Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Duane Moogk"'
Autor:
S. Ronan Foley, Ksenia Bezverbnaya, Christopher L. Baker, Rebecca C. Turner, Jonathan L. Bramson, Jamie D. McNicol, Derek Cummings, Craig Aarts, Galina Denisova, Duane Moogk, Anthony F. Rullo, Michael Sun
Publikováno v:
Cytotherapy. 23:820-832
Background aims T cells engineered with synthetic receptors have delivered powerful therapeutic results for patients with relapsed/refractory hematologic malignancies. The authors have recently described the T-cell antigen coupler (TAC) receptor, whi
Autor:
Alan B. Frey, Ivan Liadi, William Rittase, Nicholas P. Restifo, Iman Osman, Zhiya Yu, Michelle Krogsgaard, Duane Moogk, Cheng Zhu, Navin Varadarajan, Arianne Perez-Garcia, Shi Zhong, Janna Dougherty, Victoria Fang
Publikováno v:
The Journal of Immunology. 197:644-654
CD8+ T cells develop increased sensitivity following Ag experience, and differences in sensitivity exist between T cell memory subsets. How differential TCR signaling between memory subsets contributes to sensitivity differences is unclear. We show i
Genetic associations of the interleukin locus at 1q32.1 with clinical outcomes of cutaneous melanoma
Autor:
Anuj Bapodra, Christina Adaniel, Tomas Kirchhoff, Jerry Shields, Russell S. Berman, Justin Rendleman, Anna C. Pavlick, Carlos N Martinez, David Polsky, Richard L. Shapiro, Matjaz Vogelsang, Nathaniel H. Fleming, Iman Osman, Yongzhao Shao, Ines Pires da Silva, Duane Moogk, Michelle Krogsgaard
Background Due to high melanoma immunogenicity, germline genetic variants in immune pathways have been studied for association with melanoma prognosis. However, limited candidate selection, inadequate power, or lack of independent validation have ham
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4085e140f022da766b8f46a9723d38
https://europepmc.org/articles/PMC5166523/
https://europepmc.org/articles/PMC5166523/
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 77(4)
Human embryonic stem cell (hESC) cultures are heterogeneous and constituting paracrine signals are required to maintain pluripotency. The cellular interplay and dynamic nature of this heterogeneity is not understood. Here, long-term hESC imaging and
Autor:
Jana Skorepova, John Ramunas, Lawrence Rosenberg, Stephen C. Hanley, Eric Jervis, Duane Moogk, April Blaylock
Publikováno v:
Biotechnology and bioengineering. 97(5)
A means of expanding islet cell mass is urgently needed to supplement the limited availability of donor islets of Langerhans for transplant. Live cell imaging of human islets in culture has the potential to identify the specific cells and processes i
Autor:
Arianne Perez-Garcia, Duane Moogk, Farbod Darvishian, Michelle Krogsgaard, Eleazar Vega-Saenz de Miera, Paul J. Christos, Michelle W. Ma, Erica B. Friedman, Ines Pires da Silva, Iman Osman, Nina Bhardwaj, Patrick Scanlon, Anna C. Pavlick
Publikováno v:
Journal of Translational Medicine
Background Matrix metalloproteinase-23 (MMP-23) can block the voltage-gated potassium channel Kv1.3, whose function is important for sustained Ca2+ signaling during T cell activation. MMP-23 may also alter T cell activity and phenotype through cleava