Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Stringham, Heather M"'
Autor:
Brotman SM; Department of Genetics, The University of North Carolina, Chapel Hill, NC., Oravilahti A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Rosen JD; Department of Genetics, The University of North Carolina, Chapel Hill, NC., Alvarez M; Department of Human Genetics, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA., Heinonen S; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland., van der Kolk BW; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Fernandes Silva L; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Perrin HJ; Department of Genetics, The University of North Carolina, Chapel Hill, NC., Vadlamudi S; Department of Genetics, The University of North Carolina, Chapel Hill, NC., Pylant C; Department of Epidemiology, The University of North Carolina, Chapel Hill, NC., Deochand S; Department of Epidemiology, The University of North Carolina, Chapel Hill, NC., Basta PV; Department of Epidemiology, The University of North Carolina, Chapel Hill, NC., Valone JM; Department of Genetics, The University of North Carolina, Chapel Hill, NC.; UNC Neuroscience Center, The University of North Carolina, Chapel Hill, NC., Narain MN; Department of Genetics, The University of North Carolina, Chapel Hill, NC.; Curriculum of Toxicology and Environmental Medicine, The University of North Carolina, Chapel Hill, NC., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Love MI; Department of Genetics, The University of North Carolina, Chapel Hill, NC.; Department of Biostatistics, The University of North Carolina, Chapel Hill, NC., Pietiläinen KH; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HealthyWeightHub, Endocrinology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Pajukanta P; Department of Human Genetics, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA.; Institute for Precision Health, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Mohlke KL; Department of Genetics, The University of North Carolina, Chapel Hill, NC.
Publikováno v:
Diabetes [Diabetes] 2023 Nov 01; Vol. 72 (11), pp. 1707-1718.
Autor:
Kanoni S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Graham SE; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA., Wang Y; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, Boston, MA, 02118, USA., Surakka I; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA., Ramdas S; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Zhu X; Department of Statistics, The Pennsylvania State University, University Park, PA, USA.; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA.; VA Palo Alto Health Care Systems, Palo Alto, CA, USA.; Department of Statistics, Stanford University, Stanford, CA, USA., Clarke SL; VA Palo Alto Health Care Systems, Palo Alto, CA, USA.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Bhatti KF; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Vedantam S; Boston Children's Hospital, EndocrinologyBoston, MA, 02115, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Locke AE; McDonnell Genome Institute and Department of Medicine, Washington University, St. Louis, MO, 63108, USA., Marouli E; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Zajac GJM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Wu KH; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA., Ntalla I; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Hui Q; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Atlanta VA Health Care System, Decatur, GA, USA., Klarin D; VA Palo Alto Health Care Systems, Palo Alto, CA, USA.; Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Hilliard AT; VA Palo Alto Health Care Systems, Palo Alto, CA, USA., Wang Z; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Atlanta VA Health Care System, Decatur, GA, USA., Xue C; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA., Thorleifsson G; deCODE Genetics/Amgen, Inc. Sturlugata 8, Reykjavik, 102, Iceland., Helgadottir A; deCODE Genetics/Amgen, Inc. Sturlugata 8, Reykjavik, 102, Iceland., Gudbjartsson DF; deCODE Genetics/Amgen, Inc. Sturlugata 8, Reykjavik, 102, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Sæmundargötu 2, Reykjavik, 102, Iceland., Holm H; deCODE Genetics/Amgen, Inc. Sturlugata 8, Reykjavik, 102, Iceland., Olafsson I; Department of Clinical Biochemistry, Landspitali - National University Hospital of Iceland, Hringbraut, Reykjavik, 101, Iceland., Hwang MY; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungcheongbuk-Do, South Korea., Han S; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungcheongbuk-Do, South Korea., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Sakaue S; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kanai M; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Brumpton BM; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Rasheed H; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Division of Medicine and Laboratory Sciences, University of Oslo, Oslo, Norway., Havulinna AS; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland.; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Veturi Y; Department of Genetics, Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 19104, USA., Pacheco JA; Center for Genetic Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60618, USA., Rosenthal EA; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA., Lingren T; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Feng Q; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kullo IJ; Department of Cardiovascular Medicine and the Gonda Vascular Center, Mayo Clinic, Rochester, MN, USA., Narita A; Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan., Takayama J; Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan., Martin HC; Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK., Hunt KA; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Trivedi B; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Haessler J; Fred Hutchinson Cancer Center, Division of Public Health Sciences, Seattle, WA, 9810, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA., Bradford Y; Department of Genetics, Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 19104, USA., Miller JE; Department of Genetics, Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 19104, USA., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.; Usher Institute, The University of Edinburgh, Nine, Edinburgh Bioquarter, 9 Little France Road, Edinburgh, EH16 4UX, UK., Lin K; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Millwood IY; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Rasheed A; Center for Non-Communicable Diseases, Karachi, Sindh, Pakistan., Hindy G; Department of Population Medicine, Qatar University College of Medicine, QU Health, Doha, Qatar., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Zhao W; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA.; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Turman C; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA., Huang H; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Choudhury A; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Sengupta D; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Brown MR; Human Genetics Center, Department of Epidemiology, School of Public Health, Human Genetics, and Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK., Yu K; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Schmidt EM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Pandit A; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Yin X; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Zhao JH; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK., Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Jang HM; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungcheongbuk-Do, South Korea., Yoon K; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungcheongbuk-Do, South Korea., Medina-Gomez C; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Pitsillides A; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, Boston, MA, 02118, USA., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, the Netherlands., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Ji Y; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Gao Z; Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Haworth S; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, BS1 2LY, UK., Yousri NA; Department of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.; Department of Computer and Systems Engineering, Alexandria University, Alexandria, Egypt., Mitchell RE; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield Grove, Bristol, BS8 2BN, UK., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore., Aadahl M; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bjerregaard AA; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, 22903, USA., Hwu CM; Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan., Hung YJ; Institute of Preventive Medicine, National Defense Medical Center, Postbox 90048~700, Sanhsia Dist, New Taipei City, 237101, Taiwan., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Ramirez J; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.; Aragon Institute of Engineering Research, University of Zaragoza and Centro de Investigación Biomédica en Red - Bioingeniería, Biomateriales Y Nanomedicina, Spain., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kårhus LL; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK., Sabater-Lleal M; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Spain.; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Mauro P; Istituto Di Ricerca Genetica E Biomedica, Consiglio Nazionale Delle Ricerche, Rome, Italy., Matteo F; Istituto Di Ricerca Genetica E Biomedica, Consiglio Nazionale Delle Ricerche, Rome, Italy.; Dipartimento Di Scienze Biomediche, Università Degli Studi Di Sassari, Sardinia, Italy., McDaid AF; University Center for Primary Care and Public Health, University of Lausanne, Rte de Berne 113, 1010, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Marques-Vidal P; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Dept of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow, UK., Møllehave LT; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Munz M; Institute for Cardiogenetics, University of Lübeck, DZHK (German Research Centre for Cardiovascular Research), Partner Site Hamburg/Lübeck/Kiel, University Heart Center Lübeck, Lübeck and Charité - University Medicine Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin and Berlin Institute of Health, Institute for Dental and Craniofacial Sciences, Department of Periodontology and Synoptic Dentistry, Berlin, Germany., Zeng L; Deutsches Herzzentrum München, Klinik Für Herz- Und Kreislauferkrankungen, Technische Universität München, Munich, Germany.; Deutsches Zentrum Für Herz-Kreislauf-Forschung (DZHK) E.V., Partner Site Munich Heart Alliance, Munich, Germany., Huang J; Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China., Yang B; Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China., Poveda A; Lund University Diabetes Center, Lund University, Malmö, Sweden., Kurbasic A; Lund University Diabetes Center, Lund University, Malmö, Sweden., Lamina C; Institute of Genetic Epidemiology, Department of Genetics, Medical University of Innsbruck, Innsbruck, Austria.; German Chronic Kidney Disease Study, Berlin, Germany., Forer L; Institute of Genetic Epidemiology, Department of Genetics, Medical University of Innsbruck, Innsbruck, Austria.; German Chronic Kidney Disease Study, Berlin, Germany., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.; LIFE Research Centre for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Straße 27, 04103, Leipzig, Germany., Galesloot TE; Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Bradfield JP; Quantinuum Research LLC, Wayne, PA, 19087, USA., Ruotsalainen SE; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland., Daw E; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Zmuda JM; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA., Mitchell JS; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Via Galvani 31, 39100, Bolzano, Italy., Fuchsberger C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Via Galvani 31, 39100, Bolzano, Italy., Christensen H; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, USA., Vazquez-Moreno M; Unidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, SE1 9RT, UK., Christofidou P; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Benjamins JW; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Engmann J; Institute of Cardiovascular Sciences, University College London, Gower Street, London, WC1E 6BT, UK.; Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK., Tsao NL; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA., Verma A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Slieker RC; Amsterdam UMC, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, 1081HV, the Netherlands.; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, 2333ZA, The Netherlands., Lo KS; Montreal Heart Institute, Université de Montréal, 5000 Belanger Street, Montreal, PQ, H1T1C8, Canada., Zilhao NR; Icelandic Heart Association, 201, Kopavogur, Iceland., Le P; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, L5L 1C6, Canada., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, 68167, Mannheim, Germany.; SYNLAB MVZ Humangenetik Mannheim GmbH, 68163, Mannheim, Germany., Delgado GE; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, 68167, Mannheim, Germany., Huo S; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Ikeda DD; Biomedical Technology Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Tokushima, Japan., Iha H; Biomedical Technology Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Tokushima, Japan., Yang J; School of Life Sciences, Westlake University, Hangzhou, 310024, Zhejiang, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, 310024, Zhejiang, China.