Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hsun–Ming Chang"'
Publikováno v:
The FASEB Journal. 34:16129-16143
Locally produced in human granulosa cells of the developing follicle, bone morphogenetic protein 2 (BMP2) plays a crucial role in the regulation of ovarian folliculogenesis and luteal formation. Brain-derived neurotrophic factor (BDNF) is an intraova
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-16 (2021)
Reproductive Biology and Endocrinology : RB&E
Reproductive Biology and Endocrinology : RB&E
Background Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8) and their functional receptors are expressed in human ovarian follicles, and these two intrafollicular factors play essential roles in regulating follicle developm
Autor:
Yingpu Sun, Avinash Thakur, Peter C.K. Leung, Yiran Li, Sijia Wang, Jung-Chien Cheng, Yuxi Li, Lanlan Fang, Hsun-Ming Chang, Yang Yan, Yuyin Yi
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 3, Pp 450-460 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Ovarian hyperstimulation syndrome (OHSS) is one of the most serious and iatrogenic complications that can occur during in vitro fertilization treatment. Although the pathogenesis of OHSS is not fully understood, vascular endothelial growth factor (VE
Autor:
Zheying Min, Yun Ren, Xiumei Zhen, Hongcui Zhao, Rong Li, Tianjie Li, Yang Yu, Yilei He, Kai-Lun Hu, Hsun-Ming Chang
Publikováno v:
Reproductive Sciences. 26:1429-1438
Kisspeptins are a family of neuropeptides that are essential for fertility. Recent experimental data suggest a putative role of kisspeptin signaling in the direct control of ovarian function. To explore the expression of KISS1 and KISS1 receptor (KIS
Publikováno v:
The FASEB Journal. 35
Serine protease inhibitor-E2 (SERPINE2) is highly expressed in the granulosa cells of growing follicles and the dynamic changes in SERPINE2 expression are correlated with follicular development and ovulation in several mammals, including mice, cattle
Publikováno v:
Molecular and cellular endocrinology. 536
Bone morphogenetic protein 6 (BMP6) and connective tissue growth factor (CTGF) are critical growth factors required for normal follicular development and luteal function. Cluster of Differentiation 68 (CD68) is an intraovarian marker of macrophages t
Publikováno v:
Endocrinology. 159:2926-2938
Bone morphogenetic protein (BMP) 6 is a critical regulator of follicular development that is expressed in mammalian oocytes and granulosa cells. Glial cell line‒derived neurotrophic factor (GDNF) is an intraovarian neurotrophic factor that plays an
Publikováno v:
Molecular and Cellular Endocrinology. 461:89-99
Lithium chloride (LiCl) is a widely-used medication to treat neurological disorders that has undesirable side effects on the female reproductive system. It has been show that LiCl can inhibit ovarian folliculogenesis, promote follicle atresia and sup
Publikováno v:
Molecular and Cellular Endocrinology. 434:186-198
Lysyl oxidase (LOX) is an essential enzyme for the stabilization of the extracellular matrix (ECM) and the subsequent follicle and oocyte maturation. Currently, there is limited information pertaining to the regulation of LOX activity in human ovaria
Publikováno v:
Cellular signalling. 63
Hyaluronan serves as a structural component of ovarian follicles, and hyaluronan-mediated signaling cascades lead to follicular development, oocyte maturation, and ovulation. Transforming growth factor-β (TGF-β1) is highly expressed in human oocyte