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pro vyhledávání: '"Sabina Kaczanowska"'
Autor:
Kenisha Younger, Alexnder Tsai, Sabina Kaczanowska, Augusto C. Ochoa, Degui Geng, Eduardo Davila, Aaron P. Rapoport, Suzanne Ostrand-Rosenberg
The tumor microenvironment counters antitumor T-cell responses, in part, by blunting their activation and infiltration. Ligands that engage Toll-like receptors (TLR) on T cells and antigen-presenting cells can act as potent immune adjuvants. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9d304ac112bfa655a8110ee89c41be
https://europepmc.org/articles/PMC4433615/
https://europepmc.org/articles/PMC4433615/
Publikováno v:
Journal of leukocyte biology. 93(6)
Review on the ability of different TLR agonists to orchestrate antitumor immune responses, or promote tumor growth, underscoring the impact of choosing among TLR agonists when applying these therapies in the clinic. Various TLR agonists are currently