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Liu J; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Demirkan A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Section of Statistical Multi-Omics, Department of Clinical and Experimental Research, University of Surrey, Guildford, Surrey, UK., Leonard HL; Laboratory of Neurogenetics, National Institute On Aging, NIH, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Marten J; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland., Frank M; Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany., Schmidt B; Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany., Smyth LJ; Centre for Public Health, Queen's University of Belfast, Belfast, Northern Ireland., Cañadas-Garre M; Centre for Public Health, Queen's University of Belfast, Belfast, Northern Ireland.; Genomic Oncology Area, GENYO, Centre for Genomics and Oncological Research: Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain.; Hematology Department, Hospital Universitario Virgen de Las Nieves, Granada, Spain.; Instituto de Investigación Biosanitaria de Granada (Ibs.GRANADA), Granada, Spain., Wang C; Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Nakatochi M; Public Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, 461-8673, Japan., Wong A; MRC Unit for Lifelong Health and Ageing at UCL, 1-19 Torrington Place, London, WC1E 7HB, UK., Hutri-Kähönen N; Tampere Centre for Skills Training and Simulation, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore., Xia R; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Huerta-Chagoya A; CONACYT, Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán, Ciudad de Mexico, Mexico.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Departamento de Medicina Genómica Y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Coyoacán, 04510, Mexico City, Mexico., Fernandez-Lopez JC; Departamento de Genómica Computacional, Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Lyssenko V; Lund University Diabetes Center, Lund University, Malmö, Sweden.; Center for Diabetes Research, University of Bergen, Bergen, Norway., Nongmaithem SS; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India., Bayyana S; Genomic Research On Complex Diseases (GRC Group), CSIR-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India., Stringham HM; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Irvin MR; Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Oldmeadow C; Hunter Medical Research Institute, Newcastle, Australia., Kim HN; Medical Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, 03181, Korea.; Department of Clinical Research Design & Evaluation, SAIHST, Sungkyunkwan University, Seoul, 06355, Korea., Ryu S; Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, 04514, Korea.; Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, 03181, Korea., Timmers PRHJ; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland.; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Arbeeva L; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA., Dorajoo R; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Duke-NUS Medical School, Health Services and Systems Research, Singapore, 169857, Singapore., Lange LA; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, Anschutz Medical Campus, University of Colorado, Denver, Aurora, CO, 80045, USA., Prasad G; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110020, India.; Academy of Scientific and Innovative Research, CSIR-Human Resource Development Centre, Ghaziabad, Uttar Pradesh, India., Lorés-Motta L; Departments of Ophthalmology and Human Genetics, Radboud University Nijmegen Medical Center, Philips Van Leydenlaan 15, Nijmegen, 6525 EX, the Netherlands., Pauper M; Departments of Ophthalmology and Human Genetics, Radboud University Nijmegen Medical Center, Philips Van Leydenlaan 15, Nijmegen, 6525 EX, the Netherlands., Long J; Vanderbilt Epidemiology Center, Division of Epidemiology, Vanderbilt University Medical Center, Nashville, USA., Li X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Theusch E; Department of Pediatrics, University of California San Francisco, Oakland, CA, 94609, USA., Takeuchi F; National Center for Global Health and Medicine, Tokyo, 1628655, Japan., Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Biostatistics and Epidemiology, University of Massachusetts-Amherst, Amherst, MA, 01003, USA., Loukola A; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland., Bollepalli S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland., Warner SC; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Wang YX; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Lane, Chong Wen Men, Beijing, 100005, China., Wei WB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 1 Dong Jiao Min Xiang, Beijing, 100730, Dong Cheng District, China., Nutile T; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso' - CNR, Naples, Italy., Ruggiero D; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso' - CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Sung YJ; Division of Biostatistics, Washington University, St. Louis, MO, 63110, USA., Chen S; Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China., Liu F; Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China., Yang J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Kentistou KA; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Banas B; Dept of Nephrology, University Hospital Regensburg, Regensburg, Germany., Nardone GG; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Smith JA; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA.; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Hebbar P; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece.; Department of Clinical Epidemiology, Institute of Health Informatics, University College London, London, UK., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Lin M; Massachusetts General Hospital Cancer Center, Charlestown, MA, 02129, USA., Concas MP; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy., Vaccargiu S; Institute of Genetic and Biomedical Research, National Research Council of Italy, UOS of Sassari, Sassari, Italy., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, the Netherlands., Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Cade BE; Sleep Medicine and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02115, USA., van der Laan SW; Central Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Chitrala KN; Laboratory of Epidemiology and Population Sciences, National Institute On Aging, NIH, Baltimore, MD, 20892-9205, USA.; Department of Engineering Technology, University of Houston-Sugarland, Houston, TX, USA., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald and University Medicine Greifswald, Greifswald, Germany., Bentley AR; Center for Research On Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, 12 South Drive, Room 1025, Bethesda, MD, 20892, USA., Doumatey AP; Center for Research On Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, 12 South Drive, Room 1025, Bethesda, MD, 20892, USA., Adeyemo AA; Center for Research On Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, 12 South Drive, Room 1025, Bethesda, MD, 20892, USA., Lee JY; Oneomics. Co. Ltd. 2F, Soonchunhyang Mirai Medical Center 173, Buheuyng-Ro, Bucheon-Si Gyeonggi-Do, 14585, Korea., Petersen ERB; Department of Clinical Biochemistry and Immunology, Hospital of Southern Jutland, Kresten Philipsens Vej 15, 6200, Aabenraa, Denmark., Nielsen AA; Department of Clinical Biochemistry, Lillebaelt Hospital, Kolding, Denmark., Choi HS; Department of Biomedical Science, Hallym University, Chuncheon, 24252, Gangwon-Do, Korea., Nethander M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Freitag-Wolf S; Institute of Medical Informatics and Statistics, Kiel University, Kiel, Germany., Southam L; Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK.; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany., Rayner NW; Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Wang CA; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, NSW, 2308, Australia., Lin SY; Center for Geriatrics and Gerontology, Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan., Wang JS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Couture C; Department of Kinesiology, Université Laval, Québec, Canada., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, 33520, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33014, Tampere, Finland., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital, 33521, Tampere, Finland.; Department of Cardiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33014, Tampere, Finland., Cuellar-Partida G; University of Queensland Diamantina Institute, Translational Research Institute, Kent St, Woolloongabba, Brisbane, QLD, 4102, Australia., Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Medicine, Bornholms Hospital, Rønne, Denmark., Hidalgo B; Department of Epidemiology, Ryals School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Giannakopoulou O; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Cai Q; Vanderbilt Epidemiology Center, Division of Epidemiology, Vanderbilt University Medical Center, Nashville, USA., Obura MO; Amsterdam UMC, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, 1081HV, the Netherlands., van Setten J; Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Li X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA., Liang J; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA., Tang H; Department of Genetics, Stanford University School of Medicine Stanford, Palo Alto, CA, 94305, USA., Terzikhan N; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Shin JH; Department of Biomedical Science, Hallym University, Chuncheon, 24252, Gangwon-Do, Korea., Jackson RD; Division of Endocrinology, Ohio State University, Columbus, OH, 43210, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, 98195, USA., Martin LW; School of Medicine and Health Sciences, George Washington University, Washington, DC, 20037, USA., Chen Z; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Li L; Department of Epidemiology, School of Public Health, Peking University Health Science Center, Beijing, China., Kawaguchi T; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Thiery J; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.; Institute for Laboratory Medicine, University Hospital Leipzig, Paul-List-Strasse 13/15, 04103, Leipzig, Germany., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, USA., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute On Aging, NIH, Baltimore, MD, 20892-9205, USA., Li H; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Nalls MA; Center for Alzheimer's and Related Dementias, NIH, Bethesda, MD, USA.; Data Tecnica International, Washington, DC, USA., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Ichihara S; Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, 329-0498, Japan., Wild SH; Centre for Population Health Sciences, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Jäger S; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany., Nabika T; Department of Functional Pathology, Shimane University School of Medicine, Izumo, 6938501, Japan., Al-Mulla F; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait., Niinikoski H; Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.; Department of Physiology, University of Turku, Turku, Finland., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Kolcic I; University of Split School of Medicine, Šoltanska 2, HR-21000, Split, Croatia., Kovacs P; University of Leipzig Medical Center, Liebigstr. 