Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Jones, David"'
Autor:
Langenberg, Karin P.S., Meister, Michael T., Bakhuizen, Jette J., Boer, Judith M., van Eijkelenburg, Natasha K.A., Hulleman, Esther, Ilan, Uri, Looze, Eleonora J., Dierselhuis, Miranda P., van der Lugt, Jasper, Breunis, Willemijn, Schild, Linda G., Ober, Kimberley, van Hooff, Sander R., Scheijde-Vermeulen, Marijn A., Hiemcke-Jiwa, Laura S., Flucke, Uta E., Kranendonk, Mariette E.G., Wesseling, Pieter, Sonneveld, Edwin, Punt, Simone, Boltjes, Arjan, van Dijk, Freerk, Verwiel, Eugene T.P., Volckmann, Richard, Hehir-Kwa, Jayne Y., Kester, Lennart A., Koudijs, Marco M.J., Waanders, Esme, Holstege, Frank C.P., Vormoor, H. Josef, Hoving, Eelco W., van Noesel, Max M., Pieters, Rob, Kool, Marcel, Stumpf, Miriam, Blattner-Johnson, Mirjam, Balasubramanian, Gnana P., Van Tilburg, Cornelis M., Jones, Barbara C., Jones, David T.W., Witt, Olaf, Pfister, Stefan M., Jongmans, Marjolijn C.J., Kuiper, Roland P., de Krijger, Ronald R., Wijnen, Marc H.W., den Boer, Monique L., Zwaan, C. Michel, Kemmeren, Patrick, Koster, Jan, Tops, Bastiaan B.J., Goemans, Bianca F., Molenaar, Jan J., Dep Scheikunde, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
European Journal of Cancer, 175, 311. Elsevier Ltd
European Journal of Cancer, 175, 311-325. Elsevier Limited
European Journal of Cancer, 175, 311-325. Elsevier Limited
iTHER is a Dutch prospective national precision oncology program aiming to define tumour molecular profiles in children and adolescents with primary very high-risk, relapsed, or refractory paediatric tumours. Between April 2017 and April 2021, 302 sa
Autor:
Staffaroni, Adam M, Quintana, Melanie, Heller, Carolin, Boeve, Bradley F, Rosen, Howard J, Rohrer, Jonathan D, Boxer, Adam L, Initiative, Frontotemporal Dementia Prevention, Apostolova, Liana, Barmada, Sami, Boeve, Bradley, Bozoki, Andrea, Clark, Annie L, Clark, David, Coppola, Giovanni, Darby, Ryan, Dickson, Dennis, Faber, Kelley, Fagan, Anne, Galasko, Douglas R, Grant, Ian M, Huang, Eric, Kerwin, Diana, Taylor, Jack Carson, Lapid, Maria, Lee, Suzee, Leger, Gabriel, Masdeux, Joseph C, McGinnis, Scott, Mendez, Mario, Onyike, Chiadi, Pascual, M Belen, Pressman, Peter, Rademakers, Rosa, Wise, Amy, Ramanan, Vijay, Ritter, Aaron, Seeley, William W, Syrjanen, Jeremy, Taylor, Jack C, Weintraub, Sandra, Esteve, Aitana Sogorb, Nelson, Annabel, Greaves, Caroline V, Thomas, David L, Ong, Elise, Benotmane, Hanya, Zetterberg, Henrik, Nicholas, Jennifer, Samra, Kiran, Shafei, Rachelle, Timberlake, Carolyn, Cope, Thomas, Rittman, Timothy, Benussi, Alberto, Premi, Enrico, Forsberg, Leah, Gasparotti, Roberto, Archetti, Silvana, Gazzina, Stefano, Cantoni, Valentina, Arighi, Andrea, Fenoglio, Chiara, Scarpini, Elio, Fumagalli, Giorgio, Borracci, Vittoria, Rossi, Giacomina, Brushaber, Danielle, Giaccone, Giorgio, Di