Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Connor G. G. Bamford"'
Autor:
Connor G G, Bamford, Elihu, Aranday-Cortes, Ricardo, Sanchez-Velazquez, Catrina, Mullan, Alain, Kohl, Arvind H, Patel, Sam J, Wilson, John, McLauchlan
Publikováno v:
Viruses. 14(8)
Natural hepatitis C virus (HCV) infection is restricted to humans, whereas other primates such as rhesus macaques are non-permissive for infection. To identify human and rhesus macaque genes that differ or share the ability to inhibit HCV replication
Autor:
Connor G. G. Bamford, John McLauchlan
Publikováno v:
Bamford, C G G & McLauchlan, J 2021, ' An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells ', Journal of General Virology, vol. 102, no. 2 . https://doi.org/10.1099/jgv.0.001495
Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV polypr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603ce0e357764cfa0e14271e50b55401
https://eprints.gla.ac.uk/222349/1/222349.pdf
https://eprints.gla.ac.uk/222349/1/222349.pdf
Autor:
Eleanor Barnes, Michelle Cheung, John McLauchlan, William L. Irving, Wing-Yiu Jason Lee, David A. Smith, M. Azim Ansari, Connor G. G. Bamford, Meleri Jones, Sampath DaSilva, Peter A.C. Wing, Elihu Aranday-Cortes, Graham R. Foster, Morven Cunningham, Ana da Silva Filipe
Publikováno v:
Gastroenterology
BACKGROUND & AIMS: Sofosbuvir is a frequently used pan-genotype inhibitor of hepatitis C virus (HCV) polymerase. This drug eliminates most chronic HCV infections and resistance-associated substitutions in the polymerase are rare. However, HCV genotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15381bbbe0a38344b99de9f3ac715c3a
https://ora.ox.ac.uk/objects/uuid:416feebd-d673-4614-9eb1-08d83c47f8f6
https://ora.ox.ac.uk/objects/uuid:416feebd-d673-4614-9eb1-08d83c47f8f6
Publikováno v:
The Journal of General Virology
Chronic infection of the liver by hepatitis C virus (HCV) induces a range of host factors including IFN-stimulated genes such as ISG15. ISG15 functions as an antiviral factor that limits virus replication. Previous studies have suggested that ISG15 c
Autor:
K. Christopher Garcia, Inès Cordeiro Filipe, Connor G. G. Bamford, Shaohua Fan, Daniel Mair, Ana da Silva Filipe, John McLauchlan, Juan L. Mendoza, Sarah A. Tishkoff, Swathi Sukumar, Elihu Aranday-Cortes
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 10, p e1007307 (2018)
PLoS Pathogens, Vol 14, Iss 10, p e1007307 (2018)
As antimicrobial signalling molecules, type III or lambda interferons (IFNλs) are critical for defence against infection by diverse pathogens, including bacteria, fungi and viruses. Counter-intuitively, expression of one member of the family, IFNλ4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8835735d373a1ae502d94033ea47b13d
https://doi.org/10.1101/214825
https://doi.org/10.1101/214825