Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jean-Baptiste Cazier"'
Autor:
Richard T. Bryan, Anke Wesselius, Nadezda Lipunova, Kar Keung Cheng, Frederik-Jan van Schooten, Jean-Baptiste Cazier, Maurice P. Zeegers
Publikováno v:
Translational Andrology and Urology, 9(3), 1329-1337. AME Publishing Company
Transl Androl Urol
Transl Androl Urol
BACKGROUND: Urinary bladder cancer (UBC) is one of few cancers with an established gene-environment interaction (GxE) with smoking. However, it is unknown whether the interaction with tobacco use is present non-muscle invasive bladder cancer (NMIBC)
Autor:
Lambertus A. Kiemeney, Nadezda Lipunova, Anke Wesselius, Jean-Baptiste Cazier, Maurice P. Zeegers, Kar Keung Cheng, Richard T. Bryan, Frederik J. van Schooten, Tessel E. Galesloot
Publikováno v:
European Urology Oncology, 2, 4, pp. 381-389
European Urology Oncology, 2, 381-389
European Urology Oncology, 2(4), 381-389. Elsevier
European Urology Oncology, 2, 381-389
European Urology Oncology, 2(4), 381-389. Elsevier
Background: Non-muscle-invasive bladder cancer (NMIBC) causes a considerable health burden due to the high recurrence and progression rates. Past studies have identified multiple candidate loci associated with NMIBC prognosis, albeit lacking validati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f901608959b06d5c0d3fb2dc4cedbe4
https://doi.org/10.1016/j.euo.2018.08.020
https://doi.org/10.1016/j.euo.2018.08.020
Autor:
Helene Larsen, Jean-Baptiste Cazier, Michael L. Frigge, Jeffrey R. Gulcher, Emma Bjarnadottir, Yu Z. Bagger, Augustine Kong, Unnur Styrkarsdottir, Margret S Sigurdardottir, Struan F.A. Grant, Kristján Jónasson, Kari Stefansson, Inga Reynisdottir, Ottar Rolfsson, Gunnar Sigurdsson, Vala Drofn Johannsdottir, Claus Christiansen
Publikováno v:
PLoS Biology
PLoS Biology, Vol 1, Iss 3, p E69 (2003)
PLoS Biology, Vol 1, Iss 3, p E69 (2003)
Osteoporotic fractures are a major cause of morbidity and mortality in ageing populations. Osteoporosis, defined as low bone mineral density (BMD) and associated fractures, have significant genetic components that are largely unknown. Linkage analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7326facaae92677efd03322adadc8307
https://doi.org/10.1371/journal.pbio.0000069
https://doi.org/10.1371/journal.pbio.0000069
Autor:
Lara Lipton, Amy Price, Enric Domingo, Trinidad Caldés, Gianluca Severi, Emma Jaeger, Sarah Fielding, Auli Karhu, José M. Ladero, Alan M. Pittman, David J. Kerr, Axel Walther, Mobshra Qureshi, Ian Tomlinson, Sergi Castellví-Bel, King Yip Cheng, Miguel de la Hoya, Wendy Wood, Emily L. Webb, John M. Luk, G Evans, Philip Twiss, Timothy Bishop, Hans Morreau, Steven Penegar, Pak C. Sham, Angel Carracedo, Melissa C. Southey, Eamonn R. Maher, Maria Chiara Di Bernardo, Sarah L. Spain, Julian Peto, Anneke Lucassen, Kari Hemminki, Lynn Martin, Richard Gray, Ian Chandler, Luis G. Carvajal-Carmona, Jean-Baptiste Cazier, Steven J. Lubbe, Kimberley Howarth, Richard S. Houlston, Graham G. Giles, Maggie Gorman, Kate Sullivan, Zoe Kemp, Pavel Vodicka, Judy W. C. Ho, Lauri A. Aaltonen, Clara Ruiz-Ponte, Jayaram Vijayakrishnan, Asta Försti, Huw Thomas, Alessio Naccarati, Peter Broderick, Juul T. Wijnen, Antoni Castells, Tom van Wezel, John L. Hopper, Iina Niittymäki, José A. G. Agúndez, Sari Tuupanen, Andrew Rowan, Ella Barclay
Publikováno v:
Human Molecular Genetics. 17:3720-3727
The common single-nucleotide polymorphism (SNP) rs3802842 at 11q23.1 has recently been reported to be associated with risk of colorectal cancer (CRC). To examine this association in detail we genotyped rs3802842 in eight independent case-control seri
Autor:
Christopher Allen, Manu Gupta, Tracy Chaplin, Gael Molloy, Rosemary E. Gale, David C. Linch, Bryan D. Young, Jean-Baptiste Cazier, Claude Chelala, Manoj Raghavan
Publikováno v:
Genes, Chromosomes and Cancer. 47:729-739
The acquisition of uniparental disomy (aUPD) in acute myeloid leukemia (AML) results in homozygosity for known gene mutations. Uncovering novel regions of aUPD has the potential to identify previously unknown mutational targets. We therefore aimed to
Autor:
Peter Humburg, Alexander Kanapin, Nayia Petousi, Andrew Wilkie, Julian Knight, Jenny Taylor, Jean-Baptiste Cazier, Stefano Lise, Gerton Lunter, Davis McCarthy, Celeste Bento, Holger Cario, Peter Robbins, Peter Ratcliffe
Publikováno v:
Haematologica. 99(10)
The ERYTHROPOIETIN (EPO) gene is regulated by the transcription factor Hypoxia Inducible Factor-α (HIF-α). In this pathway, Prolyl Hydroxylase Domain protein 2 (PHD2) hydroxylates two prolyl residues in HIF-α, which in turn promotes HIF-α degrada
Autor:
Jayaram Vijayakrishnan, Ella Barclay, Maggie Gorman, Julian Peto, Andrew Rowan, Peter Broderick, Richard S. Houlston, Zoe Kemp, Luis G. Carvajal-Carmona, Sarah L. Spain, Emily L. Webb, Enric Domingo, Ian Chandler, Kate Sullivan, Steven J. Lubbe, Alan M. Pittman, Kimberley Howarth, Elli Papaemmanuil, Lynn Martin, Richard Gray, Gabrielle S. Sellick, Oliver M. Sieber, Sarah Fielding, Wendy Wood, Emma Jaeger, David J. Kerr, Steven Penegar, Ian Tomlinson, Jean-Baptiste Cazier, Mobshra Qureshi, Ana Teixeira
Publikováno v:
Nature Genetics. 39:1315-1317
To identify risk variants for colorectal cancer (CRC), we conducted a genome-wide association study, genotyping 550,163 tag SNPs in 940 individuals with familial colorectal tumor (627 CRC, 313 advanced adenomas) and 965 controls. We evaluated selecte
Autor:
Rosa M. Xicola, Xavier Bessa, Xavier Llor, Juan Clofent, Luis G. Carvajal-Carmona, Angel Carracedo, Claire Palles, Rodrigo Jover, Montserrat Andreu, Ceres Fernandez-Rozadilla, Ian Tomlinson, Montserrat Baiget, Antoni Castells, Sergi Castellví-Bel, Jean-Baptiste Cazier, María Jesús Lamas, Dolors Gonzalez, Luis A. López-Fernández, Victor Moreno, Alejandro Brea-Fernández, Luis Bujanda, Clara Ruiz-Ponte, Anna Abulí
Publikováno v:
BMC genomics, vol 14, iss 1
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Recercat. Dipósit de la Recerca de Catalunya
BMC Genomics
BMC GENOMICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Dipòsit Digital de la UB
Universidad de Barcelona
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Recercat. Dipósit de la Recerca de Catalunya
BMC Genomics
BMC GENOMICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Dipòsit Digital de la UB
Universidad de Barcelona
Background: Colorectal cancer (CRC) is a disease of complex aetiology, with much of the expected inherited risk being due to several common low risk variants. Genome-Wide Association Studies (GWAS) have identified 20 CRC risk variants. Nevertheless,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf4bc4b6080228a9f39d00c529bc1b5
https://escholarship.org/uc/item/9z6163kh
https://escholarship.org/uc/item/9z6163kh
Autor:
Malcolm G. Dunlop, Richard S. Houlston, Ian Tomlinson, Christopher Holmes, Joanna L. Davies, Jean-Baptiste Cazier
Publikováno v:
Davies, J L, Cazier, J-B, Dunlop, M G, Houlston, R S, Tomlinson, I P & Holmes, C C 2012, ' A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data ', PLoS ONE, vol. 7, no. 12, ARTN e48687 . https://doi.org/10.1371/journal.pone.0048687
PLoS ONE, Vol 7, Iss 12, p e48687 (2012)
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e48687 (2012)
PLoS ONE
Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6132d73a1595ff118b423d86476560
https://www.pure.ed.ac.uk/ws/files/8232535/A_Novel_Test_for_Gene_Ancestry_Interactions_in_Genome_Wide_Association_Data.pdf
https://www.pure.ed.ac.uk/ws/files/8232535/A_Novel_Test_for_Gene_Ancestry_Interactions_in_Genome_Wide_Association_Data.pdf
Autor:
Dominique Gauguier, Pierre Zalloua, Francis Rousseau, Hana Sbeite, Daniel E. Platt, Antoine Abchee, Jihane Romanos, Danielle A. Badro, Ivo Gut, Michella Ghassibe-Sabbagh, Marc Haber, Angelique K. Salloum, Elie Chammas, Georges Khazen, Nabil Shasha, Jörg Hager, Jean-Baptiste Cazier, Bouchra Douaihy, Hamid el Bayeh, Sonia Youhanna, Raed Othman, Yoichiro Kamatani, Mark Lathrop, Diana Zelenika, Martin Farrall, Samer Kabbani
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38663 (2012)
PLoS ONE
PLoS ONE
The manifestation of coronary artery disease (CAD) follows a well-choreographed series of events that includes damage of arterial endothelial cells and deposition of lipids in the sub-endothelial layers. Genome-wide association studies (GWAS) of mult