Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Abigail Ngoepe"'
Autor:
Khadija Khan, Gila Lustig, Farina Karim, Bernadett I Gosnell, Suzaan Marais, Prakash Jeena, Rohen Harrichandparsad, Anne Derache, Sandile Cele, Mahomed-Yunus S. Moosa, Ravindra K. Gupta, Katya Govender, Alex Sigal, Ntombi Ntshuba, Abigail Ngoepe, Vinod B. Patel, John H. Adamson, Henrik N. Kløverpris
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009871 (2021)
Lustig, G, Cele, S, Karim, F, Derache, A, Ngoepe, A, Khan, K, Gosnell, B I, Moosa, M Y S, Ntshuba, N, Marais, S, Jeena, P M, Govender, K, Adamson, J, Kløverpris, H, Gupta, R K, Harrichandparsad, R, Patel, V B & Sigal, A 2021, ' T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy ', PLOS Pathogens, vol. 17, no. 9, e1009871 . https://doi.org/10.1371/journal.ppat.1009871
PLoS Pathogens
Lustig, G, Cele, S, Karim, F, Derache, A, Ngoepe, A, Khan, K, Gosnell, B I, Moosa, M Y S, Ntshuba, N, Marais, S, Jeena, P M, Govender, K, Adamson, J, Kløverpris, H, Gupta, R K, Harrichandparsad, R, Patel, V B & Sigal, A 2021, ' T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy ', PLOS Pathogens, vol. 17, no. 9, e1009871 . https://doi.org/10.1371/journal.ppat.1009871
PLoS Pathogens
HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in CSF, occurs when HIV persists in the CNS despite antiretroviral therapy (ART). To determine the virus producing cell type and whether lowered CSF ART levels are
Autor:
Julia Roider, Abigail Ngoepe, Maximilian Muenchhoff, Emily Adland, Andreas Groll, Thumbi Ndung'u, Henrik Kløverpris, Philip Goulder, Alasdair Leslie
Publikováno v:
Frontiers in immunology
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Roider, J, Ngoepe, A, Muenchhoff, M, Adland, E, Groll, A, Ndung'u, T, Kløverpris, H, Goulder, P & Leslie, A 2019, ' Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children ', Frontiers in Immunology, vol. 10, no. FEB, 213 . https://doi.org/10.3389/fimmu.2019.00213
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Roider, J, Ngoepe, A, Muenchhoff, M, Adland, E, Groll, A, Ndung'u, T, Kløverpris, H, Goulder, P & Leslie, A 2019, ' Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children ', Frontiers in Immunology, vol. 10, no. FEB, 213 . https://doi.org/10.3389/fimmu.2019.00213
Pediatric slow progressors (PSP) are rare ART-naïve, HIV-infected children who maintain high CD4 T-cell counts and low immune activation despite persistently high viral loads. Using a well-defined cohort of PSP, we investigated the role of regulator
Autor:
Julia Roider, Takashi Maehara, Abigail Ngoepe, Duran Ramsuran, Maximilian Muenchhoff, Emily Adland, Toby Aicher, Samuel W. Kazer, Pieter Jooste, Farina Karim, Warren Kuhn, Alex K. Shalek, Thumbi Ndung'u, Lynn Morris, Penny L. Moore, Shiv Pillai, Henrik Kløverpris, Philip Goulder, Alasdair Leslie
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in immunology
Frontiers
Roider, J, Maehara, T, Ngoepe, A, Ramsuran, D, Muenchhoff, M, Adland, E, Aicher, T, Kazer, S W, Jooste, P, Karim, F, Kuhn, W, Shalek, A K, Ndung'u, T, Morris, L, Moore, P L, Pillai, S, Kløverpris, H, Goulder, P & Leslie, A 2018, ' High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults ', Frontiers in Immunology, vol. 9, 1975 . https://doi.org/10.3389/fimmu.2018.01975
Frontiers in immunology
Frontiers
Roider, J, Maehara, T, Ngoepe, A, Ramsuran, D, Muenchhoff, M, Adland, E, Aicher, T, Kazer, S W, Jooste, P, Karim, F, Kuhn, W, Shalek, A K, Ndung'u, T, Morris, L, Moore, P L, Pillai, S, Kløverpris, H, Goulder, P & Leslie, A 2018, ' High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults ', Frontiers in Immunology, vol. 9, 1975 . https://doi.org/10.3389/fimmu.2018.01975
Broadly neutralizing antibodies (bnAbs) against HIV-1 are an effective means of preventing transmission. To better understand the mechanisms by which HIV-specific bnAbs naturally develop, we investigated blood and lymphoid tissue in pediatric infecti