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pro vyhledávání: '"Colin Love"'
Autor:
Colin Love, Agnieszka Michael, J. C. Hu, Hardev Pandha, Robert Coffin, Neil Steven, C. Coombes, C. J. Davis, Nicholas D. James, Jan Steiner
Publikováno v:
Journal of Clinical Oncology. 23:3099-3099
3099 OncoVEXGM-CSF is a second generation oncolytic HSV expressing GM-CSF. Deletion of ICP34.5 provides tumour selectivity. Oncolytic potency is increased using a clinical virus strain, and by expr...
Autor:
Colin Love, J. Simpson, N. J. Graham, N. Groves, R. C. Coombes, Hardev Pandha, P. J. Guest, Claire A. Shorrock, Nicholas D. James, Jennifer Hu, C. J. Davis, Agnieszka Michael, Christopher M. Nutting, R. S. Coffin, Iain A. McNeish, Kevin J. Harrington, Jan Steiner, L. C. Medley, Neil Steven
Publikováno v:
Molecular Therapy. 11:S438
OncoVEXGM-CSF is a second generation oncolytic HSV expressing GM-CSF. Deletion of ICP34.5 provides tumour selectivity, a modification extensively studied elsewhere. Compared to previous oncolytic HSV, oncolytic potency is increased using a clinical v