Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Companjen A"'
Autor:
Arjen Companjen, Joanne Goodman, Amanda Versteilen, Marianne Scheel Fjording, Ulrich Kunz, Philip Timmerman, Susanne Pihl, Karen Elsby, Timo Piironen, Ulf Loevgren, Paul Robinson
Publikováno v:
Bioanalysis. 9:1493-1508
The analysis of biomarkers by ligand-binding assays offers significant challenges compared with the bioanalysis of small and large molecule drugs. The presence of endogenous analyte is a commonly cited issue. Also the sourcing and application of appr
Autor:
Martin Nemansky, Laurent Vermet, Lydia Michaut, Arjen Companjen, Ralf Loebbert, Jenny Hendriks, Susanne Pihl, Janka Ryding
Publikováno v:
Bioanalysis. 6:1409-1413
Long- and short-term stability testing of the analyte is one of the key parameters in bioanalytical method validation in support of pharmacokinetics. However, for immunogenicity testing, the scientific rationale for long- and short-term stability tes
Autor:
Peter van Amsterdam, Arjen Companjen, Stephen White, Karen Elsby, Stuart McDougall, Michaela Golob, Philip Timmerman, Margarete Brudny-Kloeppel, John Smeraglia
Publikováno v:
Bioanalysis. 6:729-732
Crystal City V meeting on Quantitative Bioanalytical Method Validation and Implementation: 2013 Revised US FDA Guidance 3–5 December 2013, Hilton Baltimore, MD, USA The meeting provided an opportunity for Industry and regulators from the US FDA to
Publikováno v:
Clinical Otolaryngology. 39:39-44
Objective To evaluate the long-term efficacy of the Epley manoeuvre as a therapeutic procedure for posterior canal benign paroxysmal positional vertigo. Design Randomised, double-blind, sham-controlled trial. Setting A multidisciplinary dizziness uni
Autor:
Begona Barroso, Christian Herling, Stephanie Fischmann, Neil Henderson, Philip Timmerman, Karen Elsby, Clare Kingsley, Susanne Pihl, Birgit Jaitner, Ulrich Kunz, Amanda Versteilen, Stewart Bates, Daniela Stoellner, Arjen Companjen
Publikováno v:
Bioanalysis. 4:1883-1894
Biomarkers have become increasingly important in drug development and many bioanalysts are getting involved. Consequently, different views on how to approach the bioanalysis of biomarkers have been published or are being developed. The European Bioan
Publikováno v:
International Immunology. 14:669-676
CD40 ligation by CD40 ligand(+) CD4(+) T cells has been claimed to be involved in inflammatory responses in human skin. However, these data are derived from in vitro cell culture systems and immunohistochemistry, and the mechanisms involved have not
Publikováno v:
Archives of Dermatological Research. 293:184-190
To investigate the immunological function of cells in normal and diseased skin under conditions approximating the in vivo situation, it is necessary to maintain the structural integrity of the tissue. To achieve this, freshly isolated skin has to be
Publikováno v:
Journal of Histochemistry & Cytochemistry, 48(1), 95-103. Histochemical Society Inc.
Integral immunohistochemical analysis of immune responses in frozen sections requires that, in addition to constitutively expressed membrane CD markers, less stable determinants can be reliably visualized. Therefore, we compared the commonly used ace
Autor:
Margarete Brudny-Kloeppel, Arjen Companjen, Hans Mulder, Benno Ingelse, John Smeraglia, Philip Timmerman, Neil Henderson
Publikováno v:
Bioanalysis. 5(2)
On 12–13 June 2012, the European Bioanalysis Forum hosted its third Focus Meeting in Brussels (Belgium). At the meeting, a panel discussion was held on the hurdles that the bioanalytical community encounters when adopting new technologies or managi
Autor:
Alexander Berthold Hendrik Bakker, Stefan Kostense, Cathleen A. Hanlon, Rie von Eyben, Susan M. Moore, Arjen Companjen, Wilfred E. Marissen, Gerrit Jan Weverling, Jaap Goudsmit
Publikováno v:
Antimicrobial agents and chemotherapy, 56(7), 3524-3530. American Society for Microbiology
Monoclonal antibodies are successful biologics in treating a variety of diseases, including the prevention or treatment of viral infections. CL184 is a 1:1 combination of two human monoclonal IgG1 antibodies (CR57 and CR4098) against rabies virus, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ec33b653fe3424812a0cce0e0a3579
https://europepmc.org/articles/PMC3393455/
https://europepmc.org/articles/PMC3393455/