Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan Trnka"'
Autor:
Michal Zuzčák, Jan Trnka
Publikováno v:
International Journal of Oncology. 61
Pancreatic cancer (PC) has one of the highest fatality rates and the currently available therapeutic options are not sufficient to improve its overall poor prognosis. In addition to insufficient effectiveness of anticancer treatments, the lack of cle
Autor:
Martin Šmíd, Luděk Berec, Lenka Přibylová, Ondřej Májek, Tomáš Pavlík, Jiří Jarkovský, Jakub Weiner, Tamara Barusová, Jan Trnka
Publikováno v:
The Journal of infectious diseases. 226(8)
Background The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades immunity conferred by vaccines and previous infections. Methods We used a Cox proportional hazards model and a logistic regression on individual-lev
Autor:
Luděk Berec, Tuček, Jan Trnka, Hromádková E, Josef Šlerka, Milan Zajicek, Jan Smyčka, Šoltés M, Levínský R, Petra Vidnerová, Roman Neruda, Martin Smid, Tomas Diviak
Publikováno v:
Luděk, B, Smyčka, J, Levínský, R, Hromádková, E, Šoltés, M, Šlerka, J, Tuček, V, Trnka, J, Šmíd, M, Zajíček, M, Diviak, T, Neruda, R & Vidnerová, P 2022, ' Delays, Masks, the Elderly, and Schools: First Covid-19 Wave in the Czech Republic ', Bulletin of mathematical biology . https://doi.org/10.1007/s11538-022-01031-5
medRxiv
medRxiv
The Czech Republic (or Czechia) is facing the second wave of COVID-19 epidemic, with the rate of growth in the number of confirmed cases (among) the highest in Europe. Learning from the spring first wave, when many countries implemented interventions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e2373596c99f33e5442a71d9e519db
https://doi.org/10.1101/2020.11.06.20227330
https://doi.org/10.1101/2020.11.06.20227330
Autor:
Petr Vaňhara, Sebastiano Masuri, Franziska Walter, Josef Havel, Lukáš Moráň, Jochen H. M. Prehn, Moustafa Elkalaf, Kateřina Vašíčková, Jan Trnka, Tiziana Pivetta
Publikováno v:
Metallomics : integrated biometal science. 11(9)
There is an ongoing need for the development of new cancer therapeutics that combine high cytotoxic efficiency with low side effects, and also override resistance to the first-line chemotherapeutics. Copper(ii)–phenanthroline complexes are promisin
Autor:
Michal Anděl, Tomáš Urban, G. Hege Thoresen, Petr Waldauf, František Duška, Nils Gunnar Løvsletten, Vladimír Frič, Jan Trnka, Adéla Krajčová, Moustafa Elkalaf
Publikováno v:
Critical care medicine. 46(3)
Objectives Propofol may adversely affect the function of mitochondria and the clinical features of propofol infusion syndrome suggest that this may be linked to propofol-related bioenergetic failure. We aimed to assess the effect of therapeutic propo
Autor:
Vladimir Stich, Michal Anděl, J Tůmová, Jan Gojda, Jan Trnka, Moustafa Elkalaf, Eva Krauzová, Jana Potockova, Petr Waldauf, Radka Straková, Martin Jaček, Lenka Rossmeislová, Petr Tůma
Publikováno v:
European journal of clinical nutrition. 71(5)
Branched chain amino acids (BCAA) are among nutrients strongly linked with insulin sensitivity (IS) measures. We investigated the effects of a chronic increase of BCAA intake on IS in two groups of healthy subjects differing in their basal consumptio
Autor:
Jakub Ziak, Moustafa Elkalaf, V Dzupa, Jana Pátková, Katerina Jiroutkova, Jan Trnka, František Duška, Adéla Krajčová
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 39:180-189
Glutamine has been considered essential for rapidly dividing cells, but its effect on mitochondrial function is unknown.Human myoblasts were isolated from skeletal muscle biopsy samples (n = 9) and exposed for 20 days to 6 different glutamine concent
Autor:
Kateřina Jiroutková, Jan Gojda, Adéla Krajčová, Jakub Žiak, Martin Kalous, Jan Trnka, František Duška, Michal Fric, Valér Džupa, Jana Tůmová
Publikováno v:
JPEN. Journal of parenteral and enteral nutrition. 41(7)
BACKGROUND Functional mitochondria in skeletal muscle of patients with protracted critical illness and intensive care unit-acquired weakness are depleted, but remaining mitochondria have increased functional capacities of respiratory complexes II and
Autor:
Kateřina Jiroutková, Adéla Krajčová, Moustafa Elkalaf, František Duška, Jan Trnka, Petr Waldauf, Valér Džupa, Jakub Ziak, Vlasta Němcová-Fürstová, Jan Kovář, Michal Fric, Jan Gojda
Publikováno v:
Critical Care
Background Mitochondrial damage occurs in the acute phase of critical illness, followed by activation of mitochondrial biogenesis in survivors. It has been hypothesized that bioenergetics failure of skeletal muscle may contribute to the development o
Autor:
Victoria J. Adlam, Andrew M. James, Geoffrey F. Kelso, Jordi Asin-Cayuela, Thabo Mahendiran, Robin A.J. Smith, Frances H. Blaikie, Helena M. Cochemé, Carolyn M. Porteous, Abdul-Rahman B. Manas, Michael P. Murphy, Meredith F. Ross, Jan Trnka
Publikováno v:
Mitochondrion. 7:S94-S102
Mitochondrial oxidative damage contributes to a range of degenerative diseases. Ubiquinones have been shown to protect mitochondria from oxidative damage, but only a small proportion of externally administered ubiquinone is taken up by mitochondria.