Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kaneva, R."'
Autor:
Salmon, C, Song, L, Muir, K, UKGPCS Collaborators, Pashayan, N, Dunning, AM, Batra, J, APCB BioResource (Australian Prostate Cancer BioResource), Chambers, S, Stanford, JL, Ostrander, EA, Park, JY, Lin, H-Y, Cussenot, O, Cancel-Tassin, G, Menegaux, F, Cordina-Duverger, E, Kogevinas, M, Llorca, J, Kaneva, R, Slavov, C, Razack, A, Lim, J, Gago-Dominguez, M, Castelao, JE, Kote-Jarai, Z, Eeles, RA, on behalf of the PRACTICAL Consortium, Parent, M-É
While being in a committed relationship is associated with a better prostate cancer prognosis, little is known about how marital status relates to its incidence. Social support provided by marriage/relationship could promote a healthy lifestyle and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::dc37a08650fdc52350cd212582632898
https://hdl.handle.net/10453/152661
https://hdl.handle.net/10453/152661
Autor:
Justice, CM, Musolf, AM, Cuellar, A, Lattanzi, W, Simeonov, E, Kaneva, R, Paschall, J, Cunningham, M, Wilkie, AOM, Wilson, AF, Romitti, PA, Boyadjiev, SA
Publikováno v:
Genes; Volume 13; Issue 5; Pages: 816
Craniosynostosis (CS) is a major birth defect in which one or more skull sutures fuse prematurely. We previously performed a genome-wide association study (GWAS) for sagittal non-syndromic CS (sNCS), identifying associations downstream from BMP2 on 2
Autor:
Matejcic, M, Saunders, EJ, Dadaev, T, Brook, MN, Wang, K, Sheng, X, Olama, AAA, Schumacher, FR, Ingles, SA, Govindasami, K, Benlloch, S, Berndt, SI, Albanes, D, Koutros, S, Muir, K, Stevens, VL, Gapstur, SM, Tangen, CM, Batra, J, Clements, J, Gronberg, H, Pashayan, N, Schleutker, J, Wolk, A, West, C, Mucci, L, Kraft, P, Cancel-Tassin, G, Sorensen, KD, Maehle, L, Grindedal, EM, Strom, SS, Neal, DE, Hamdy, FC, Donovan, JL, Travis, RC, Hamilton, RJ, Rosenstein, B, Lu, YJ, Giles, GG, Kibel, AS, Vega, A, Bensen, JT, Kogevinas, M, Penney, KL, Park, JY, Stanford, JL, Cybulski, C, Nordestgaard, BG, Brenner, H, Maier, C, Kim, J, Teixeira, MR, Neuhausen, SL, De Ruyck, K, Razack, A, Newcomb, LF, Lessel, D, Kaneva, R, Usmani, N, Claessens, F, Townsend, PA, Dominguez, MG, Roobol, MJ, Menegaux, F, Khaw, KT, Cannon-Albright, LA, Pandha, H, Thibodeau, SN, Schaid, DJ, Henderson, BE, Stern, MC, Thwaites, A, Guy, M, Whitmore, I, Morgan, A, Fisher, C, Hazel, S, Livni, N, Cook, M, Fachal, L, Weinstein, S, Beane Freeman, LE, Hoover, RN, Machiela, MJ, Lophatananon, A, Carter, BD, Goodman, P, Moya, L, Srinivasan, S, Kedda, MA, Yeadon, T, Eckert, A, Eklund, M, Cavalli-Bjoerkman, C, Dunning, AM, Sipeky, C, Hakansson, N, Elliott, R, Ranu, H
© 2018, The Author(s). Chromosome 8q24 is a susceptibility locus for multiple cancers, including prostate cancer. Here we combine genetic data across the 8q24 susceptibility region from 71,535 prostate cancer cases and 52,935 controls of European an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::500f22c7a6fd65f907aa5d5093d95e6b