Fede, Giuseppe, Caroppo, Paola, Prioni, Sara, Redaelli, Veronica, Tang-Wai, David, Rogaeva, Ekaterina, Castelo-Branco, Miguel, Freedman, Morris, Keren, Ron, Rojas, Julio C, Black, Sandra, Mitchell, Sara, Shoesmith, Christen, Bartha, Robart, Poos, Jackie, Papma, Janne M, Giannini, Lucia, van Minkelen, Rick, Pijnenburg, Yolande, Nacmias, Benedetta, VandeVrede, Lawren, Ferrari, Camilla, Polito, Cristina, Lombardi, Gemma, Bessi, Valentina, Veldsman, Michele, Andersson, Christin, Thonberg, Hakan, Öijerstedt, Linn, Jelic, Vesna, Thompson, Paul, Ljubenkov, Peter, Lladó, Albert, Antonell, Anna, Olives, Jaume, Balasa, Mircea, Bargalló, Nuria, Borrego-Ecija, Sergi, Verdelho, Ana, Maruta, Carolina, Ferreira, Catarina B, Miltenberger, Gabriel, Wendelberger, Barbara, Kramer, Joel, Simões do Couto, Frederico, Gabilondo, Alazne, Gorostidi, Ana, Villanua, Jorge, Cañada, Marta, Tainta, Mikel, Zulaica, Miren, Barandiaran, Myriam, Alves, Patricia, Bender, Benjamin, Casaletto, Kaitlin B, Wilke, Carlo, Graf, Lisa, Vogels, Annick, Vandenbulcke, Mathieu, Van Damme, Philip, Bruffaerts, Rose, Poesen, Koen, Rosa-Neto, Pedro, Gauthier, Serge, Camuzat, Agnès, Appleby, Brian, Brice, Alexis, Bertrand, Anne, Funkiewiez, Aurélie, Rinaldi, Daisy, Saracino, Dario, Colliot, Olivier, Sayah, Sabrina, Prix, Catharina, Wlasich, Elisabeth, Wagemann, Olivia, Bordelon, Yvette, Loosli, Sandra, Schönecker, Sonja, Hoegen, Tobias, Lombardi, Jolina, Anderl-Straub, Sarah, Rollin, Adeline, Kuchcinski, Gregory, Bertoux, Maxime, Lebouvier, Thibaud, Deramecourt, Vincent, Botha, Hugo, Santiago, Beatriz, Duro, Diana, Leitão, Maria João, Almeida, Maria Rosario, Tábuas-Pereira, Miguel, Afonso, Sónia, Dickerson, Bradford C, Domoto-Reilly, Kimiko, Fields, Julie A, Foroud, Tatiana, Gavrilova, Ralitza, Heuer, Hilary W, Geschwind, Daniel, Ghoshal, Nupur, Goldman, Jill, Graff-Radford, Jonathon, Graff-Radford, Neill, Grossman, Murray, Hall, Matthew G H, Hsiung, Ging-Yuek, Huey, Edward D, Irwin, David, Russell, Lucy L, Jones, David T, Kantarci, Kejal, Kaufer, Daniel, Knopman, David S, Kremers, Walter, Lago, Argentina Lario, Lapid, Maria I, Litvan, Irene, Lucente, Diane, Mackenzie, Ian R, Cobigo, Yann, Mendez, Mario F, Mester, Carly, Miller, Bruce L, Onyike, Chiadi U, Ramanan, Vijay K, Ramos, Eliana Marisa, Rao, Meghana, Rascovsky, Katya, Rankin, Katherine P, Wolf, Amy, Roberson, Erik D, Savica, Rodolfo, Tartaglia, M Carmela, Wong, Bonnie, Cash, David M, Bouzigues, Arabella, Swift, Imogen J, Peakman, Georgia, Bocchetta, Martina, Goh, Sheng-Yang Matt, Todd, Emily G, Convery, Rhian S, Rowe, James B, Borroni, Barbara, Galimberti, Daniela, Tiraboschi, Pietro, Masellis, Mario, Finger, Elizabeth, van Swieten, John C, Seelaar, Harro, Petrucelli, Leonard, Jiskoot, Lize C, Sorbi, Sandro, Butler, Chris R, Graff, Caroline, Gerhard, Alexander, Langheinrich, Tobias, Laforce, Robert, Sanchez-Valle, Raquel, de Mendonça, Alexandre, Moreno, Fermin, Gendron, Tania F, Synofzik, Matthis, Vandenberghe, Rik, Ducharme, Simon, Le Ber, Isabelle, Levin, Johannes, Danek, Adrian, Otto, Markus, Pasquier, Florence, Santana, Isabel, Kornak, John
