34
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64025
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64025
Autor:
Henrik Schinke, Enxian Shi, Zhongyang Lin, Tanja Quadt, Gisela Kranz, Jiefu Zhou, Hongxia Wang, Julia Hess, Steffen Heuer, Claus Belka, Horst Zitzelsberger, Udo Schumacher, Sandra Genduso, Kristoffer Riecken, Yujing Gao, Zhengquan Wu, Christoph A. Reichel, Christoph Walz, Martin Canis, Kristian Unger, Philipp Baumeister, Min Pan, Olivier Gires
Publikováno v:
Mol. Cancer 21:178 (2022)
Background Epidermal growth factor receptor (EGFR) is both a driver oncogene and a therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC). However, response to EGFR treatment is inconsistent and lacks markers for treatment predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ea6c944678f71d2e9ff705739ff11e
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66150
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66150
Machine learning classifies ferroptosis and apoptosis cell death modalities with TfR1 immunostaining
Publikováno v:
ACS Chem. Biol. 17, 654-660 (2022)
Determining cell death mechanisms occurring in patient and animal tissues is a longstanding goal that requires suitable biomarkers and accurate quantification. However, effective methods remain elusive. To develop more powerful and unbiased analytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef299974a7956c1f0bc6dc878f22d8c
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64532
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64532
Autor:
Elia Lombardo, Julia Hess, Christopher Kurz, Marco Riboldi, Sebastian Marschner, Philipp Baumeister, Kirsten Lauber, Ulrike Pflugradt, Axel Walch, Martin Canis, Frederick Klauschen, Horst Zitzelsberger, Claus Belka, Guillaume Landry, Kristian Unger
Publikováno v:
Eur. J. Cancer 176, 41-49 (2022)
OBJECTIVE: HPV-associated head and neck cancer is correlated with favorable prognosis; however, its underlying biology is not fully understood. We propose an explainable convolutional neural network (CNN) classifier, DeepClassPathway, that predicts H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abf7857f77cb6767be0b8f2d6568eff
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66360
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66360