Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Rotter, Ji"'
Autor:
Jiang MZ; Department of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599, United States., Gaynor SM; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, United States.; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY 10591, United States., Li X; Department of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599, United States.; Department of Biostatistics, 135 Dauer Drive, 4115D McGavran-Greenberg Hall, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States., Van Buren E; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, United States., Stilp A; Department of Biostatistics, 4333 Brooklyn Ave NE, University of Washington, Seattle, WA 98105, United States., Buth E; Department of Biostatistics, 4333 Brooklyn Ave NE, University of Washington, Seattle, WA 98105, United States., Wang FF; Department of Biostatistics, 4333 Brooklyn Ave NE, University of Washington, Seattle, WA 98105, United States., Manansala R; Centre for Health Economics Research & Modelling Infectious Diseases (CHERMID), Vaccine & Infectious Disease Institute (VAXINFECTIO) WHO Collaborating Centre, University of Antwerp, Campus Drie Eiken - Building S; Universiteitsplein 1 2610 Antwerpen, Belgium., Gogarten SM; Department of Biostatistics, 4333 Brooklyn Ave NE, University of Washington, Seattle, WA 98105, United States., Li Z; School of Mathematics and Statistics, Northeast Normal University, 5268 Renmin Street, Changchun, JL 130024, China., Polfus LM; Advanced Analytics, Ambry Genetics, 1 Enterprise, Aliso Viejo, CA 92656, United States., Salimi S; Department of Epidemiology and Public Health, Division of Gerontology, University of Maryland School of Medicine, 655 W. Baltimore Street, Baltimore, MD 21201, United States., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, 4333 Brooklyn Ave NE, Box 359458, Seattle, WA 98195, United States., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, 420 Delaware Street SE, Minneapolis, MN 55455, United States., Yanek LR; Department of Medicine, General Internal Medicine, Johns Hopkins University School of Medicine, 1830 E Monument St Rm 8024, Baltimore, MD 21287, United States., Durda P; Department of Pathology & Laboratory Medicine, University of Vermont Larner College of Medicine, 360 South Park Drive, Colchester, VT 05446, United States., Tracy RP; Department of Pathology & Laboratory Medicine, University of Vermont Larner College of Medicine, 360 South Park Drive, Colchester, VT 05446, United States., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, 200 Jeanette Lancaster Way, Charlottesville, VA 22903, United States., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, United States., Mitchell BD; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, 670 W. Baltimore St., Baltimore, MD 21201, United States., Lewis JP; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, 670 W. Baltimore St., Baltimore, MD 21201, United States., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, 4333 Brooklyn Ave NE, Box 359458, Seattle, WA 98195, United States.; Departments of Epidemiology and Health Systems and Population Health, University of Washington, 4333 Brooklyn Ave NE, Seattle, WA 98101, United States., Pratte KA; Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States., Silverman EK; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, United States., Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, United States., Avery C; Department of Epidemiology, University of North Carolina at Chapel Hill, 137 East Franklin Street, Chapel Hill, NC 27599, United States., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, 137 East Franklin Street, Chapel Hill, NC 27599, United States., Mathias RA; Department of Medicine, Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Cir JHAAC Room 3B53, Baltimore, MD 21287, United States., Faraday N; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, United States., Lin H; Department of Medicine, University of Massachusetts Chan Medical School, 55 Lake Ave North, Worcester, MA 01655, United States., Wang B; Department of Medicine, University of Massachusetts Chan Medical School, 55 Lake Ave North, Worcester, MA 01655, United States., Carson AP; Department of Medicine, University of Mississippi Medical Center, 350 W. Woodrow Wilson Avenue, Suite 701, Jackson, MS 39213, United States., Norwood AF; Department of Medicine, University of Mississippi Medical Center, 350 W. Woodrow Wilson Avenue, Suite 701, Jackson, MS 39213, United States., Gibbs RA; Department of Molecular and Human Genetics, Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, 1100 Fairview Avenue N, Seattle, WA 98109, United States., Lundin J; Division of Public Health Sciences, Fred Hutchinson Cancer Center, 1100 Fairview Avenue N, Seattle, WA 98109, United States., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Center, 1100 Fairview Avenue N, Seattle, WA 98109, United States., Dupuis J; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 2001 McGill College Avenue, Montreal, QC H3A 1G1, Canada.; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, United States., Hou L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 N Lake Shore Drive, Chicago, IL 60611, United States., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, 1825 Pressler Street, Houston, TX 77030, United States., Benjamin EJ; Department of Medicine, Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, 72 East Newton Street, Boston, MA 02118, United States.; Department of Epidemiology, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, United States.; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mount Wayte Ave #2, Framingham, MA 01702, United States., Reiner AP; Department of Epidemiology, University of Washington, 4333 Brooklyn Ave NE, Seattle, WA 98105, United States., Bowler RP; Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, United States., Lin X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, United States., Auer PL; Division of Biostatistics, Institute for Health and Equity, and Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, United States., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599, United States.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2024 Aug 06; Vol. 33 (16), pp. 1429-1441.
