Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jingwu Xie"'
Autor:
Xiaojing Zhao, Wenjing Yang, Tianming Yu, Yu Yu, Xiufang Cui, Zheng Zhou, Hui Yang, Yanbo Yu, Anthony J. Bilotta, Suxia Yao, Jimin Xu, Jia Zhou, Gregory S. Yochum, Walter A. Koltun, Austin Portolese, Defu Zeng, Jingwu Xie, Iryna V. Pinchuk, Hongjie Zhang, Yingzi Cong
Publikováno v:
Gastroenterology. 164:89-102
Intestinal fibrosis is a significant complication of Crohn's disease (CD). Gut microbiota reactive Th17 cells are crucial in the pathogenesis of CD; however, how Th17 cells induce intestinal fibrosis is still not completely understood.In this study,
Autor:
Jingwu Xie, Michael J. Klemsz, Melissa A. Kacena, George Sandusky, Xiaoli Zhang, Mark H. Kaplan
Publikováno v:
Journal of medical virology. 94(12)
Coronavirus disease 2019 (COVID-19) is the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Over 500 million confirmed cases of COVID-19 have been recorded, with six million deaths. Thus, reducing the COVID-19-related m
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has an unfavorable outcome and a high rate of relapse. Autophagy plays a vital role in the development of and therapeutic responses to leukemia. This study identif
Autor:
E. Gabriela Chiorean, Jingwu Xie, Dongsheng Gu, Beiqin Yu, Jun Wan, Xiaoli Zhang, Yanfei Jia, Yunshan Wang
Publikováno v:
Oncogene
Pancreatic cancer, mostly pancreatic ductal adenocarcinomas (PDAC), is one of the most lethal cancers, with a dismal median survival around 8 months. PDAC is notoriously resistant to chemotherapy. Thus far, numerous attempts using novel targeted ther
Publikováno v:
Molecular Carcinogenesis. 57:1608-1615
Colorectal cancer is a leading cause of cancer-related death worldwide. While early stage colorectal cancer can be removed by surgery, patients with advanced disease are treated by chemotherapy, with 5-Fluorouracil (5-FU) as a main ingredient. Howeve
Publikováno v:
Cells, Vol 10, Iss 2030, p 2030 (2021)
Cells
Cells
The hedgehog pathway, which plays a significant role in embryonic development and stem cell regulation, is activated in gastrointestinal cancers. Chemotherapy is widely used in cancer treatment. However, chemoresistance becomes a substantial obstacle
Publikováno v:
Journal of Genetics and Genomics. 44:375-383
Gastric cancer is a leading cause of cancer-related mortality worldwide, and options to treat gastric cancer are limited. Fluorouracil (5Fu)-based chemotherapy is frequently used as a neoadjuvant or an adjuvant agent for gastric cancer therapy. Most
Autor:
Dongsheng Gu, Xiaoben Liu, Seung Young Lee, Samuel Chen, Bing Song, Jingwu Xie, Shovik Bandyopadhyay, Stephen F. Konieczny, Junjie Li, Ji-Xin Cheng, Timothy L. Ratliff
Publikováno v:
Oncogene
Cancer cells are known to execute reprogramed metabolism of glucose, amino acids and lipids. Here, we report a significant role of cholesterol metabolism in cancer metastasis. By using label-free Raman spectromicroscopy, we found an aberrant accumula
Autor:
Xiaoli Zhang, Jingwu Xie
Publikováno v:
Journal of Genetics and Genomics. 43:3-10
There is high expectation for significant improvements in cancer patient care after completion of the human genome project in 2003. Through pains-taking analyses of genomic profiles in cancer patients, a number of targetable gene alterations have bee
Autor:
Jeffrey K. Wickliffe, Dongsheng Gu, Istavan Boldogh, Xiaoli Zhang, Nonggao He, James J. Salazar, Jingwu Xie
Publikováno v:
Journal of Genetics and Genomics. 42:589-596
Lung cancer causes more deaths than breast, colorectal and prostate cancers combined. Despite major advances in targeted therapy in a subset of lung adenocarcinomas, the overall 5-year survival rate for lung cancer worldwide has not significantly cha