Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hans H. Cheng"'
Publikováno v:
Genes
Genes, Vol 12, Iss 1630, p 1630 (2021)
Volume 12
Issue 10
Genes, Vol 12, Iss 1630, p 1630 (2021)
Volume 12
Issue 10
The avian α-herpesvirus known as Marek’s disease virus (MDV) linearly integrates its genomic DNA into host telomeres during infection. The resulting disease, Marek’s disease (MD), is characterized by virally-induced lymphomas with high mortality
Autor:
John R. Dunn, Andrea Doeschl-Wilson, Hans H. Cheng, Richard I. Bailey, Jody K. Mays, Osvaldo Anacleto, Margo Chase-Topping
Publikováno v:
Bailey, R, Cheng, H H, Chase-Topping, M, Mays, J, Anacleto, O, Dunn, J R & Wilson, A 2020, ' Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence ', PLoS Biology, vol. 18, no. 3, e3000619 . https://doi.org/10.1371/journal.pbio.3000619
PLoS Biology, Vol 18, Iss 3, p e3000619 (2020)
PLoS Biology
PLoS Biology, Vol 18, Iss 3, p e3000619 (2020)
PLoS Biology
Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This leakiness is concerning because it increases vaccination coverage required to prevent disease spread and can promote evo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be2d1194bf771a4626665de35d2cadd
Autor:
Masahiro Niikura, Sudawapee Umthong, Cari Hearn, Olga Agafitei, S.-H. Sheldon Tai, Hans H. Cheng, John R. Dunn
Publikováno v:
Virology. 503:103-113
Gallid herpesvirus 2 (Marek's disease virus, MDV) causes lymphoproliferative Marek's disease (MD), and is unique among alphaherpesviruses as the viral genome encodes an oncoprotein, Meq. To elucidate the temporal relationship between Meq expression a
Autor:
Janet E. Fulton, John R. Dunn, Venugopal Nair, Sanjay M. Reddy, Hans H. Cheng, Masahiro Niikura
Publikováno v:
Avian Diseases. 61:107-114
Marek's disease virus (MDV) is an alphaherpesvirus that causes Marek's disease (MD), a lymphoproliferative disease in chickens. Understanding of MDV gene function advanced significantly following the cloning of the MDV genome as either a series of ov
Publikováno v:
Vaccine. 34(46):5554-5561
Marek’s disease (MD) is a lymphotropic and oncogenic disease of chickens that can lead to death in susceptible and unvaccinated host birds. The causative pathogen, MD virus (MDV), a highly oncogenic alphaherpesvirus, integrates into host genome nea
Publikováno v:
The Journal of general virology. 100(7)
Marek’s disease virus (MDV) is the most well-cited example of vaccine-driven virulence evolution. MDV induces a lymphoproliferative disease in chickens, which is currently controlled by widespread vaccination of flocks. Unfortunately, Marek’s dis
Publikováno v:
Cytogenetic and Genome Research. 144:142-154
Marek's disease virus (MDV) is an oncogenic α-herpesvirus that induces Marek's disease characterized by fatal lymphomas in chickens. Here, we explored the timing during pathogenesis when the virus integrates into the host genome, the cell type invol
Publikováno v:
Journal of Virological Methods. 148:125-131
Marek's disease, a T cell lymphoma, is an economically important disease of poultry caused by the Marek's disease virus (MDV), a highly cell-associated alphaherpesvirus. A greater understanding of viral gene function and the contribution of sequence
Autor:
John R. Dunn, Alexis Black Pyrkosz, Sudeep Perumbakkam, Andres Legarra, Hans H. Cheng, William M. Muir
Publikováno v:
BMC Genomics
BMC Genomics, BioMed Central, 2015, 16 (1), pp.1-9. ⟨10.1186/s12864-015-2016-0⟩
BMC Genomics 1 (16), 1-9. (2015)
BMC Genomics, BioMed Central, 2015, 16 (1), pp.1-9. ⟨10.1186/s12864-015-2016-0⟩
BMC Genomics 1 (16), 1-9. (2015)
Background Marek’s disease (MD) is a lymphoproliferative disease of poultry induced by Marek’s disease virus (MDV), a highly oncogenic alphaherpesvirus. Identifying the underlying genes conferring MD genetic resistance is desired for more efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3393964013a7887bf574e60aa5ae817e
https://hal.inrae.fr/hal-02635208/file/2015_Cheng_BMCGenomics_1.pdf
https://hal.inrae.fr/hal-02635208/file/2015_Cheng_BMCGenomics_1.pdf
Publikováno v:
Archives of Virology. 151:1431-1438
The Marek's disease virus (MDV) genome contains 2 sets of 132-bp tandem repeat sequences. An increase in 132-bp repeat units has been associated with attenuation of oncogenicity during in vitro passage. By cloning entire genomes, we demonstrated that