Autor:
Kwak SH; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA., Hernandez-Cancela RB; Department of Biostatistics, Boston University School of Public Health, Boston, MA., DiCorpo DA; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Condon DE; Sanford Imagenetics, Sanford Health, Sioux Falls, SD., Merino J; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Wu P; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA., Yao J; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA., Guo X; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA., Ahmadizar F; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.; Department of Data Science and Biostatistics, Julius Global Health, University Medical Center Utrecht, Utrecht, the Netherlands., Meyer M; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO., Sincan M; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Mercader JM; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Lee S; Division of Vascular Surgery and Endovascular Therapy, Massachusetts General Hospital, Boston, MA., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA., Vy HMT; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Lin Z; Department of Biostatistics, University of Minnesota, Minneapolis, MN., Armstrong ND; Department of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL., Gu S; Department of Internal Medicine, Sanford Health, Sioux Falls, SD., Tsao NL; Corporal Michael J. Crescenz VA Medical Center and Department of Surgery, Perelman School of Medicine, Philadelphia, PA., Lange LA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO., Wang N; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Wiggins KL; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA., Trompet S; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Liu S; Department of Epidemiology, Brown University, Providence, RI., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Judy R; Corporal Michael J. Crescenz VA Medical Center and Department of Surgery, Perelman School of Medicine, Philadelphia, PA., Schroeder PH; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Hasbani NR; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX., Bos MM; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX., Jackson RD; Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Ohio State University, Columbus, OH., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA.; Department of Epidemiology, University of Washington, Seattle, WA., Manson JE; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Chaudhary NS; Department of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL., Carmichael LK; Department of Internal Medicine, Sanford Health, Sioux Falls, SD., Chen YI; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA., Taylor KD; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA., Ghanbari M; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., van Meurs J; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Pitsillides AN; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA.; Department of Epidemiology, University of Washington, Seattle, WA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands., Do R; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Park KS; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kavousi M; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA., Damrauer SM; Corporal Michael J. Crescenz VA Medical Center and Department of Surgery, Perelman School of Medicine, Philadelphia, PA.; Department of Genetics, Perelman School of Medicine, Philadelphia, PA., Hajek C; Department of Internal Medicine, Sanford Health, Sioux Falls, SD., Cho NH; Department of Preventive Medicine, Ajou University School of Medicine, Suwon, Korea., Irvin MR; Department of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN., Nadkarni GN; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY., Sladek R; Department of Medicine and Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA., Florez JC; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Chasman DI; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Heckbert SR; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA.; Department of Epidemiology, University of Washington, Seattle, WA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada., Malhotra R; Cardiovascular Research Center, Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA., Rotter JI; Department of Pediatrics, Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA., Meigs JB; Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Department of General Internal Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA.
Publikováno v:
Diabetes care [Diabetes Care] 2024 Jun 01; Vol. 47 (6), pp. 1042-1047.
Autor:
Smith JL; Department of Cardiovascular Medicine (J.L.S., O.D., I.J.K.), Mayo Clinic, Rochester, MN., Tcheandjieu C; Department of Epidemiology and Biostatistics, University of California San Francisco (C.T.).; Gladstone Institute of Data Science and Biotechnology, Gladstone Institute, San Francisco, CA (C.T.).; VA Palo Alto Health Care System (C.T., A.H., P.S.T., S.L.C.)., Dikilitas O; Department of Cardiovascular Medicine (J.L.S., O.D., I.J.K.), Mayo Clinic, Rochester, MN., Iyer K; Stanford University School of Medicine, Palo Alto, CA (K. Iyer, A.H.)., Miyazawa K; Riken Center for Integrative Medical Sciences, Yokohama City, Japan (K.M., K. Ito)., Hilliard A; VA Palo Alto Health Care System (C.T., A.H., P.S.T., S.L.C.).; Stanford University School of Medicine, Palo Alto, CA (K. Iyer, A.H.)., Lynch J; Salt Lake City VA Met Center, UT (J.L.)., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA (J.I.R., Y.-D.I.C.)., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA (J.I.R., Y.-D.I.C.)., Sheu WH; Institute of Molecular and Genomic Medicine, National Health Research Institute (W.H.-H.S.).; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Veterans General Hospital (W.H.-H.S.).; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan (W.H.-H.S.)., Chang KM; Corporal Michael J Crescenz VA Medical Center, Philadelphia, PA (K.-M.C.)., Kanoni S; Queen Mary University of London, Cambridge, United Kingdom (S.K.)., Tsao PS; VA Palo Alto Health Care System (C.T., A.H., P.S.T., S.L.C.).; Stanford University, Stanford, CA (P.S.T., S.L.C., T.L.A.)., Ito K; Riken Center for Integrative Medical Sciences, Yokohama City, Japan (K.M., K. Ito)., Kosel M; Department of Health Sciences Research, Mayo Clinic, Rochester, MN (M.K., D.J.S.)., Clarke SL; VA Palo Alto Health Care System (C.T., A.H., P.S.T., S.L.C.).; Stanford University, Stanford, CA (P.S.T., S.L.C., T.L.A.)., Schaid DJ; Department of Health Sciences Research, Mayo Clinic, Rochester, MN (M.K., D.J.S.)., Assimes TL; Stanford University, Stanford, CA (P.S.T., S.L.C., T.L.A.)., Kullo IJ; Department of Cardiovascular Medicine (J.L.S., O.D., I.J.K.), Mayo Clinic, Rochester, MN.
