Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Linda Rabin"'
Publikováno v:
Immunological Reviews. 124:45-62
Work in the SCID-hu system has progressed significantly over the past 3-4 years. Reliable SCID-hu constructs can now be created for the evaluation of long-term multilineage human hematopoiesis, human immune function, and HIV infection of human hemato
Autor:
Reiko Namikawa, Miriam Lieberman, Linda Rabin, Joseph M. McCune, J F Krowka, Bruno Péault, EJ Yee, C.-C. Shih, Hideto Kaneshima, Henry Outzen
Publikováno v:
Annual Review of Immunology. 9:399-429
The SCID-hu mouse is a heterochimeric small animal model designed to support hematopoietic differentiation and function in vivo. Multiple organs of the human hematolymphoid system have been successfully engrafted into the immunodeficient C.B-17 scid
Autor:
Joseph M. McCune, B. Chen, Reiko Namikawa, Charles M. Baum, Linda Rabin, Henry Outzen, A. Tsukamoto, Hideto Kaneshima
Publikováno v:
Nature. 348:561-562
Use of the SCID-hu mouse — an immunodeficient mouse transplanted with relevant organs of the human immune system — as a preclinical testing system for human therapeutics is discussed.