Publikováno v:
Nature medicine
Nature medicine 28(10), 2194-2206 (2022). doi:10.1038/s41591-022-01942-9
Nature Medicine, 28(10), 2194-2206. Nature Publishing Group
Nat Med
Nature medicine 28(10), 2194-2206 (2022). doi:10.1038/s41591-022-01942-9
Nature Medicine, 28(10), 2194-2206. Nature Publishing Group
Nat Med
Data availability: The datasets analyzed for the current study reflect collaborative efforts of two research consortia: ALLFTD and GENFI. Each consortium provides clinical data access based on established policies for data use: processes for request
Autor:
Peters, Jaime L., Rushton, Lesley, Sutton, Alex J., Jones, David R., Abrams, Keith R., Mugglestone, Moira A.
Publikováno v:
Journal of the Royal Statistical Society. Series C (Applied Statistics), 2005 Jan 01. 54(1), 159-172.
Externí odkaz:
https://www.jstor.org/stable/3592605
Autor:
Mulcahy, Victoria, Liaskou, Evaggelia, Martin, Jose-Ezequiel, Kotagiri, Prasanti, Badrock, Jonathan, Jones, Rebecca L, Rushbrook, Simon M, Ryder, Stephen D, Thorburn, Douglas, Taylor-Robinson, Simon D, Clark, Graeme, Cordell, Heather J, Sandford, Richard N, Jones, David E, Hirschfield, Gideon M, Mells, George F
BACKGROUND AIMS: In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid-the UDCA response-accurately predicts long-term outcome. Molecular characterization of patients stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c4650dcfe83fc846a60f2d69afe4ce
http://hdl.handle.net/10044/1/103338
http://hdl.handle.net/10044/1/103338
Autor:
Mynarek, Martin, Obrecht, Denise, Sill, Martin, Sturm, Dominik, Kloth-Stachnau, Katja, Selt, Florian, Ecker, Jonas, von Hoff, Katja, Juhnke, Björn-Ole, Goschzik, Tobias, Pietsch, Torsten, Bockmayr, Michael, Kool, Marcel, von Deimling, Andreas, Witt, Olaf, Schüller, Ulrich, Benesch, Martin, Gerber, Nicolas U, Sahm, Felix, Jones, David T W, Korshunov, Andrey, Pfister, Stefan M, Rutkowski, Stefan, Milde, Till
Publikováno v:
Mynarek, M, Obrecht, D, Sill, M, Sturm, D, Kloth-Stachnau, K, Selt, F, Ecker, J, von Hoff, K, Juhnke, B-O, Goschzik, T, Pietsch, T, Bockmayr, M, Kool, M, von Deimling, A, Witt, O, Schüller, U, Benesch, M, Gerber, N U, Sahm, F, Jones, D T W, Korshunov, A, Pfister, S M, Rutkowski, S & Milde, T 2023, ' Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts ', Acta Neuropathologica, vol. 145, no. 1, pp. 97-112 . https://doi.org/10.1007/s00401-022-02522-4
Molecular groups of medulloblastoma (MB) are well established. Novel risk stratification parameters include Group 3/4 (non-WNT/non-SHH) methylation subgroups I–VIII or whole-chromosomal aberration (WCA) phenotypes. This study investigates the integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15378be79d2bda5dca23406f665e0128
