Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Winfred C Wang"'
Autor:
Tally Hustace, MaryLou MacDermott, Brenda Martin, Scott T. Miller, Zhaoyu Luo, Betsy Rackoff, Lea Adix, Billie Fish, Lynn W. Wynn, Phillip Seaman, Lane G. Faughnan, Tracy Kelly, Glenda Thomas, Caroline Reed, Jennifer McDuffie, Ellen Debenham, Joan Marasciulo, Mary A. Murphy, Winfred C. Wang
Publikováno v:
Contemporary Clinical Trials. 31:558-563
Background Protocol-eligible subjects may not be candidates for research participation or may decline. To determine factors that affected accrual, we evaluated enrollment in BABY HUG, a multi-center, randomized, placebo-controlled Phase III trial of
Autor:
William Schaffner, Natasha B. Halasa, Sadhna M. Shankar, Allen S. Craig, Patrick G. Arbogast, Marie R. Griffin, Winfred C. Wang, Ed Mitchel, Thomas R. Talbot
Publikováno v:
Clinical Infectious Diseases. 44:1428-1433
Background. We sought to determine the incidence of invasive pneumococcal disease (IPD) among individuals with sickle cell disease (SCD) before and after the introduction of the pneumococcal conjugate vaccine (PCV).Methods. Individuals with SCD who w
Autor:
Rupa Redding-Lallinger, Kwaku Ohene-Frempong, Lori Styles, Henry Lynn, Myron A. Waclawiw, Beatrice E. Gee, Ronald W. Helms, Elliott Vichinsky, Russell E. Ware, Kim Smith-Whitley, Winfred C. Wang, Thomas R. Kinney
Publikováno v:
The Journal of Pediatrics. 140:225-229
Objectives: Although hydroxyurea is effective in treating adults with sickle-cell anemia (SCA), there is concern that it may adversely affect growth in children. We report the growth characteristics of patients in the Phase I-II pediatric hydroxyurea
Autor:
Charles Daeschner, Russell E. Ware, Barry Eggleston, Lori Styles, Kim Smith-Whitley, Thomas R. Kinney, Rupa Redding-Lallinger, Winfred C. Wang, Ronald W. Helms, Beatrice E. Gee, Kwaku Ohene-Frempong
Publikováno v:
Blood. 99:10-14
In the phase I/II pediatric hydroxyurea safety trial (HUG-KIDS), school-aged children with sickle cell anemia receiving hydroxyurea at the maximally tolerated dose (MTD) had variable increases in the percentage of fetal hemoglobin (%HbF). To identify
Publikováno v:
The Journal of Pediatrics. 139:790-796
Objective: Hydroxyurea improves hematologic values and decreases vaso-occlusive complications in adults and children with sickle cell anemia (SCA), but has not been tested in infants before the onset of chronic organ dysfunction. We conducted a colla
Publikováno v:
Journal of Pediatric Hematology/Oncology. 23:112-116
Prophylactic penicillin is effective in preventing severe invasive pneumococcal infection in children with sickle cell disease. In some families, compliance has been problematic. The aims of this study were to monitor compliance and to assess the eff
Autor:
Zora R. Rogers, Charles H. Pegelow, Clarice D. Reid, James H. Jorgensen, Michael R. DeBaun, C. Tate Holbrook, Neil J. Grossman, John M. Falletta, Marilyn D. Thomas, Winfred C. Wang, Rathi V. Iyer, Myron A. Waclawiw, Thomas R. Kinney, Gerald M. Woods, Elliott Vichinsky
Publikováno v:
Journal of Pediatric Hematology/Oncology. 19:327-333
PURPOSE To evaluate the consequences of prolonged prophylactic penicillin use on the rates of nasopharyngeal colonization with Streptococcus pneumoniae and the prevalence of resistant pneumococcal strains in children with sickle cell anemia. METHODS
Autor:
Winfred C. Wang, Gregory H. Reaman, Karen Kalinyak, Clarice D. Reid, Elliott Vichinsky, David L. Becton, Rathi V. Iyer, George R. Buchanan, Gerald M. Woods, John M. Falletta, Michael R. DeBaun, Helen S. Johnstone, C. Tate Holbrook, Charles H. Pegelow, Thomas R. Kinney, Neil J. Grossman, Ann B. Bjornson, Marilyn D. Thomas, Doris L. Wethers, Scott T. Miller, Joel Verter, James H. Jorgensen
Publikováno v:
The Journal of Pediatrics. 127:685-690
Objective : To evaluate the consequences of discontinuing penicillin prophylaxis at 5 years of age in children with sickle cell anemia who had received prophylactic penicillin for much of their lives. Design : Randomized, double-blind, placebo-contro
Autor:
Martha Rieman, Graham R. Serjeant, Jesse J. Jenkins, Winfred C. Wang, Paula Naidu, Michael Jeng, Sue C. Kaste
Publikováno v:
Journal of pediatric hematology/oncology. 25(3)
Hepatic sequestration is an uncommon complication in patients with homozygous sickle cell disease. Although transfusion therapy has been effective for the acute condition, no definitive treatment of chronic hepatic sequestration has been identified.
Publikováno v:
The Journal of pediatrics. 140(5)
Objective: To obtain quantitative serum levels of total and ionized magnesium (Mg 2+ ) in children with homozygous sickle cell anemia (SCA) undergoing therapy with hydroxyurea. Study design: Five children, ages 11 to 14 years with homozygous SCA, wer