18, 04103, Medical Department III - Endocrinology, Nephrology, RheumatologyLeipzig, Germany., Giardoglou T; Department of Nutrition-Dietetics, Harokopio University, Eleftheriou Venizelou, 17676, Athens, Greece., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, 5650871, Japan.; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, 5650871, Japan., de Kleijn D; Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., de Borst GJ; Department of Vascular Surgery, Division of Surgical Specialties, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Kim EK; Corneal Dystrophy Research Institute, Yonsei University College of Medicine, Saevit Eye Hospital, SeoulIlsan, 03722, Korea., Adams HHH; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Dept of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Latin American Brain Health (BrainLat), Universidad Adolfo Ibáñez, Santiago, Chile., Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA., Asselbergs FW; Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Kraaijeveld AO; Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Beulens JWJ; Amsterdam UMC, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, 1081HV, the Netherlands.; Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, 3584CG, Utrecht, the Netherlands., Shu XO; Vanderbilt Epidemiology Center, Division of Epidemiology, Vanderbilt University Medical Center, Nashville, USA., Rallidis LS; Second Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mitchell P; Center for Vision Research, Department of Ophthalmology and The Westmead Institute, University of Sydney, Hawkesbury Rd, Sydney, NSW, 2145, Australia., Hewitt AW; School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, TAS, 7000, Australia.; Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC, 3002, Australia., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, 33521, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33014, Tampere, Finland., Pérusse L; Department of Kinesiology, Université Laval, Québec, Canada.; Centre Nutrition, Santé Et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Québec, Canada., Bouchard C; Pennington Biomedical Research Center, Baton Rouge, LA, 70808, USA., Tönjes A; University of Leipzig Medical Center, Liebigstr. 18, 04103, Medical Department III - Endocrinology, Nephrology, RheumatologyLeipzig, Germany., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Pennell CE; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, NSW, 2308, Australia., Mori TA; Discipline of Internal Medicine, Medical School, The University of Western Australia, Perth, WA, Australia., Lieb W; Institute of Epidemiology, Kiel University, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden., Mellström D; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Geriatric Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, 24252, Gangwon-Do, Korea., Lee H; Department of Internal Medicine, EwhaWomans University School of Medicine, Seoul, Korea., Yuan JM; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, 15232, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15232, USA., Koh WP; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117545, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, 117609, Singapore., Rhee SY; Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, 02447, Korea., Woo JT; Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, 02447, Korea., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Stark KJ; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Zimmermann ME; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald and University Medicine Greifswald, Greifswald, Germany., Evans MK; Laboratory of Epidemiology and Population Science, National Institute On Aging Intramural Research Program, NIH Biomedical Research Center, NIH 251 Bayview Blvd, Baltimore, MD, 21224, USA., Zonderman AB; Laboratory of Epidemiology and Population Science, National Institute On Aging Intramural Research Program, NIH Biomedical Research Center, NIH 251 Bayview Blvd, Baltimore, MD, 21224, USA., Polasek O; University of Split School of Medicine, Šoltanska 2, HR-21000, Split, Croatia.; Algebra University College, Ilica 242, Zagreb, Croatia., Pasterkamp G; Central Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Hoefer IE; Central Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Redline S; Sleep Medicine and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02115, USA., Pahkala K; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Physical Activity and Health, Paavo Nurmi Centre, Sports and Exercise Medicine Unit, University of Turku, Turku, Finland., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, the Netherlands., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, the Netherlands., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Bandinelli S; Local Health Unit Toscana Centro, Florence, Italy., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece., Thanaraj TA; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Kato N; National Center for Global Health and Medicine, Tokyo, 1628655, Japan., Schulze MB; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany., Girotto G; Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Strada Di Fiume 447, 34149, Trieste, Italy., Böger CA; Dept of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology, , Traunstein Hospital, Diabetology, RheumatologyTraunstein, Germany.; KfH Kidney Center Traunstein, Traunstein, Germany., Jung B; Dept of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology, , Traunstein Hospital, Diabetology, RheumatologyTraunstein, Germany.; KfH Kidney Center Traunstein, Traunstein, Germany., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., De Jager PL; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Neurology, Center for Translational and Systems Neuroimmunology, Columbia University Medical Center, New York, NY, USA., Lu X; Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China., Mamakou V; Medical School, National and Kapodistrian University Athens, 75 M. Assias Street, 115 27, Athens, Greece.; Dromokaiteio Psychiatric Hospital, 124 61, Athens, Greece., Brown M; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Ciullo M; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso' - CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Jonas JB; Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Lane, Chong Wen Men, Beijing, 100005, China.; Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Kutzerufer 1, 68167, Mannheim, Germany.; Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland.; Privatpraxis Prof Jonas Und Dr Panda-Jonas, Heidelberg, Germany., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Kaprio J; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland., Pajukanta P; Department of Human Genetics, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, USA., Tusié-Luna T; Unidad de Biología Molecular Y Medicina Genómica, Instituto de Investigaciones Biomédicas UNAM/ Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán, Mexico City, Mexico., Aguilar-Salinas CA; Departamento de Endocrinología Y Metabolismo, Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán, 14080, Mexico, Mexico., Adair LS; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA.; Carolina Population Center, University of North Carolina, Chapel Hill, NC, 27516, USA., Bechayda SA; USC-Office of Population Studies Foundation, University of San Carlos, 6000, Cebu City, Philippines.; Department of Anthropology, Sociology, and History, University of San Carlos, 6000, Cebu City, Philippines., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, 11010, Sri Lanka., Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, 11010, Sri Lanka., Krauss RM; Children's Hospital Oakland Research Institute, Oakland, CA, 94609, USA., Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Zheng W; Vanderbilt Epidemiology Center, Division of Epidemiology, Vanderbilt University Medical Center, Nashville, USA., Hollander AI; Departments of Ophthalmology and Human Genetics, Radboud University Nijmegen Medical Center, Philips Van Leydenlaan 15, Nijmegen, 6525 EX, the Netherlands., Bharadwaj D; Academy of Scientific and Innovative Research, CSIR-Human Resource Development Centre, Ghaziabad, Uttar Pradesh, India.; Systems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, 39216, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, 39216, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore and Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore, Singapore., Nelson AE; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Medicine, University of North Carolina, Chapel Hill, NC, USA., Golightly YM; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA.; Injury Prevention Research Center, University of North Carolina, Chapel Hill, NC, USA.; Division of Physical Therapy, University of North Carolina, Chapel Hill, NC, USA., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland.; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Penninx B; Amsterdam Public Health Research Institute, Amsterdam UMC, the Netherlands.; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Kim HL; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul, 07804, Korea., Attia J; Hunter Medical Research Institute, Newcastle, Australia.; Faculty of Health and Medicine, University of Newcastle, Callaghan, Australia., Scott RJ; Hunter Medical Research Institute, Newcastle, Australia.; Faculty of Health and Medicine, University of Newcastle, Callaghan, Australia., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, USA., Arnett DK; Office of the Provost, University of South Carolina, Columbia, SC, USA., Hunt SC; Department of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.; Department of Internal Medicine, University of Utah, Salt Lake City, Utah, 84132, USA., Walker M; Institute of Cellular Medicine (Diabetes), The Medical School, Newcastle University, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK., Koistinen HA; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, Helsinki University Hospital, University of Helsinki, Haartmaninkatu 4, P.O.Box 340, 00029, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, 00290, Helsinki, Finland., Chandak GR; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.; JSS Academy of Higher Education and Research, Mysuru, India., Mercader JM; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, 02115, USA., Costanzo MC; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jang D; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Burtt NP; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Villalpando CG; InstitutoNacional de Salud Publica Y Centro de Estudios en Diabetes, Cuernavaca, Mexico., Orozco L; Laboratorio de Inmunogenómica Y Enfermedades Metabólicas, Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Tai E; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, 119228, Singapore., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University, Washington, DC, 20052, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, 33520, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33014, Tampere, Finland., Chaturvedi N; MRC Unit for Lifelong Health and Ageing at UCL, 1-19 Torrington Place, London, WC1E 7HB, UK., Yokota M; Kurume University School of Medicine, Kurume, 830-0011, Japan., Liu J; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Reilly DF; Genetics, Merck Sharp & Dohme Corp., Kenilworth, NJ, 07033, USA., McKnight AJ; Centre for Public Health, Queen's University of Belfast, Belfast, Northern Ireland., Kee F; Centre for Public Health, Queen's University of Belfast, Belfast, Northern Ireland., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Palmer CNA; Population Health and Genomics, University of Dundee, Ninwells Hospital and Medical School, Dundee, DD1 9SY, UK., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, Scotland., Simonsick E; Intramural Research Program, National Institute On Aging, 3001 S. Hanover St., Baltimore, MD, 21225, USA., van Duijn CM; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Jin ZB; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, 100730, China.; The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China., Qu J; The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China., Hishigaki H; Biomedical Technology Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, Tokushima, Japan., Lin X; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., März W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, 68167, Mannheim, Germany.; Synlab Academy, SYNLAB