Publikováno v:
Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2024 Jun; Vol. 17 (3), pp. e004272. Date of Electronic Publication: 2024 Feb 21.
Autor:
Hrytsenko Y; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; CardioVascular Institute (CVI), Beth Israel Deaconess Medical Center, Boston, MA, USA., Shea B; CardioVascular Institute (CVI), Beth Israel Deaconess Medical Center, Boston, MA, USA., Elgart M; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Kurniansyah N; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Lyons G; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Morrison AC; Department of Epidemiology, School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, TX, USA., Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Haring B; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.; Department of Medicine III, Saarland University, Homburg, Saarland, Germany., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Psaty BM; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Health Systems and Population Health, University of Washington, Seattle, WA, USA., Jaeger BC; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Gu CC; The Center for Biostatistics and Data Science, Washington University, St. Louis, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Levy D; The Population Sciences Branch of the National Heart, Lung and Blood Institute, Bethesda, MD, USA.; The Framingham Heart Study, Framingham, MA, USA., Lloyd-Jones D; Department of Preventive Medicine, Northwestern University, Chicago, IL, USA., Choi E; Columbia Hypertension Laboratory, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Brody JA; Department of Medicine, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Rotter JI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Moll M; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; VA Boston Healthcare System, West Roxbury, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, USA., Fornage M; Department of Epidemiology, School of Public Health, Human Genetics Center, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Simon N; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Castaldi P; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Casanova R; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Chung RH; Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Taipei City, Taiwan., Kaplan R; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty for Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Redline S; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Kelly T; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., O'Connor T; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Health Equity and Population Health, University of Maryland School of Medicine, Baltimore, MD, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Kim W; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, USA., Guo X; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Ida Chen YD; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Sofer T; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. tsofer@bidmc.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. tsofer@bidmc.harvard.edu.; CardioVascular Institute (CVI), Beth Israel Deaconess Medical Center, Boston, MA, USA. tsofer@bidmc.harvard.edu.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. tsofer@bidmc.harvard.edu.; Center for Life Sciences CLS-934, 3 Blackfan St., Boston, MA, 02115, USA. tsofer@bidmc.harvard.edu.
Publikováno v:
Scientific reports [Sci Rep] 2024 May 30; Vol. 14 (1), pp. 12436. Date of Electronic Publication: 2024 May 30.
Autor:
Keener R; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Chhetri SB; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Connelly CJ; Department of Molecular Biology and Genetics, Johns Hopkins University, Baltimore, MD, USA., Taub MA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Conomos MP; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Weinstock J; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Ni B; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA., Strober B; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA., Aslibekyan S; University of Alabama at Birmingham, Birmingham, AL, USA., Auer PL; Division of Biostatistics, Institute for Health & Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Barwick L; LTRC Data Coordinating Center, The Emmes Company, LLC, Rockville, MD, USA., Becker LC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Bleecker ER; Department of Medicine, Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.; Division of Pharmacogenomics, University of Arizona, Tucson, AZ, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Cade BE; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA., Celedon JC; Division of Pediatric Pulmonary Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Chang YC; Department of Internal Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; The National Heart, Lung, and Blood Institute, Boston University's Framingham Heart Study, Framingham, MA, USA., Custer B; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA., Freedman BI; Internal Medicine - Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Gladwin MT; School of Medicine, University of Maryland, Baltimore, MD, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA, USA., Hou L; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Evanston, IL, USA., Irvin MR; Department of Epidemiology, University of Alabama Birmingham, Birmingham, AL, USA., Isasi CR; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Johnsen JM; Department of Medicine and Institute for Stem Cell & Regenerative Medicine, University of Washington, Seattle, WA, USA., Kenny EE; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Minster RL; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA., Naseri T; Naseri & Associates Public Health Consultancy Firm and Family Health Clinic, Apia, Samoa.; International Health Institute, School of Public Health, Brown University, Providence, RI, USA., Viali S; Oceania University of Medicine, Apia, Samoa.; School of Medicine, National University of Samoa, Apia, Samoa.; Department of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, CT, USA., Nekhai S; Center for Sickle Cell Disease and Department of Medicine, College of Medicine, Howard University, Washington DC, USA., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Telen MJ; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Wu B; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA., Yanek LR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yang IV; Departments of Biomedical Informatics, Medicine, and Epidemiology, University of Colorado, Boulder, CO, USA., Albert C; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular, Brigham and Women's Hospital, Boston, MA, USA., Arnett DK; Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, USA., Ashley-Koch AE; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Barnes KC; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Blackwell TW; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Burchard EG; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA., Chen Z; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Darbar D; Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA., de Andrade M; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA., Ellinor PT; Cardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Fornage M; Institute of Molecular Medicine, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USA., Gelb BD; Mindich Child Health and Development Institute and Departments of Pediatrics and Genetics and Genomic Sciences, Icahn School of Medicine, New York, NY, USA., Gilliland FD; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., He J; Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Islam T; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., Kaab S; Department of Cardiology, University Hospital, LMU Munich, Munich, Germany., Kardia SLR; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kelly S; Vitalant Research Institute, San Francisco, CA, USA.; University of California San Francisco Benioff Children's Hospital, Oakland, CA, USA., Konkle BA; Department of Medicine, University of Washington, Seattle, WA, USA., Kumar R; Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; The Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Martinez FD; Asthma & Airway Disease Research Center, University of Arizona, Tucson, AZ, USA., McGarvey ST; Department of Epidemiology & International Health Institute, Brown University School of Public Health, Providence, RI, USA., Meyers DA; Department of Medicine, Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.; Division of Pharmacogenomics, University of Arizona, Tucson, AZ, USA., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Montgomery CG; Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Palmer ND; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Peralta JM; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Raby BA; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA., Redline S; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Roden D; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Ruczinski I; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Schwartz D; Departments of Medicine and Immunology, University of Colorado, Boulder, CO, USA., Sciurba F; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Shoemaker MB; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Sinner MF; Department of Cardiology, University Hospital, LMU Munich, Munich, Germany., Smith NL; Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Tiwari HK; Department of Biostatistics, University of Alabama Birmingham, Birmingham, AL, USA., Vasan RS; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Williams LK; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA., Zhang Y; Division of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Ziv E; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Arvanitis M; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA., Greider CW; Department of Molecular Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, USA.; University Professor Johns Hopkins University, Baltimore, MD, USA., Mathias RA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. rmathias@jhmi.edu., Battle A; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Malone Center for Engineering in Healthcare, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Data Science and AI Institute, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.