https://hdl.handle.net/10453/132491
https://hdl.handle.net/10453/132491
Autor:
Bull, CJ, Bonilla, C, Holly, JM, Perks, CM, Davies, N, Haycock, P, Yu, OH, Richards, JB, Eeles, R, Easton, D, Kote-Jarai, Z, Amin Al Olama, A, Benlloch, S, Muir, K, Giles, GG, MacInnis, RJ, Wiklund, F, Gronberg, H, Haiman, CA, Schleutker, J, Nordestgaard, BG, Travis, RC, Neal, D, Pashayan, N, Khaw, KT, Stanford, JL, Blot, WJ, Thibodeau, S, Maier, C, Kibel, AS, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Teixeira, MR, Micheal, A, Pandha, H, Smith, GD, Lewis, SJ, Martin, RM
Publikováno v:
Cancer Medicine
Bull, C J, Bonilla, C, Holly, J M P, Perks, C M, Davies, N, Haycock, P, Yu, O H Y, Richards, J B, Eeles, R, Easton, D, Kote-Jarai, Z, Amin Al Olama, A, Benlloch, S, Muir, K, Giles, G G, MacInnis, R J, Wiklund, F, Gronberg, H, Haiman, C A, Schleutker, J, Nordestgaard, B G, Travis, R C, Neal, D, Pashayan, N, Khaw, K-T, Stanford, J L, Blot, W J, Thibodeau, S, Maier, C, Kibel, A S, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Teixeira, M R, Micheal, A, Pandha, H, Smith, G D, Lewis, S J, Martin, R M & the PRACTICAL Consortium 2016, ' Blood lipids and prostate cancer : a Mendelian randomization analysis ', Cancer Medicine, vol. 5, no. 6, pp. 1125-1136 . https://doi.org/10.1002/cam4.695
Bull, C J, Bonilla, C, Holly, J M P, Perks, C M, Davies, N, Haycock, P, Yu, O H Y, Richards, J B, Eeles, R, Easton, D, Kote-Jarai, Z, Amin Al Olama, A, Benlloch, S, Muir, K, Giles, G G, MacInnis, R J, Wiklund, F, Gronberg, H, Haiman, C A, Schleutker, J, Nordestgaard, B G, Travis, R C, Neal, D, Pashayan, N, Khaw, K-T, Stanford, J L, Blot, W J, Thibodeau, S, Maier, C, Kibel, A S, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Teixeira, M R, Micheal, A, Pandha, H, Smith, G D, Lewis, S J, Martin, R M & the PRACTICAL Consortium 2016, ' Blood lipids and prostate cancer : a Mendelian randomization analysis ', Cancer Medicine, vol. 5, no. 6, pp. 1125-1136 . https://doi.org/10.1002/cam4.695
Genetic risk scores were used as unconfounded instruments for specific lipid traits (Mendelian randomization) to assess whether circulating lipids causally influence prostate cancer risk. Data from 22,249 prostate cancer cases and 22,133 controls fro
Autor:
Dadaev, T, Saunders, EJ, Newcombe, PJ, Anokian, E, Leongamornlert, DA, Brook, MN, Cieza-Borrella, C, Mijuskovic, M, Wakerell, S, Olama, AAA, Schumacher, FR, Berndt, SI, Benlloch, S, Ahmed, M, Goh, C, Sheng, X, Zhang, Z, Muir, K, Govindasami, K, Lophatananon, A, Stevens, VL, Gapstur, SM, Carter, BD, Tangen, CM, Goodman, P, Thompson, IM, Batra, J, Chambers, S, Moya, L, Clements, J, Horvath, L, Tilley, W, Risbridger, G, Gronberg, H, Aly, M, Nordström, T, Pharoah, P, Pashayan, N, Schleutker, J, Tammela, TLJ, Sipeky, C, Auvinen, A, Albanes, D, Weinstein, S, Wolk, A, Hakansson, N, West, C, Dunning, AM, Burnet, N, Mucci, L, Giovannucci, E, Andriole, G, Cussenot, O, Cancel-Tassin, G, Koutros, S, Freeman, LEB, Sorensen, KD, Orntoft, TF, Borre, M, Maehle, L