Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carmen Fonseca"'
Autor:
Emma Derrett-Smith, Christopher P. Denton, Jennifer Harvey, Alper Sari, Voon H Ong, Svetlana I. Nihtyanova, Anna Leslie, Carmen Fonseca
Publikováno v:
Arthritis & Rheumatology. 72:465-476
OBJECTIVE To describe the associations between autoantibodies, clinical presentation, and outcomes among patients with systemic sclerosis (SSc) in order to develop a novel SSc classification scheme that would incorporate both antibodies and the cutan
Autor:
Svetlana I. Nihtyanova, Sandra G. Guerra, Harry Chinque, Javier Calle Martín, Voon H Ong, Markella Ponticos, David González-Serna, Mark Harber, Carmen Fonseca, Edward P. Stern, Christopher P. Denton, Aine Burns, Shervin Assassi, Maureen D. Mayes, Korsa Khan, Vanessa Acquaah
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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ObjectiveScleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc) strongly associated with anti-RNA polymerase III antibody (ARA) autoantibodies. We investigated genetic susceptibility and altered protein expressi
Autor:
Athina, Dritsoula, Ioannis, Papaioannou, Sandra G, Guerra, Carmen, Fonseca, Javier, Martin, Ariane L, Herrick, David J, Abraham, Christopher P, Denton, Markella, Ponticos
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 70(6)
NKX2-5 is a homeobox transcription factor that is required for the formation of the heart and vessels during development, with significant postnatal down-regulation and reactivation in disease states, characterized by vascular remodeling. The purpose
Autor:
Ariane L. Herrick, Manuel Rubio-Rivas, Carmen Fonseca, Jeska K de Vries-Bouwstra, Gianluca Moroncini, Elena López-Isac, José Andrés Román-Ivorra, Norberto Ortego-Centeno, Esther F. Vicente, C. Tolosa, Alexandre E. Voskuyl, Lorenzo Beretta, Maureen D. Mayes, Lara Bossini-Castillo, Ana B. Palma, G. Riemekasten, Javier Martín, Carmen P. Simeon, Christopher P. Denton, Timothy R D J Radstake, Jörg H W Distler, Nicolas Hunzelmann, Shervin Assassi
Publikováno v:
López-Isac, E, Bossini-Castillo, L, Palma, A B, Assassi, S, Mayes, M D, Simeón, C P, Ortego-Centeno, N, Vicente, E, Tolosa, C, Rubio-Rivas, M, Román-Ivorra, J A, Beretta, L, Moroncini, G, Hunzelmann, N, Distler, J H W, Riemekasten, G, de Vries-Bouwstra, J, Voskuyl, A E, Radstake, T R D J, Herrick, A, Denton, C P, Fonseca, C & Martín, J 2017, ' Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort ', Arthritis and Rheumatology, vol. 69, no. 6, pp. 1337-1338 . https://doi.org/10.1002/art.40058
Arthritis and Rheumatology, 69(6), 1337-1338. John Wiley and Sons Ltd
Arthritis and Rheumatology, 69(6), 1337-1338. John Wiley and Sons Ltd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5aa967406fe69c0e02e38c27057d46
https://research.vumc.nl/en/publications/cb4ccbc8-f487-4889-8366-51dc7fc6871e
https://research.vumc.nl/en/publications/cb4ccbc8-f487-4889-8366-51dc7fc6871e
Autor:
Maureen D. Mayes, Gabriela Riemekasten, Alexandre E. Voskuyl, V. Fonollosa, Jane Worthington, Madelon C. Vonk, Miguel A. González-Gay, Christopher P. Denton, José Luis Callejas-Rubio, Alexander Kreuter, Javier Martin, F. David Carmona, Annemie J. Schuerwegh, Jasper C A Broen, Patricia Carreira, Rajan Madhok, Timothy R D J Radstake, Paul G. Shiels, Lina-Marcela Diaz-Gallo, Frank C. Arnett, Jörg H W Distler, Carmen P. Simeon, Nicolas Hunzelmann, Jacob M van Laar, Torsten Witte, Filemon K. Tan, M. Carmen Cénit, Carmen Fonseca, Shervin Assassi, Ariane L. Herrick, Francisco Javier López-Longo
Publikováno v:
Carmona, F D, Cenit, M C, Diaz-Gallo, L M, Broen, J C A, Simeon, C P, Carreira, P E, Callejas-Rubio, J L, Fonollosa, V, Lopez-Longo, F J, Gonzalez-Gay, M A, Hunzelmann, N, Riemekasten, G, Witte, T, Kreuter, A, Distler, J H W, Madhok, R, Shiels, P, van Laar, J M, Schuerwegh, A J, Vonk, M C, Voskuyl, A E, Fonseca, C, Denton, C P, Herrick, A, Worthington, J, Arnett, F C, Tan, F K, Assassi, S, Radstake, T R D J, Mayes, M D & Martin, J 2013, ' New insight on the Xq28 association with systemic sclerosis ', Annals of the Rheumatic Diseases, vol. 72, no. 12, pp. 2032-2038 . https://doi.org/10.1136/annrheumdis-2012-202742
Annals of the Rheumatic Diseases, 72, 12, pp. 2032-8
Annals of the Rheumatic Diseases, 72(12), 2032-2038. BMJ Publishing Group
Annals of the Rheumatic Diseases, 72, 2032-8
Annals of the Rheumatic Diseases, 72, 12, pp. 2032-8
Annals of the Rheumatic Diseases, 72(12), 2032-2038. BMJ Publishing Group
Annals of the Rheumatic Diseases, 72, 2032-8
ObjectiveTo evaluate whether the systemic sclerosis (SSc)-associated IRAK1 non-synonymous single-nucleotide polymorphism rs1059702 is responsible for the Xq28 association with SSc or whether there are other independent signals in the nearby methyl-Cp
Autor:
Huzaifa Adamali, Carmel Stock, Philip L. Molyneaux, Hiroe Sato, David Abraham, Winston Banya, Carmen Fonseca, Athol U. Wells, Anne-Marie Russell, Toby M. Maher, Gisela E. Lindahl, David M. Hansell, Christopher P. Denton, Elisabetta A. Renzoni, Andrew G. Nicholson
Publikováno v:
Thorax. 68:436-441
Background A polymorphism (rs35705950) 3 kb upstream of MUC5B , the gene encoding Mucin 5 subtype B, has been shown to be associated with familial and sporadic idiopathic pulmonary fibrosis (IPF). We set out to verify whether this variant is also a r
Autor:
Behrooz Z, Alizadeh, Jasper, Broen, Blanca, Rueda, Roger, Hesselstrand, Dirk, Wuttge, Carmen, Simeon, Norberto, Ortego-Centeno, Miguel A, Gonzalez-Gay, Miguel, Gonzalez-Gay, Anna, Pros, Ariane, Herrick, Jane, Worthington, Christopher, Denton, Carmen, Fonseca, Gabriela, Riemekasten, Madelon C, Vonk, Frank, van den Hoogen, Serena, Guiducci, Marco, Matucci-Cerinic, Rafaella, Scorza, Lorenzo, Beretta, Paolo, Airó, Marieke, Coenen, Javier, Martin, Bobby P C, Koeleman, Timothy R D J, Radstake
Publikováno v:
The Journal of Rheumatology, 37, 1673-9
The Journal of Rheumatology, 37, 8, pp. 1673-9
The Journal of Rheumatology, 37, 8, pp. 1673-9
Objective.To investigate the possible role ofFCGR2A519A>G andFCGR3A559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype.Methods.A total of 1566 patients with SSc and 2271 ge
Publikováno v:
Current Vascular Pharmacology. 7:34-39
Raynaud's phenomenon (RP) results from an exaggerated cutaneous vasospastic response to cold or emotional stress. The mechanisms that lead to impaired cutaneous vascular tone are complex. The regulation of cutaneous vasoconstriction and vasodilation,
Autor:
Neil McHugh, Piersante Sestini, Carol M. Black, Christopher C. Bunn, Anna L. Lagan, Christopher P. Denton, Ken Welsh, Carmen Fonseca, Panagiotis Pantelidis, David Abraham, Ron M. Du Bois, Elizabeth Renzoni
Publikováno v:
Arthritis & Rheumatism. 54:3034-3042
Objective To evaluate the distribution of polymorphisms in the endothelin 1 (EDN1), endothelin receptor A (EDNRA) and endothelin receptor B (EDNRB) genes in systemic sclerosis (SSc; scleroderma) and SSc subsets. Methods Two hundred five patients with
Autor:
Panagiotis Pantelidis, P. Beirne, R M du Bois, Carmen Fonseca, EA Renzoni, Carol M. Black, A. L. Lagan, Christopher P. Denton, Anne Taegtmeyer, Kenneth I. Welsh, AU Wells
Publikováno v:
Rheumatology. 44:197-201
Objective SPARC (secreted protein, acidic and rich in cysteine) is a matricellular protein that modulates cell-cell and cell-extracellular matrix interactions. SPARC expression is restricted mainly to sites of tissue remodelling and wound repair, and