Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Edward O McFalls"'
Autor:
Rishav Aggarwal, Koray N. Potel, Annie Shao, Simon W. So, Cory Swingen, Christina P. Reyes, Rebecca Rose, Christin Wright, Laura L. Hocum Stone, Edward O. McFalls, Tammy A. Butterick, Rosemary F. Kelly
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5475 (2023)
Diastolic dysfunction persists despite coronary artery bypass graft surgery (CABG) in patients with hibernating myocardium (HIB). We studied whether the adjunctive use of a mesenchymal stem cells (MSCs) patch during CABG improves diastolic function b
Externí odkaz:
https://doaj.org/article/df8231e8a5ec4154b93682c3365ddb26
Publikováno v:
Nutrition & Metabolism, Vol 16, Iss 1, Pp 1-10 (2019)
Abstract Background Expression of mitochondrial proteins is reduced within hibernating myocardium (HM). It is unclear whether dietary supplementation with CoQ10 can increase expression of mitochondrial electron transport chain (ETC) and antioxidant p
Externí odkaz:
https://doaj.org/article/b05b179c53d24a35bec0a38038fd7599
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2155 (2022)
Ischemic heart disease affects millions of people around the world. Current treatment options, including coronary artery bypass grafting, do not result in full functional recovery, highlighting the need for novel adjunctive therapeutic approaches. Hi
Externí odkaz:
https://doaj.org/article/7746e8bae0e24f76a2e033d472e6d541
Publikováno v:
Nutrition & Metabolism, Vol 16, Iss 1, Pp 1-10 (2019)
Nutrition & Metabolism
Nutrition & Metabolism
Background Expression of mitochondrial proteins is reduced within hibernating myocardium (HM). It is unclear whether dietary supplementation with CoQ10 can increase expression of mitochondrial electron transport chain (ETC) and antioxidant proteins w
Autor:
Herbert B. Ward, Rosemary F. Kelly, Laura Hocum Stone, Christin Wright, Christopher T. Holley, Cory Swingen, Erin Chappuis, Edward O. McFalls
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 153:582-590
Objective Clinical studies demonstrate delayed recovery of hibernating myocardium (HM) following coronary artery bypass graft (CABG) surgery. Cardiac magnetic resonance (CMR) imaging is effective in identifying HM in clinical settings. Our animal mod
Autor:
Laura Hocum Stone, Maribel Marquez, Tammy A. Butterick, Erin Chappuis, Rosemary F. Kelly, Edward O. McFalls
Publikováno v:
Cell Medicine
Hibernating myocardium is a subset of ischemic cardiac disease characterized by viable but dysfunctional tissue. Standard treatment for hibernating myocardium is coronary artery bypass graft, which reduces arrhythmias and improves survival but does n
Autor:
Herbert B. Ward, Laura Hocum Stone, Christin Wright, Edward O. McFalls, Rosemary F. Kelly, Erin Chappuis, Mia Messer
Chronic cardiac ischemia that impairs cardiac function, but does not result in infarct, is termed hibernating myocardium (HM). A large clinical subset of coronary artery disease (CAD) patients have HM, which in addition to causing impaired function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d0a721c41d577cf537695b3ac61b84
https://europepmc.org/articles/PMC5933266/
https://europepmc.org/articles/PMC5933266/
Autor:
Tammy A. Butterick, Eric K. Long, Laura Hocum Stone, Edward O. McFalls, Rosemary F. Kelly, Christopher T. Holley, Megan E. Lindsey, Cayla M. Duffy
Publikováno v:
Journal of Surgical Research. 195:29-36
Hibernating myocardium is characterized by viable yet dysfunctional myocardium secondary to chronic ischemia, with studies demonstrating incomplete early recovery after coronary artery bypass graft (CABG). We tested whether mitochondrial fusion prote
Autor:
Megan E. Lindsey, Cayla M. Duffy, Herbert B. Ward, Christopher T. Holley, Jesus A Cabrera, Eric K. Long, Rosemary F. Kelly, Edward O. McFalls, Tammy A. Butterick
Publikováno v:
Journal of Surgical Research. 193:15-21
We have previously shown that mitochondrial uncoupling protein-2 (UCP-2) is increased in a swine model of hibernating myocardium (HM). Although UCP-2 reduces oxidant stress, it can promote inefficiency of the electron transport chain. In this study,
Autor:
Edward O. McFalls, E B S Megan Lindsey, Eric K. Long, Rosemary F. Kelly, Christopher T. Holley
Publikováno v:
Journal of Cardiac Surgery. 30:224-231
Myocardial responses to chronic ischemia represent a continuum of adaptations resulting, over time, in a stress-resistant phenotype. One such adaptation, hibernating myocardium (HM), has increased antioxidant capacity that protects against ischemia-i