Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Akihisa Kato"'
Publikováno v:
J Virol
We investigated whether A-type lamins (lamin A/C) and lamin B receptor (LBR) are redundant during herpes simplex virus 1 (HSV-1) infection in HeLa cells expressing lamin A/C and LBR. Lamin A/C and LBR double knockout (KO) in HSV-1-infected HeLa cells
Autor:
Kosuke Takeshima, Yasushi Kawaguchi, Takeharu Minamitani, Naoto Koyanagi, Teruhito Yasui, Masayuki Shimojima, Mizuki Watanabe, Yuhei Maruzuru, Isao Kosugi, Ayano Fukui, Masaaki Oyama, Hiroko Kozuka-Hata, Yuji Kubota, Jun Arii, Yasuko Mori, Akihisa Kato, Mutsuhiro Takekawa
Publikováno v:
J Virol
Viral cell-to-cell spread, a method employed by several viral families for entrance via cell junctions, is highly relevant to the pathogenesis of various viral infections. Cell-to-cell spread of herpes simplex virus 1 (HSV-1) is known to depend great
Autor:
Jun Arii, Akihisa Kato, Yuta Shimanaka, Yasushi Kawaguchi, Naoto Koyanagi, Yasuko Mori, Hiroyuki Arai, Ayano Fukui, Yuhei Maruzuru, Nozomu Kono
Publikováno v:
J Virol
Glycerophospholipids are major components of cell membranes. Phosphatidylethanolamine (PE) is a glycerophospholipid that is involved in multiple cellular processes, such as membrane fusion, the cell cycle, autophagy, and apoptosis. In this study, we
Publikováno v:
Journal of Virology. 90:10170-10181
Herpes simplex virus 1 (HSV-1) envelope glycoprotein D (gD) plays an essential role in viral entry. The functional regions of gD responsible for viral entry have been mapped to its extracellular domain, whereas the gD cytoplasmic domain plays no obvi
Publikováno v:
Journal of virology. 93(14)
During the nuclear export of nascent nucleocapsids of herpes simplex virus 1 (HSV-1), the nucleocapsids acquire a primary envelope by budding through the inner nuclear membrane into the perinuclear space between the inner and outer nuclear membranes.
Autor:
Akihisa Kato, Shinya Oda, Hiroko Kozuka-Hata, Jun Arii, Masaaki Oyama, Yasushi Kawaguchi, Naoto Koyanagi, Mizuki Watanabe, Yuhei Maruzuru
Publikováno v:
Journal of Virology. 92
Herpes simplex virus 1 (HSV-1) UL51 is a phosphoprotein that functions in the final envelopment in the cytoplasm and viral cell-cell spread, leading to efficient viral replication in cell cultures. To clarify the mechanism by which UL51 is regulated
Publikováno v:
Journal of Virology. 90:457-473
Us3 protein kinases encoded by herpes simplex virus 1 (HSV-1) and 2 (HSV-2) play important roles in viral replication and pathogenicity. To investigate type-specific differences between HSV-1 Us3 and HSV-2 Us3 in cells infected by viruses with all th
Autor:
Akihisa, Kato, Yasushi, Kawaguchi
Publikováno v:
Advances in experimental medicine and biology. 1045
All members of the Alphaherpesvirinae subfamily encode a serine/threonine kinase, designated Us3, which is not conserved in the other subfamilies. Us3 is a significant virulence factor for herpes simplex virus type 1 (HSV-1), which is one of the best
Autor:
Hiroshi Sagara, Hiroko Kozuka-Hata, Keiko Shindo, Zhuoming Liu, Yasushi Kawaguchi, Masaaki Oyama, Jun Arii, Akihisa Kato, Yoshitaka Hirohata
Publikováno v:
Journal of Virology. 89:7799-7812
Herpesviruses have evolved a unique mechanism for nucleocytoplasmic transport of nascent nucleocapsids: the nucleocapsids bud through the inner nuclear membrane (INM; primary envelopment), and the enveloped nucleocapsids then fuse with the outer nucl
Autor:
Jun Arii, Michio Mugitani, Yukie Kashima, Hiroko Kozuka-Hata, Masaaki Oyama, Akihisa Kato, Yasushi Kawaguchi, Hikaru Fujii
Publikováno v:
Journal of Virology. 88:10624-10634
The herpes simplex virus 1 (HSV-1) UL12 protein (pUL12) is a nuclease that is critical for viral replication in vitro and neurovirulence in vivo . In this study, mass spectrometric analysis of pUL12 and phosphate-affinity SDS-polyacrylamide gel elect