, Grindedal, EM, Neal, DE, Donovan, JL, Hamdy, FC, Martin, RM, Travis, RC, Key, TJ, Hamilton, RJ, Fleshner, NE, Finelli, A, Ingles, SA, Stern, MC, Rosenstein, B, Kerns, S, Ostrer, H, Lu, Y-J, Zhang, H-W, Feng, N, Mao, X, Guo, X, Wang, G, Sun, Z, Giles, GG, Southey, MC, Macinnis, RJ, Fitzgerald, LM, Kibel, AS, Drake, BF, Vega, A, Gómez-Caamaño, A, Fachal, L, Szulkin, R, Eklund, M, Kogevinas, M, Llorca, J, Castaño-Vinyals, G, Penney, KL, Stampfer, M, Park, JY, Sellers, TA, Lin, H-Y, Stanford, JL, Cybulski, C, Wokolorczyk, D, Lubinski, J, Ostrander, EA, Geybels, MS, Nordestgaard, BG, Nielsen, SF, Weisher, M, Bisbjerg, R, Røder, MA, Iversen, P, Brenner, H, Cuk, K, Holleczek, B, Maier, C, Luedeke, M, Schnoeller, T, Kim, J, Logothetis, CJ, John, EM, Teixeira, MR, Paulo, P, Cardoso, M, Neuhausen, SL, Steele, L, Ding, YC, De Ruyck, K, De Meerleer, G, Ost, P, Razack, A, Lim, J, Teo, S-H, Lin, DW, Newcomb, LF, Lessel, D, Gamulin, M, Kulis, T, Kaneva, R, Usmani, N, Slavov, C, Mitev, V, Parliament, M, Singhal, S, Claessens, F, Joniau, S, Van Den Broeck, T, Larkin, S, Townsend, PA, Aukim-Hastie, C, Gago-Dominguez, M, Castelao, JE, Martinez, ME, Roobol, MJ, Jenster, G, Van Schaik, RHN, Menegaux, F, Truong, T, Koudou, YA, Xu, J, Khaw, K-T, Cannon-Albright, L, Pandha, H, Michael, A, Kierzek, A, Thibodeau, SN, McDonnell, SK, Schaid, DJ, Lindstrom, S, Turman, C, Ma, J, Hunter, DJ, Riboli, E, Siddiq, A, Canzian, F, Kolonel, LN, Le Marchand, L, Hoover, RN, Machiela, MJ, Kraft, P, Consortium, Practical (Prostate Cancer Association Group To Investigate Cancer-Associated Alterations In The Genome), Freedman, M, Wiklund, F, Chanock, S, Henderson, BE, Easton, DF, Haiman, CA, Eeles, RA, Conti, DV, Kote-Jarai, Z
Publikováno v:
Nature Communications, 9:2256. Nature Publishing Group
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
NATURE COMMUNICATIONS
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0bf073e818a65d824db9940163b4958c
https://www.repository.cam.ac.uk/handle/1810/278592
https://www.repository.cam.ac.uk/handle/1810/278592
Autor:
Zuber, V., Bettella, F., Witoelar, A.W., Andreassen, O.A., Mills, I.G., Urbanucci, A., Eeles, R.A., Easton, D.F., Kote-Jarai, Z., Al Olama, A.A., Benlloch, S., Muir, K., Giles, G.G., Wiklund, F., Grönberg, H., Haiman, C.A., Schleutker, J., Weischer, M., Travis, R.C., Neal, D., Pharoah, P., Khaw, K.T., Stanford, J.L., Blot, W.J., Thibodeau, S.N., Maier, C., Kibel, A.S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M.R., Pandha, H., Chenevix-Trench, G., Humphreys, M.K., Hung, R.J., Han, Y., Brennan, P., Bickeböller, H., Rosenberger, A., Houlston, R.S., Caporaso, N., Landi, M.T., Heinrich, J., Risch, A., Wu, X., Ye, Y., Christiani, D.C., Amos, C.I., Michailidou, K., Bolla, M.K., Wang, Q., Berchuck, A., Antoniou, A.C., McGuffog, L., Couch, F.J., Offit, K., Dennis, J., Dunning, A.M., Lee, A., Dicks, E., Luccarini, C., Benítez, J., González-Neira, A., Simard, J., Tessier, D.C., Bacot, F., Vincent, D., Laboissiere, S.