Publikováno v:
Nature communications [Nat Commun] 2024 May 24; Vol. 15 (1), pp. 4417. Date of Electronic Publication: 2024 May 24.
Autor:
Keaton JM; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kamali Z; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Xie T; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. a.vaez@umcg.nl.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran. a.vaez@umcg.nl., Williams A; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Goleva SB; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Ani A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; Department of Biomedical Research, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Ioannina, Greece., Hellwege JN; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Yengo L; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Young WJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Traylor M; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK., Giri A; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA., Zheng Z; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Zeng J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Chasman DI; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hwang SJ; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University, Boston, MA, USA., Kooner JS; National Heart and Lung Institute, Imperial College London, London, UK., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Attia JR; Faculty of Health and Medicine, University of Newcastle, New Lambton Heights, Newcastle, New South Wales, Australia., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kristiansson K; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Schmidt R; Department of Neurology/Medical University Graz, Graz, Austria., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; University of Lübeck, Lübeck, Germany., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; University of Lübeck, Lübeck, Germany., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Risch L; Faculty of Medical Sciences, Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; Department of Laboratory Medicine, Dr. Risch Anstalt, Vaduz, Liechtenstein., Gyllensten U; Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden., Riese H; Interdisciplinary Center Psychopathology and Emotional Regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Systems and Population Health, University of Washington, Seattle, WA, USA., Lu Y; Vanderbilt Genetic Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Sundström J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; Computational Medicine, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Giedraitis V; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Tuomilehto J; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Kutalik Z; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ripatti S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Trompet S; Department Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., van der Harst P; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ridker PM; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Giulianini F; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Watkins H; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Harris SE; Lothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK., Deary IJ; Lothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Heart Institute, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Campbell A; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK.; Usher Institute, University of Edinburgh, Edinburgh, UK., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Scott LJ; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boutin T; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Mamasoula C; Population Health Sciences Institute, Newcastle University, Newcastle, UK., Järvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Lehrstuhl für Epidemiologie, Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie (IBE), Ludwig-Maximilians-Universität München, Neuherberg, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Italy., Hui J; Busselton Population Medical Research Institute, Perth, Western Australia, Australia.; School of Population and Global Health, The University of Western Australia, Nedlands, Western Australia, Australia., Knekt P; Population Health Unit, Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Enroth S; Department of Immunology, Genetics, and Pathology, Biomedical Center, Science for Life Laboratory (SciLifeLab) Uppsala, Uppsala University, Uppsala, Sweden., De Borst MH; Department of Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Polašek O; University of Split School of Medicine, Split, Croatia.; Algebra University College, Zagreb, Croatia., Concas MP; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Catamo E; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Cocca M; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Spedicati B; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Waldenberger M; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Strachan DP; Population Health Sciences Institute St George's, University of London, London, UK., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Dörr M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Kopavogur, Iceland., Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK., Ruggiero D; IRCCS Neuromed, Pozzilli, Italy.; Institute of Genetics and Biophysics - 'A. Buzzati-Traverso', National Research Council of Italy, Naples, Italy., Kolcic I; Algebra University College, Zagreb, Croatia.; Department of Public Health, University of Split School of Medicine, Split, Croatia., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Johnson AD; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; The Framingham Heart Study, Framingham, MA, USA., Newton-Cheh C; Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Brown MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Sever PJ; International Centre for Circulatory Health, Imperial College London, London, UK., Poulter N; School of Public Health, Imperial College London, London, UK., Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore., Elosua R; Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; CIBER Enfermedades Cardiovasculares (CIBERCV), Barcelona, Spain.; Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain., Siscovick D; New York Academy of Medicine, New York, NY, USA., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Institute of Genomics, University of Tartu, Tartu, Estonia., Strawbridge RJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.; Health Data Research UK, Glasgow, UK.; Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Hamsten A; Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Hottenga JJ; Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands., de Geus E; Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Centre, Amsterdam, the Netherlands., Morris AD; Data Science, University of Edinburgh, Edinburgh, UK.; Health Data Research UK, London, UK., Palmer CNA; Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Milaneschi Y; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Marten J; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Wright A; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Zeggini E; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany., Howson JMM; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., O'Donnell CJ; VA Boston Healthcare System, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Spector T; Department of Twin Research, King's College London, London, UK., Nalls MA; Center for Alzheimer's and Related Dementias, NIA/NINDS, NIH, Bethesda, MD, USA.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA.; DataTecnica LLC, Washington, DC, USA., Simonsick EM; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Liu Y; Division of Cardiology, Duke University School of Medicine, Durham, NC, USA., van Duijn CM; Nuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK., Danesh JN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Department of Human Genetics, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Menni C; Department of Twin Research and Genetic Epidemiology, London, UK., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Khaw KT; Department of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, UK., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.; VA Atlanta Healthcare System, Decatur, GA, USA., Wilson PWF; Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA.; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA., Cho K; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Denny JC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Levy D; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Edwards TL; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. todd.l.edwards@vumc.org., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2024 May; Vol. 56 (5), pp. 778-791. Date of Electronic Publication: 2024 Apr 30.
