Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Philip J. Norris"'
Autor:
Jeffrey N. Martin, Toshiro Niki, Lishomwa C. Ndhlovu, Steven G. Deeks, Jason D. Barbour, Mary Margaret Byron, Philip J. Norris, Glen M. Chew, Marion C. Lanteri, Ravi Tandon, Persephone Borrow, Mitsuomi Hirashima
Publikováno v:
AIDS research and human retroviruses, vol 30, iss 7
Galectin-9 (Gal-9) is a β-galactosidase-binding lectin that promotes apoptosis, tissue inflammation, and T cell immune exhaustion, and alters HIV infection in part through engagement with the T cell immunoglobulin mucin domain-3 (Tim-3) receptor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038a01229a8f8a248d7e0ba060bc614b
https://doi.org/10.1089/aid.2014.0004
https://doi.org/10.1089/aid.2014.0004
Autor:
Torsten B. Neilands, Eric Delwart, Tzong-Hae Lee, Jeffrey M. Linnen, Colleen F. Kelley, Hiroyu Hatano, Rebecca Hoh, Philip J. Norris, Jeffrey N. Martin, Steven G. Deeks, Michael P. Busch, Peter W. Hunt
Publikováno v:
AIDS. 24:2535-2539
HAART can effectively reduce plasma HIV RNA levels to below the level of detection in most HIV-infected patients. The degree to which residual low-level viremia persists during HAART remains unclear.We identified 180 individuals (median duration of H
Autor:
Abdool Karim Salim, Eric Hunter, Elwyn Chomba, Hana Golding, Surender Khurana, Joseph Mulenga, Barton F. Haynes, Koleka Mlisana, Susan Park, Frederick Hecht, Isaac R. Rodriguez-Chavez, Joseph B. Margolick, George J. Nemo, Pretty Sasono, Philip J. Norris, Susan Allen, Michael P. Busch
Publikováno v:
Journal of Clinical Microbiology. 48:281-285
HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detect
Autor:
Bradford S. Wagner, Daniel Kaufmann, Eric S. Rosenberg, Marylyn M. Addo, Mathias Lichterfeld, Lisa A. Cosimi, Marcus Altfeld, Philip J. Norris, Paul M. Bailey, Bruce D. Walker, Mary N. Johnston, Alessandro Sette, John Sidney, Christian Brander, Nicole Frahm
Publikováno v:
Journal of Virology. 78:4463-4477
Increasing evidence suggests that human immunodeficiency virus type 1 (HIV-1)-specific CD4 T-cell responses contribute to effective immune control of HIV-1 infection. However, the breadths and specificities of these responses have not been defined. W
Autor:
Kristin M. O'Sullivan, Bruce D. Walker, Lisa A. Cosimi, Daniel Kaufmann, Philip J. Norris, Howell F. Moffett, Todd M. Allen, Eric S. Rosenberg, Christian Brander
Publikováno v:
AIDS Research and Human Retroviruses. 20:315-325
Despite growing evidence that HIV-1-specific CD4(+) T helper (Th) cells may play a role in the control of viremia, discrete Th cell epitopes remain poorly defined. Furthermore, it is not known whether Th cell responses generated using vaccines based
Autor:
Miroslaw K. Gorny, Walter J. Moretto, Peter Chien, Michael Tuen, Philip J. Norris, Silvia Ratto-Kim, Douglas F. Nixon, Gareth Jones, Catarina E. Hioe, Susan Zolla-Pazner
Publikováno v:
Journal of Virology. 75:10950-10957
Human immunodeficiency virus (HIV)-specific CD4 T-cell responses, particularly to the envelope glycoproteins of the virus, are weak or absent in most HIV-infected patients. Although these poor responses can be attributed simply to the destruction of
Autor:
Aashish R. Jha, Brigid S. Boland, Lishomwa C. Ndhlovu, Douglas F. Nixon, Michael G. Rosenberg, Joan M. Chapman, Moraima Pagan, Jennifer E. Snyder-Cappione, Philip J. Norris, Fabio E. Leal
Publikováno v:
AIDS. 22:990-992
IL-17 is proinflammatory cytokine secreted by a unique CD4+ T (Th17) cell subset and proposed to play a role in host defense. We hypothesized that Th17 cells are lost in HIV-1 infection. HIV-1-infected children with plasma viremia below 50 copies/ml
Autor:
Mohamed Abdel-Mohsen, Sheila M. Keating, Rebecca Hoh, Leonard Chavez, Michael L. Samuels, Xutao Deng, Ravi Tandon, Steven G. Deeks, Satish K. Pillai, Philip J. Norris, Glen M. Chew, Ali Danesh, Cecilia M. Shikuma, Marion C. Lanteri, Mitsuomi Hirashima, Toshiro Niki, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
PLoS pathogens, vol 12, iss 6
PLoS Pathogens, Vol 12, Iss 6, p e1005677 (2016)
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 6, p e1005677 (2016)
PLoS Pathogens
Identifying host immune determinants governing HIV transcription, latency and infectivity in vivo is critical to developing an HIV cure. Based on our recent finding that the host factor p21 regulates HIV transcription during antiretroviral therapy (A
Autor:
Jinyan Liu, Sheila M. Keating, Norman L. Letvin, Hui Li, Barton F. Haynes, Keith G. Mansfield, Dror Kolodkin-Gal, Dan H. Barouch, Angela Carville, Brandon F. Keele, Beatrice H. Hahn, George M. Shaw, Philip J. Norris, Georgia D. Tomaras
Publikováno v:
Journal of virology. 84(19)
Defining the earliest virologic events following human immunodeficiency virus type 1 (HIV-1) transmission may be critical for the design of vaccine strategies aimed at blocking acquisition of HIV-1 infection. In particular, the length of the eclipse
Autor:
Eric Delwart, Susan L. Stramer, Rebecca Hoh, Peter W. Hunt, Jeffrey M. Linnen, Hiroyu Hatano, Jeffrey N. Martin, Joseph M. McCune, Philip J. Norris, Tzong-Hae Lee, Michael P. Busch, Joan Dunn-Williams, Steven G. Deeks
Publikováno v:
Journal of virology. 83(1)
A subset of antiretroviral-untreated, human immunodeficiency virus (HIV)-infected individuals are able to maintain undetectable plasma HIV RNA levels in the absence of antiretroviral therapy. These “elite” controllers are of high interest as they