Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Louis C. Tan"'
Autor:
Wing Lok Au, Louis C. Tan, Kumar M. Prakash, Y.-Y. Ng, Jianjun Liu, H.-K. Kwok, Yi Zhao, Tatsushi Toda, Eng-King Tan, R. Pavanni, Wataru Satake, W.-T. Zhao
Publikováno v:
Neurology. 75:508-512
Objective: A genome-wide association study (GWAS) in the Japanese population identified 2 new Parkinson disease (PD) susceptibility loci on 1q32 (PARK16) (OMIM 613164) and BST1. We analyzed single nucleotide polymorphism (SNPs) located at the GWAS-li
Publikováno v:
Neurology. 71:1727-1732
Objectives: To assess the association of ATP13A2 gene mutation among patients with early onset Parkinson disease (EOPD, onset Methods: Among 771 subjects, we studied 182 patients with EOPD and familial PD and 589 matched controls from two cohorts of
The LRRK2 Gly2385Arg variant is associated with Parkinson's disease: genetic and functional evidence
Autor:
L. Sun, R. Pavanni, Eng-King Tan, Chin Song Lu, Jianjun Liu, Prasanna R. Kolatkar, Lisa Skipper, Yih Yuen, E. Chua, Vincenzo Bonifati, Yi Zhao, Meng-Cheong Wong, M. G. Tan, S. Tang, Louis C. Tan, Stephanie Fook-Chong, A. Di Fonzo
Publikováno v:
Human Genetics, 120(6), 857-863. Springer-Verlag
Evidence of LRRK2 haplotypes associated with Parkinson's disease (PD) risk was recently found in the Chinese population from Singapore, and a common LRRK2 missense variant, Gly2385Arg, was independently detected as a putative risk factor for PD in th
Autor:
Herty Liany, Jianjun Liu, Wing Lok Au, Jia Nee Foo, Kumar M. Prakash, Louis C. Tan, Eng-King Tan
Publikováno v:
Neurobiology of aging. 35(4)
Mutations in DNAJC13, DNAJC6 and DNAJC5 have been implicated in Parkinson's disease (PD). To determine if rare coding variants in these genes play a role in PD risk in the Chinese population, we sequenced all coding exons of the three genes in 99 ear
Autor:
H. Q. Lim, R. Li, Louis C. Tan, Wing Lok Au, Kumar M. Prakash, Yi Zhao, Dario C. Angeles, Yik Ying Teo, Yuen Yih, Eng-King Tan
Publikováno v:
Neurology. 73:1161-1162
Essential tremor (ET), a neurologic disorder characterized by postural and action tremor, is one of the most common adult-onset motor disorders.1,2 While linkage regions have been identified in Icelandic and North American families, the causative gen
Autor:
Yi Zhao, R. Pavanni, R. Li, Hui-Qin Lim, Kumar M. Prakash, Louis C. Tan, Michelle Tang, Eng-King Tan, Stephanie Fook-Chong, Yuen Yih
Publikováno v:
Human Genetics. 124:287-288
We showed that the frequency of a LRRK2 variant (c.4883G > C, R1628P) was higher in Parkinson’s disease (PD) compared to controls (8.4 vs. 3.4%, P = 0.046, OR 2.5, 95% CI 1.1–5.6). In the multivariate logistic regression (with adjustments made fo