Zobrazeno 81 - 90
of 100
pro vyhledávání: '"Yik Ying Teo"'
Autor:
Tin Aung, Xueling Sim, Chen Suo, Mark Seielstad, Terri L. Young, Kee Seng Chia, Liang Kee Goh, Xin Zhou, Wan Ting Tay, Yik Ying Teo, Yi-Ju Li, E-Shyong Tai, Eranga N. Vithana, Rick Twee-Hee Ong, Jianjun Liu, Seang-Mei Saw, Ching-Yu Cheng, Tien Yin Wong, Chiea Chuen Khor, Belinda K. Cornes, Qiao Fan, Mohammad Kamran Ikram
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002402 (2011)
PLoS genetics, vol 7, iss 12
PLoS Genetics
PLoS Genetics, 7(12):e1002402. Public Library of Science
PLoS genetics, vol 7, iss 12
PLoS Genetics
PLoS Genetics, 7(12):e1002402. Public Library of Science
Corneal astigmatism refers to refractive abnormalities and irregularities in the curvature of the cornea, and this interferes with light being accurately focused at a single point in the eye. This ametropic condition is highly prevalent, influences v
Autor:
Nguyen Thi Hong Tham, Dennis E.K. Tan, Rick Twee-Hee Ong, Tran Nguyen Bich Chau, Mai Ngoc Lanh, Ta Van Tram, Hoang Truong Long, Jeremy Farrar, Bridget Wills, Nguyen Minh Tuan, Nguyen Minh Nguyet, Tran Thi Gan, Nguyen Thi Nguyet Binh, Tran Thi Nhu Thuy, Sarah J. Dunstan, Martin L. Hibberd, Cameron P. Simmons, Nguyen Van Vinh Chau, Nguyen Trong Hieu, Sonia Davila, Junxiong Pang, Yik Ying Teo, Le Bich Lien, Le Trung Tri, Anavaj Sakuntabhai, Chiea Chuen Khor
Publikováno v:
Nature Genetics
Nature Genetics, 2011, 43 (11), pp.1139-1141. ⟨10.1038/ng.960⟩
Nature Genetics, Nature Publishing Group, 2011, 43 (11), pp.1139-1141. ⟨10.1038/ng.960⟩
Nature genetics
Nature Genetics, 2011, 43 (11), pp.1139-1141. ⟨10.1038/ng.960⟩
Nature Genetics, Nature Publishing Group, 2011, 43 (11), pp.1139-1141. ⟨10.1038/ng.960⟩
Nature genetics
Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam. Replication of the most
Autor:
Asif Rasheed, Prasad Katulanda, Maria Samuel, Junbin Liang, Kee Seng Chia, E. Shyong Tai, Xinzhong Li, Chiea Chuen Khor, Mark I. McCarthy, Åsa K. Hedman, Zafar I. Hydrie, Muhammed Islam, Robin Young, Mingyu Yang, John Danesh, James Scott, Elin Grundberg, Panos Deloukas, Inga Prokopenko, Alexandra C. Nica, Simon D. Rees, Paul Zimmet, Mark Seielstad, Manickam Chidambaram, A. Samad Shera, David R. Matthews, Xueling Sim, Norihiro Kato, Philippe Froguel, Venkatesan Radha, Timothy M. Frayling, Nabi Shah, Weihua Zhang, Jeremy B M Jowett, Danish Saleheen, MuTHER, Joban Sehmi, Janani Pinidiyapathirage, Mark J. Caulfield, Tin Aung, Malene M. Kristensen, Neelam Hassanali, Gonçalo R. Abecasis, John C. Chambers, Fan Zhang, Paul Elliott, Anthony H. Barnett, Fumihiko Takeuchi, Jaspal S. Kooner, M. Ann Kelly, Ananda R. Wickremasinghe, Tien Yin Wong, Wei-Yen Lim, Latonya F. Been, Dharambir K. Sanghera, Samuel Liju, Sudhir Kowlessur, Kerrin S. Small, Yik Ying Teo, Andrew P. Morris, Debashish Das, Viswanathan Mohan, Antigone S. Dimas, Philippe M. Frossard, Jianjun Liu, Chen Suo, Abdul Basit, Tazeen H. Jafar
Publikováno v:
Nature genetics. 43(10)
We carried out a genome-wide association study of type-2 diabetes (T2D) in individuals of South Asian ancestry. Our discovery set included 5,561 individuals with T2D (cases) and 14,458 controls drawn from studies in London, Pakistan and Singapore. We
Publikováno v:
Investigative ophthalmologyvisual science. 52(9)
