Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kevin J. Curran"'
Autor:
Andromachi Scaradavou, Richard J. O'Reilly, Jaap Jan Boelens, Farid Boulad, Susan E. Prockop, Barbara Spitzer, Ichelle van Roessel, Andrew L. Kung, Maria Cancio, Kevin J. Curran, Nancy A. Kernan, Elizabeth Klein
Publikováno v:
Cytotherapy
An association between early CD4+ T cell immune reconstitution (CD4+ IR) and survival after T-replete allogeneic hematopoietic cell transplantation (HCT) has been previously reported. Here we report validation of this relationship in a separate cohor
Autor:
Audrey Mauguen, Brian C. Shaffer, Ichelle van Roessel, Richard J. O'Reilly, Michael Scordo, Nancy A. Kernan, Christina Cho, Andrew L. Kung, Andromachi Scaradavou, Maria Cancio, Sergio Giralt, Miguel-Angel Perales, Barbara Spitzer, Kevin J. Curran, Madhavi Lakkaraja, Esperanza B. Papadopoulos, Elizabeth Klein, Sean M. Devlin, Farid Boulad, Susan E. Prockop, Ann A. Jakubowski, Gunjan L. Shah, Roni Tamari, Jaap Jan Boelens, Scott Avecilla, Josel D. Ruiz
Publikováno v:
Blood advances. 6(3)
Traditional weight-based dosing results in variable rabbit antithymocyte globulin (rATG) clearance that can delay CD4+ T-cell immune reconstitution (CD4+ IR) leading to higher mortality. In a retrospective pharmacokinetic/pharmacodynamic (PK/PD) anal
Autor:
Andromachi Scaradavou, Maria Cancio, Celina L. Szanto, Mirjam E. Belderbos, Elizabeth Klein, Wouter J.W. Kollen, Farid Boulad, Nancy A. Kernan, Dorine Bresters, Marc Bierings, Stefan Nierkens, Kevin J. Curran, Barbara Spitzer, Coco de Koning, Jurgen Langenhorst, Jaap Jan Boelens, Birgitta Versluijs, Caroline A. Lindemans, Susan E. Prockop, Alwin D. R. Huitema, Ichelle van Roessel, Richard J. O'Reilly
Publikováno v:
Blood
Acute graft-versus-host-Disease (aGVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). We previously showed that early CD4+ T-cell immune reconstitution (IR; CD4+ IR) predicts survival after HCT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5555c041f4a96722046831f6ef4a6558
https://europepmc.org/articles/PMC7986048/
https://europepmc.org/articles/PMC7986048/
Autor:
Andromachi Scaradavou, Meghan A. Higman, Barbara Spitzer, Jennifer Allen, Nicholas D. Yeager, Audrey Mauguen, Nancy A. Kernan, Elliot Stieglitz, Maria Cancio, Farid Boulad, Niketa C. Shah, Kevin J Curran, Vanessa A Fabrizio, Susan E. Prockop, Steven P. Margossian, Richard J. O'Reilly, Renier J. Brentjens, Jaap Jan Boelens
Publikováno v:
Bone marrow transplantation, vol 55, iss 11
Bone marrow transplantation
Bone marrow transplantation
To define the tolerability and outcome of allogeneic hematopoietic stem cell transplant (allo-HSCT) following CAR T-cell therapy, we retrospectively reviewed pediatric/young adult patients with relapsed/refractory B-ALL who underwent this treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cde197e69454cd2acee0da2cb995dc
https://escholarship.org/uc/item/9sv0d1wj
https://escholarship.org/uc/item/9sv0d1wj
Autor:
Maria Cancio, Andrew L. Kung, Alexandra M. Satty, Andromachi Scaradavou, Susan E. Prockop, Farid Boulad, Richard J. O’Reilly, Jaap Jan Boelens, Kevin J Curran, Elizabeth Klein, Barbara Spitzer, Nancy A. Kernan, Audrey Mauguen
Publikováno v:
