Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Thirumalaisamy P. Velavan"'
Autor:
Eduardo Delabio, Auer, Hoang Van, Tong, Leonardo Maldaner, Amorim, Danielle, Malheiros, Nghiem Xuan, Hoan, Hellen Caroline, Issler, Maria Luiza, Petzl-Erler, Márcia Holsbach, Beltrame, Angelica Beate Winter, Boldt, Nguyen Linh, Toan, Le Huu, Song, Thirumalaisamy P, Velavan, Danillo G, Augusto
Publikováno v:
International Journal of Infectious Diseases, Vol 96, Iss, Pp 541-547 (2020)
Objectives: Genes of host immunity play an important role in disease pathogenesis and are determinants of clinical courses of infections, including hepatitis B virus (HBV). Killer-cell immunoglobulin-like receptor (KIR), expressed on the surface of n
Autor:
Can Van Mao, Le Van Nam, Nguyen Truong Giang, Quyet Do, Nguyen Linh Toan, Trinh Huu Nghia, Hoang Van Tong, Ho Anh Son, Ngo Truong Giang, Hoang Vu Hung, Le Dinh Thanh, Do Tuan Anh, Thirumalaisamy P. Velavan
Publikováno v:
International Journal of Infectious Diseases, Vol 95, Iss, Pp 253-261 (2020)
Background and objective: The human ficolin-2, encoded by FCN2, recognizes pathogen-associated acetylated residues on their cell surfaces and activates the lectin complement cascade. This study aimed to investigate the contribution of human ficolin-2
Autor:
Pham Xuan Huy, Peter G. Kremsner, Can Van Mao, Dang Thuy Linh, Sivaramakrishna Rachakonda, Thirumalaisamy P. Velavan, Ngo Thu Hang, Dang Thanh Chung, Le Huu Song, Srinivas Reddy Pallerla, C-Thomas Bock, Heiner Wedemeyer, Le Minh Dung, Le Thi Kieu Linh, Hoang Van Tong, Bui Tien Sy, Nguyen Linh Toan
Publikováno v:
Pathogens
Volume 10
Issue 10
Pathogens, Vol 10, Iss 1340, p 1340 (2021)
Volume 10
Issue 10
Pathogens, Vol 10, Iss 1340, p 1340 (2021)
Infections with HEV in low- and middle-income countries (LMICs) are associated with increased rates of preterm birth, miscarriage, and stillbirth. The aim of the present study was to investigate HEV infections in pregnant women and the possibility of
Autor:
Nghiem Xuan Hoan, Pham Thi Minh Huyen, Mai Thanh Binh, Ngo Tat Trung, Dao Phuong Giang, Bui Thuy Linh, Dang Thi Ngoc Dung, Srinivas Reddy Pallerla, Peter G. Kremsner, Thirumalaisamy P. Velavan, Mai Hong Bang, Le Huu Song
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The inhibitory effects of programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) modulates T-cell depletion. T-cell depletion is one of the key mechanisms of hepatitis B virus (HBV) persistence, in particular liver disease progression an
Autor:
Francine Ntoumi, Christevy Vouvoungui, David Nderu, Felix Koukouikila-Koussounda, Simon Marie Peko, Simon Charles Kobawila, Thirumalaisamy P. Velavan
Publikováno v:
International Journal of Infectious Diseases, Vol 85, Iss, Pp 49-53 (2019)
Background: Cytochrome P450 (CYP) enzymes are essential in the metabolism of most drugs used today. Single nucleotide polymorphism(s) occurring in CYP genes can adversely affect drug pharmacokinetics, efficacy, and safety. Individuals carrying the CY
Autor:
Simon Charles Kobawila, Francine Ntoumi, Felix Koukouikila-Koussounda, Christevy Vouvoungui, Simon Marie Peko, David Nderu, Thirumalaisamy P. Velavan, Nerly Shirère Gampio Gueye
Publikováno v:
International Journal of Infectious Diseases, Vol 82, Iss, Pp 111-116 (2019)