Holding Deutschland GmbH, Mannheim and Augsburg, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Gudnason V; Icelandic Heart Association, 201, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Tardif JC; Montreal Heart Institute, Université de Montréal, 5000 Belanger Street, Montreal, PQ, H1T1C8, Canada., Lettre G; Montreal Heart Institute, Université de Montréal, 5000 Belanger Street, Montreal, PQ, H1T1C8, Canada., Hart LM'; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, 2333ZA, The Netherlands.; Department of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, 2333ZA, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, 1081HV, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam Cardiovascular Sciences, Amsterdam, 1081HV, the Netherlands., Elders PJM; Department of General Practice, Amsterdam UMC, Amsterdam, 1081HV, the Netherlands.; Amsterdam Public Health Research Institute, Health Behaviours and Chronic Diseases, Amsterdam, 1081HV, the Netherlands., Damrauer SM; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.; Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, 19104, USA., Kumari M; Institute of Social and Economic Research, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UK., Kivimaki M; Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Loos RJF; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Parra EJ; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, L5L 1C6, Canada., Cruz M; Unidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, 98101, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Via Galvani 31, 39100, Bolzano, Italy., Rotimi CN; Center for Research On Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, 12 South Drive, Room 1025, Bethesda, MD, 20892, USA., Christensen K; Danish Aging Research Center, University of Southern Denmark, Odense C, Denmark., Ripatti S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Widén E; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Tukholmankatu 8, 00014, Helsinki, Finland., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA., Grant SFA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Pediatrics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Kiemeney LALM; Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., de Graaf J; Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.; LIFE Research Centre for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Straße 27, 04103, Leipzig, Germany., Kronenberg F; Institute of Genetic Epidemiology, Department of Genetics, Medical University of Innsbruck, Innsbruck, Austria.; German Chronic Kidney Disease Study, Berlin, Germany., Gu D; Key Laboratory of Cardiovascular Epidemiology and Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.; School of Medicine, Southern University of Science and Technology, Shenzhen, China., Erdmann J; Institute for Cardiogenetics, University of Lübeck, DZHK (German Research Centre for Cardiovascular Research), Partner Site Hamburg/Lübeck/Kiel, and University Heart Center Lübeck, Lübeck, Germany., Schunkert H; Deutsches Herzzentrum München, Klinik Für Herz- Und Kreislauferkrankungen, Technische Universität München, Munich, Germany.; Deutsches Zentrum Für Herz-Kreislauf-Forschung (DZHK) E.V., Partner Site Munich Heart Alliance, Munich, Germany., Franks PW; Lund University Diabetes Center, Lund University, Malmö, Sweden., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Khera AV; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Verve Therapeutics, Cambridge, MA, USA., Männikkö M; Northern Finland Birth Cohorts, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter of Oulu, University of Oulu, Oulu, Finland., Kutalik Z; University Center for Primary Care and Public Health, University of Lausanne, Rte de Berne 113, 1010, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Francesco C; Institute for Genetic and Biomedical Research, Italian National Council of Research (IRGB CNR), Cagliari, Italy.; University of Sassari, Sassari, Italy., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., van Dijk KW; Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Watkins H; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, SW17 0RE, UK., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sever P; National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK., Poulter N; School of Public Health, Imperial College London, London, W12 7RH, UK., Chuang LM; Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, Taiwan., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Dantoft TM; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Karpe F; OCDEM, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, UK., Neville MJ; OCDEM, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, UK., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield Grove, Bristol, BS8 2BN, UK., Cheng CY; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Wong TY; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Khor CC; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Li H; Data Science, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore., Sabanayagam C; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Deutsches Zentrum Für Herz-Kreislauf-Forschung (DZHK) E.V., Partner Site Munich Heart Alliance, Munich, Germany.; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany., Hattersley AT; Medical School, University of Exeter, University of Exeter, Exeter, EX2 5DW, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, the Netherlands., Willemsen AHM; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, the Netherlands., Cupples L; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, Boston, MA, 02118, USA.; Framingham Heart Study, National Heart, Lung, and Blood Institute, US National Institutes of Health, Bethesda, MD, USA., van Meurs JBJ; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Ghanbari M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA.; Carolina Population Center, University of North Carolina, Chapel Hill, NC, 27516, USA., Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, 201203, China., Kim YJ; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungcheongbuk-Do, South Korea., Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin, Berlin, Germany., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK.; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM) and Klinikum Rechts Der Isar, TUM School of Medicine, Munich, Germany., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, 94305, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, 94305, USA., Abecasis G; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore.; Imperial College Healthcare NHS Trust, Imperial College London, London, W12 0HS, UK., Kooner JS; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UB1 3HW, UK.; School of Public Health, Imperial College London, London, W12 7RH, UK.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., de Vries PS; Human Genetics Center, Department of Epidemiology, School of Public Health, Human Genetics, and Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, School of Public Health, Human Genetics, and Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Hazelhurst S; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; School of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa., Ramsay M; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Daviglus M; Institute for Minority Health Research, University of Illinois College of Medicine, Chicago, IL, USA., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA., Martin NG; QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD, 4006, Australia., Whitfield JB; QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD, 4006, Australia., Abbas S; Center for Non-Communicable Diseases, Karachi, Sindh, Pakistan.; Faisalabad Institute of Cardiology, Faislabad, Pakistan., Saleheen D; Center for Non-Communicable Diseases, Karachi, Sindh, Pakistan.; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Cardiology, Columbia University Irving Medical Center, New York, NY, USA., Walters RG; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Big Data Institute, University of Oxford, Oxford, OX3 7LF, UK., Holmes MV; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals, Oxford, UK., Black C; Aberdeen Centre for Health Data Science,1:042 Polwarth Building School of Medicine, Medical Science and Nutrition University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK., Baras A; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Justice AE; Department of Population Health Sciences, Geisinger Health, Danville, PA, 17822, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Kooperberg C; Fred Hutchinson Cancer Center, Division of Public Health Sciences, Seattle, WA, 9810, USA., Tamiya G; Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan., Yamamoto M; Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan., van Heel DA; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Trembath RC; School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Wei WQ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Jarvik GP; Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington, Washington, USA., Namjou B; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA., Hayes MG; Center for Genetic Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60618, USA.; Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60618, USA.; Department of Anthropology, Northwestern University, Evanston, IL, 60208, USA., Ritchie MD; Department of Genetics, Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 19104, USA., Jousilahti P; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Public Health and Nursing, HUNT Research Centre, NTNU, Norwegian University of Science and Technology, 7600, Levanger, Norway.; Department of Research, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Public Health and Nursing, HUNT Research Centre, NTNU, Norwegian University of Science and Technology, 7600, Levanger, Norway.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Kubo M; RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.; Department of Genome Informatics, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan., Murakami Y; Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Kim BJ; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Chungcheongbuk-Do, South Korea., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc. Sturlugata 8, Reykjavik, 102, Iceland.; Faculty of Medicine, University of Iceland, Sæmundargötu 2, Reykjavik, 102, Iceland., Stefansson K; deCODE Genetics/Amgen, Inc. Sturlugata 8, Reykjavik, 102, Iceland.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester, UK., Zhang J; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA., Chen Y; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA., Ho YL; VA Boston Healthcare System, Boston, MA, USA., Lynch JA; VA Informatics and Computing Infrastructure, VA Salt Lake City Health Care System, Salt Lake City, UT, USA.; University of Massachusetts, Boston, MA, USA., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Tsao PS; VA Palo Alto Health Care Systems, Palo Alto, CA, USA.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Chang KM; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Cho K; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham Women's Hospital, Boston, MA, USA., O'Donnell CJ; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham Women's Hospital, Boston, MA, USA., Gaziano JM; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham Women's Hospital, Boston, MA, USA., Wilson PWF; Atlanta VA Health Care System, Decatur, GA, USA.; Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Hirschhorn JN; Boston Children's Hospital, EndocrinologyBoston, MA, 02115, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Departments of Pediatrics and Genetics, Harvard Medical School, Boston, MA, USA., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Medicine, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Atlanta VA Health Care System, Decatur, GA, USA., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester, UK., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Brown CD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Natarajan P; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Deloukas P; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Willer CJ; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA. cristen@umich.edu.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA. cristen@umich.edu.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48109, USA. cristen@umich.edu., Assimes TL; VA Palo Alto Health Care Systems, Palo Alto, CA, USA.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, Boston, MA, 02118, USA. gpeloso@bu.edu.