Publikováno v:
Zuber, V, Bettella, F, Witoelar, A, Andreassen, O A, Mills, I G, Urbanucci, A & PRACTICAL Consortium 2017, ' Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer ', BMC Genomics, vol. 18, no. 1, pp. 270 . https://doi.org/10.1186/s12864-017-3620-y
BMC Genomics 18:270 (2017)
BMC Genomics
BMC Genomics 18:270 (2017)
BMC Genomics
Background Epigenetic information can be used to identify clinically relevant genomic variants single nucleotide polymorphisms (SNPs) of functional importance in cancer development. Super-enhancers are cell-specific DNA elements, acting to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::133f15c80a2e8e02e0caa94528d115e8
https://doi.org/10.1186/s12864-017-3620-y
https://doi.org/10.1186/s12864-017-3620-y
Autor:
Bonilla, C, Lewis, SJ, Rowlands, MA, Gaunt, TR, Davey Smith, G, Gunnell, D, Palmer, T, Donovan, JL, Hamdy, F, Neal, DE, Eeles, R, Easton, D, Kote-Jarai, Z, Al Olama, AA, Benlloch, S, Muir, K, Giles, GG, Wiklund, F, Grönberg, H, Haiman, CA, Schleutker, J, Nordestgaard, BG, Travis, RC, Pashayan, N, Khaw, KT, Stanford, JL, Blot, WJ, Thibodeau, S, Maier, C, Kibel, AS, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Teixeira, MR, Pandha, H, Lathrop, M, Martin, RM, Holly, JM
Publikováno v:
Bonilla, C, Lewis, S J, Rowlands, M-A, Gaunt, T R, Davey-Smith, G, Gunnell, D, Palmer, T M, Donovan, J L, Hamdy, F C, Neal, D E, Eeles, R, Easton, D, Kote-Jarai, Z, Al Olama, A A, Benlloch, S, Muir, K, Giles, G, Wiklund, F, Grönberg, H, Haiman, C A, Schleutker, J, Nordestgaard, B G, Travis, R C, Pashayan, N, Khaw, K-T, Stanford, J L, Blot, W J, Thibodeau, S N, Maier, C, Kibel, A S, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J-S, Kaneva, R, Batra, J, Teixeira, M R, Pandha, H, PRACTICAL consortium, Lathrop, M, Martin, R M & Holly, J M P 2016, ' Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization : Genetic variants as instruments for circulating levels ', International Journal of Cancer, vol. 139, no. 7, pp. 1520-1533 . https://doi.org/10.1002/ijc.30206
International Journal of Cancer
Bonilla, C, Lewis, S J, Rowlands, M A, Gaunt, T R, Davey Smith, G, Gunnell, D, Palmer, T, Donovan, J L, Hamdy, F C, Neal, D E, Eeles, R, Easton, D, Kote-Jarai, Z, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Wiklund, F, Grönberg, H, Haiman, C A, Schleutker, J, Nordestgaard, B G, Travis, R C, Pashayan, N, Khaw, K T, Stanford, J L, Blot, W J, Thibodeau, S, Maier, C, Kibel, A S, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Teixeira, M R, Pandha, H, Lathrop, M, Martin, R M & Holly, J M P 2016, ' Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization : Genetic variants as instruments for circulating levels ', International Journal of Cancer, vol. 139, no. 7, pp. 1520-1533 . https://doi.org/10.1002/ijc.30206
International Journal of Cancer