https://doi.org/10.5167/uzh-228205
https://doi.org/10.5167/uzh-228205
Autor:
Keck, Michaela-Kristina, Sill, Martin, Wittmann, Andrea, Joshi, Piyush, Stichel, Damian, Beck, Pengbo, Okonechnikow, Konstantin, Sievers, Philipp, Wefers, Annika K, Roncaroli, Federico, Avula, Shivaram, McCabe, Martin G, Hayden, James T, Wesseling, Pieter, Øra, Ingrid, Nistér, Monica, Kranendonk, Mariëtte EG, Tops, Bastiaan BJ, Zapotocky, Michal, Zamecnik, Josef, Vasiljevic, Alexandre, Fenouil, Tanguy, Meyronet, David, von Hoff, Katja, Schüller, Ulrich, Loiseau, Hugues, Figarella-Branger, Dominique, Kramm, Christof M, Sturm, Dominik, Scheie, David, Rauramaa, Tuomas, Pesola, Jouni, Gojo, Johannes, Haberler, Christine, Brandner, Sebastian, Jacques, Tom, Sexton Oates, Alexandra, Saffery, Richard, Koscielniak, Ewa, Baker, Suzanne J, Yip, Stephen, Snuderl, Matija, Ud Din, Nasir, Samuel, David, Schramm, Kathrin, Blattner-Johnson, Mirjam, Selt, Florian, Ecker, Jonas, Milde, Till, von Deimling, Andreas, Korshunov, Andrey, Perry, Arie, Pfister, Stefan M, Sahm, Felix, Solomon, David A, Jones, David TW
Publikováno v:
Acta neuropathologica, vol 145, iss 1
Pediatric central nervous system (CNS) tumors represent the most common cause of cancer-related death in children aged 0-14years. They differ from their adult counterparts, showing extensive clinical and molecular heterogeneity as well as a challengi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9e53b2c51e97e5254db25ad2e24e2e8f
https://escholarship.org/uc/item/616989d5
https://escholarship.org/uc/item/616989d5
Publikováno v:
Surgical and Radiologic Anatomy
Purpose The physicians say that the least anatomy is required for clinical practice. But the disease causes anatomical distortions or variations in structures impairing functions of organs and systems. So, the diagnosis and analysis of treatment of d
Autor:
Crable, Erika L., Benintendi, Allyn, Jones, David K., Walley, Alexander Y., Hicks, Jacqueline Milton, Drainoni, Mari-Lynn
Publikováno v:
Implementation Science, Vol 17, Iss 1, Pp 1-14 (2022)
Implementation Science : IS
Implementation Science : IS
Background Despite the important upstream impact policy has on population health outcomes, few studies in implementation science in health have examined implementation processes and strategies used to translate state and federal policies into accessi
Autor:
Sveinbjornsson, Gardar, Ulfarsson, Magnus O, Thorolfsdottir, Rosa B, Jonsson, Benedikt A, Einarsson, Eythor, Gunnlaugsson, Gylfi, Rognvaldsson, Solvi, Arnar, David O, Baldvinsson, Magnus, Bjarnason, Ragnar G, Eiriksdottir, Thjodbjorg, Erikstrup, Christian, Ferkingstad, Egil, Halldorsson, Gisli H, Helgason, Hannes, Helgadottir, Anna, Hindhede, Lotte, Hjorleifsson, Grimur, Jones, David, Knowlton, Kirk U, Lund, Sigrun H, Melsted, Pall, Norland, Kristjan, Olafsson, Isleifur, Olafsson, Sigurdur, Oskarsson, Gudjon R, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Snaebjarnarson, Auðunn S, Sigurdsson, Emil, Steinthorsdottir, Valgerdur, Schwinn, Michael, Thorgeirsson, Gudmundur, Thorleifsson, Gudmar, Jonsdottir, Ingileif, Bundgaard, Henning, Nadauld, Lincoln, Bjornsson, Einar S, Rulifson, Ingrid C, Rafnar, Thorunn, Norddahl, Gudmundur L, Thorsteinsdottir, Unnur, Sulem, Patrick, Gudbjartsson, Daniel F, Holm, Hilma, Stefansson, Kari
Publikováno v:
Sveinbjornsson, G, Ulfarsson, M O, Thorolfsdottir, R B, Jonsson, B A, Einarsson, E, Gunnlaugsson, G, Rognvaldsson, S, Arnar, D O, Baldvinsson, M, Bjarnason, R G, Eiriksdottir, T, Erikstrup, C, Ferkingstad, E, Halldorsson, G H, Helgason, H, Helgadottir, A, Hindhede, L, Hjorleifsson, G, Jones, D, Knowlton, K U, Lund, S H, Melsted, P, Norland, K, Olafsson, I, Olafsson, S, Oskarsson, G R, Ostrowski, S R, Pedersen, O B, Snaebjarnarson, A S, Sigurdsson, E, Steinthorsdottir, V, Schwinn, M, Thorgeirsson, G, Thorleifsson, G, Jonsdottir, I, Bundgaard, H, Nadauld, L, Bjornsson, E S, Rulifson, I C, Rafnar, T, Norddahl, G L, Thorsteinsdottir, U, Sulem, P, Gudbjartsson, D F, Holm, H, Stefansson, K & DBDS Genomic Consortium 2022, ' Multiomics study of nonalcoholic fatty liver disease ', Nature Genetics, vol. 54, no. 11, pp. 1652-1663 . https://doi.org/10.1038/s41588-022-01199-5
DBDS Genomic Consortium 2022, ' Multiomics study of nonalcoholic fatty liver disease ', Nature Genetics, vol. 54, pp. 1652–1663 . https://doi.org/10.1038/s41588-022-01199-5
DBDS Genomic Consortium 2022, ' Multiomics study of nonalcoholic fatty liver disease ', Nature Genetics, vol. 54, pp. 1652–1663 . https://doi.org/10.1038/s41588-022-01199-5
Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and integrated the findings with expression and proteomic data. For NAFL, we u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fc8772fb9337ecbc8c280a01928fea
https://pure.au.dk/portal/da/publications/multiomics-study-of-nonalcoholic-fatty-liver-disease(0ef7997b-73b5-420e-accf-5d2eea901078).html
https://pure.au.dk/portal/da/publications/multiomics-study-of-nonalcoholic-fatty-liver-disease(0ef7997b-73b5-420e-accf-5d2eea901078).html
Autor:
Buhigas, Claudia, Warren, Anne Y., Leung, Wing-Kit, Whitaker, Hayley C., Luxton, Hayley J., Hawkins, Steve, Kay, Jonathan, Butler, Adam, Xu, Yaobo, Woodcock, Dan J., Merson, Sue, Frame, Fiona M., Sahli, Atef, Abascal, Federico, Gihawi, Abraham, Lambert, Adam, Thompson, Alan, Futreal, Andrew, Menzies, Andrew, Baddage, Anne, Ng, Anthony, Sahil, Atef, Kremeyer, Barbara, Al-Lazikani, Bissan, Massie, Charlie, Greenman, Christopher, Ogden, Christopher, Verrill, Clare, Fisher, Cyril, Berney, Dan, Burns, Dan, Leongamornlert, Daniel, Jones, David, Nicol, David, Wedge, David