Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Cathy S. Wang"'
Autor:
Ning Xu, Erin Yu, Nicole Ng, Mingjie Li, Sean Bujarski, Ava Hekmati, Isabella Nassir, Tara Hekmati, Janna Yu, David Daniely, Cathy S. Wang, Clara Kim, Haiming Chen, James R. Berenson
Publikováno v:
Hematological oncologyREFERENCES.
We hypothesized that ruxolitinib may inhibit the immune checkpoint protein, B7H3; and, thus, investigated its effects on this immune inhibitor using multiple myeloma (MM) cell lines, bone marrow (BM) mononuclear cells from MM patients and human MM LA
Autor:
George Tang, Eric Sanchez, James R. Berenson, Abigail Gillespie, Cathy S Wang, Mingjie Li, Haiming Chen
Publikováno v:
Leukemia Research. 57:45-54
Oprozomib (OPZ or ONYX 0912) is an irreversible, orally administered proteasome inhibitor (PI) and an analog of carfilzomib. We set out to determine the anti-angiogenic effect of OPZ using the choriollantoic membrane/feather bud (CAM/FB) model and it
Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients
Autor:
Michael Ghermezi, Suzie Vardanyan, Claudia Andreu-Vieyra, Sophia Petraki, Kyle Udd, Cathy S Wang, Regina A. Swift, Tanya M. Spektor, Nika M Harutyunyan, Mingjie Li, Eric Sanchez, Jillian Gottlieb, James R. Berenson, Ariana Berenson, Haiming Chen
Publikováno v:
Haematologica
B-cell maturation antigen is expressed on plasma cells. In this study, we have identified serum B-cell maturation antigen as a novel biomarker that can monitor and predict outcomes for multiple myeloma patients. Compared to healthy donors, patients w
Autor:
Eric Sanchez, James R. Berenson, Aleksandra Vidisheva, Mingjie Li, George Tang, Tara Hekmati, Gabriel N. Waterman, Cathy S Wang, Camilia Soof, Saurabh Patil, Edward J Tanenbaum, Haiming Chen
Publikováno v:
Expert review of molecular diagnostics. 18(4)
B-cell maturation antigen (BCMA) is a cell membrane bound tumor necrosis factor receptor family member that is expressed exclusively on late stage normal and malignant B-cells and plasma cells. Addition of two of its ligands, B-cell activating factor
Autor:
Brian Zahab, Haiming Chen, Nicole Ng, Sean Bujarski, Cathy S Wang, Edward J Tanenbaum, George Tang, Ning Xu, Jasmin Cao, Tara Hekmati, Eric Sanchez, James R. Berenson, Mingjie Li, Camilia Soof
Publikováno v:
Blood. 132:1910-1910
Introduction: Ruxolitinib (RUX) is an inhibitor of the Janus kinase family of protein tyrosine kinases (JAKs) that is effective for the treatment of myeloproliferative diseases. Immunomodulatory drugs including lenalidomide (LEN) and corticosteroids
Autor:
Saurabh Patil, Eric Sanchez, James R. Berenson, Camilia Soof, Regina A. Swift, Kian J. Rahbari, Haiming Chen, Marsiye Emamy-Sadr, Sean Bujarski, Cathy S Wang, Tanya M. Spektor, Mingjie Li
Publikováno v:
Blood. 132:1894-1894
Background: B-cell maturation antigen (BCMA) is highly expressed on malignant plasma cells from patients with multiple myeloma (MM). We have previously shown that serum (s) BCMA levels are elevated among MM patients, and baseline levels predict both
Autor:
George Tang, Cathy S Wang, Mingjie Li, Eric Sanchez, James R. Berenson, Haiming Chen, Puja K. Mehta
Publikováno v:
Blood. 128:3297-3297
Introduction: Several studies have demonstrated constitutive activation of the JAK-STAT pathway in MM through dysregulated signaling of cytokines such as IL-6. In addition to its crucial role in promoting the growth, proliferation and survival of mye
Autor:
Kyle Udd, Zachary Gross, Eric Sanchez, Mingjie Li, James R. Berenson, Soudabeh Etessami, James Wang, Matthew Ghermezi, Cathy S Wang, Camilia Soof, Haiming Chen, Regina A. Swift, Marsiye Emamy-Sadr, Christian E. Casas
Publikováno v:
Blood. 128:5654-5654
Introduction: B-cell maturation antigen (BCMA) is a protein found on the surface of malignant plasma cells from multiple myeloma (MM) patients (pts). We have previously shown that MM pts show higher serum (s) levels of BCMA than healthy subjects and
Autor:
Tanya M. Spektor, Mingjie Li, Kyle Udd, Cathy S Wang, Zachary Gross, Camilia Soof, George Tang, Eric Sanchez, James R. Berenson, Matthew Ghermezi, Soudabeh Etessami, Regina A. Swift, Christian E. Casas, Haiming Chen
Publikováno v:
Blood. 128:5652-5652
Introduction: CD147 is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily. CD147 gene expression levels are elevated in several types of human cancer. Recent studies show that expression of CD147 is increased in multiple myel
Autor:
Kyle Udd, George Tang, Christian E. Casas, Cathy S Wang, Kevin DeCorso, Jessica Wang, Mingjie Li, Jasmin Cao, Tara Hekmati, Eric Sanchez, James R. Berenson, Camilia Soof, Haiming Chen
Publikováno v:
Blood. 128:5641-5641
Introduction: B-cell maturation antigen (BCMA) has been shown to be highly expressed on the surface of tumor cells from patients (pts) with multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) and is the target for therapeutic approaches in t