Statistics is an integral part of research in ophthalmology. The application of appropriate statistical strategies allows clinicians to realize the full potential in analyzing data from paired ocular measurements, longitudinal design, and genome-wide
Autor:
Yudi Pawitan, Kee Seng Chia, Agus Salim, Yik Ying Teo, Chee-Seng Ku, Xueling Sim, Shu Mei Teo, Nasheen Naidoo, Mark Seielstad
Publikováno v:
Journal of human genetics. 56(8)
Copy number variations can be identified using newer genotyping arrays with higher single nucleotide polymorphisms (SNPs) density and copy number probes accompanied by newer algorithms. McCarroll et al. (2008) applied these to the HapMap II samples a
Autor:
Nomdo M. Jansonius, Jie Jin Wang, Johannes R. Vingerling, Yik Ying Teo, Paul Mitchell, Cornelia M. van Duijn, Xueling Sim, Seang-Mei Saw, Yingfeng Zheng, Tin Aung, Renyi Wu, Kee Seng Chia, Mark Seielstad, Martin L. Hibberd, Raghavan Lavanya, E-Shyong Tai, Tien Yin Wong, Wishal D. Ramdas, André G. Uitterlinden, Wan Ting Tay, Fernando Rivadeneira, Caroline C W Klaver, Chiea Chuen Khor, Belinda K. Cornes, Eranga N. Vithana
Publikováno v:
Human Molecular Genetics, 20(9), 1864-1872. Oxford University Press
Damage to the optic nerve (e.g. from glaucoma) has an adverse and often irreversible impact on vision. Earlier studies have suggested that the size of the optic nerve head could be governed by hereditary factors. We conducted a genome-wide associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c74054d76425f7a7ee38b314d78ea5
https://research.rug.nl/en/publications/da55bd69-637d-4a84-b69f-5faf571c564f
https://research.rug.nl/en/publications/da55bd69-637d-4a84-b69f-5faf571c564f
Autor:
Chen Suo, Wan Ting Tay, Tien Yin Wong, Jianjun Liu, Mark Seielstad, Michael Boehnke, Rick Twee-Hee Ong, Yik Ying Teo, Daniel P.K. Ng, Kee Seng Chia, E-Shyong Tai, Xueling Sim
Publikováno v:
PLoS genetics, vol 7, iss 4
PLoS Genetics
PLoS Genetics, Vol 7, Iss 4, p e1001363 (2011)
PLoS Genetics
PLoS Genetics, Vol 7, Iss 4, p e1001363 (2011)
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genetic variants associated with type 2 diabetes mellitus (T2D), many of which encode proteins not previously suspected to be involved in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a448c2be28fafe19112526809acc444
https://escholarship.org/uc/item/1c41424c
https://escholarship.org/uc/item/1c41424c
Publikováno v:
Bioinformatics (Oxford, England). 27(6)
Motivation: Methods for detecting positive selection relied on finding evidence of long haplotypes to identify candidate regions under selection. However, these methods generally do not identify the length and form of the selected haplotype. Results:
Autor:
Yik-Ying Teo, Xueling Sim
Publikováno v:
Current opinion in lipidology. 21(2)
Genome-wide association studies across numerous populations have uncovered a remarkable number of loci implicated with lipid-related traits. The association signals at a number of these loci have been successfully replicated across multiple populatio
Publikováno v:
Nature reviews. Genetics. 11(2)
Medical research in Africa has yet to benefit from the advent of genome-wide association (GWA) analysis, partly because the genotyping tools and statistical methods that have been developed for European and Asian populations struggle to deal with the