Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kritton Shay-Winkler"'
Autor:
Jeffrey Robbins, Katherine E. Yutzey, James Gulick, Yang Yu, Na Xu, Hanna Osinska, Kritton Shay-Winkler, Patrick M. McLendon
Publikováno v:
Circ Res
Rationale: Compromised protein quality control can result in proteotoxic intracellular protein aggregates in the heart, leading to cardiac disease and heart failure. Defining the participants and understanding the underlying mechanisms of cardiac pro
Autor:
Keri Anne Drake, Prasad Devarajan, Brian J. Siroky, Kritton Shay-Winkler, Priyanka Parameswaran, LaTawnya Pleasant, Qing Ma, Jeffrey Robbins, Mahima Devarajan
Publikováno v:
American Journal of Physiology-Renal Physiology. 313:F699-F705
The early events that signal renal dysfunction in presymptomatic heart failure are unclear. We tested the hypothesis that functional and mechanistic changes occur in the kidney that precede the development of symptomatic heart failure. We employed a
Autor:
Shenuarin Bhuiyan, Iñigo Valiente-Alandi, Jeffrey Robbins, Burns C. Blaxall, Jeffery D. Molkentin, James Gulick, Qinghang Meng, Bidur Bhandary, Hanna Osinska, Kritton Shay-Winkler, Jeanne James
Publikováno v:
Circulation research. 123(12)
Rationale: Hypertrophic cardiomyopathy occurs with a frequency of about 1 in 500 people. Approximately 30% of those affected carry mutations within the gene encoding cMyBP-C (cardiac myosin binding protein C). Cardiac stress, as well as cMyBP-C mutat