Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Aleksandar Milosavljevic"'
Autor:
Kilannin Krysiak, Arpad M. Danos, Susanna Kiwala, Joshua F. McMichael, Adam C. Coffman, Erica K. Barnell, Lana Sheta, Jason Saliba, Cameron J. Grisdale, Lynzey Kujan, Shahil Pema, Jake Lever, Nicholas C. Spies, Andreea Chiorean, Damian T. Rieke, Kaitlin A. Clark, Payal Jani, Hideaki Takahashi, Peter Horak, Deborah I. Ritter, Xin Zhou, Benjamin J. Ainscough, Sean Delong, Mario Lamping, Alex R. Marr, Brian V. Li, Wan-Hsin Lin, Panieh Terraf, Yasser Salama, Katie M. Campbell, Kirsten M. Farncombe, Jianling Ji, Xiaonan Zhao, Xinjie Xu, Rashmi Kanagal-Shamanna, Kelsy C. Cotto, Zachary L. Skidmore, Jason R. Walker, Jinghui Zhang, Aleksandar Milosavljevic, Ronak Y. Patel, Rachel H. Giles, Raymond H. Kim, Lynn M. Schriml, Elaine R. Mardis, Steven J. M. Jones, Gordana Raca, Shruti Rao, Subha Madhavan, Alex H. Wagner, Obi L. Griffith, Malachi Griffith
Publikováno v:
Nat Cancer
As guidelines, therapies, and literature on cancer variants expand, the lack of consensus variant interpretations impedes clinical applications. CIViC is a public domain, crowd-sourced, and adaptable knowledgebase of evidence for the Clinical Interpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed50e6a9356f3f2f4e3e63d326c2871
https://eprints.gla.ac.uk/279775/1/279775.pdf
https://eprints.gla.ac.uk/279775/1/279775.pdf
Autor:
Lillian R. Thistlethwaite, Xiqi Li, Lindsay C. Burrage, Kevin Riehle, Joseph G. Hacia, Nancy Braverman, Michael F. Wangler, Marcus J. Miller, Sarah H. Elsea, Aleksandar Milosavljevic
Publikováno v:
Scientific Reports. 12
Untargeted metabolomics is a global molecular profiling technology that can be used to screen for inborn errors of metabolism (IEMs). Metabolite perturbations are evaluated based on current knowledge of specific metabolic pathway deficiencies, a manu
Autor:
Clémentine Decamps, Florian Privé, Raphael Bacher, Daniel Jost, Arthur Waguet, HADACA consortium, Eugene Andres Houseman, Eugene Lurie, Pavlo Lutsik, Aleksandar Milosavljevic, Michael Scherer, Michael G. B. Blum, Magali Richard
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-15 (2020)
BMC Bioinformatics
BMC Bioinformatics, BioMed Central, 2020, 21 (1), ⟨10.1186/s12859-019-3307-2⟩
BMC Bioinformatics
BMC Bioinformatics, BioMed Central, 2020, 21 (1), ⟨10.1186/s12859-019-3307-2⟩
Background Cell-type heterogeneity of tumors is a key factor in tumor progression and response to chemotherapy. Tumor cell-type heterogeneity, defined as the proportion of the various cell-types in a tumor, can be inferred from DNA methylation of sur
Autor:
William J. Craigen, Brett H. Graham, Sarah H. Elsea, Brendan Lee, Sandesh C.S. Nagamani, Lillian R. Thistlethwaite, Qin Sun, Adam D. Kennedy, V. Reid Sutton, Aleksandar Milosavljevic, Bridget M. Stroup, Fernando Scaglia, Marcus J. Miller, Lindsay C. Burrage
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics
Purpose: Untargeted metabolomic analysis is increasingly being used in the screening and management of individuals with inborn errors of metabolism (IEM). We aimed to test whether untargeted metabolomic analysis in plasma might be useful for monitori
Autor:
Sarah H. Elsea, Xiqi Li, Aleksandar Milosavljevic, Fernando Scaglia, Liona C. Poon, Kypros H. Nicolaides, Chi Chiu Wang, Argyro Syngelaki
