Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Caixia Yin"'
Publikováno v:
Chemical Communications. 58:4881-4884
A mitochondrial targeted NIR fluorescent probe NIR-NBD was designed and developed for the detection of biothiols and viscosity. Furthermore, a positive correlation between the biothiol level and viscosity under cellular stress change was found for th
Publikováno v:
Chinese Chemical Letters. 32:3870-3875
Mitochondria is the main organelle for the production of reactive sulfur species (RSS), such as homocysteine (Hcy), cysteine (Cys), glutathione (GSH) and sulfur dioxide (SO2), etc. These compounds participate in a large number of physiological proces
Publikováno v:
Chinese Chemical Letters. 32:2873-2876
The development of fluorescent probes enabling to distinguish Cys, Hcy and GSH has always been a considerable challenge, in particular the distinction of Hcy and other two biothiols, because Hcy has a very similar structure with Cys and a relatively
Publikováno v:
New Journal of Chemistry. 45:9096-9101
An abnormal concentration of glutathione (GSH) is a health-associated risk factor and it is an important signal for diseases such as Parkinson's disease, liver injury and cancer. Therefore, understanding the real-time level of GSH is essential for th
Publikováno v:
The Analyst. 146:4666-4673
Biological thiols (Cys, Hcy and GSH) are crucial biomolecules in living cells and play indispensable roles in maintaining the redox homeostasis of organisms. But due to their similar molecular structure, the development of effective tools for disting
Publikováno v:
Chemical Science
Abnormal concentrations of biothiols such as cysteine, homocysteine and glutathione are associated with various major diseases. In biological systems, the structural similarity and functional distinction of these three small molecular thiols has not
Publikováno v:
Journal of the American Chemical Society. 143:318-325
Biosynthesis is a necessary process to maintain life. In recent years, research has fully shown that three kinds of biothiols (Cys, Hcy, GSH) mainly play the role in oxidative stress and maintaining cell homeostasis in cells, and that abnormal concen
Publikováno v:
Chinese Chemical Letters. 31:2970-2974
Cysteine (Cys) plays an important role in regulating cellular redox balance. But due to the constant changes in the concentration of Cys in organisms, fast response sensors are urgent required for practical application. In this work, a fluorescent pr
Autor:
yunze zhai, Dongdong Chen, Yongkang Yue, wenjing zhao, Caixia Yin, Tao Liu, xufeng yang, zilong guo
Publikováno v:
Chemical communications (Cambridge, England). 57(100)
The host–guest type molecular size matching strategy, which embodied intramolecular hydrogen bond, aromatic nucleophilic substitution and nucleophilic addition, was utilized to develop a fluorescent probe for GSH specific detection and in situ imag
Publikováno v:
Journal of the American Chemical Society. 142:6324-6331
Glutathione (GSH) mediates a wide variety of biological events and human diseases. Although it has been the subject of intense study in recent years, a further understanding of its molecular mechanisms and metabolism routes in living cells has remain