Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pankaj Vats"'
Autor:
Kathryn McFadden, Arul M. Chinnaiyan, Andrew H. Zureick, Bailey Anderson, Sriram Venneti, Lili Zhao, Robert J. Lonigro, Karin M. Muraszko, Bernard L. Marini, Brendan Mullan, Patricia L. Robertson, Xuhong Cao, Pankaj Vats, Marcin Cieslik, Rajen Mody, Carl Koschmann, Jessica Everett, Paul E. McKeever, Sandra Camelo-Piragua, Yi-Mi Wu, Marcia Leonard, Hugh J. L. Garton, Cormac O. Maher, Andrew P. Lieberman, Katayoon Kasaian, Kevin Frank, John R. Prensner, Dan R. Robinson, Chandan Kumar-Sinha
Publikováno v:
JCO Precis Oncol
Purpose Brain tumors have become the leading cause of cancer-related mortality in young patients. Novel effective therapies on the basis of the unique biology of each tumor are urgently needed. The goal of this study was to evaluate the feasibility,
Autor:
Nicole D. Lee, Pankaj Vats, Saravana M. Dhanasekaran, Fengyun Su, Rohit Mehra, Arul M. Chinnaiyan, Robert J. Lonigro, Kumpati Premkumar, Jesse K. McKenney, Kiril Trpkov, Xuhong Cao
Publikováno v:
European Urology. 74:483-486
Renal cell carcinomas (RCC) with overlapping histomorphologic features poses diagnostic challenges. This is exemplified in RCCs with eosinophilic cytoplasm that include eosinophilic solid and cystic RCC (ESC RCC), RCCs in germline aberrations of tube
Autor:
David Smith, Moshe Talpaz, Megan E.V. Caram, Scott M. Schuetze, Mark M. Zalupski, Daniel F. Hayes, Erin F. Cobain, Chandan Kumar-Sinha, Robert J. Lonigro, Arul M. Chinnaiyan, Anne F. Schott, Erica Rabban, Elena M. Stoffel, Rashmi Chugh, Yi-Mi Wu, Vaibhav Sahai, Dan R. Robinson, Yu Ning, Michelle F. Jacobs, Ajjai Alva, Aaron M. Udager, Sandra Camelo-Piragua, Xuhong Cao, Pankaj Vats, Lakshmi P. Kunju, Francis P. Worden, Rui Wang, Marcin Cieslik, David R. Lucas, Janice Bell
Publikováno v:
JAMA Oncology
Key Points Question What is the clinical utility of genomic profiling for patients with advanced solid tumors? Findings In this cohort study of 1015 patients who underwent integrative genomic profiling, a high rate of pathogenic germline variants and
Autor:
Pankaj Vats, Tobias Else, Kazutaka Nanba, Amy R Blinder, Samuel W. Plaska, Thomas J. Giordano, Aaron M. Udager, Chandan Kumar-Sinha, Juilee Rege, William E. Rainey
Publikováno v:
Journal of the Endocrine Society
Somatic mutations driving aldosterone production have been identified in approximately 90% of aldosterone-producing adenomas (APAs) using an aldosterone synthase (CYP11B2) immunohistochemistry (IHC)-guided DNA sequencing approach. In the present stud
Autor:
Daniel L. Hertz, Erika Mora, Pankaj Vats, Bailey Anderson, Yi-Mi Wu, Rajen Mody, Kevin Frank, Andrew Glatz, Amy L. Pasternak, Dan R. Robinson, Robert J. Lonigro, Arul M. Chinnaiyan, Erica Rabban
Publikováno v:
JCO Precis Oncol
Purpose Evidence-based guidelines inform treatment decisions for patients for whom germline genetic information is available. Our real-time tumor sequencing program, which makes precision treatment decisions for patients with cancer, produces matched
Autor:
Yi-Mi Wu, Dan R. Robinson, Michelle F. Jacobs, Moshe Talpaz, Erin F. Cobain, Pankaj Vats, Rashmi Chugh, Elena M. Stoffel, Arul M. Chinnaiyan
Publikováno v:
Journal of Clinical Oncology. 38:1501-1501
1501 Background: Tumor molecular profiling via next-generation sequencing (NGS) is routinely utilized to direct patients toward clinical trials of targeted therapeutics. NGS testing of paired tumor/normal samples identifies incidental pathogenic germ
Autor:
Pankaj Vats, Sarvana Mohan Dhanashekaran, Sudhanshu Shukla, Jincheng Pan, Marston Linehan, Yuping Zhang, Christopher J. Ricketts, Rui Wang, Arul M. Chinnaiyan, Xuhong Cao, Fengyun Su, Marcin Cieslik, Prem Kumar Kumpati, Ajjai Alva, Narayanan Sathiya Pandi, Rohit Mehra
Publikováno v:
Cancer Research. 79:730-730
Background Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) is a rare autosomal-dominant syndromic disorder associated with germline FH mutations. Affected individuals have a predisposition to cutaneous and uterine leiomyoma’s, and are at
Autor:
Arul M. Chinnaiyan, Pankaj Vats, Saravana M. Dhanasekaran, Jesse K. McKenney, Kiril Trpkov, Xuhong Cao, Nicole D. Lee, Kumpati Premkumar, Robert J. Lonigro, Rohit Mehra, Fengyun Su
Publikováno v:
Cancer Research. 78:5342-5342
Renal cell carcinoma (RCC) subtypes with overlapping histomorphologic features pose diagnostic challenges. For instance, a unique category of sporadic renal tumors with eosinophilic cytoplasm and solid and cystic growth pattern (ESC RCC) may mimic a
Autor:
Pankaj Vats, Dan R. Robinson, Erika Mora, Arul M. Chinnaiyan, Xuhong Cao, Robert J. Lonigro, Daniel L. Hertz, Andrew Nobani, Yi-Mi Wu, Rajen Mody
Publikováno v:
Journal of Clinical Oncology. 34:1583-1583
1583Background: Tumor genetic profiling to identify oncogenic drivers and select targeted agents is rapidly proliferating. Patient (germline) genetic information produced concurrent with tumor prof...
Autor:
Irfan A. Asangani, Raja Rabah, Elena M. Stoffel, Robert J. Lonigro, Jeffrey W. Innis, Arul M. Chinnaiyan, L.P. Kunju, John R. Prensner, Xuhong Cao, Nallasivam Palanisamy, Kevin Frank, Yi-Mi Wu, Jessica Everett, Rajen Mody, Pankaj Vats, Sameek Roychowdhury, Dan R. Robinson
Publikováno v:
Cancer Research. 76:PR07-PR07
Introduction: Integrated clinical sequencing (RNA and whole-exome) has been used to assist in clinical decision making for pediatric and young adult cancer patients in the Peds-MiOncoSeq study. Here we present novel biological findings from this stud