Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Christian Sell"'
Autor:
Antonello Lorenzini, Christian Sell
Publikováno v:
Aging (Albany NY)
Cellular senescence is a biological phenomenon that has received many interpretations since its original description by Hayflick and Moorhead in 1961. A hypothesis proposed over 40 years ago is now generally accepted: i.e. that cellular senescence is
Autor:
Christian Sell
Publikováno v:
Aging (Albany NY)
GeroScience
GeroScience
Aging is a major risk factor for the majority of human diseases, and the development of interventions to reduce the intrinsic rate of aging is expected to reduce the risk for age-related diseases including cardiovascular disease, cancer, and dementia
Autor:
Carlos S. Reyna-Blanco, Vanessa Carina Bieker, Detlef Jantzen, Christoph Leuenberger, Joachim Burger, Yoan Diekmann, Daniel Wegmann, Anna Schulz, Laura Winkelbach, Elke Kaiser, Jens Blöcher, Gundula Lidke, Jörg Orschiedt, Thomas Terberger, Zoé Pochon, Thomas S. Bertino, Mark G. Thomas, Amelie Scheu, Ute Brinker, Krishna R. Veeramah, Christian Sell, Vivian Link, Ruth Bollongino, Sofija Stefanović, Aleksandra Žegarac, Zuzana Hofmanová
Publikováno v:
Current Biology
Lactase persistence (LP), the continued expression of lactase into adulthood, is the most strongly selected single gene trait over the last 10,000 years inmultiple human populations. It has been posited that the primary allele causing LP among Eurasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f04d11782b17fc47dde194c839150e3
https://zenodo.org/record/5751837
https://zenodo.org/record/5751837
Autor:
Sascha Willuweit, Thorsten Hadrys, Lutz Roewer, Steffi Bredemeyer, Titia Sijen, Natalie E.C. Weiler, Sabrina Achtruth, Marc Trimborn, Ingo Bastisch, Christian Sell, F.-X. Laurent, Petra Müller, Walther Parson, Johannes Hedman, Maja Sidstedt
Publikováno v:
International Journal of Legal Medicine
We present results from an inter-laboratory massively parallel sequencing (MPS) study in the framework of the SeqForSTRs project to evaluate forensically relevant parameters, such as performance, concordance, and sensitivity, using a standardized seq
Autor:
Claudio Torres, Michael Bene, Christian Sell, Ashley Azar, Timothy Nacarelli, Gregg J. Johannes, Ibiyonu Lawrence, Justin Cohen
Publikováno v:
GeroScience. 40:193-199
Cellular senescence is a central component of the aging process. This cellular response has been found to be induced by multiple forms of molecular damage and senescent cells increase in number with age in all tissues examined to date. We have examin
Autor:
Lucy van Dorp, Garrett Hellenthal, Joachim Burger, Zuzana Hofmanová, Krishna R. Veeramah, Jens Blöcher, Christian Sell, Vivian Link, Bernd Päffgen, Brigitte Haas-Gebhard, Bernd Trautmann, Anja Gairhos, Jochen Haberstroh, Michaela Harbeck, Daniel Wegmann, Joris Peters, Saioa López, Andreas Rott, Melanie Groß, Karola Kirsanow
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Many modern European states trace their roots back to a period known as the Migration Period that spans from Late Antiquity to the early Middle Ages. We have conducted the first population-level analysis of people from this era, generati
Autor:
Christian Sell, Timothy Nacarelli
Publikováno v:
Molecular and Cellular Endocrinology. 455:83-92
Cellular senescence has gained much attention as a contributor to aging and susceptibility to disease. Senescent cells undergo a stable cell cycle arrest and produce pro-inflammatory cytokines. However, an additional feature of the senescence phenoty
Autor:
Gianluca Storci, Silvia Marchionni, Claudio Franceschi, Eleonora Croco, Thomas D. Stamato, Massimiliano Bonafè, Antonello Lorenzini, Christian Sell
Publikováno v:
Biogerontology
In evolutionary terms, life on the planet has taken the form of independently living cells for the majority of time. In comparison, the mammalian radiation is a relatively recent event. The common mammalian ancestor was probably small and short-lived
Autor:
Johannes Zimmermann, Henriette Löffler-Stastka, Guenther Klug, Christian Sell, Dorothea Huber
Publikováno v:
Bulletin of the Menninger Clinic. 83(4)
The study aimed to test whether countertransference reactions contain valid information about the patient. The authors examined whether a significant part of the variance in emotional, cognitive, and motivational responses to recorded therapy session
Publikováno v:
Gerontology. 66(3)
Across species, development and longevity are tightly linked. We discuss the relevant literature and suggest that the root for this stringent relationship is the rate of development. The basis for the relationship between rate of development and long