Bonilla, C, Lewis, S J, Rowlands, M A, Gaunt, T R, Davey Smith, G, Gunnell, D, Palmer, T, Donovan, J L, Hamdy, F C, Neal, D E, Eeles, R, Easton, D, Kote-Jarai, Z, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Wiklund, F, Grönberg, H, Haiman, C A, Schleutker, J, Nordestgaard, B G, Travis, R C, Pashayan, N, Khaw, K T, Stanford, J L, Blot, W J, Thibodeau, S, Maier, C, Kibel, A S, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Teixeira, M R, Pandha, H, Lathrop, M, Martin, R M & Holly, J M P 2016, ' Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization : Genetic variants as instruments for circulating levels ', International Journal of Cancer, vol. 139, no. 7, pp. 1520-1533 . https://doi.org/10.1002/ijc.30206
Circulating insulin‐like growth factors (IGFs) and their binding proteins (IGFBPs) are associated with prostate cancer. Using genetic variants as instruments for IGF peptides, we investigated whether these associations are likely to be causal. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ded14e251c77db66ff55de5df12e8516
https://curis.ku.dk/portal/da/publications/assessing-the-role-of-insulinlike-growth-factors-and-binding-proteins-in-prostate-cancer-using-mendelian-randomization(3f47b3eb-5ece-4e3e-b0ed-85df423eca92).html
https://curis.ku.dk/portal/da/publications/assessing-the-role-of-insulinlike-growth-factors-and-binding-proteins-in-prostate-cancer-using-mendelian-randomization(3f47b3eb-5ece-4e3e-b0ed-85df423eca92).html
Autor:
Møller, R.S., Weber, Y.G., Klitten, L.L., Trucks, H., Muhle, H., Kunz, W.S., Mefford, H.C., Franke, A., Kautza, M., Wolf, P., Dennig, D., Schreiber, S., Rückert, I.M., Wichmann, H.E., Ernst, J.P., Schurmann, C., Grabe, H.J., Tommerup, N., Stephani, U., Lerche, H., Hjalgrim, H., Helbig, I., Sander, T., Zimprich, F., Mörzinger, M., Feucht, M., Suls, A., Weckhuysen, S., Claes, L., Deprez, L., Smets, K., Van Dyck, T., Deconinck, T., De Jonghe, P., Velizarova, R., Dimova, P., Radionova, M., Tournev, I., Kancheva, D., Kaneva, R., Jordanova, A., Kjelgaard, D.B., Lehesjoki, A.E., Siren, A., Baulac, S., Leguern, E., Von Spiczak, S., Ostertag, P., Leber, M., Leu, C., Toliat, M.R., Nürnberg, P., Hempelmann, A., Rüschendorf, F., Elger, C.E., Kleefuß Lie, A.A., Surges, R., Gaus, V., Janz, D., Schmitz, B., Klein, K.M., Reif, P.S., Oertel, W.H., Hamer, H.M., Rosenow, F., Becker, F., Marini, C., Guerrini, R., Mei, D., Norci, V., Zara, F., Striano, P., Robbiano, A., Pezzella, M., Bianchi, A., Gambardella, A., Tinuper, P., La Neve, A., Capovilla, G., Vigliano, P., Crichiutti, G., Vanadia, F., Vignoli, A., Coppola, A., Striano, S., Giallonardo, M.T., Franceschetti, S., Belcastro, V., Benna, P., Coppola, G., De Palo, A., Ferlazzo, E., Vecchi, M., Martinelli, V., Bisulli, F., Beccaria, F., Del Giudice, E., Mancardi, M., Stranci, G., Scabar, A., Gobbi, G., Giordano, I., Koeleman, B.P.C., De Kovel, C., Lindhout, D., De Haan, G.J., Ozbeck, U., Bebek, N., Baykan, B., Ozdemir, O., Ugur, S., Kocasoy Orhan, E., Yücesan, E., Cine, N., Gokyigit, A., Gurses, C., Gul, G., Yapici, Z., Ozkara, C., Caglayan, H., Yalcin, O., Yalcin, D., Turkdogan, D., Dizdarer, G., Agan, K.