Publikováno v:
Genome biology [Genome Biol] 2022 Dec 27; Vol. 23 (1), pp. 268. Date of Electronic Publication: 2022 Dec 27.
Autor:
Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Bose D; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Kwon A; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Hanks SC; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Welch R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Oravilahti A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Fernandes Silva L; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Locke AE; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO 63108, USA., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Institute for Biomedicine, Eurac Research, Bolzano 39100, Italy., Service SK; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA., Erdos MR; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Bonnycastle LL; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland; Center for Medicine and Clinical Research, Kuopio University Hospital, Kuopio 70210, Finland., Stitziel NO; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO 63108, USA; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA; Department of Genetics, Washington University School of Medicine, St Louis, MO 63110, USA., Hall IM; Center for Genomic Health, Department of Genetics, Yale University, New Haven, CT 06510, USA., Morrison J; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Ripatti S; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki 00290, Finland; Department of Public Health, University of Helsinki, Helsinki 00014, Finland; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Palotie A; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki 00290, Finland; Department of Public Health, University of Helsinki, Helsinki 00014, Finland; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology, and Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA., Freimer NB; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA., Collins FS; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Fauman EB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, MA 02139, USA., Burant C; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland. Electronic address: markku.laakso@uef.fi., Wen X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA. Electronic address: xwen@umich.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2022 Oct 06; Vol. 109 (10), pp. 1727-1741. Date of Electronic Publication: 2022 Sep 01.
Autor:
Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. zhe.wang@mssm.edu., Emmerich A; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Pillon NJ; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Moore T; Division of Cardiology, Department of Medicine, University of California, Los Angeles, CA, USA., Hemerich D; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Mazzaferro E; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden., Broos S; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium.; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Physical Activity, Sports & Health Research Group, KU Leuven, Leuven, Belgium., Ahluwalia TS; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Bioinformatics Center, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Bartz TM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Chong M; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; GlaxoSmithKline, Cambridge, MA, USA., Berry D; Division of Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK., Dorajoo R; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore., Dueker ND; John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.; Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA., Kasbohm E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Institute of Mathematics and Computer Science, University of Greifswald, Greifswald, Germany., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Hall LM; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Haller T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.; MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK., Hillis DA; Genetics, Genomics, and Bioinformatics Graduate Program, University of California, Riverside, CA, USA., Huikari V; Institute of Health Sciences, University of Oulu, Oulu, Finland., Heard-Costa N; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Holzapfel C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany.; Institute for Nutritional Medicine, School of Medicine, Technical University of Munich, Munich, Germany., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Jørgensen AM; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kaakinen MA; Section of Statistical Multi-omics, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kerr KF; Department of Biostatistics, University of Washington, Seattle, WA, USA., Kim B; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea., Koolhaas CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Kutalik Z; University Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Lagou V; Wellcome Sanger Institute, Cambridge, UK., Lind PA; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Science, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia., Lorentzon M; Geriatric Medicine, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital Mölndal, Gothenburg, Sweden.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Mangino M; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK., Metzendorf C; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden., Monroe KR; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Pacolet A; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium., Pérusse L; Department of Kinesiology, Université Laval, Quebec, Quebec, Canada.; Centre Nutrition Santé et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada., Pool R; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Richmond RC; MRC Integrative Epidemiology Unit and Avon Longitudinal Study of Parents and Children, University of Bristol Medical School, Population Health Sciences and Avon Longitudinal Study of Parents and Children, University of Bristol, Bristol, UK., Rivera NV; Respiratory Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Rheumatology Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Center of Molecular Medicine (CMM), Karolinska Institutet, Stockholm, Sweden., Robiou-du-Pont S; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Schraut KE; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Schulz CA; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Nutrition and Food Sciences, Nutritional Epidemiology, University of Bonn, Bonn, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vanmunster M; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Exercise Physiology Research Group, KU Leuven, Leuven, Belgium., van Rooij FJA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Zhang X; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; School of Public Health, Department of Biostatistics, Shandong University, Jinan, China., Zhao JH; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Balkhiyarova Z; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Department of Clinical and Experimental Medicine, University of Surrey, Guilford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guilford, UK., Balslev-Harder MN; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Baumeister SE; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; University of Münster, Münster, Germany., Beilby J; Diagnostic Genomics, PathWest Laboratory Medicine WA, Perth, Western Australia, Australia., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, TX, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Brage S; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Bruinenberg M; Lifelines Cohort Study, Groningen, the Netherlands., Ekelund U; Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.; Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Cole JW; Vascular Neurology, Department of Neurology, University of Maryland School of Medicine and the Baltimore VAMC, Baltimore, MD, USA., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Cupples LA; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fernandez-Rhodes L; Department of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, University Park, PA, USA., Fohner AE; Department of Epidemiology, Institute of Public Health Genetics, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Franco OH; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Galesloot TE; Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands., Gordon SD; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hartman CA; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Heiss G; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Hui J; Diagnostic Genomics, PathWest Laboratory Medicine WA, Perth, Western Australia, Australia.; School of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.; Busselton Population Medical Research Institute, Busselton, Western Australia, Australia., Illig T; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Department of Human Genetics, Hannover Medical School, Hannover, Germany., Jago R; Centre for Exercise Nutrition & Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK., James A; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Western Australia, Perth, Australia., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Humanity Inc, Boston, MA, USA., Jung T; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea., Kähönen M; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Koh WP; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore, Singapore., Kolcic I; Department of Public Health, University of Split School of Medicine, Split, Croatia., Kraft PP; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institutes of Health, Baltimore, MD, USA., Li A; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Vidal PM; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Medland SE; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Psychology and Faculty of Medicine, University of Queensland, St Lucia, Queensland, Australia., Milaneschi Y; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands., Moscati A; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Musk B; Busselton Population Medical Research Institute, Busselton, Western Australia, Australia., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Peters A; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Power C; Division of Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Reedik M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rudan I; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Ryan K; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Sarzynski MA; Department of Exercise Science, University of South Carolina, Columbia, SC, USA., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Sidney S; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Siggeirsdottir K; Icelandic Heart Association, Kópavogur, Iceland., Smith AV; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Icelandic Heart Association, Kópavogur, Iceland., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Sonestedt E; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Strøm M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Faculty of Health Sciences, University of the Faroe Islands, Tórshavn, Faroe Islands., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Teo KK; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Thorand B; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Tönjes A; Department of Medicine, University of Leipzig, Leipzig, Germany., Tremblay A; Department of Kinesiology, Université Laval, Quebec, Quebec, Canada.; Centre Nutrition Santé et Société (NUTRISS), Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, Quebec, Canada., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Vangipurapu J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., van Schoor N; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, the Netherlands., Völker U; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Willemsen G; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Williams K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Wong Q; Department of Biostatistics, University of Washington, Seattle, WA, USA., Xu H; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Yuan JM; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Zillikens MC; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Zonderman AB; Laboratory of Epidemiology and Population Science, National Instiute on Aging, National Institutes of Health, Bethesda, MD, USA., Ameur A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Bandinelli S; Geriatric Unit, Azienda USL Toscana Centro, Florence, Italy., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Smith GD; MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK.; Population Health Science, Bristol Medical School, NIHR Bristol Biomedical Research Center, University of Bristol, Bristol, UK., de Geus EJC; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, the Netherlands., Deldicque L; Faculty of Movement and Rehabilitation Sciences, Institute of Neuroscience, UC Louvain, Louvain-la-Neuve, Belgium., Dörr M; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Evans MK; Laboratory of Epidemiology and Population Science, National Instiute on Aging, National Institutes of Health, Bethesda, MD, USA., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Fox C; Genetics and Pharmacogenomics (GpGx), Merck Research Labs, Boston, MA, USA., Garland T Jr; Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, Riverside, CA, USA., Gudnason V; Icelandic Heart Association, Kópavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Horta BL; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Hyppönen E; Australian Centre for Precision Health, Unit of Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Population, Policy and Practice, Great Ormond Street Hospital Institute for Child Health, University College London, London, UK., Jarvelin MR; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics and HPA-MRC Center, School of Public Health, Imperial College London, London, UK., Johnson WC; Department of Biostatistics, University of Washington, Seattle, WA, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kiemeney LA; Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Department of Clinical Chemistry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Martin NG; Mental Health and Neuroscience Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Melbye M; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; K.G.Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Center for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Meyre D; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Pare G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Park T; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.; Department of Statistics, Seoul National University, Seoul, South Korea., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Polasek O; University of Split School of Medicine, Split, Croatia., Prokopenko I; Department of Clinical and Experimental Medicine, University of Surrey, Guilford, UK.; People-Centred Artificial Intelligence Institute, University of Surrey, Guilford, UK.; UMR 8199 - EGID, Institut Pasteur de Lille, CNRS, University of Lille, Lille, France., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Spector TD; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol Medical School, University of Bristol, Bristol, UK., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University, Washington, DC, USA., van der Velde N; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.; Section of Geriatrics, Department of Internal Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health, Aging and Later Life, Amsterdam, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Vollenweider P; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany., Voortman T; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Waeber G; Division of Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Wichmann HE; Institute of Epidemiology, Helmholtz Zentrum München -Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Munich, Germany., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Hevener AL; Division of Endocrinology, Department of Medicine, University of California, Los Angeles, CA, USA., Krook A; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Zierath JR; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Thomis MAI; Faculty of Movement and Rehabilitation Sciences, Department of Movement Sciences - Physical Activity, Sports & Health Research Group, KU Leuven, Leuven, Belgium., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoed MD; The Beijer Laboratory and Department of Immunology, Genetics and Pathology, Uppsala University and SciLifeLab, Uppsala, Sweden. marcel.den_hoed@igp.uu.se.
