Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ben Goldacre"'
Autor:
Jack W. O’Sullivan, Sarah Stevens, Jason Oke, F. D. Richard Hobbs, Chris Salisbury, Paul Little, Ben Goldacre, Clare Bankhead, Jeffrey K. Aronson, Carl Heneghan, Rafael Perera
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Background The UK’s National Health Service (NHS) is currently subject to unprecedented financial strain. The identification of unnecessary healthcare resource use has been suggested to reduce spending. However, there is little very resear
Externí odkaz:
https://doaj.org/article/0637562a33144730a4c4853dfe769d61
Autor:
Edward P.K. Parker, Elsie M.F. Horne, William J. Hulme, John Tazare, Bang Zheng, Edward J. Carr, Fiona Loud, Susan Lyon, Viyaasan Mahalingasivam, Brian MacKenna, Amir Mehrkar, Miranda Scanlon, Shalini Santhakumaran, Retha Steenkamp, Ben Goldacre, Jonathan A.C. Sterne, Dorothea Nitsch, Laurie A. Tomlinson
Publikováno v:
The Lancet Regional Health - Europe. :100636
Autor:
Xiaomin Zhong, Alexander Pate, Ya-Ting Yang, Ali Fahmi, Darren M. Ashcroft, Ben Goldacre, Brian MacKenna, Amir Mehrkar, Sebastian CJ. Bacon, Jon Massey, Louis Fisher, Peter Inglesby, Kieran Hand, Tjeerd van Staa, Victoria Palin
Publikováno v:
The Lancet Regional Health - Europe. :100653
Autor:
Michael Moore, Jane Armitage, Ian Roberts, Andrew Thayne, Emily Herrett, Alexander Perkins, Haleema Shakur-Still, Elizabeth A. Williamson, Danielle Beaumont, Thomas M. MacDonald, Tjeerd van Staa, Danielle Prowse, Kieran Brack, Ben Goldacre, Zahra Jamal, Maurice Hoffman, Liam Smeeth
Publikováno v:
Health Technology Assessment, Vol 25, Iss 16 (2021)
Health Technol Assess
Health Technol Assess
Background Uncertainty persists about whether or not statins cause symptomatic muscle adverse effects (e.g. pain, stiffness and weakness) in the absence of severe myositis. Objectives To establish the effect of statins on all muscle symptoms, and the
Autor:
Anna Schultze, Emily Nightingale, David Evans, William Hulme, Alicia Rosello, Chris Bates, Jonathan Cockburn, Brian MacKenna, Helen J Curtis, Caroline E Morton, Richard Croker, Seb Bacon, Helen I McDonald, Christopher T Rentsch, Krishnan Bhaskaran, Rohini Mathur, Laurie A Tomlinson, Elizabeth J Williamson, Harriet Forbes, John Tazare, Daniel Grint, Alex J Walker, Peter Inglesby, Nicholas J DeVito, Amir Mehrkar, George Hickman, Simon Davy, Tom Ward, Louis Fisher, Amelia CA Green, Kevin Wing, Angel YS Wong, Robert McManus, John Parry, Frank Hester, Sam Harper, Stephen JW Evans, Ian J Douglas, Liam Smeeth, Rosalind M Eggo, Ben Goldacre, David A Leon
Publikováno v:
The Lancet Regional Health. Europe, Vol 14, Iss, Pp 100295-(2022)
Schultze, A, Nightingale, E, Evans, D, Hulme, W, Rosello, A, Bates, C, Cockburn, J, MacKenna, B, Curtis, H J, Morton, C E, Croker, R, Bacon, S, McDonald, H I, Rentsch, C T, Bhaskaran, K, Mathur, R, Tomlinson, L A, Williamson, E J, Forbes, H, Tazare, J, Grint, D, Walker, A J, Inglesby, P, DeVito, N J, Mehrkar, A, Hickman, G, Davy, S, Ward, T, Fisher, L, Green, A CA, Wing, K, Wong, A YS, McManus, R, Parry, J, Hester, F, Harper, S, Evans, S JW, Douglas, I J, Smeeth, L, Eggo, R M, Goldacre, B & Leon, D A 2022, ' Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic : an observational study of 4.3 million adults over the age of 65 ', The Lancet Regional Health-Europe, vol. 14, 100295 . https://doi.org/10.1016/j.lanepe.2021.100295
The Lancet Regional Health-Europe
Schultze, A, Nightingale, E, Evans, D, Hulme, W, Rosello, A, Bates, C, Cockburn, J, MacKenna, B, Curtis, H J, Morton, C E, Croker, R, Bacon, S, McDonald, H I, Rentsch, C T, Bhaskaran, K, Mathur, R, Tomlinson, L A, Williamson, E J, Forbes, H, Tazare, J, Grint, D, Walker, A J, Inglesby, P, DeVito, N J, Mehrkar, A, Hickman, G, Davy, S, Ward, T, Fisher, L, Green, A CA, Wing, K, Wong, A YS, McManus, R, Parry, J, Hester, F, Harper, S, Evans, S JW, Douglas, I J, Smeeth, L, Eggo, R M, Goldacre, B & Leon, D A 2022, ' Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic : an observational study of 4.3 million adults over the age of 65 ', The Lancet Regional Health-Europe, vol. 14, 100295 . https://doi.org/10.1016/j.lanepe.2021.100295
The Lancet Regional Health-Europe