Autor:
Suzuki K; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK.; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan., Hatzikotoulas K; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. konstantinos.hatzikotoulas@helmholtz-munich.de., Southam L; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Taylor HJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Yin X; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Lorenz KM; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Mandla R; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Huerta-Chagoya A; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Melloni GEM; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kanoni S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Rayner NW; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Bocher O; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Arruda AL; Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Graduate School of Experimental Medicine, Technical University of Munich, Munich, Germany.; Munich School for Data Science, Helmholtz Munich, Neuherberg, Germany., Sonehara K; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Namba S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan., Lee SSK; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Preuss MH; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Petty LE; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Schroeder P; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Vanderwerff B; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Kals M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Bragg F; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London NorthWest Healthcare NHS Trust, London, UK., Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Kim YJ; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, South Korea., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Nano J; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lamri A; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada., Nakatochi M; Public Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan., Moon S; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, South Korea., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK., Lee JJ; Division of Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA, USA., Pan I; Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA., Taliun D; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Parra EJ; Department of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Hai Y; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Thorleifsson G; deCODE Genetics, Amgen, Reykjavik, Iceland., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sofer T; Department of Biostatistics, Harvard University, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard University, Boston, MA, USA., Wuttke M; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany., Sarnowski C; Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Nousome D; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands., Kwak SH; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea., Long J; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Sun M; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Tong L; Institute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA., Chen WM; Department of Public Health Sciences and Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Nongmaithem SS; Genomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands., Lim VJY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Tam CHT; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Chinese University of Hong Kong, Hong Kong, China., Joo YY; Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, South Korea.; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Prins BP; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Nicolas A; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Yanek LR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Kabagambe E; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Division of Academics, Ochsner Health, New Orleans, LA, USA., An P; Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA., Xiang AH; Department of Research and Evaluation, Division of Biostatistics Research, Kaiser Permanente of Southern California, Pasadena, CA, USA., Choi HS; Department of Biomedical Science, Hallym University, Chuncheon, South Korea., Cade BE; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Tan J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Broadaway KA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Williamson A; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK., Kamali Z; Department of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Cui J; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Thangam M; Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden., Adair LS; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Aguilar-Salinas CA; Unidad de Investigación en Enfermedades Metabólicas and Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Ahluwalia TS; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Bioinformatics Center, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Anand SS; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Bertoni A; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brandslund I; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark., Buchanan TA; Department of Medicine, Division of Endocrinology and Diabetes, Keck School of Medicine of USC, Los Angeles, CA, USA., Burant CF; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Hinxton, UK.; National Institute for Health and Care Research (NIHR) Blood and Transplant Unit (BTRU) in Donor Health and Behaviour, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Canouil M; Inserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France.; University of Lille, Lille, France., Chan JCN; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, Chinese University of Hong Kong, Hong Kong, China., Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Chee ML; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Chen J; Exeter Centre of Excellence in Diabetes (ExCEeD), Exeter Medical School, University of Exeter, Exeter, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Chen SH; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA., Chen YT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Chuang LM; Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan., Cushman M; Department of Medicine, University of Vermont, Colchester, VT, USA., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Hinxton, UK.; National Institute for Health and Care Research (NIHR) Blood and Transplant Unit (BTRU) in Donor Health and Behaviour, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Das SK; Section of Endocrinology and Metabolism, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Dedoussis G; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece., Dimitrov L; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Du S; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Duan Q; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Eckardt KU; Department of Nephrology and Medical Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Department of Nephrology and Hypertension, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Emery LS; Department of Biostatistics, University of Washington, Seattle, WA, USA., Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, USA., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Fischer K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Floyd JS; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Franco OH; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Freedman BI; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Genter P; Department of Medicine, Division of Endocrinology and Metabolism, Lundquist Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Gerstein HC; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Giedraitis V; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., González-Villalpando C; Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Mexico City, Mexico., González-Villalpando ME; Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Mexico City, Mexico., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gross M; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Guare LA; Genomics and Computational Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Hackinger S; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Hakaste L; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland., Han S; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, South Korea., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Herder C; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Department of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Horikoshi M; Laboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Howard AG; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hsueh W; Department of Internal Medicine, Diabetes and Metabolism Research Center, Ohio State University Wexner Medical Center, Columbus, OH, USA., Huang M; Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.; Center for Global Cardiometabolic Health, Brown University, Providence, RI, USA., Huang W; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China., Hung YJ; Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan Branch, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan., Hwang MY; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea., Hwu CM; Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Ichihara S; Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan., Ikram MA; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Ingelsson M; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Islam MT; University of Chicago Research Bangladesh, Dhaka, Bangladesh., Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Jang HM; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea., Jasmine F; Institute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA., Jiang G; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Chinese University of Hong Kong, Hong Kong, China., Jonas JB; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland., Jørgensen T; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark., Kamanu FK; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kandeel FR; Department of Clinical Diabetes, Endocrinology and Metabolism, Department of Translational Research and Cellular Therapeutics, City of Hope, Duarte, CA, USA., Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Osaka, Japan.; Department of Geriatric and General Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan., Kaur V; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Kawaguchi T; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Keaton JM; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Kho AN; Division of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Health Information Partnerships, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Khor CC; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Kibriya MG; Institute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA., Kim DH; Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea., Kronenberg F; Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Läll K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lange LA; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Lee KM; VA Salt Lake City Health Care System, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA., Lee MS; Soochunhyang Institute of Medi-bio Science and Division of Endocrinology, Department of Internal Medicine, Soochunhyang University College of Medicine, Cheonan, South Korea.; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Lee NR; USC-Office of Population Studies Foundation, University of San Carlos, Cebu City, Philippines., Leong A; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.; Peking University Center for Public Health and Epidemic Preparedness and Response, Beijing, China., Li Y; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Ligthart S; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Lindgren CM; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu J; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Locke AE; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA.; Department of Medicine, Division of Genomics and Bioinformatics, Washington University School of Medicine, St Louis, MO, USA.; Regeneron Genetics Center, Tarrytown, NY, USA., Louie T; Department of Biostatistics, University of Washington, Seattle, WA, USA., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Luk AO; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.; Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Chinese University of Hong Kong, Hong Kong, China., Luo X; Department of Biostatistics and Data Science, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA., Lv J; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.; Peking University Center for Public Health and Epidemic Preparedness and Response, Beijing, China., Lynch JA; VA Salt Lake City Health Care System, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA., Lyssenko V; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Department of Clinical Science, Center for Diabetes Research, University of Bergen, Bergen, Norway., Maeda S; Laboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.; Division of Clinical Laboratory and Blood Transfusion, University of the Ryukyus Hospital, Nishihara, Japan., Mamakou V; Dromokaiteio Psychiatric Hospital, National and Kapodistrian University of Athens, Athens, Greece., Mansuri SR; Genomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Matsuda K; Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technical University Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Melander O; Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mo H; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Morris AD; Usher Institute to the Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Moura FA; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Nadler JL; Department of Medicine and Pharmacology, New York Medical College, Valhalla, NY, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA.; Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD, USA., Nayak U; Department of Public Health Sciences and Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Ntalla I; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Suita, Japan., Orozco L; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Patel SR; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Patil S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Pei P; Peking University Center for Public Health and Epidemic Preparedness and Response, Beijing, China., Pereira MA; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany., Pirie FJ; Department of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa., Polikowsky HG; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Porneala B; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Prasad G; Academy of Scientific and Innovative Research, CSIR-Human Resource Development Campus, Ghaziabad, India.; Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Reiner AP; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Roden M; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Department of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Rohde R; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Roll K; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Sandow K; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Sankareswaran A; Genomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sattar N; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK., Schönherr S; Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria., Shahriar M; Institute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA., Shen B; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Shi J; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China., Shin DM; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea., Shojima N; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., So WY; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, Chinese University of Hong Kong, Hong Kong, China., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Steinthorsdottir V; deCODE Genetics, Amgen, Reykjavik, Iceland., Stilp AM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Biostatistics, Epidemiology, and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.; Chair of Genetic Epidemiology, Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Thorand B; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Thorsteinsdottir U; deCODE Genetics, Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Tomlinson B; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.; Faculty of Medicine, Macau University of Science and Technology, Macau, China., Tran TC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Tsai FJ; Department of Medical Genetics and Medical Research, China Medical University Hospital, Taichung, Taiwan., Tuomilehto J; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.; National School of Public Health, Madrid, Spain.