Publikováno v:
Nature genetics [Nat Genet] 2022 Sep; Vol. 54 (9), pp. 1332-1344. Date of Electronic Publication: 2022 Sep 07.
Autor:
Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Chan LS; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Bose D; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., VandeHaar P; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Locke AE; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.; Institute for Biomedicine, Eurac Research, Bolzano, 39100, Italy., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Welch R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Yu K; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Fernandes Silva L; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Service SK; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, 90024, USA., Zhang D; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA., Hector EC; Department of Statistics, North Carolina State University, Raleigh, NC, 27695, USA., Young E; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA., Ganel L; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA., Das I; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA., Abel H; Department of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA., Erdos MR; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Bonnycastle LL; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland.; Center for Medicine and Clinical Research, Kuopio University Hospital, Kuopio, 70210, Finland., Stitziel NO; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.; Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA., Hall IM; Center for Genomic Health, Department of Genetics, Yale University, New Haven, CT, 06510, USA., Wagner GR; Metabolon, Inc., Morrisville, NC, 27560, USA., Kang J; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Morrison J; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Burant CF; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA., Collins FS; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Ripatti S; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, 00290, Finland.; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland.; Broad Institute of MIT & Harvard, Cambridge, MA, 02142, USA., Palotie A; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, 00290, Finland.; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology, and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, 02114, USA., Freimer NB; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, 90024, USA., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Wen X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA., Fauman EB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, MA, 02139, USA. Eric.Fauman@pfizer.com., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland. markku.laakso@uef.fi., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA. boehnke@umich.edu.
Publikováno v:
Nature communications [Nat Commun] 2022 Mar 28; Vol. 13 (1), pp. 1644. Date of Electronic Publication: 2022 Mar 28.
Autor:
Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Broadaway KA; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Pan C; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Ko A; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., He A; Bristol-Myers Squibb, Pennington, NJ 08534, USA., Tilford C; Bristol-Myers Squibb, Pennington, NJ 08534, USA., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.; Center for Biomedicine, European Academy of Bolzano/Bozen, University of Lübeck, Bolzano/Bozen, Italy., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Narisu N; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Pajukanta P; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Lusis AJ; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Civelek M; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22904, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2019 Dec 15; Vol. 28 (24), pp. 4161-4172.
Autor:
Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Kim DS; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Stancáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Naj A; Department of Pathology and Laboratory Medicine, Penn Neurodegeneration Genomics Center, University of Pennsylvania, PA 19104, USA.; Departments of Biostatistics, and Epidemiology (DBE) and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, PA 19104, USA., Perry JRB; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Huyghe JR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Davis JP; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Welch RP; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Chines PS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Narisu N; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Kangas AJ; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland., Soininen P; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Ala-Korpela M; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Systems Epidemiology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.; Department of Epidemiology and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, School of Public Health and Preventive Medicine, The Alfred Hospital, Monash University, Melbourne, VIC, Australia., Gudnason V; Icelandic Heart Association and the Faculty of Medicine, University of Iceland, Kopavogur, Iceland., Musani SK; University of Mississippi Medical Center, Jackson, MS 39213, USA., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulu, Finland.; Biocenter Oulu, University of Oulu, 90014 Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Schellenberg GD; Department of Pathology and Laboratory Medicine, Penn Neurodegeneration Genomics Center, University of Pennsylvania, PA 19104, USA., Speliotes EK; Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2018 May 01; Vol. 27 (9), pp. 1664-1674.
Autor:
Yu Y; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Xia L; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Lee S; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Zhou X; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Stringham HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Mukherjee B; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA, bhramar@umich.edu.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA, bhramar@umich.edu.
Publikováno v:
Human heredity [Hum Hered] 2018; Vol. 83 (6), pp. 283-314. Date of Electronic Publication: 2019 May 27.
Autor:
Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Marullo L; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy., Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Department of Genetics, Stanford University, Stanford, CA., Kaakinen M; Department of Genomics of Common Disease, Imperial College London, London, U.K., Pervjakova N; Estonian Genome Center, University of Tartu, Tartu, Estonia., Pers TH; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Johnson AD; Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA., Eicher JD; Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K., Lee Y; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Ma C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Steinthorsdottir V; deCODE genetics, Amgen, Inc., Reykjavik, Iceland., Thorleifsson G; deCODE genetics, Amgen, Inc., Reykjavik, Iceland., Qi L; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Van Zuydam NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics and Biomedical Research Institute, Ninewells Hospital, University of Dundee, Dundee, U.K., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K., Chen H; Human Genetics Center and Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX.; Center for Precision Health, School Biomedical Informatics, and School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Almgren P; Lund University Diabetes Centre and Department of Clinical Sciences Malmö, University Hospital Scania, Lund University, Malmö, Sweden., Voight BF; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.; Munich Heart Alliance, German Centre for Cardiovascular Disease, Munich, Germany., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; Wellcome Trust Sanger Institute, Hinxton, U.K., Robertson N; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K., Karssen LC; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; PolyOmica, 's-Hertogenbosch, the Netherlands., van Leeuwen EM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Willems SM; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Kwan P; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Chanda P; High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, MD., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY., Dina C; l'institut du thorax, INSERM, CNRS, Centre Hospitalier Universitaire de Nantes, Université de Nantes, Nantes, France., Thuillier D; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Yengo L; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Jiang L; Department of Genomics of Common Disease, Imperial College London, London, U.K., Sparso T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kestler HA; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.; Institute of Medical Systems Biology, Ulm University, Ulm, Germany., Chheda H; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Eisele L; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Gustafsson S; Molecular Epidemiology, Department of Medical Sciences, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden.; Department for Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Benediktsson R; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Landspítali University Hospital, Reykjavik, Iceland., Hreidarsson AB; Landspítali University Hospital, Reykjavik, Iceland., Kong A; deCODE genetics, Amgen, Inc., Reykjavik, Iceland., Sigurðsson G; Landspítali University Hospital, Reykjavik, Iceland.; Icelandic Heart Association, Kópavogur, Iceland., Kerrison ND; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Liang L; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA., Meitinger T; Munich Heart Alliance, German Centre for Cardiovascular Disease, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Roden M; German Center for Diabetes Research, Neuherberg, Germany.; Department of Endocrinology and Diabetology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich-Heine University Düsseldorf, Düsseldorf, Germany., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Division of Genetics and Endocrinology, Boston Children's Hospital, Boston, MA., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Fox C; Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA.; Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Rybin D; Data Coordinating Center, Boston University School of Public Health, Boston, MA., Isomaa B; Folkhälsan Research Center, Helsinki, Finland.; Department of Social Services and Health Care, Jakobstad, Finland., Lyssenko V; Lund University Diabetes Centre and Department of Clinical Sciences Malmö, University Hospital Scania, Lund University, Malmö, Sweden., Tuomi T; Folkhälsan Research Center, Helsinki, Finland.; Department of Medicine, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Couper DJ; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC., Pankow JS; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Jørgensen T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL., van Dam RM; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA., Sun Q; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Edkins S; Wellcome Trust Sanger Institute, Hinxton, U.K., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; National Institute for Health Research Oxford Biomedical Research Centre, Churchill Hospital, Oxford, U.K., Perry JRB; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, U.K., Tajes-Fernandes J; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K., Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Bonnycastle LL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Chines PS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Endocrinology, Department of Medicine and Abdominal Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Helsinki, Finland., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Endocrinology, Department of Medicine and Abdominal Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Helsinki, Finland., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden., Mühleisen TW; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Baldassarre D; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Gertow K; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Humphries SE; Cardiovascular Genetics, BHF Laboratories, Institute Cardiovascular Sciences, University College London, London, U.K., Tremoli E; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Meyer J; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Steinbach G; Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany., Wennauer R; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Eriksson JG; Folkhälsan Research Center, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland., Mӓnnistö S; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Peltonen L; Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA., Tikkanen E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland., Charpentier G; Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France., Eury E; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Lobbens S; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Leander K; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., McLeod O; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Ruderfer D; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY., Blüher M; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Kovacs P; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Tonjes A; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Maruthur NM; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.; Division of General Internal Medicine, Department of Medicine, Johns Hopkins Bloomberg School of Medicine, Baltimore, MD.; The Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD., Scapoli C; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy., Erbel R; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Stumvoll M; IFB AdiposityDiseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Deloukas P; Wellcome Trust Sanger Institute, Hinxton, U.K.