Publikováno v:
Epilepsia
Møller, R S, YG, W, Klitten, L L, H, T, H, M, WS, K, HC, M, A, F, M, K, P, W, D, D, S, S, IM, R, HE, W, JP, E, C, S, HJ, G, N, T, U, S, H, L, Hjalgrim, H, I, H & T, S 2013, ' Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy ', Epilepsia, vol. 54, no. 2, pp. 256-264 . https://doi.org/10.1111/epi.12078
Epilepsia 54, 256-264 (2013)
Møller, R S, YG, W, Klitten, L L, H, T, H, M, WS, K, HC, M, A, F, M, K, P, W, D, D, S, S, IM, R, HE, W, JP, E, C, S, HJ, G, N, T, U, S, H, L, Hjalgrim, H, I, H & T, S 2013, ' Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy ', Epilepsia, vol. 54, no. 2, pp. 256-264 . https://doi.org/10.1111/epi.12078
Epilepsia 54, 256-264 (2013)
Summary Purpose Neurexins are neuronal adhesion molecules located in the presynaptic terminal, where they interact with postsynaptic neuroligins to form a transsynaptic complex required for efficient neurotransmission in the brain. Recently, deletion
Autor:
Saunders, EJ, Dadaev, T, Leongamornlert, DA, Olama, AA, Benlloch, S, Giles, GG, Wiklund, F, Grönberg, H, Haiman, CA, Schleutker, J, Nordestgaard, BG, Travis, RC, Neal, D, Pasayan, N, Khaw, KT, Stanford, JL, Blot, WJ, Thibodeau, SN, Maier, C, Kibel, AS, Cybulski, C, Cannon-Albright, L, Brenner, H, Park, JY, Kaneva, R, Batra, J, Teixeira, MR, Pandha, H, Govindasami, K, Muir, K, Genetic Prostate Cancer Study Collaborators, UK, ProtecT Study Collaborators, UK, Consortium, PRACTICAL, Easton, DF, Eeles, RA, Kote-Jarai, Z
BACKGROUND: Germline mutations within DNA-repair genes are implicated in susceptibility to multiple forms of cancer. For prostate cancer (PrCa), rare mutations in BRCA2 and BRCA1 give rise to moderately elevated risk, whereas two of ∼100 common, lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::88c60b9a74f2d10a40f116c3dd3a86bc
https://www.repository.cam.ac.uk/handle/1810/255991
https://www.repository.cam.ac.uk/handle/1810/255991
Autor:
Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, HW, Ingles, SA, Kittles, RA, Strom, SS, Rybicki, BA, Nemesure, B, Isaacs, WB, Zheng, W, Pettaway, CA, Yeboah, ED, Tettey, Y, Biritwum, RB, Adjei, AA, Tay, E, Truelove, A, Niwa, S, Chokkalingam, AP, John, EM, Murphy, AB, Signorello, LB, Carpten, J, Leske, MC, Wu, S-Y, Hennis, AJM, Neslund-Dudas, C, Hsing, AW, Chu, L, Goodman, PJ, Klein, EA, Witte, JS, Casey, G, Kaggwa, S, Cook, MB, Stram, DO, Blot, WJ, Eeles, RA, Easton, D, Kote-Jarai, Z, Al Olama, AA, Benlloch, S, Muir, K, Giles, GG, Southey, MC, Fitzgerald, LM, Gronberg, H, Wiklund, F, Aly, M, Henderson, BE, Schleutker, J, Wahlfors, T, Tammela, TLJ, Nordestgaard, BG, Key, TJ, Travis, RC, Neal, DE, Donovan, JL, Hamdy, FC, Pharoah, P, Pashayan, N, Khaw, K-T, Stanford, JL, Thibodeau, SN, McDonnell, SK, Schaid, DJ, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, AS, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Teerlink, C, Brenner, H, Dieffenbach, AK, Arndt, V, Park, JY, Sellers, TA, Lin, H-Y, Slavov, C, Kaneva, R, Mitev, V, Batra, J, Spurdle, A, Clements, JA, Teixeira, MR, Pandha, HS, Michael, A, Paulo, P, Maia, S, Kierzek, A, Conti, DV, Albanes, D, Berg, C, Berndt, SI, Campa, D, Crawford, ED, Diver, WR, Gapstur, SM, Gaziano, JM, Giovannucci, E, Hoover, R, Hunter, DJ, Johansson, M, Kraft, P, Le