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tusie-Luna T; Unidad de Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Departamento de Medicina Genómica y Toxiología Ambiental, Instituto de Investigaciones Biomédicas, UNAM, Mexico City, Mexico., Udler MS; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Valladares-Salgado A; Unidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., van Klinken JB; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Chemistry, Laboratory of Genetic Metabolic Disease, Amsterdam University Medical Center, Amsterdam, The Netherlands., Varma R; Southern California Eye Institute, CHA Hollywood Presbyterian Hospital, Los Angeles, CA, USA., Wacher-Rodarte N; Unidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Wheeler E; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., van Dijk KW; 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Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.; Peking University Center for Public Health and Epidemic Preparedness and Response, Beijing, China., Yuan JM; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Yusuf S; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada., Zawistowski M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Zhang L; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Zheng W; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Raffel LJ; Department of Pediatrics, Division of Genetic and Genomic Medicine, UCI Irvine School of Medicine, Irvine, CA, USA., Igase M; Department of Anti-Aging Medicine, Ehime University Graduate School of Medicine, Touon, Japan., Ipp E; Department of Medicine, Division of Endocrinology and Metabolism, Lundquist Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, South Korea., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Province MA; Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA., Hanis CL; 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Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA., Yokota M; Kurume University School of Medicine, Kurume, Japan., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Engert JC; Department of Medicine, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Bonnefond A; Inserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France.; University of Lille, Lille, France.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Froguel P; Inserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France.; University of Lille, Lille, France.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Wilson JG; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Sheu WHH; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of Endocrinology and Metabolism, Department of Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Hayes MG; 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Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa., Shu XO; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Park KS; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, South Korea., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Netherlands Heart Institute, Utrecht, The Netherlands., Cruz M; Unidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rich SS; 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MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Lee J; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea., Kim BJ; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Stefansson K; deCODE Genetics, Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Ahlqvist E; Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden., Goodarzi MO; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Computational Medicine, Berlin Institute of Health at Charité-Universitätsmedizin, Berlin, Germany.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK., Haiman CA; Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Florez JC; 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All of Us Research Program, National Institutes of Health, Bethesda, MD, USA., Yamauchi T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan., Kadowaki T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.; Toranomon Hospital, Tokyo, Japan., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London NorthWest Healthcare NHS Trust, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Ng MCY; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Below JE; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Tsao PS; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; VA Palo Alto Health Care System, Palo Alto, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Chang KM; Corporal Michael J. 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Publikováno v:
Nature [Nature] 2024 Mar; Vol. 627 (8003), pp. 347-357. Date of Electronic Publication: 2024 Feb 19.
Autor:
Verma SS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gudiseva HV; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Chavali VRM; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salowe RJ; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bradford Y; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Guare L; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lucas A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Collins DW; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Vrathasha V; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Nair RM; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Rathi S; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhao B; Department of Statistics and Data Science, The Wharton School, University of Pennsylvania, Philadelphia, PA, USA., He J; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lee R; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zenebe-Gete S; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bowman AS; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., McHugh CP; New York Genome Center, New York, NY, USA., Zody MC; New York Genome Center, New York, NY, USA., Pistilli M; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Khachatryan N; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Daniel E; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Murphy W; Windell Murphy, MD, Philadelphia, PA, USA., Henderer J; Department of Ophthalmology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Kinzy TG; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA., Iyengar SK; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA., Peachey NS; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA; Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA., Taylor KD; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Guo X; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chen YI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Zangwill L; Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, La Jolla, CA, USA., Girkin C; Department of Ophthalmology and Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Ayyagari R; Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, La Jolla, CA, USA., Liebmann J; Department of Ophthalmology, Columbia University Medical Center, Columbia University, New York, NY, USA., Chuka-Okosa CM; Department of Ophthalmology, University of Nigeria, Ituku, Nigeria., Williams SE; Division of Ophthalmology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa., Akafo S; Unit of Ophthalmology, Department of Surgery, University of Ghana Medical School, Accra, Ghana., Budenz DL; Department of Ophthalmology, University of North Carolina, Chapel Hill, NC, USA., Olawoye OO; Department of Ophthalmology, University of Ibadan, Ibadan, Nigeria., Ramsay M; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Ashaye A; Department of Ophthalmology, University of Ibadan, Ibadan, Nigeria., Akpa OM; Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria., Aung T; Singapore Eye Research Institute, Singapore, Singapore., Wiggs JL; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA., Ross AG; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cui QN; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Addis V; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lehman A; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Miller-Ellis E; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sankar PS; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Williams SM; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Ying GS; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cooke Bailey J; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA; Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA; Department of Pharmacology and Toxicology, Center for Health Disparities, Brody School of Medicine. East Carolina University, Greenville, NC, 27834, USA., Rotter JI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Weinreb R; Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, La Jolla, CA, USA., Khor CC; Genome Institute of Singapore, Singapore, Singapore., Hauser MA; Department of Medicine, Duke University, Durham, NC, USA., Ritchie MD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., O'Brien JM; Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: joan.o'brien@pennmedicine.upenn.edu.
Publikováno v:
Cell [Cell] 2024 Jan 18; Vol. 187 (2), pp. 464-480.e10.
