Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yong J. Lee"'
Autor:
Yong Tae Kwon, Dae Hee Lee, David L. Bartlett, Yoshiro Saito, Xinxin Song, Daeho Kim, Bo Yeon Kim, Sang Mi Shim, Jung Lim Kim, Sung Tae Kim, Sang Cheul Oh, Zong Sheng Guo, Ah Jung Heo, Soyeon Jeong, Yong J. Lee, Junho Lee
Publikováno v:
Autophagy. 14(11)
Macroautophagy is induced under various stresses to remove cytotoxic materials, including misfolded proteins and their aggregates. These protein cargoes are collected by specific autophagic receptors such as SQSTM1/p62 (sequestosome 1) and delivered
Publikováno v:
Cell Death & Differentiation. 9:448-456
We previously reported that overexpression of HSP25 delayed cell growth, increased the level of p21(waf), reduced the levels of cyclin D1, cyclin A and cdc2, and induced radioresistance in L929 cells. In this study, we demonstrated that HSP25 induced
Autor:
Christine M. Berns, Eliezer Huberman, Robert V. Blackburn, Peter M. Corry, Sandra Galoforo, Yong J. Lee
Publikováno v:
Biochemical Pharmacology. 52:311-319
We investigated the effect of 1α-25-dihydroxyvitamin D 3 [1,25-(OH) 2 D 3 ] on the expression of the 28-kDa heat shock protein gene ( hsp28 ) and the protein kinase C beta gene ( PKC β) in the human myeloid HL-60 leukemic cell variant HL-525, which
Autor:
Peter M. Corry, Yong J. Lee, Sandra Galoforo, Robert V. Blackburn, Joong M. Cho, Christine M. Berns, Mark E. Ireland
Publikováno v:
Molecular and Cellular Biochemistry. 155:51-60
We investigated the role of alpha B-crystallin expression in the development of thermotolerance in murine L929 cells. An initial heat-shock of 10 min at 45 degrees C induced thermotolerance in these cells to a heat challenge at 45 degrees C administe
Publikováno v:
Biochemical and Biophysical Research Communications. 199:714-719
The possible involvement of PKC in the regulation of heat shock genes expression was investigated with three isoquinolinesulfonamide derivatives (H-7, H-8, and HA1004) in DUT-145, MCF-7, and MCF-7/ADR cells. The drug was added 1 hr before and during
Publikováno v:
Journal of Cellular Physiology. 153:353-361
The constitutive HSP70 purified from CHO cells, which indicated a single band in SDS-polyacrylamide gel electrophoresis, showed multiple bands in native-polyacrylamide gel electrophoresis. These results indicate that the protein may exist in oligomer
Publikováno v:
Biochemical and Biophysical Research Communications. 186:1121-1128
When cells were heated for 15 min at 45 degrees C, they became thermotolerant to a second heat exposure at 45 degrees C. Thermotolerance developed rapidly, reached its maximum 6 hr after heat shock, and then gradually decayed. The development of ther
Publikováno v:
Journal of Cellular Physiology. 150:441-446
We investigated a correlation between development of thermotolerance and expression, synthesis, or phosphorylation of HSP28 family in CHO plateau phase cells. After heating at 45.5 degrees C for 10 min, thermotolerance developed rapidly and reached i
Publikováno v:
Biochemical and Biophysical Research Communications. 172:119-125
We observed that members of two HSP families (70 and 28 kDa) preferentially redistributed into the nucleus after heating at 45.5 degrees C for 10 min. The rates of synthesis and redistribution of these proteins were different for each member of HSP f
Publikováno v:
Journal of Cellular Physiology. 144:401-407
The possible mechanism for heat protection by the protein synthesis inhibitor histidinol was investigated in CHO cells. Histidinol (HST, 5 mM), an analogue of the essential amino acid L-histidine, added for 2 hr before and during heating at 43 degree