Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pratik Choudhary"'
Autor:
Anneliese Flatt, Claire Counter, Martin K. Rutter, Andrew J. Sutherland, Shareen Forbes, Miranda Rosenthal, Mirka Pimkova, Keith Burling, A Pernet, Peter Barker, Paul Johnson, Ruth Wood, Denise Bennett, Robert Crookston, James Shaw, Alistair Lumb, Linda Birtles, Pratik Choudhary, John Casey
Publikováno v:
Forbes, S, Flatt, A J, Bennett, D, Crookston, R, Pimkova, M, Birtles, L, Pernet, A, Wood, R C, Burling, K, Barker, P, Counter, C, Lumb, A, Choudhary, P, Rutter, M K, Rosenthal, M, Sutherland, A, Casey, J, Johnson, P & Shaw, J A M 2021, ' The impact of islet mass, number of transplants, and time between transplants on graft function in a national islet transplant program ', American Journal of Transplantation . https://doi.org/10.1111/ajt.16785
The UK islet allotransplant program is nationally funded to deliver one or two transplants over 12 months to individuals with type 1 diabetes and recurrent severe hypoglycemia. Analyses were undertaken 10 years after program inception to evaluate ass
Autor:
Inmaculada Ruz-Maldonado, Bo Liu, Guo Cai Huang, Patricio Atanes, Shanta J. Persaud, Pratik Choudhary, Attilio Pingitore
Publikováno v:
Cellular and Molecular Life Sciences
Aims Endocannabinoids are lipid mediators involved in the regulation of glucose homeostasis. They interact with the canonical cannabinoid receptors CB1 and CB2, and it is now apparent that some cannabinoid receptor ligands are also agonists at GPR55.
Autor:
Aaron Liew, Martin K. Rutter, Jane Speight, Denise Bennett, John Casey, Paul Johnson, James Shaw, Miranda Rosenthal, Ruth Wood, Linda Birtles, Shareen Forbes, Robert Crookston, Pratik Choudhary, Elizabeth Holmes-Truscott, A Pernet, Mirka Pimkova, Anneliese Flatt
Publikováno v:
Islets
article-version (VoR) Version of Record
Liew, A, Holmes-Truscott, E, Flatt, A JS, Bennett, D, Crookston, R, Pimkova, M, Birtles, L, Caey, J, Pernet, A, Wood, R C, Choudhary, P, Forbes, S, Rutter, M K, Rosenthal, M J, Johnson, P J, Shaw, J & speight, J 2020, ' Characterization of pre-transplant psychosocial burden in an integrated national islet transplant programme ', Islets . https://doi.org/10.1080/19382014.2020.1736740
article-version (VoR) Version of Record
Liew, A, Holmes-Truscott, E, Flatt, A JS, Bennett, D, Crookston, R, Pimkova, M, Birtles, L, Caey, J, Pernet, A, Wood, R C, Choudhary, P, Forbes, S, Rutter, M K, Rosenthal, M J, Johnson, P J, Shaw, J & speight, J 2020, ' Characterization of pre-transplant psychosocial burden in an integrated national islet transplant programme ', Islets . https://doi.org/10.1080/19382014.2020.1736740
The psychological burden experienced by people with diabetes prior to islet transplantation is recognized but has not been studied comprehensively, especially in relation to glycemia. Therefore, we conducted a rigorous pre-operative psychosocial prof
Autor:
Prv Johnson, James Bushnell, D van Dellen, John Casey, Shareen Forbes, James Shaw, Angela Summers, Iestyn M. Shapey, Pratik Choudhary, Martin K. Rutter, Petros Yiannoullou, Neil A. Hanley, Miranda Rosenthal, Titus Augustine, Hussein Khambalia, Catherine Fullwood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e76a668f0896868fa454885f995bc7
https://doi.org/10.1111/dom.14088/v2/response1
https://doi.org/10.1111/dom.14088/v2/response1
Autor:
Peter A. Senior, Marie-Christine Vantyghem, Lorenzo Piemonti, James Shaw, Esther Latres, Johann Pratschke, François Pattou, Eelco J.P. de Koning, Barbara Ludwig, Paul Johnson, Thierry Berney, Raja Kandaswamy, Rodolfo Alejandro, Roger Lehmann, James F. Markmann, Steven A. White, Thomas W.H. Kay, Robert M. Langer, Jon S. Odorico, Marjana Marinac, Michael R. Rickels, Bart Keymeulen, Peter G. Stock, Pratik Choudhary, Melena D. Bellin, Yogish C. Kudva
Publikováno v:
Transplant International, 31(4), 343-352
Transplantation, 102(9), 1479-1486
Transplantation, 102(9), 1479-1486. Lippincott Williams & Wilkins
Transplantation, Vol. 102, No 9 (2018) pp. 1479-1486
Transplant International, Vol. 31 (2018) pp. 343-352
