Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fei Yin"'
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 46(14)
Type 2 diabetes mellitus( T2 DM) is a common chronic metabolic disease characterized by persistent hyperglycemia and insulin resistance. In pancreatic β-cells,glucose-stimulated insulin secretion( GSIS) plays a pivotal role in maintaining the balanc
Publikováno v:
Cell Biochemistry and Function. 37:368-376
The growing evidence shows that in the early stage of type 2 diabetes mellitus (T2DM) development, when challenged by hyperglycemia and/or insulin resistance, pancreatic islets would produce more insulin to maintain the balance of blood sugar, but at
Publikováno v:
Cell biology internationalReferences. 44(7)
Thioredoxin-interacting protein (Txnip), a negative regulator of thioredoxin, has become an attractive therapeutic target to alleviate metabolic diseases. Our previous data demonstrated that geniposide improved glucose-stimulated insulin secretion by
Publikováno v:
Cell biology international. 41(5)
Our previous works indicated that geniposide could regulate glucose-stimulated insulin secretion (GSIS), and improved chronic high glucose-induced dysfunctions in pancreatic β cells, but the molecular mechanisms remain largely unknown. In the presen
Publikováno v:
Journal of endocrinological investigation. 40(5)
To analyze the role of geniposide in the protein degradation of Txnip and to determine the impact of Txnip on geniposide-regulated GSIS in pancreatic INS-1 cells. The content of Txnip protein was measured by western blot; insulin content and glucose
Autor:
Fei Yin, Jing Peng, Xiaolu Deng, Muhammad Usman Ashhab, Na Gan, Ahmed Omran, Fang He, Liwen Wu, Huimin Kong
Publikováno v:
Neurochemical Research. 39:233-243
Microglia plays important role in central nervous system immune surveillance and has emerged as an essential cellular component for understanding brain diseases. MicroRNAs (miRs) are small, noncoding RNAs that regulate the post-transcriptional expres
Publikováno v:
Journal of natural medicines. 71(1)
Our previous work showed that geniposide affected glucose-stimulated insulin secretion (GSIS) via regulating glucose uptake and metabolism in pancreatic β cells; however, the molecular mechanisms remain largely unknown. Substantial evidence suggests
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 305(10)
Acrolein, an α,β unsaturated electrophile, is an environmental pollutant released in ambient air from diesel exhausts and cooking oils. This study examines the role of acrolein in altering mitochondrial function and metabolism in lung-specific cell
This study examines the progress of a hypometabolic state inherent in brain aging with an animal model consisting of Fischer 344 rats of young, middle, and old ages. Dynamic microPET scanning demonstrated a significant decline in brain glucose uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07553ab3f7bc7d765472208ac46a2512
https://europepmc.org/articles/PMC3819405/
https://europepmc.org/articles/PMC3819405/
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78315 (2013)
PLoS ONE
PLoS ONE
Glucose-stimulated insulin secretion (GSIS) is essential to the control of metabolic fuel homeostasis. The impairment of GSIS is a key element of β-cell failure and one of causes of type 2 diabetes mellitus (T2DM). Although the KATP channel-dependen