Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Winfred C Wang"'
Autor:
Scott T. Miller, Rathi V. Iyer, Russell E. Ware, Zora R. Rogers, Bea Files, Barry L. Shulkin, John H. Miller, Eglal Shalaby-Rana, Winfred C. Wang, Bruce W. Thompson, Zhaoyu Luo, Peter A. Lane, Stephen D. Dertinger
Publikováno v:
Blood. 117:2614-2617
We evaluated spleen function in 193 children with sickle cell anemia 8 to 18 months of age by 99mTc sulfur-colloid liver-spleen scan and correlated results with clinical and laboratory parameters, including 2 splenic biomarkers: pitted cell counts (P
Autor:
Song Wu, Banu Aygun, Jennifer Parker, Molly Beth Freeman, Winfred C. Wang, Jane S. Hankins, Matthew P. Smeltzer, Alexis L. Stephens
Publikováno v:
Pediatric Blood & Cancer. 56:620-624
Background Neurocognitive deficits have been described in school age children with sickle cell disease (SCD), even in the absence of stroke or silent infarcts. However, the age of onset and factors contributing to this problem have not been well stud
Autor:
Tally Hustace, MaryLou MacDermott, Brenda Martin, Scott T. Miller, Zhaoyu Luo, Betsy Rackoff, Lea Adix, Billie Fish, Lynn W. Wynn, Phillip Seaman, Lane G. Faughnan, Tracy Kelly, Glenda Thomas, Caroline Reed, Jennifer McDuffie, Ellen Debenham, Joan Marasciulo, Mary A. Murphy, Winfred C. Wang
Publikováno v:
Contemporary Clinical Trials. 31:558-563
Background Protocol-eligible subjects may not be candidates for research participation or may decline. To determine factors that affected accrual, we evaluated enrollment in BABY HUG, a multi-center, randomized, placebo-controlled Phase III trial of
Autor:
William Schaffner, Natasha B. Halasa, Sadhna M. Shankar, Allen S. Craig, Patrick G. Arbogast, Marie R. Griffin, Winfred C. Wang, Ed Mitchel, Thomas R. Talbot
Publikováno v:
Clinical Infectious Diseases. 44:1428-1433
Background. We sought to determine the incidence of invasive pneumococcal disease (IPD) among individuals with sickle cell disease (SCD) before and after the introduction of the pneumococcal conjugate vaccine (PCV).Methods. Individuals with SCD who w
Autor:
Winfred C. Wang, Deepika Darbari, Samir K. Ballas, Meredith Milet, Nancy F. Olivieri, Kim Smith-Whitley, Paul Harmatz, Ellen B. Fung, Ward Hagar, William Owen, Elliott Vichinsky, Laura M. De Castro
Publikováno v:
American Journal of Hematology. 82:255-265
A natural history study was conducted in 142 Thalassemic (Thal), 199 transfused Sickle Cell Disease (Tx-SCD, n = 199), and 64 non-Tx-SCD subjects to describe the frequency of iron-related morbidity and mortality. Subjects recruited from 31 centers in
Autor:
Matthew M. Heeney, Martin H. Steinberg, Russell E. Ware, Hong-Yuan Luo, Shawn H. Eung, Winfred C. Wang, David H.K. Chui
Publikováno v:
American Journal of Hematology. 81:361-365
There are approximately 1200 known natural mutations of the human globin genes. In most clinical laboratories, the diagnosis of hemoglobin disorders is based on blood counts, hemoglobin electrophoresis, or column chromatography, which can identify co
Autor:
Winfred C. Wang, Donald Brambilla, Nancy F. Olivieri, Lori Styles, Knashawn H. Morales, Robert J. Adams, Charles D. Scher
Publikováno v:
The Journal of Pediatrics. 147:244-247
Objective To determine whether long-term transfusion improves growth in children with sickle cell anemia. Study design In the Stroke Prevention Trial for Sickle Cell Anemia Study, patients were randomized to receive long-term transfusion (CTX) or sta
Autor:
Robert J. Adams, Abdullah Kutlar, Suzanne Granger, Winfred C. Wang, Beatrice Files, Scott T. Miller, Donald Brambilla, Elliott Vichinsky
Publikováno v:
Journal of Pediatric Hematology/Oncology. 24:284-290
Purpose Chronic red cell transfusion has been used for prevention of recurrent stroke in patients with sickle cell disease for three decades, and its effectiveness in primary prevention was recently shown. Iron overload, the inevitable result of chro
Autor:
Rupa Redding-Lallinger, Kwaku Ohene-Frempong, Lori Styles, Henry Lynn, Myron A. Waclawiw, Beatrice E. Gee, Ronald W. Helms, Elliott Vichinsky, Russell E. Ware, Kim Smith-Whitley, Winfred C. Wang, Thomas R. Kinney
Publikováno v:
The Journal of Pediatrics. 140:225-229
Objectives: Although hydroxyurea is effective in treating adults with sickle-cell anemia (SCA), there is concern that it may adversely affect growth in children. We report the growth characteristics of patients in the Phase I-II pediatric hydroxyurea
Autor:
Charles Daeschner, Russell E. Ware, Barry Eggleston, Lori Styles, Kim Smith-Whitley, Thomas R. Kinney, Rupa Redding-Lallinger, Winfred C. Wang, Ronald W. Helms, Beatrice E. Gee, Kwaku Ohene-Frempong
Publikováno v:
Blood. 99:10-14
In the phase I/II pediatric hydroxyurea safety trial (HUG-KIDS), school-aged children with sickle cell anemia receiving hydroxyurea at the maximally tolerated dose (MTD) had variable increases in the percentage of fetal hemoglobin (%HbF). To identify