Transplant International
Transplant international : official journal of the European Society for Organ Transplantation, 31(4), 343-352. Wiley-Blackwell
Transplantation, 102(9), 1479-1486
Transplantation, 102(9), 1479-1486. Lippincott Williams & Wilkins
Transplantation, Vol. 102, No 9 (2018) pp. 1479-1486
Transplant International, Vol. 31 (2018) pp. 343-352
Transplant International
Transplant international : official journal of the European Society for Organ Transplantation, 31(4), 343-352. Wiley-Blackwell
β-cell replacement therapy, available currently as pancreas or islet transplantation, has developed without a clear definition of graft functional and clinical outcomes. The International Pancreas and Islet Transplant Association and European Pancre
Autor:
Paramjeet Dhadda, Ahmed A. Arzouni, Chloe L. Rackham, Guo Cai Huang, Peter M. Jones, Aileen King, Pratik Choudhary, Andreia Vargas-Seymour, Nance Beyer Nardi
Publikováno v:
Arzouni, A A, Vargas-Seymour, A, Rackham, C L, Dhadda, P, Huang, G C, Choudhary, P, Nardi, N, King, A J F & Jones, P M 2017, ' Mesenchymal stromal cells improve human islet function through released products and extracellular matrix ', Clinical Science, vol. 131, no. 23, pp. 2835-2845 . https://doi.org/10.1042/CS20171251
Aims: The aims of the present study were (i) to determine whether the reported beneficial effects of mesenchymal stromal cells (MSCs) on mouse islet function extend to clinically relevant human tissues (islets and MSCs), enabling translation into imp
Autor:
Inmaculada Ruz-Maldonado, Attilio Pingitore, Bo Liu, Guo Cai Huang, Shanta J. Persaud, Pratik Choudhary
Publikováno v:
Pingitore, A, Ruz-Maldonado, I, Liu, B, Huang, G C, Choudhary, P & Persaud, S J 2017, ' Dynamic Profiling of Insulin Secretion and ATP Generation in Isolated Human and Mouse Islets Reveals Differential Glucose Sensitivity ', Cellular Physiology and Biochemistry, vol. 44, no. 4, pp. 1352-1359 . https://doi.org/10.1159/000485532
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1352-1359 (2017)
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1352-1359 (2017)
Background/Aims: Rodent islets are often used for basic science research but they do not always recapitulate signalling events in human islets. This study evaluated the glucose-dependent responses of human and mouse islets in terms of dynamic insulin
Autor:
Pratik Choudhary, Astrid C Hauge-Evans, Guo Cai Huang, Bo Liu, Peter M. Jones, Zara J. Franklin, Shanta J. Persaud, Alonso Vilches-Flores
Publikováno v:
BBA Clinical
Vilches-Flores, A, Franklin, Z, Hauge-Evans, A C, Liu, B, Huang, G C, Choudhary, P, Jones, P M & Persaud, S J 2016, ' Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction ', BBA Clinical . https://doi.org/10.1016/j.bbacli.2016.03.009
Vilches-Flores, A, Franklin, Z, Hauge-Evans, A C, Liu, B, Huang, G C, Choudhary, P, Jones, P M & Persaud, S J 2016, ' Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction ', BBA Clinical . https://doi.org/10.1016/j.bbacli.2016.03.009
Background Although in vivo studies have implicated endocannabinoids in metabolic dysfunction, little is known about direct, chronic activation of the endocannabinoid system (ECS) in human islets. Therefore, this study investigated the effects of pro
Autor:
Andreas Barthel, Stefan R. Bornstein, Stephanie A. Amiel, Min Zhao, Mei Mei Fung, Guo Huang, Pratik Choudhary, Parthi Srinivasan, Helen Tang, Nigel Heaton
Publikováno v:
Hormone and Metabolic Research. 47:72-77
Revascularisation of transplanted islets is an essential prerequisite for graft survival and function. However, current islet isolation procedures deprive the islets of endothelial tubulets. This may have a detrimental effect on the revascularisation
Autor:
Nantia Othonos, Pratik Choudhary
Publikováno v:
Current Diabetes Reports
Purpose of Review Episodic hypoglycemia is an almost inevitable consequence of exogenous insulin treatment of type 1 diabetes, and in up to 30% of patients, this can lead to impaired awareness of hypoglycemia. This predisposes to recurrent severe hyp