Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wengang Chai"'
Autor:
Zhimou Guo, Angelina S. Palma, Xinmiao Liang, Hongzhi Cao, Jingyu Yan, Tian Gao, Chang Cheng Liu, Min Xiao, Xi Chen, Wengang Chai
Publikováno v:
Journal of the American Chemical Society. 141:19351-19359
The human natural killer-1 (HNK-1) epitope is a unique sulfated trisaccharide sequence presented on O- and N-glycans of various glycoproteins and on glycolipids. It is overexpressed in the nervous system and plays crucial roles in nerve regeneration,
Autor:
Ten Feizi, Barbara Mulloy, Wengang Chai, Yibing Zhang, Sandro Sonnino, Maria Grazia Ciampa, Laura Mauri
Publikováno v:
Journal of the American Society for Mass Spectrometry
Gangliosides, as plasma membrane-associated sialylated glycolipids, are antigenic structures and they serve as ligands for adhesion proteins of pathogens, for toxins of bacteria, and for endogenous proteins of the host. The detectability by carbohydr
Autor:
Yan Li, Chuncui Huang, Wengang Chai, Wenchun Xie, Jinyu Zhou, Shiwei Sun, Hui Wang, Jingyu Yan, Huanyu Gao
Publikováno v:
Carbohydrate Polymers. 229:115528
Carbohydrate sequences are important for various biological processes. It has recently been estimated to have 100,000–500,000 carbohydrate structures in mammalian glycome. However, the peripheral carbohydrate determinants on N- and O-glycoproteins,
Autor:
Ten Feizi, Yan Liu, Angelina S. Palma, Colin G. Herbert, Wengang Chai, Denong Wang, Robert A. Childs
Publikováno v:
Biochemical and Biophysical Research Communications. 408:548-552
The term human epithelial carcinoma antigen (HCA) has been applied collectively to mucin-type high molecular weight (>1000 kDa) glycoproteins that are over-expressed in epithelial cancers. Since the 1990s, over 40 monoclonal antibodies have been rais
Publikováno v:
Nature Biotechnology. 20:1011-1017
We describe microarrays of oligosaccharides as neoglycolipids and their robust display on nitrocellulose. The arrays are obtained from glycoproteins, glycolipids, proteoglycans, polysaccharides, whole organs, or from chemically synthesized oligosacch
Autor:
Chao, Gao, Yan, Liu, Hongtao, Zhang, Yibing, Zhang, Michiko N, Fukuda, Angelina S, Palma, Radoslaw P, Kozak, Robert A, Childs, Motohiro, Nonaka, Zhen, Li, Don L, Siegel, Peter, Hanfland, Donna M, Peehl, Wengang, Chai, Mark I, Greene, Ten, Feizi
Publikováno v:
The Journal of Biological Chemistry
Background: F77 is a previously uncharacterized prostate cancer-associated antigen. Results: Using a microarray of sequence-defined glycolipids and neoglycolipids, mucin-O-glycan designer arrays, and mass spectrometry, we demonstrate that F77 antibod
Autor:
Wengang Chai, Chun-Ting Yuen, Ten Feizi, R. Wendy Loveless, Richard U. Margolis, Alexander M. Lawson
Publikováno v:
Journal of Biological Chemistry. 272:8924-8931
The monoclonal antibody HNK-1 originally raised to an antigenic marker of natural killer cells also binds to selected regions in nervous tissue. The antigen is a carbohydrate that has attracted much interest as its expression is developmentally regul
Autor:
Xiaobei Zhan, Hongtao Zhang, Shuang Zhang, Yibing Zhang, Guanjun Tao, Barbara Mulloy, Wengang Chai
Publikováno v:
Analytical chemistry. 85(12)
Blood-group antigens, such as those containing fucose and bearing the ABO(H)- and Lewis-type determinants expressed on the carbohydrate chains of glycoproteins and glycolipids, and also on unconjugated free oligosaccharides in human milk and other se
Autor:
Chun-Ting Yuen, Ten Feizi, Katsuko Sudo, Mikael L. Gustavsson, Masatake Araki, Alexander M. Lawson, Taka Osanai, Kimi Araki, Wengang Chai
Publikováno v:
Biochemical and Biophysical Research Communications. 218:610-615
In search of endogenous oligosaccharide ligands for the endothelial adhesion molecule E-selectin in mouse, glycolipids from tissues and the neutrophilic cell line 32D c13 were tested for E-selectin binding. Kidneys of BALB/c and NMRI mice (but not CB
Autor:
Mark S. Stoll, Ten Feizi, Alexander M. Lawson, Franz-Georg Hanisch, Wengang Chai, Jerzy R. Rosankiewicz
Publikováno v:
European Journal of Biochemistry. 217:645-655
Mucins from the pooled gastric juice of Lewis-positive secretors were investigated to establish their glycosylation patterns with particular reference to the type and abundance of the glycan-core structures. Following reductive beta-elimination, the