Marchand, L, Lindstrom, S, Navarro, C, Overvad, K, Riboli, E, Siddiq, A, Stevens, VL, Trichopoulos, D, Vineis, P, Yeager, M, Trynka, G, Raychaudhuri, S, Schumacher, FR, Price, AL, Freedman, ML, Haiman, CA, Pasaniuc, B, Cook, M, Guy, M, Govindasami, K, Leongamornlert, D, Sawyer, EJ, Wilkinson, R, Saunders, EJ, Tymrakiewicz, M, Dadaev, T, Morgan, A, Fischer, C, Hazel, S, Livni, N, Lophatananon, A, Pedersen, J, Hopper, JL, Adolfson, J, Stattin, P, Johansson, J-E, Cavalli-Bjoerkman, C, Karlsson, A, Broms, M, Auvinen, A, Kujala, P, Maeaettaenen, L, Murtola, T, Taari, K, Weischer, M, Nielsen, SF, Klarskov, P, Roder, A, Iversen, P, Wallinder, H, Tillmans, L, Riska, S, Wang, L, Rinckleb, A, Lubiski, J, Stegmaier, C, Pow-Sang, J, Park, H, Radlein, S, Rincon, M, Haley, J, Zachariah, B, Kachakova, D, Popov, E, Mitkova, A, Vlahova, A, Dikov, T, Christova, S, Heathcote, P, Wood, G, Malone, G, Saunders, K, Eckert, A, Yeadon, T, Kerr, K, Collins, A, Turner, M, Srinivasan, S, Kedda, M-A, Alexander, K, Omara, T, Wu, H, Henrique, R, Pinto, P, Santos, J, Barros-Silva, J
Publikováno v:
Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, H W, Ingles, S A, Kittles, R A, Strom, S S, Rybicki, B A, Nemesure, B, Isaacs, W B, Zheng, W, Pettaway, C A, Yeboah, E D, Tettey, Y, Biritwum, R B, Adjei, A A, Tay, E, Truelove, A, Niwa, S, Chokkalingam, A P, John, E M, Murphy, A B, Signorello, L B, Carpten, J, Leske, M C, Wu, S-Y, Hennis, A J M, Neslund-Dudas, C, Hsing, A W, Chu, L, Goodman, P J, Klein, E A, Witte, J S, Casey, G, Kaggwa, S, Cook, M B, Stram, D O, Blot, W J, Eeles, R A, Easton, D, Kote-Jarai, ZS, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Southey, M C, Fitzgerald, L M, Overvad, K & PRACTICAL consortium 2016, ' Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation ', Nature Communications, vol. 7, pp. 10979 . https://doi.org/10.1038/ncomms10979
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, H W, Ingles, S A, Kittles, R A, Strom, S S, Rybicki, B A, Nemesure, B, Isaacs, W B, Zheng, W, Pettaway, C A, Yeboah, E D, Tettey, Y, Biritwum, R B, Adjei, A A, Tay, E, Truelove, A, Niwa, S, Chokkalingam, A P, John, E M, Murphy, A B, Signorello, L B, Carpten, J, Leske, M C, Wu, S-Y, Hennis, A J M, Neslund-Dudas, C, Hsing, A W, Chu, L, Goodman, P J, Klein, E A, Witte, J S, Casey, G, Kaggwa, S, Cook, M B, Stram, D O, Blot, W J, Eeles, R A, Easton, D, Kote-Jarai, ZS, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Southey, M C, Fitzgerald, L M, Raychaudhuri, S & PRACTICAL Consortium 2016, ' Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation ', Nature Communications, vol. 7, 10979 . https://doi.org/10.1038/ncomms10979
Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, H W, Ingles, S A, Kittles, R A, Strom, S S, Rybicki, B A, Nemesure, B, Isaacs, W B, Zheng, W, Pettaway, C A, Yeboah, E D, Tettey, Y, Biritwum, R B, Adjei, A A, Tay, E, Truelove, A, Niwa, S, Chokkalingam, A P, John, E M, Murphy, A B, Signorello, L B, Carpten, J, Leske, M C, Wu, S Y, Hennis, A J M, Neslund-Dudas, C, Hsing, A W, Chu, L, Goodman, P J, Klein, E A, Witte, J S, Casey, G, Kaggwa, S, Cook, M B, Stram, D O, Blot, W J, Eeles, R A, Easton, D, Kote-Jarai, Z, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Southey, M C, Fitzgerald, L M, Gronberg, H, Wiklund, F, Aly, M, Henderson, B E, Schleutker, J, Wahlfors, T, Tammela, T L J, Nordestgaard, B G, Key, T J, Travis, R C, Neal, D E, Donovan, J L, Hamdy, F C, Pharoah, P, Pashayan, N, Khaw, K T, Stanford, J L, Thibodeau, S N, McDonnell, S K, Schaid, D J, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, A S, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Teerlink, C, Brenner, H, Dieffenbach, A K, Arndt, V, Park, J Y, Sellers, T A, Lin, H