Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David Lyden"'
Autor:
E. Popa, David Lyden, Sorin Alexandrescu, N.I. Luca, Doru Paul, V.M. Croitoru, I. Sandra, Irina M. Cazacu, I-M. Gramaticu, Andrei Sorop, Irina Matei, Mircea Diculescu, Adina Croitoru, Simona Dima, C. Gheorghe, D. Bogdan, I.M. Dinu, Vlad Herlea, Irinel Popescu
Publikováno v:
Annals of Oncology. 32:S1371
Autor:
Mario E. Lacouture, Eli L. Diamond, Benjamin H. Durham, Ryma Benayed, Pallavi Khattar, David Lyden, Ira J. Dunkel, Omar Abdel-Wahab, Ehud Lavi, Neerav Shukla, Sara Zarnegar
Publikováno v:
Pediatric Blood & Cancer. 65
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasm characterized by constitutive activation of extracellular signal-regulated kinase (ERK). Genomic characterization has identified activating point mutations including mutually exc
Publikováno v:
Journal of Thrombosis and Haemostasis. 10:177-188
Dynamic interactions between haematopoietic cells and their specialised bone marrow microenvironments, namely the vascular and osteoblastic ‘niches’ regulate haematopoiesis. The vascular niche is conducive for thrombopoiesis, and megakaryocytes m
Autor:
Rosandra N. Kaplan, Oluwa T. Fabiyi, Donna DiMichele, Daniel D. MacDonald, Suchitra S. Acharya, David Lyden
Publikováno v:
Blood. 117:2484-2493
Joint arthropathy secondary to recurrent hemarthroses remains a debilitating complication of hemophilia despite the use of prophylactic factor concentrates. Increased vascularity and neoangiogenesis have been implicated in the progression of musculos
Autor:
Tibor Keler, Henry C. Marsh, David Lyden, Noreen Buckley, Niroshana Anandasabapathy, Gaëlle Breton, Maggi Pack, Marina Caskey, Thomas Hawthorne, Popi Sarma, Sarah J. Schlesinger, Michael Yellin, Christine Trumpfheller, Arlene Hurley, Jennifer Green, Irina Matei, Thomas P. Davis, James Pring
Fms-like tyrosine kinase-3 ligand (Flt3L) uniquely binds the Flt3 (CD135) receptor expressed on hematopoietic stem cells (HSCs), early progenitor cells, immature thymocytes and steady-state dendritic cells (DCs) and induces their proliferation, diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906c2eeabd03d7bedbc3f41deb751f76
https://europepmc.org/articles/PMC4532305/
https://europepmc.org/articles/PMC4532305/
Autor:
Stephen Gilheeney, Jason T. Huse, Shakeel Modak, Jill M. Kolesar, David Lyden, Ira J. Dunkel, Kim Kramer, Ivan Spasojevic, Oren J. Becher, Kevin C. De Braganca, Yasmin Khakoo, Sofia Haque, Leonard H. Wexler
Publikováno v:
Pediatric Blood & Cancer. 64:e26409
Background The PI3K/AKT/mTOR pathway is aberrantly activated in many pediatric solid tumors including gliomas and medulloblastomas. Preclinical data in a pediatric glioma model demonstrated that the combination of perifosine (AKT inhibitor) and temsi
Autor:
Nuno Lobo Antunes, William L. Gerald, Tanya M. Trippett, Kim Kramer, David Lyden, Nancy Rosen, Paul A. Meyers, Stephen Gilheeney, Leonard H. Wexler, Shirley C. Sgouros, Ira J. Dunkel, Eric Lis, Howard T. Thaler
Publikováno v:
Pediatric bloodcancer. 49(3)
Background Previous clinical and pre-clinical research has demonstrated synergy between anti-angiogenic agents and cytotoxic chemotherapy. This trial was undertaken to investigate whether the combination of cyclophosphamide and thalidomide would be a
Publikováno v:
Journal of Pediatric Hematology/Oncology. 28:700
Autor:
David Lyden, Daniel A. Greninger, Suchitra S. Acharya, Daniel D. MacDonald, Ilene Goldberg, Donna DiMichele, Margaret W. Hilgartner
Publikováno v:
Blood. 104:42-42
Hemarthrosis, or bleeding into a joint, is the most common manifestation of hemophilia. Recurrent hemarthroses and synovial proliferation leads to the formation of a thickened synovial pannus, or synovitis, followed by destructive infiltration into t
Autor:
Scott T. Avecilla, Joseph Cheng, David Lyden, Sergey V. Shmelkov, Lin Jun, Fan Zhang, Agata Calderone, Shahin Rafii, Kathryn A. Walsh, Gal Akiri, Matthias A. Karajannis, George Lam, Loic Vincent, Ryan St Clair, Rafael Tejada, Lauren M. Young, Hans-Georg Kopp, Kristian Jensen, Koji Shido, David K. Jin
Publikováno v:
Blood. 104:2002-2002
AC133 (CD133, human Prominin-1) is a cell-surface glycoprotein which is expressed on several types of stem cells, including hematopoietic stem cells and endothelial progenitor cells. AC133 is also expressed on acute and chronic myeloid leukemias, as