Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hsun–Ming Chang"'
Publikováno v:
The FASEB Journal. 34:16129-16143
Locally produced in human granulosa cells of the developing follicle, bone morphogenetic protein 2 (BMP2) plays a crucial role in the regulation of ovarian folliculogenesis and luteal formation. Brain-derived neurotrophic factor (BDNF) is an intraova
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-16 (2021)
Reproductive Biology and Endocrinology : RB&E
Reproductive Biology and Endocrinology : RB&E
Background Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8) and their functional receptors are expressed in human ovarian follicles, and these two intrafollicular factors play essential roles in regulating follicle developm
Publikováno v:
Molecular and cellular endocrinology. 535
Three major endothelial cell junctional adhesion molecules (VCAM1, ICAM1 and E-SELECTIN) play important roles in the process of angiogenesis, a progression of extensive physiological vascularization that occurs during the formation of the corpus lute
Publikováno v:
Endocrinology. 159:2926-2938
Bone morphogenetic protein (BMP) 6 is a critical regulator of follicular development that is expressed in mammalian oocytes and granulosa cells. Glial cell line‒derived neurotrophic factor (GDNF) is an intraovarian neurotrophic factor that plays an
Publikováno v:
Molecular and Cellular Endocrinology. 434:186-198
Lysyl oxidase (LOX) is an essential enzyme for the stabilization of the extracellular matrix (ECM) and the subsequent follicle and oocyte maturation. Currently, there is limited information pertaining to the regulation of LOX activity in human ovaria
Publikováno v:
Endocrinology. 159(4)
Transforming growth factor-β (TGF-β) 1 plays a critical role in regulating follicular development, and its dysregulation has been shown to be involved in the pathogenesis of ovulation dysfunction. SNAIL is a well-known transcriptional repressor tha
Autor:
Jung-Chien Cheng, Horng-Der Tsai, Hsun-Ming Chang, Peter C.K. Leung, Cheng-Hsuan Wu, Yu-Ching Chen
Publikováno v:
Human Reproduction. 30:2190-2201
STUDY QUESTION Does transforming growth factor-β1 (TGF-β1) up-regulate connexin43 (Cx43) to promote cell-cell communication in human granulosa cells? SUMMARY ANSWER TGF-β1 up-regulates Cx43 and increases gap junction intercellular communication ac
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E375-E386
Granulosa cell-derived activins play important roles in the regulation of ovarian functions. To date, there is limited information pertaining to the intracellular regulation, assembly, and secretion of endogenous activin A in human granulosa cells.Th
Autor:
Lanlan Fang, Elizabeth L. Taylor, Peter C.K. Leung, Xin Qiu, Christian Klausen, Hsun-Ming Chang, Jung-Chien Cheng
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E365-E374
Theca cell-derived bone morphogenetic protein 4 (BMP4) and BMP7 are important regulators of folliculogenesis and have been shown to inhibit luteinization. Pentraxin 3 (PTX3) plays a critical role in the assembly of the cumulus oophorus extracellular
Autor:
Jung-Chien Cheng, Ying-Pu Sun, Hsun-Ming Chang, Peter C.K. Leung, Christian Klausen, Lanlan Fang
Publikováno v:
Molecular and Cellular Endocrinology. 404:82-90
Growth differentiation factor 8 (GDF8), also known as myostatin, is highly expressed in the mammalian musculoskeletal system and plays critical roles in the regulation of skeletal muscle growth. Though not exclusively expressed in the musculoskeletal