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 78(5)
Preeclampsia, characterized by the onset of hypertension with significant proteinuria after 20 weeks’ gestation, is one of the leading causes of maternal and perinatal morbidity and mortality. Prophylactic low-dose aspirin treatment reduces the rat
Publikováno v:
Oncogene
Although head and neck squamous cell carcinoma (HNSCC) has in the past been largely associated with tobacco use, human papillomavirus (HPV+) oropharynx cancer has in recent years emerged as the fastest growing type of HNSCC. Patients with HPV+ HNSCC
Autor:
Sharon E. Plon, Lillian Ashmore, Aleksandar Milosavljevic, Peter B. McGarvey, Jimmy Zhen, Selina S. Dwight, Chris Bizon, Bradford C. Powell, Neethu Shah, Robert R. Freimuth, Clinical Genome (ClinGen) Resource, Piotr Pawliczek, Tristan Nelson, Matthew Wright, Ronak Y. Patel, Melissa J. Landrum, Sameer Paithankar, Andrew R. Jackson, Larry Babb, Natasha T. Strande
Publikováno v:
Human Mutation
Effective exchange of information about genetic variants is currently hampered by the lack of readily available globally unique variant identifiers that would enable aggregation of information from different sources. The ClinGen Allele Registry addre
Autor:
Dalton K, Preston Cg, Steven M. Harrison, Lawrence J. Babb, Bryan Wulf, Heidi L. Rehm, Selina S. Dwight, Jimmy Zhen, J. M. Cherry, Deborah I. Ritter, Kristy Lee, Erin Rooney Riggs, Madhavrao R, Cheng S, Jessica L. Mester, Ronak Y. Patel, Matthew Wright, Tong H, Jennifer L. Goldstein, Carlos Bustamante, Julianne M. O’Daniel, Xi Luo, Hannah Wand, Cheung G, Helio A. Costa, Zastrow Db, Jonathan S. Berg, Mandell Me, Sai Lakshmi Subramanian, Sharon E. Plon, Alice B. Popejoy, Arturo Lopez Pineda, Michael A. Iacocca, Marina T. DiStefano, Aleksandar Milosavljevic
Publikováno v:
Genome Medicine
Genome Medicine, Vol 14, Iss 1, Pp 1-12 (2022)
Genome Medicine, Vol 14, Iss 1, Pp 1-12 (2022)
Background Identification of clinically significant genetic alterations involved in human disease has been dramatically accelerated by developments in next-generation sequencing technologies. However, the infrastructure and accessible comprehensive c
Autor:
Xiqi Li, Lillian R. Thistlethwaite, Sarah H. Elsea, Varduhi Petrosyan, Aleksandar Milosavljevic, Marcus J. Miller
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 1, p e1008550 (2021)
PLoS Computational Biology, Vol 17, Iss 1, p e1008550 (2021)
We consider the following general family of algorithmic problems that arises in transcriptomics, metabolomics and other fields: given a weighted graph G and a subset of its nodes S, find subsets of S that show significant connectedness within G. A sp
Autor:
Sonja Suvakov, Hajrunisa Cubro, Joseph P. Grande, Fouad T. Chebib, Tamara Tchkonia, Haitao Tu, James L. Kirkland, Wendy M. White, Ranine Ghamrawi, Yvonne S. Butler Tobah, Aleksandar Milosavljevic, Yi Zhu, Natasa Milic, Vesna D. Garovic, Larissa G.P. Langhi Prata, Julie M. Cunningham, Karl A. Nath
Publikováno v:
EBioMedicine
EBioMedicine, Vol 70, Iss, Pp 103536-(2021)
EBioMedicine, Vol 70, Iss, Pp 103536-(2021)
Background Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria and/or multisystem involvement. Disease-specific therapy has yet to be developed due to the lack of understanding of underlying mechanism(s). We postul