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University London, London, U.K., Donnelly PJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Department of Statistics, University of Oxford, Oxford, U.K., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Boehm BO; Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm, Germany.; Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, Singapore., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC., Tuomilehto J; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Barroso I; Wellcome Trust Sanger Institute, Hinxton, U.K.; University of Cambridge Metabolic Research Laboratories and National Institute for Health Research Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital Cambridge, Cambridge, U.K., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Ingelsson E; Molecular Epidemiology, Department of Medical Sciences, and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA., Lind L; Cardiovascular Epidemiology, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Broad Institute of MIT and Harvard, Cambridge, MA., Cauchi S; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Froguel P; Department of Genomics of Common Disease, Imperial College London, London, U.K.; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY., Balkau B; INSERM, CESP, UMR 1018, Villejuif, France.; University of Paris-Sud, UMR 1018, Villejuif, France., Boeing H; German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Franks PW; Lund University, Malmö, Sweden.; Umeå University, Umeå, Sweden., Barricarte Gurrea A; Navarra Public Health Institute, Pamplona, Spain.; Navarra Institute for Health Research, Pamplona, Spain.; CIBER Epidemiology and Public Health, Madrid, Spain., Palli D; Cancer Research and Prevention Institute, Florence, Italy., van der Schouw YT; University Medical Center Utrecht, Utrecht, the Netherlands., Altshuler D; Broad Institute of MIT and Harvard, Cambridge, MA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Department of Genetics, Harvard Medical School, Boston, MA.; Department of Molecular Biology, Harvard Medical School, Boston, MA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA., Groop LC; Lund University Diabetes Centre and Department of Clinical Sciences Malmö, University Hospital Scania, Lund University, Malmö, Sweden.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K., Sijbrands E; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative, Netherlands Consortium for Healthy Ageing and Center for Medical Systems Biology, Rotterdam, the Netherlands., Florez JC; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Diabetes Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA., Meigs JB; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; General Medicine Division, Massachusetts General Hospital, Boston, MA., Boerwinkle E; Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, TX.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Morris AD; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, U.K., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics and Biomedical Research Institute, Ninewells Hospital, University of Dundee, Dundee, U.K.; Cardiovascular and Diabetes Medicine, Biomedical Research Institute, Ninewells Hospital, University of Dundee, Dundee, U.K., Hu FB; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Thorsteinsdottir U; deCODE genetics, Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stefansson K; deCODE genetics, Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Dupuis J; Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Morris AP; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.; Department of Biostatistics, University of Liverpool, Liverpool, U.K.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, U.K., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI boehnke@umich.edu., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K. mark.mccarthy@drl.ox.ac.uk.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.; National Institute for Health Research Oxford Biomedical Research Centre, Churchill Hospital, Oxford, U.K., Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K. i.prokopenko@imperial.ac.uk.; Department of Genomics of Common Disease, Imperial College London, London, U.K.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K.
Publikováno v:
Diabetes [Diabetes] 2017 Nov; Vol. 66 (11), pp. 2888-2902. Date of Electronic Publication: 2017 May 31.
Autor:
Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Fisher VA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Young K; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Barata L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., Deng X; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Czajkowski J; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., Hadley D; Population Health Research Institute, St. George's, University of London, London, SW17 0RE, UK.; TransMed Systems, Inc., Cupertino, California 95014, USA., Ngwa JS; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore Maryland, USA., Ahluwalia TS; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Chu AY; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA., Lim E; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Perez J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Eicher JD; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, The Framingham Heart Study, Framingham, Massachusetts, USA., Kutalik Z; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss instititute of Bioinformatics., Xue L; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Renström F; Department of Biobank Research, Umeå University, Umeå, Sweden.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden., Wu J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Qi Q; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA., Ahmad S; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Alfred T; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3015GE, The Netherlands., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Bonnefond A; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Bragg J; Internal Medicine - Nephrology, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Cadby G; Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Australia., Chittani M; Department of Health Sciences, University of Milan,Via A. Di Rudiní, 8 20142, Milano, Italy., Coggeshall S; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Corre T; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss instititute of Bioinformatics., Direk N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Psychiatry, Dokuz Eylul University, Izmir, Turkey., Eriksson J; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Fischer K; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Gorski M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Neergaard Harder M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Horikoshi M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Huang T; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Epidemiology Domain, Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore., Huffman JE; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, The Framingham Heart Study, Framingham, Massachusetts, USA.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, FI-00271 Finland., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Kumari M; ISER, University of Essex, Colchester CO43SQ, UK.; Department of Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Lim U; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, London, UK., Manichaikul A; Center for Public Health Genomics and Biostatistics Section, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia 22903, USA., Marten J; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Middelberg RPS; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Pérusse L; Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Canada.; Institute of Nutrition and Functional Foods, Université Laval, Québec, Canada., Pervjakova N; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia., Sarti C; Department of Social and Health Care, City of Helsinki, Helsinki, Finland., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Stančáková A; Department of Medicine, Institute of Clinical Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore Maryland, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Germany., Trompet S; Department of Cardiology, Leiden University Medical Center, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands., van der Laan SW; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands., Vedantam SL; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands., Vink JM; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.; Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Zhang W; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Hua Zhao J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Zimmermann ME; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Zubair N; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Abecasis GR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Adair LS; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Afaq S; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Afzal U; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Bakker SJL; Department of Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Bartz TM; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington 98101, USA., Beilby J; Busselton Population Medical Research Institute, Nedlands, Western Australia 6009, Australia.; PathWest Laboratory Medicine of WA, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.; School of Pathology and Laboraty Medicine, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss instititute of Bioinformatics., Biffar R; Clinic for Prosthetic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Germany., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas, USA., Boerwinkle E; Human Genetics Center, The University of Texas Health Science Center, PO Box 20186, Houston, Texas 77225, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Bottinger E; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, USA., Braga D; Department of Health Sciences, University of Milan,Via A. Di Rudiní, 8 20142, Milano, Italy., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Ireland., Buyske S; Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.; Department of Statistics and Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA., Campbell H; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Chambers JC; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK.; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Imperial College Healthcare NHS Trust, London, UK., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Curran JE; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas, USA., de Borst GJ; Department of Vascular Surgery, Division of Surgical Specialties, UMC Utrecht, The Netherlands., de Craen AJM; Department of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands., de Geus EJC; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.; EMGO+ Institute Vrije Universiteit &Vrije Universiteit Medical Center., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Delgado GE; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., den Ruijter HM; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Eriksson AL; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Esko T; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Ford I; Robertson Centre for Biostatistics, University of Glasgow, UK., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, JMAAW15 Jamaica., Gertow K; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Gigante B; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Glorioso N; Hypertension and Related Disease Centre, AOU-University of Sassari., Gong J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research, D-85764 Neuherberg, Germany., Grammer TB; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Haitjema S; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., Hallmans G; Department of Public Health and Clinical Medicine, Section for Nutritional Research, Umeå University, Umeå, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA., Hartman CA; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hastie ND; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA., Hindorff L; Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA., Hocking LJ; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland., Hollensted M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Holmen OL; St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Germany., Jan Hottenga J; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Huang J; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Hung J; School of Medicine and Pharmacology, The University of Western Australia, 25 Stirling Hwy, Crawley, Western Australia 6009, Australia.; Department of Cardiovascular Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Hutri-Kähönen N; Department of Pediatrics, Tampere University Hospital, Tampere 33521, Finland.; Department of Pediatrics, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, 751 85, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.; Science