Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Massimo Pettoello-Mantovani"'
Autor:
Kristin Osiecki, Jian Hua Zheng, Raynal C. Squires, Massimo Pettoello-Mantovani, Harris Goldstein, Laiping Xie
Publikováno v:
AIDS Research and Human Retroviruses. 21:125-139
HIV-1-infected monocyte/macrophages located in lymph nodes and tissues are highly productive sources of HIV-1 and may function as a persistent reservoir contributing to the rebound viremia observed after highly active antiretroviral therapy is stoppe
Autor:
Massimo Pettoello-Mantovani, Thomas Graf, Roberto Posada, Harris Goldstein, Michael H. Sieweke
Publikováno v:
AIDS Research and Human Retroviruses. 16:1981-1989
Activity of the distal region of the human immunodeficiency virus (HIV-1) long terminal repeat (LTR), which contains binding sites for the Ets-1 and USF-1 proteins, is integral for HIV-1 replication. The Ets-1 and USF-1 proteins play a critical role
Publikováno v:
AIDS Research and Human Retroviruses. 15:1639-1652
To investigate the mechanism of HIV-1-induced hematopoietic abnormalities, we examined the effect of HIV-1 infection on the in vitro and in vivo behavior of precursor cells obtained from human fetal bone marrow (HFBM). After infection with the monocy
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 19:145-149
OBJECTIVE: Individuals homozygous for a deletion in the CCR5 gene (CCR5delta32/CCR5delta32) are resistant to HIV infection, indicating that this particular chemokine receptor plays a crucial role in the initiation of in vivo HIV infection. We investi
Autor:
Christina Raker, Massimo Pettoello-Mantovani, Tobias R. Kollmann, Sergey Yurasov, Hugh Wiltshire, Harris Goldstein, Ana Kim, Nikos F. Katopodis
Publikováno v:
The Journal of Infectious Diseases. 177:337-346
Modified, human immunodeficiency virus (HIV)-inoculated thy/liv-SCID-hu mice were used to evaluate the in vivo efficacy of antiretroviral drugs. Ritonavir treatment alone initially suppressed plasma viremia, but the viremia recurred with the appearan
Autor:
Christina Raker, Massimo Pettoello-Mantovani, Sergey Yurasov, Ronald A. DePinho, James W. Horner, Jessie Browning, Harris Goldstein
Publikováno v:
Proceedings of the National Academy of Sciences. 94:14637-14641
HIV entry into human cells is mediated by CD4 acting in concert with one of several members of the chemokine receptor superfamily. The resistance to HIV infection observed in individuals with defective CCR5 alleles indicated that this particular chem
Publikováno v:
AIDS Research and Human Retroviruses. 10:1079-1087
High concentrations of the cryptococcal capsular polysaccharide (CCP) are present in the serum, cerebrospinal fluid or both in the majority of AIDS patients infected with Cryptococcus neoformans. Because the prognosis of AIDS patients infected with c
Autor:
Xiajun Zhuang, Tobias R. Kollmann, Ana Kim, Massimo Pettoello-Mantovani, Arye Rubinstein, Moshe Hachamovitch, Pam Smarnworawong, Harris Goldstein
Publikováno v:
The Journal of Experimental Medicine
A small animal model that could be infected with human immunodeficiency virus 1 (HIV-1) after peripheral inoculation would greatly facilitate the study of the pathophysiology of acute HIV-1 infection. The utility of SCID mice implanted with human fet
Autor:
Tobias R. Kollmann, Harris Goldstein, Massimo Pettoello-Mantovani, Theresa A. Calvelli, Arye Rubinstein
Publikováno v:
AIDS. 5:1447-1452
The risk of infection by HIV-1 through transfusion of contaminated blood products has been markedly decreased but not eliminated by serological screening of donors. Methods are required to further minimize or eliminate the risk of infection of blood
Autor:
Massimo Pettoello-Mantovani, Kristin Osiecki, Meng Liang Zhao, Sunhee Choi Lee, Jinglin Sun, Lillie Lopez, Harris Goldstein, Christina M. Anderson, Joan W. Berman, Emilie Jeanne Wang
Publikováno v:
AIDS research and human retroviruses. 19(9)
A large body of evidence has indicated that microglia are the predominant cellular location for HIV-1 in the brains of HIV-1-infected individuals and play a direct role in the development of HIV-1-associated dementia (HAD). Therefore, investigation o