Y, Slavov, C, Kaneva, R, Mitev, V, Batra, J, Spurdle, A, Clements, J A, Teixeira, M R, Pandha, H, Michael, A, Paulo, P, Maia, S, Kierzek, A, Conti, D V, Albanes, D, Berg, C, Berndt, S I, Campa, D, Crawford, E D, Diver, W R, Gapstur, S M, Gaziano, J M, Giovannucci, E, Hoover, R, Hunter, D J, Johansson, M, Kraft, P, Le Marchand, L, Lindström, S, Navarro, C, Overvad, K, Riboli, E, Siddiq, A, Stevens, V L, Trichopoulos, D, Vineis, P, Yeager, M, Trynka, G, Raychaudhuri, S, Schumacher, F R, Price, A L, Freedman, M L, Haiman, C A & Pasaniuc, B 2016, ' Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation ', Nature Communications, vol. 7, 10979 . https://doi.org/10.1038/ncomms10979
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, H W, Ingles, S A, Kittles, R A, Strom, S S, Rybicki, B A, Nemesure, B, Isaacs, W B, Zheng, W, Pettaway, C A, Yeboah, E D, Tettey, Y, Biritwum, R B, Adjei, A A, Tay, E, Truelove, A, Niwa, S, Chokkalingam, A P, John, E M, Murphy, A B, Signorello, L B, Carpten, J, Leske, M C, Wu, S-Y, Hennis, A J M, Neslund-Dudas, C, Hsing, A W, Chu, L, Goodman, P J, Klein, E A, Witte, J S, Casey, G, Kaggwa, S, Cook, M B, Stram, D O, Blot, W J, Eeles, R A, Easton, D, Kote-Jarai, ZS, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Southey, M C, Fitzgerald, L M, Raychaudhuri, S & PRACTICAL Consortium 2016, ' Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation ', Nature Communications, vol. 7, 10979 . https://doi.org/10.1038/ncomms10979
Gusev, A, Shi, H, Kichaev, G, Pomerantz, M, Li, F, Long, H W, Ingles, S A, Kittles, R A, Strom, S S, Rybicki, B A, Nemesure, B, Isaacs, W B, Zheng, W, Pettaway, C A, Yeboah, E D, Tettey, Y, Biritwum, R B, Adjei, A A, Tay, E, Truelove, A, Niwa, S, Chokkalingam, A P, John, E M, Murphy, A B, Signorello, L B, Carpten, J, Leske, M C, Wu, S Y, Hennis, A J M, Neslund-Dudas, C, Hsing, A W, Chu, L, Goodman, P J, Klein, E A, Witte, J S, Casey, G, Kaggwa, S, Cook, M B, Stram, D O, Blot, W J, Eeles, R A, Easton, D, Kote-Jarai, Z, Al Olama, A A, Benlloch, S, Muir, K, Giles, G G, Southey, M C, Fitzgerald, L M, Gronberg, H, Wiklund, F, Aly, M, Henderson, B E, Schleutker, J, Wahlfors, T, Tammela, T L J, Nordestgaard, B G, Key, T J, Travis, R C, Neal, D E, Donovan, J L, Hamdy, F C, Pharoah, P, Pashayan, N, Khaw, K T, Stanford, J L, Thibodeau, S N, McDonnell, S K, Schaid, D J, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, A S, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Teerlink, C, Brenner, H, Dieffenbach, A K, Arndt, V, Park, J Y, Sellers, T A, Lin, H Y, Slavov, C, Kaneva, R, Mitev, V, Batra, J, Spurdle, A, Clements, J A, Teixeira, M R, Pandha, H, Michael, A, Paulo, P, Maia, S, Kierzek, A, Conti, D V, Albanes, D, Berg, C, Berndt, S I, Campa, D, Crawford, E D, Diver, W R, Gapstur, S M, Gaziano, J M, Giovannucci, E, Hoover, R, Hunter, D J, Johansson, M, Kraft, P, Le Marchand, L, Lindström, S, Navarro, C, Overvad, K, Riboli, E, Siddiq, A, Stevens, V L, Trichopoulos, D, Vineis, P, Yeager, M, Trynka, G, Raychaudhuri, S, Schumacher, F R, Price, A L, Freedman, M L, Haiman, C A & Pasaniuc, B 2016, ' Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation ', Nature Communications, vol. 7, 10979 . https://doi.org/10.1038/ncomms10979
Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of Europea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d19c292435b64970087e6ff6ee9690
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-122103
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-122103