C., Cahill, Declan, Easton, Douglas, Rowe, Edward, Riabchenko, Ekaterina, Bancroft, Elizabeth, Mayer, Erik, Anokian, Ezequiel, Hamdy, Freddie, Park, Gahee, Pelvender, Gill, Leeman, Gregory, Gundem, Gunes, Zhang, Hongwei, Mills, Ian G., Zhang, Jingjing, Teague, Jon, Zamora, Jorge, Karaszi, Katalin, Raine, Kieran, Matthews, Lucy, Stebbings, Lucy, Alexandrov, Ludmil B., Marsden, Luke, Ahmed, Mahbubl, Nykter, Matti, Ghori, Mohammed, Livni, Naomi, Dennis, Nening, Van As, Nicholas, Camacho, Niedzica, Shah, Nimish, Kumar, Pardeep, Van Loo, Peter, Lach, Radoslaw, Edwards, Sandra, Pita, Sara, Field, Sarah J., Thomas, Sarah, Tavaré, Simon, Scalabrino, Stefania, Hazell, Steven, McLaren, Stuart, Visakorpi, Tapio, Mitchell, Thomas J., Dudderidge, Tim, Dadaev, Tokhir, McDermott, Ultan, Bo, Valeria, Haberland, Valeriia, Gnanapragasam, Vincent, Khoo, Vincent, Howat, William, Jie-Lu, Yong, Yu, Yongwei, Kote-Jarai, Zsofia, Martincorena, Iñigo, Bova, G. Steven, Foster, Christopher S., Campbell, Peter, Maitland, Norman J., Neal, David E., Massie, Charlie E., Lynch, Andy G., Eeles, Rosalind A., Cooper, Colin S., Brewer, Daniel S., Group, CRUK-ICGC Prostate Cancer
Publikováno v:
Buhigas, C, Warren, A Y, Leung, W-K, Whitaker, H C, Luxton, H J, Hawkins, S, Kay, J, Butler, A, Xu, Y, Woodcock, D J, Merson, S, Frame, F M, Sahli, A, Abascal, F, Gihawi, A, Lambert, A, Thompson, A, Futreal, A, Menzies, A, Baddage, A, Ng, A, Sahil, A, Kremeyer, B, Al-Lazikani, B, Massie, C, Greenman, C, Ogden, C, Verrill, C, Fisher, C, Berney, D, Burns, D, Leongamornlert, D, Jones, D, Nicol, D, Wedge, D C, Cahill, D, Easton, D, Rowe, E, Riabchenko, E, Bancroft, E, Mayer, E, Anokian, E, Hamdy, F, Park, G, Pelvender, G, Leeman, G, Gundem, G, Zhang, H, Mills, I G, Zhang, J, Teague, J, Zamora, J, Karaszi, K, Raine, K, Matthews, L, Stebbings, L, Alexandrov, L B, Marsden, L, Ahmed, M, Nykter, M, Ghori, M, Livni, N, Dennis, N, Van As, N, Camacho, N, Shah, N, Kumar, P, Van Loo, P, Lach, R, Edwards, S, Pita, S, Field, S J, Thomas, S, Tavaré, S, Scalabrino, S, Hazell, S, McLaren, S, Visakorpi, T, Mitchell, T J, Dudderidge, T, Dadaev, T, McDermott, U, Bo, V, Haberland, V, Gnanapragasam, V, Khoo, V, Howat, W, Jie-Lu, Y, Yu, Y, Kote-Jarai, Z, Martincorena, I, Bova, G S, Foster, C S, Campbell, P, Maitland, N J, Neal, D E, Massie, C E, Lynch, A G, Eeles, R A, Cooper, C S, Wedge, D C, Brewer, D S & Group, CRUK-ICGC P C 2022, ' The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates ', Molecular Cancer, vol. 21, 183 . https://doi.org/10.1186/s12943-022-01644-3
Background Up to 80% of cases of prostate cancer present with multifocal independent tumour lesions leading to the concept of a field effect present in the normal prostate predisposing to cancer development. In the present study we applied Whole Geno