for Life Laboratory, Uppsala University, Uppsala, 750 85, Sweden., James AL; Busselton Population Medical Research Institute, Nedlands, Western Australia 6009, Australia.; School of Medicine and Pharmacology, The University of Western Australia, 25 Stirling Hwy, Crawley, Western Australia 6009, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Jansson JO; Department of Physiology, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment &Health, School of Public Health, Imperial College London, UK.; Center for Life Course Epidemiology, Faculty of Medicine, University of OuluP.O.Box 5000, FI-90014, Finland.; Biocenter Oulu, University of Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Kajaanintie 50, P.O.Box 20, FI-90220, 90029 Oulu, Finland., Jhun MA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Juonala M; Department of Medicine, University of Turku, Turku 20520 Finland.; Division of Medicine, Turku University Hospital, Turku 20521, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland.; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Karlsson M; Clinical and Molecular Osteoporosis Research Unit, Department of Orthopedics and Clinical Sciences, Skåne University Hospital, Lund University, Malmö, Sweden., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, FI-00271 Finland.; Department of Medicine and Abdominal Center: Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki, FI-00029 Finland.; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, FI-00290 Finland., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Croatia., Kolovou G; Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Krämer BK; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Kvaløy K; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, 7600 Levanger, Norway., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA., Leander K; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Lee NR; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City 6000, Philippines., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 751 85, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford, Oxford OX3 7BN, UK., Linneberg A; Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lobbens S; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Loh M; Dept Epidemiology and Biostatistics, School of Public Health, Imperical College London, UK.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Luben R; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lubke G; Department of Psychology, University of Notre Dame, Notre Dame, USA., Ludolph-Donislawski A; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany., Lupoli S; Department of Health Sciences, University of Milan,Via A. Di Rudiní, 8 20142, Milano, Italy., Madden PAF; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Männikkö R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Marques-Vidal P; Department of Medicine, Internal Medicine, Lausanne university hospital (CHUV), Lausanne, Switzerland., Martin NG; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, JMAAW15 Jamaica., McKnight B; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington 98101, USA.; Program in Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA., Mellström D; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Montgomery GW; Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Musk AB; Busselton Population Medical Research Institute, Nedlands, Western Australia 6009, Australia.; School of Population Health, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Olden M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland.; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Scotland., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Pisinger C; Research Center for Prevention and Health, Glostrup Hospital, Glostrup Denmark.; Department of Public Health, Faculty of Health Sciences, University of Copenhagen, Denmark., Porteous DJ; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland.; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Rawal R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Rice T; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA.; Division of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA., Bien SA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Rudan I; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale Delle Ricerche (CNR), Cittadella Universitaria di Monserrato, 09042, Monserrato, Italy., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow, UK., Savonen K; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Schlessinger D; Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Scholtens S; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden., Siemelink MA; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands., Silbernagel G; Division of Angiology, Department of Internal Medicine, Medical University of Graz, Austria., Slagboom PE; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Staessen JA; Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Science , University of Leuven, Campus Sint Rafael, Kapucijnenvoer 35, Leuven; Belgium.; R&D VitaK Group, Maastricht University, Brains Unlimited Building, Oxfordlaan 55, Maastricht, The Netherlands., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, UK., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Taylor KD; Center for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor/UCLA Medical Center, Torrance, California, USA.; Department of Pediatrics, University of California Los Angeles, Los Angeles, California, USA., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research, D-85764 Neuherberg, Germany., Thuillier D; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France., Tuomilehto J; Research Division, Dasman Diabetes Institute, Dasman, Kuwait.; Department of Neurosciences and Preventive Medicine, Danube-University Krems, 3500 Krems, Austria.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Vandenput L; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Vohl MC; Institute of Nutrition and Functional Foods, Université Laval, Québec, Canada.; School of Nutrition, Université Laval, Québec, Canada., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Germany., Vonk JM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands., Waeber G; Department of Medicine, Internal Medicine, Lausanne university hospital (CHUV), Lausanne, Switzerland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Westendorp RGJ; Department of Public Health, and Center for Healthy Ageing, University of Copenhagen, Denmark., Wild S; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Willemsen G; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands., Wong A; MRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London, WC1B 5JU, UK., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Zillikens MC; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Baldassarre D; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Balkau B; Inserm U-1018, CESP, 94807 Villejuif cedex France., Bandinelli S; Geriatric Unit, Azienda USL Toscana centro, Florence Italy., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Bruinenberg M; Lifelines Cohort Study, PO Box 30001, 9700 RB Groningen, The Netherlands., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts USA.; Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, USA., Chen YD; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrance, California 90502, USA., Chines PS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA., Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale Delle Ricerche (CNR), Cittadella Universitaria di Monserrato, 09042, Monserrato, Italy.; Dipartimento di Scienze Biomediche, Universita' degli Studi di Sassari, Sassari, Italy., Cusi D; Sanipedia srl, Bresso (Milano), Italy and Institute of Biomedical Technologies National Centre of Research Segrate, Milano, Italy., Faire U; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore Maryland, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, SE-205 02 Malmö, Sweden.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Department of Public Health &Clinical Medicine, Umeå University, Umeå, Sweden., Froguel P; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199 - EGID, Lille, France.; Department of Genomics of Common Disease, Imperial College London, London, UK., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill North Carolina, 27516, USA., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Germany., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Haiman CA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, 90089, USA., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland., Hveem K; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, 7600 Levanger, Norway., Johnson AD; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, The Framingham Heart Study, Framingham, Massachusetts, USA., Wouter Jukema J; Department of Cardiology, Leiden University Medical Center, The Netherlands.; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Kivimaki M; Department of Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Kooner JS; Faculty of Med, National Heart &Lung Institute, Cardiovascular Science, Hammersmith Campus, Hammersmith Hospital, Hammersmith Campus, Imperial College London, UK.; Cardiology, Ealing Hospital NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Kuh D; MRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London, WC1B 5JU, UK., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA., März W; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Biostatistics, University of Liverpool, Liverpool L69 3GL, UK., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, South Australia, Australia., Pasterkamp G; Laboratory of Experimental Cardiology, Department of Cardiology, Division Heart &Lungs, UMC Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division Laboratories &Pharmacy, UMC Utrecht, The Netherlands., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research, D-85764 Neuherberg, Germany., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle Washington USA., Polasek O; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK.; Department of Public Health, Faculty of Medicine, University of Split, Croatia., Psaty BM; Department of Medicine, University of Washington, Seattle, Washington 98195, USA.; Department of Epidemiology, University of Washington, Seattle, Washington 98101, USA.; Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98101, USA., Qi L; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Smith BH; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, Scotland.; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD2 4RB, Scotland., Sørensen TIA; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Epidemiology (formerly Institute of Preventive Medicine), Bispebjerg and Frederiksberg Hospital (2000 Frederiksberg), The Capital Region, Copenhagen, Denmark.; MRC Integrative Epidemiology Unit, Bristol University, Bristol, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany., Tiemeier H; Department of Psychiatry Erasmus Medical Center, Rotterdam, The Netherlands., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., van der Harst P; Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Vestergaard H; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne university hospital (CHUV), Lausanne, Switzerland., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Whitfield JB; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.; Usher Institute for Population Health Sciences and Informatics, The University of Edinburgh, Scotland, UK., Tyrrell J; Genetics of Complex Traits, University of Exeter Medical School, RILD Building University of Exeter, Exeter, EX2 5DW, UK.; European Centre for Environment and Human Health, University of Exeter Medical School, The Knowledge Spa, Truro TR1 3HD, UK., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Barroso I; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Level 4, Institute of Metabolic Science Box 289 Addenbrooke's Hospital Cambridge CB2 OQQ, UK.; University of Cambridge Metabolic Research Laboratories, Level 4, Institute of Metabolic Science Box 289 Addenbrooke's Hospital Cambridge CB2 OQQ, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Fox CS; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA., Hirschhorn JN; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.; Department of Genetics, Harvard Medical School, Boston Massachusetts 02115, USA., Hunter DJ; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Strachan DP; Population Health Research Institute, St. George's, University of London, London, SW17 0RE, UK.; Division of Population Health Sciences and Education, St George's, University of London, London SW17 0RE, UK., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3015GE, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA). Leiden, The Netherlands.; Center for Medical Systems Biology, Leiden, The Netherlands., Heid IM; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg 85764, Germany., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Marchini J; Department of Statistics, University of Oxford, Oxford, UK., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK.; Mount Sinai School of Medicine, New York 10029, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, USA., Kilpeläinen TO; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK.; Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, 10029, USA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine; St. Louis, Missouri, 63108 USA., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; NHLBI Framingham Heart Study, Framingham, Massachusetts, 01702 USA.
Publikováno v:
Nature communications [Nat Commun] 2017 Apr 26; Vol. 8, pp. 14977. Date of Electronic Publication: 2017 Apr 26.