Background: The cytochrome P450 CYP2B6*6 (CYP2B6 c.516G>T; rs3745274) is one of the genetic factors that alters the drug metabolism in antimalarial, antiretroviral and TB first-line drugs. In Central African populations, the distribution of the CYP2B
Autor:
Angelica Beate Winter Boldt, Camila de Freitas Oliveira-Toré, Gabriela Canalli Kretzschmar, Hellen Weinschutz Mendes, Sérvio Túlio Stinghen, Fabiana Antunes Andrade, Valéria Bumiller-Bini, Letícia Boslooper Gonçalves, Anna Carolina de Moraes Braga, Ewalda von Rosen Seeling Stahlke, Thirumalaisamy P. Velavan, Steffen Thiel, Iara José Taborda de Messias-Reason
Publikováno v:
Boldt, A B W, Oliveira-Toré, C D F, Kretzschmar, G C, Weinschutz Mendes, H, Stinghen, S T, Andrade, F A, Bumiller-Bini, V, Gonçalves, L B, Braga, A C D M, Stahlke, E V R S, Velavan, T P, Thiel, S & de Messias-Reason, I J T 2021, ' Hepatitis B Virus Infection Among Leprosy Patients : A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors ', Frontiers in Immunology, vol. 11, 574457 . https://doi.org/10.3389/fimmu.2020.574457
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Thousands of leprosy patients not only suffer from physical deformities, but also either have or have had hepatitis B virus (HBV) coinfection. Polymorphisms of the complement system modulate susceptibility to leprosy, but genetic susceptibility to pa
Autor:
Paul Alvyn Nguema Moure, Gedeon Bingoulou Matsougou, Alexandru Tomazatos, Thirumalaisamy P. Velavan, Benjamin Mordmüller, Simon Ategbo, Ayola A. Adegnika, Mirabeau Mbong Ngwese, Peter G. Kremsner, Moustapha Nzamba Maloum, Steffen Borrmann, Daniel Eibach, Sandra Niendorf, Gédéon Prince Manouana, Elie G. Rossatanga, C.-Thomas Bock
Publikováno v:
Ebiomedicine, 73
EBioMedicine
EBioMedicine, Vol 73, Iss, Pp 103648-(2021)
EBioMedicine
EBioMedicine, Vol 73, Iss, Pp 103648-(2021)
Background: Rotavirus A (RVA) causes acute gastroenteritis in children
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139446dd9c79640540be1f384320a8ca
http://hdl.handle.net/2066/241440
http://hdl.handle.net/2066/241440
Autor:
C-Thomas Bock, Benjamin Mordmüller, Sandra Niendorf, Paul Alvyn Nguema-Moure, Steffen Borrmann, Thirumalaisamy P. Velavan, Mirabeau Mbong Ngwese, Gédéon Prince Manouana, Daniel Eibach, Peter G. Kremsner, Ayola A. Adegnika
Publikováno v:
Viruses, 13
Viruses
Viruses, 13, 4
Viruses, Vol 13, Iss 545, p 545 (2021)
Volume 13
Issue 4
Viruses
Viruses, 13, 4
Viruses, Vol 13, Iss 545, p 545 (2021)
Volume 13
Issue 4
Enteric viruses are the leading cause of diarrhea in children globally. Identifying viral agents and understanding their genetic diversity could help to develop effective preventive measures. This study aimed to determine the detection rate and genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d43ac04b2245121dfa08d85e53bff79
http://hdl.handle.net/2066/238419
http://hdl.handle.net/2066/238419
Autor:
Hoang Vu Hung, Do Quyet, Ho Anh Son, Thirumalaisamy P. Velavan, Do Tuan Anh, Can Van Mao, Nguyen Linh Toan, Nguyen Minh Nam, Trinh Huu Nghia, Hoang Van Tong, Nghiem Xuan Hoan, Ngo Truong Giang, Christian Meyer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
The complement system may be crucial during dengue virus infection and progression to severe dengue. This study investigates the role of MBL2 genetic variants and levels of MBL in serum and complement proteins in Vietnamese dengue patients. MBL2 geno