Transplantation and Cellular Therapy. 27:S425-S426
Autor:
Rachel Lehrman, Kevin J. Curran, Richard J. O'Reilly, Julianne Ruggiero, Nancy A. Kernan, Farid Boulad, Rachel Kobos, Andromachi Scaradavou, Susan E. Prockop, Alberto Mussetti
Publikováno v:
Pediatric Hematology and Oncology. 33:347-358
Nonmalignant hematologic disorders (NMHD) of childhood comprise a variety of disorders, including acquired severe aplastic anemia and inherited marrow failure syndromes. Patients with high-risk NMHD without matched related donors fare poorly with all
Autor:
Mercedes Castiel, Richard J. O'Reilly, Nicole Zakak, Praveen Anur, Andromachi Scaradavou, Bhuvanesh Singh, Charles A. Sklar, Julia Kearney, Kevin C. Oeffinger, Danielle Novetsky Friedman, Rachel Kobos, Susan E. Prockop, Farid Boulad, Julianne Ruggiero, Nancy A. Kernan, Kevin J. Curran
Publikováno v:
Bone marrow transplantation
Hematopoietic stem cell transplantation (HSCT) is curative for hematological manifestations of Fanconi anemia (FA). We performed a retrospective analysis of 22 patients with FA and aplastic anemia, myelodysplastic syndrome or acute myelogenous leukem
Autor:
Ahmet Dogan, Carlos Fernández de Larrea, Oscar B Lahoud, Neha Korde, Kevin J. Curran, Brigitte Senechal, Craig S. Sauter, Nikoletta Lendvai, Pallavi Khattar, Achim A. Jungbluth, Analisa Wills, Mikhail Roshal, Ola Landgren, David J. Chung, Malin Hultcrantz, Maria Lia Palomba, Qi Gao, Claudia Diamonte, Renier J. Brentjens, Michael Scordo, Alexander M. Lesokhin, John Pineda, Sham Mailankody, Terence J. Purdon, Hani Hassoun, Sergio Giralt, Elizabeth Halton, Isabelle Riviere, Gunjan L. Shah, Xiuyan Wang, Jae H. Park, Pavan Anant, Arnab Ghosh, Heather Landau, Eric L. Smith, Mette Staehr, Yvette Bernal
Publikováno v:
Blood. 132:959-959
Introduction: BCMA targeted CAR T cell therapy has shown promising results in patients with relapsed/refractory multiple myeloma (MM). Herein, we report on the safety and efficacy of MCARH171, a second generation, human derived BCMA targeted autologo
Autor:
Hugo Castro-Malaspina, Rachel Kobos, Donna DiMichele, Farid Boulad, Andromachi Scaradavou, David J. Araten, Susan E. Prockop, Nancy A. Kernan, Kevin J. Curran, Richard J. O'Reilly, Trudy N. Small
Publikováno v:
Pediatric Blood & Cancer. 59:525-529
Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease in children. The most significant clinical features of PNH include: bone marrow failure, intravascular hemolysis, and thrombosis. To further characterize the clinical presentation
Autor:
Jeffrey S. Ross, Farid Boulad, Sohail Balasubramanian, Rachel Kobos, Elli Papaemmanuil, Scott A. Armstrong, Lu Wang, Alex Kentsis, Peter G. Steinherz, Neerav Shukla, Thomas M. Renaud, Ahmet Dogan, Vincent A. Miller, Shan Zhong, Christopher J. Forlenza, Michelle Nahas, Jo-Anne Vergilio, Phil Stephens, Jie He, Mikhail Roshal, Susan E. Prockop, Kristina M. Knapp, Ross L. Levine, Kevin J. Curran, Michael Walsh, Tariq I Mughal
Publikováno v:
Blood. 128:1605-1605
Subsets of pediatric acute leukemias are refractory to frontline therapy or relapse with standard treatment. Pediatric leukemias are associated with distinct molecular and genomic alterations. Clinical genomic profiling has been used effectively to i