Zobrazeno 1 - 10
of 36
pro vyhledávání: '"D. C. Rao"'
Autor:
Yun Ju Sung, W. James Gauderman, Ingrid B. Borecki, Thomas W. Winkler, D. C. Rao, Patricia B. Munroe, Bruce M. Psaty, Karen Schwander, Kenneth Rice, L. Adrienne Cupples
Publikováno v:
Circulation. Cardiovascular genetics. 10(3)
Background— Several consortia have pursued genome-wide association studies for identifying novel genetic loci for blood pressure, lipids, hypertension, etc. They demonstrated the power of collaborative research through meta-analysis of study-specif
Autor:
Treva Rice, Nadine Spielmann, D. C. Rao, James S. Skinner, Tuomo Rankinen, Arthur S. Leon, Claude Bouchard
Publikováno v:
Physiological Genomics. 31:25-31
Associations between cholesteryl ester transfer protein (CETP) polymorphisms and high-density lipoprotein cholesterol (HDL-c) levels before and after 20 wk of endurance training were investigated in the HERITAGE Family Study. Plasma HDL-c, HDL2-c, HD
Autor:
Jacob, Basson, Yun Ju, Sung, Lisa de Las, Fuentes, Karen, Schwander, L Adrienne, Cupples, D C, Rao
Publikováno v:
Genetic epidemiology. 39(6)
Genetic variation accounts for approximately 30% of blood pressure (BP) variability but most of that variability has not been attributed to specific variants. Interactions between genes and BP-associated factors may explain some "missing heritability
Autor:
Jack H. Wilmore, James S. Skinner, Arthur S. Leon, Y.A. Kesäniemi, Claude Bouchard, Olavi Ukkola, Tuomo Rankinen, Timo A. Lakka, D. C. Rao
Publikováno v:
Obesity Research. 13:829-834
Protein tyrosine phosphatase 1B (PTPN1) affects the regulation of insulin signaling and energy metabolism. We studied whether polymorphisms in the PTPN1 gene impact body fat distribution in the HERITAGE Family Study cohort in 502 white and 276 black
Autor:
D. C. Rao, Luc Djoussé, Michèle M. Sale, B. I. Freedman, M. A. Province, Stephanie R Beck, James S. Pankow, Y. D.I. Chen, Stephen S. Rich, Cora E. Lewis, Gerardo Heiss
Publikováno v:
Diabetologia. 48:661-668
The heritability of fasting serum insulin and glucose concentrations in non-diabetic members of multiplex hypertensive families is unknown.We calculated the familial aggregation of fasting serum glucose and insulin concentrations and performed a geno
Autor:
Yohan Bossé, Jean-Pierre Després, D. C. Rao, Yvon C. Chagnon, Treva Rice, Louis Pérusse, Marie-Claude Vohl, Claude Bouchard, Benoît Lamarche
Publikováno v:
Circulation. 107:2361-2368
Background— Several lines of evidence suggest that small dense LDL particles are associated with the risk of coronary heart disease. Heritability and segregation studies suggest that LDL particle size is characterized by a large genetic contributio
Autor:
Christophe Garenc, Jack H. Wilmore, Tuomo Rankinen, Jacques Gagnon, James S. Skinner, D. C. Rao, Louis Pérusse, Arthur S. Leon, Claude Bouchard
Publikováno v:
Obesity Research. 9:337-341
Objective: To investigate the association between the Trp64Arg polymorphism of the β3-adrenergic receptor gene and changes in body composition in response to endurance training. Research Methods and Procedures: Adult sedentary white and black subjec
Autor:
D. C. Rao, Yvon C. Chagnon, Treva Rice, Louis Pérusse, James S. Skinner, Jack H. Wilmore, Tuomo Rankinen, Jacques Gagnon, Claude Bouchard, Arthur S. Leon
Publikováno v:
Scopus-Elsevier
ResearcherID
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Abstract —Endothelium-dependent vasodilation is a mechanism that may affect blood pressure response to endurance training. Because NO plays a central role in this process, the endothelial NO synthase gene is a good candidate for the regulation of e
Autor:
Jack H. Wilmore, Treva Rice, Louis Pérusse, Jacques Gagnon, James S. Skinner, Michael A. Province, D. C. Rao, Claude Bouchard, E. Daw, Arthur S. Leon
Publikováno v:
Medicine & Science in Sports & Exercise. 30:252-258
This study investigates the familial resemblance of maximal oxygen uptake (VO2max) based on data from 86 nuclear families of Caucasian descent participating in the HERITAGE Family Study. In the current study, VO2max was measured twice on a cycle ergo
Autor:
D. C. Rao, Michael A. Province, Aldi T. Kraja, Ulrich Broeckel, Heather A. Lawson, Lisa de las Fuentes, Ingrid B. Borecki, Steven C. Hunt, James M. Cheverud, Donna K. Arnett
Publikováno v:
Metabolism: clinical and experimental. 61(8)
Identifying metabolic syndrome (MetS) genes is important for novel drug development and health care. This study extends the findings on human chromosome 3p26-25 for an identified obesity–insulin factor QTL, with an LOD score above 3. A focused asso