Background Residents in care homes have been severely impacted by COVID-19. We describe trends in the mortality risk among residents of care homes compared to private homes. Methods On behalf of NHS England we used OpenSAFELY-TPP to calculate monthly
Autor:
Daniel Grint, Jonathan Cockburn, Rosalind M Eggo, Stephen J. W. Evans, Frank Hester, Ben Goldacre, Laurie A. Tomlinson, Brian MacKenna, Helen J Curtis, Christopher T Rentsch, Elizabeth A. Williamson, Alex J Walker, Peter Inglesby, Caroline E Morton, David Spiegelhalter, Krishnan Bhaskaran, Ian J. Douglas, Sebastian Bacon, Amir Mehrkar, Dave Evans, Chris Bates, Sam Harper, Anna Schultze, John Parry, Liam Smeeth, William J Hulme, Helen Mcdonald
Publikováno v:
The Lancet Regional Health. Europe
The Lancet Regional Health. Europe, Vol 6, Iss, Pp 100109-(2021)
The Lancet Regional Health. Europe, Vol 6, Iss, Pp 100109-(2021)
BackgroundMortality from COVID-19 shows a strong relationship with age and pre-existing medical conditions, as does mortality from other causes. However it is unclear how specific factors are differentially associated with COVID-19 mortality as compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79974c668cf2546225dc4d5249ec400b
https://doi.org/10.1101/2021.01.15.21249756
https://doi.org/10.1101/2021.01.15.21249756
Autor:
David G. Harrison, Richard Croker, Krishnan Bhaskaran, Laurie A. Tomlinson, John Parry, Ian J. Douglas, Liam Smeeth, Richard Grieve, Elizabeth A. Williamson, Sam Harper, Jonathan Cockburn, Harriet Forbes, Frank Hester, Helen J Curtis, Peter Inglesby, Chris Bates, Christopher T Rentsch, Alex J Walker, Helen Mcdonald, Caroline E Morton, Stephen J. W. Evans, Rafael Perera, Seb Bacon, Brian MacKenna, David M. Evans, Anna Schultze, Angel Y S Wong, Rohini Mathur, Ben Goldacre, Amir Mehrkar
Publikováno v:
Nature
Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide1. There is unprecedented urgency to understand who is most at risk of severe outcomes, and this requires new approaches for the timely analysis of large datasets. Working on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe21f1337c77f538b927de233e001e0
https://doi.org/10.1038/s41586-020-2521-4
https://doi.org/10.1038/s41586-020-2521-4
Publikováno v:
Healthcare, Vol 7, Iss 4, p 134 (2019)
Healthcare
Healthcare
In this paper we discuss the value of N-of-1 trials in personalising health care. We describe the challenges faced in implementing N-of-1 trials in the United Kingdom’s National Health Service and suggest how making greater use of these personalise
Autor:
Paul Little, Jeffrey K Aronson, FD Richard Hobbs, Carl Heneghan, Jason Oke, Jack W. O’Sullivan, Chris Salisbury, Sarah Stevens, Ben Goldacre, Clare Bankhead, Rafael Perera
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
BMC Medicine
O'Sullivan, J, Perera-Salazar, R, Heneghan, C, Salisbury, C, Goldacre, B, Little, P, Oke, J, Stevens, S, Hobbs, F D R, Bankhead, C & Aronson, J 2018, ' Practice variation in the use of tests in UK primary care : A retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16 ', BMC Medicine, vol. 16, 229 . https://doi.org/10.1186/s12916-018-1217-1
BMC Medicine
O'Sullivan, J, Perera-Salazar, R, Heneghan, C, Salisbury, C, Goldacre, B, Little, P, Oke, J, Stevens, S, Hobbs, F D R, Bankhead, C & Aronson, J 2018, ' Practice variation in the use of tests in UK primary care : A retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16 ', BMC Medicine, vol. 16, 229 . https://doi.org/10.1186/s12916-018-1217-1
Background The UK’s National Health Service (NHS) is currently subject to unprecedented financial strain. The identification of unnecessary healthcare resource use has been suggested to reduce spending. However, there is little very research quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c795be295130b84d131bf32b19b56e
https://doi.org/10.1186/s12916-018-1217-1
https://doi.org/10.1186/s12916-018-1217-1
In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) regulates medicines and medical devices, and monitors them to ensure they continue to meet quality and safety standards.1 However, recent controversies with both medicines2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59f034d84d03615b6708d169f87c89f
https://doi.org/10.1136/bmjebm-2018-111018
https://doi.org/10.1136/bmjebm-2018-111018