Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Philip J. Norris"'
Autor:
Kamonkiat Wirunsawanya, Bruce Shiramizu, Cecilia M. Shikuma, Philip J. Norris, Sheila M. Keating, Dominic C. Chow, Brooks I. Mitchell, Lindsay B Kohorn, Lishomwa C. Ndhlovu, Loni Belyea, Richard M. Watanabe, Scott A. Souza
Publikováno v:
AIDS Research and Human Retroviruses. 33:723-727
Plasminogen activator inhibitor type 1 (PAI-1), a key negative regulator of fibrinolysis, has been investigated to be one of the potential mechanisms of the development of impaired insulin sensitivity, insulin resistance, and diabetes mellitus. Becau
Publikováno v:
Cytokine & Growth Factor Reviews. 23:193-206
From early in the HIV epidemic it was appreciated that many inflammatory markers such as neopterin and TNF-α were elevated in patients with AIDS. With the advent of modern technology able to measure a broad array of cytokines, we now know that from
Autor:
Kathryn Anastos, Mardge H. Cohen, Alan L. Landay, Elizabeth T. Golub, Mary Young, Howard Crystal, Jinbing Zhang, Philip J. Norris, Ruth M. Greenblatt, Seema Desai, Marek Nowicki, Sheila M. Keating, Stephen J. Gange, Shiquan Wu
Publikováno v:
AIDS. 25:1823-1832
HIV causes inflammation that can be at least partially corrected by HAART. To determine the qualitative and quantitative nature of cytokine perturbation, we compared cytokine patterns in three HIV clinical groups, including HAART responders (HAART),
Autor:
Sandra M. Reynolds, Charles R. Rinaldo, Jay H. Bream, Persephone Borrow, Oliver Dibben, Joseph B. Margolick, Christopher Cox, Alan L. Landay, Elizabeth Sinclair, Candice B Mulder, Philip J. Norris, Elizabeth C. Breen, Lisa P. Jacobson, Larry Magpantay, Elise Sambrano, Otoniel Martinez-Maza
Publikováno v:
Clinical and Vaccine Immunology. 18:1229-1242
The concentrations of cytokines in human serum and plasma can provide valuable information about in vivo immune status, but low concentrations often require high-sensitivity assays to permit detection. The recent development of multiplex assays, whic
Autor:
John W. Heitman, Philip J. Norris, Hope H. Biswas, Jeffrey N. Martin, Steven G. Deeks, Melissa R. Krone, Rachel E. Owen, Marion C. Lanteri, Dale F. Hirschkorn
Publikováno v:
AIDS. 24:1095-1105
HIV elite controllers are a unique group of rare individuals who maintain undetectable viral loads in the absence of antiretroviral therapy. We studied immune responses in these individuals to inform vaccine development, with the goal of identifying
Autor:
Jeffery N Martin, Qi Xuan Tan, Rachel E. Owen, Frederick Hecht, Jeffery M. Harris, Mark A. Jacobson, John W. Heitman, Joseph M. McCune, Dale F. Hirschkorn, Brian Custer, Philip J. Norris, Elizabeth Sinclair, Steven G. Deeks, C. Lorrie Epling, Brinda Emu
Publikováno v:
Journal of Immunological Methods. 326:93-115
Although cryopreservation of peripheral blood mononuclear cells (PBMC) is a commonly used technique, the degree to which it affects subsequent functional studies has not been well defined. Here we demonstrate that long-term cryopreservation has detri
Autor:
Brandee L. Pappalardo, Gerald Spotts, Brian Custer, Frederick Hecht, Philip J. Norris, Michael P. Busch
Publikováno v:
AIDS Research and Human Retroviruses. 22:757-762
Perturbations of plasma IL-10, IL-12, IL-13, TNF-alpha, and IFN-gamma were measured longitudinally in HIV-1 seroconverting plasma donors and were compared to subjects with symptomatic primary HIV-1 infection. Control groups included uninfected patien
Autor:
Allan C. deCamp, John W. Heitman, E Haygreen, Philip J. Norris, Elizabeth Taylor, Steven G. Self, Persephone Borrow, Li Qin, Andrea Stacey, Dongfeng Li, Douglas I. Grove, Mila Lebedeva
Publikováno v:
Journal of Virology
Characterization of the immune responses induced in the initial stages of human immunodeficiency virus type 1 (HIV-1) infection is of critical importance for an understanding of early viral pathogenesis and prophylactic vaccine design. Here, we used
Autor:
M. Scott Killian, Bhupat D. Rawal, Philip J. Norris, Mila Lebedeva, Frederick Hecht, Jay A. Levy, Michael P. Busch
Publikováno v:
AIDS research and human retroviruses. 22(7)
HIV-specific antibodies become detectable and continue to increase in frequency during primary infection. The effects of early antiretroviral treatment (ART) and its discontinuation on the evolution of this immune response have not been systematicall
Autor:
Sheila M. Keating, Emilie Jalbert, Cecilia M. Shikuma, Nisha I. Parikh, Beau K. Nakamoto, Michelle L D'Antoni, Timothy Q. Crawford, Jason D. Barbour, Todd B. Seto, Philip J. Norris, Lishomwa C. Ndhlovu
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75500 (2013)
PLoS ONE
PLoS ONE
Chronic infection by HIV increases the risk of cardiovascular disease (CVD) despite effective antiretroviral therapy (ART). The mechanisms linking HIV to CVD have yet to be fully elucidated. High plasma levels of the pro-inflammatory cytokine IL-6, w