Autor:
Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de., Horn K; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Pott J; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Wuttke M; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.; Department of Medicine IV - Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany., Kühnapfel A; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Nasr MK; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Li Y; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Hoppmann A; Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ghasemi S; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Li M; Division of Nephrology and Hypertension, Department of Medicine, University of Utah, Salt Lake City, UT, USA., Tin A; Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, USA.; Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Cocca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wang J; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Nutile T; Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Department of Ocular Pathology and Imaging Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Åsvold BO; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Bansal N; Division of Nephrology, University of Washington, Seattle, WA, USA.; Kidney Research Institute, University of Washington, Seattle, WA, USA., Biggs ML; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Boutin T; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, Heidelberg University, Heidelberg, Germany., Brumpton B; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Burkhardt R; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Cai J; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Campbell H; Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Chalmers J; The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Cifkova R; Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer University Hospital, Prague, Czech Republic.; Department of Medicine II, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic., Daviglus M; Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA., Delgado G; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Dittrich K; University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany., Edwards TL; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Endlich K; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany., Michael Gaziano J; Massachusetts Veterans Epidemiology Research and Information Center, VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA., Giri A; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA.; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Gudbjartsson DF; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Iceland School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Hallan S; Department of Clinical and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Nephrology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Hamet P; Montreal University Hospital Research Center, CHUM, Montréal, QC, Canada.; Medpharmgene, Montreal, QC, Canada., Hartman CA; Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Hellwege JN; Department of Veteran's Affairs, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Holleczek B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Holm H; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Hutri-Kähönen N; Tampere Centre for Skills Training and Simulation, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Hveem K; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health, Norwegian University of Science and Technology, Trondheim, Norway., Isermann B; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute for Laboratory Medicine, University of Leipzig, Leipzig, Germany., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany.; Beijing Institute of Ophthalmology, Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland.; Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany., Joshi PK; Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Kanai M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Kastarinen M; Finnish Medicines Agency, Kuopio, Finland., Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Kiess W; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany., Körner A; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany.; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Kovacs P; Department of Medicine, University of Leipzig, Leipzig, Germany., Krajcoviechova A; Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer University Hospital, Prague, Czech Republic., Kramer H; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.; Division of Nephrology and Hypertension, Loyola University Chicago, Chicago, IL, USA., Krämer BK; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Kuokkanen M; Finnish Institute for Health and Welfare, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA., Lash JP; Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and The Wellbeing Services County of Pirkanmaa, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Li H; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Lin BM; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Liu J; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, and The Wellbeing Services County of Pirkanmaa, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Matsuda K; Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, the Netherlands., Mishra PP; Department of Clinical Chemistry, Fimlab Laboratories, and The Wellbeing Services County of Pirkanmaa, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, and The Wellbeing Services County of Pirkanmaa, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Montgomery GW; University of Queensland, Brisbane, QLD, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mychaleckyj JC; Center for Public Health Genomics, University of Virginia, Charlottesville, Charlottesville, VA, USA., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University Graz, Graz, Austria.; Synlab Academy, Synlab Holding Deutschland GmbH, Augsburg, Germany., Nauck M; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland.; Department of Cardiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Okada Y; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Department of Genome Informatics, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan., Olafsson I; Department of Clinical Biochemistry, Landspitali University Hospital, Reykjavik, Iceland., Oldehinkel AJ; Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, the Netherlands., Perola M; Finnish Institute for Health and Welfare, Helsinki, Finland.; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Pirastu N; Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.; Biostatistics Unit - Population and Medical Genomics Programme, Genomics Research Centre, Human Technopole Palazzo Italia, Viale Rita Levi‑Montalcini, 1, 20157, Milan, Italy., Polasek O; University of Split Medical School, Split, Croatia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Poulain T; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, Department of Epidemiology, Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Rabelink TJ; Department of Internal Medicine, Section of Nephrology, Leiden University Medical Center, Leiden, the Netherlands.; Einthoven Laboratory of Experimental Vascular Research, Leiden University Medical Center, Leiden, the Netherlands., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed H; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health, Norwegian University of Science and Technology, Trondheim, Norway.; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Division of Medicine and Laboratory Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway., Reilly DF; Janssen Pharmaceuticals Inc., Titusville, NJ, 08560, USA., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Richmond A; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Salomaa V; Finnish Institute for Health and Welfare, Helsinki, Finland., Schneiderman N; Department of Psychology, University of Miami, Coral Gables, FL, USA., Schöttker B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, Heidelberg University, Heidelberg, Germany., Sims M; Department of Social Medicine, Population and Public Health, University of California at Riverside School of Medicine, Riverside, CA, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Stark KJ; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Stocker H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Network Aging Research, Heidelberg University, Heidelberg, Germany., Stumvoll M; Department of Medicine, University of Leipzig, Leipzig, Germany., Sulem P; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Sveinbjornsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Svensson PO; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department of Cardiology, Södersjukhuset, Stockholm, Sweden., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Tayo BO; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA., Teren A; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Cardiology and Intensive Care Medicine, University Hospital OWL of Bielefeld University, Campus Klinikum Bielefeld, Teutoburger Straße 50, 33604, Bielefeld, Germany., Tham YC; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Thiery J; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute for Laboratory Medicine, University of Leipzig, Leipzig, Germany., Thio CHL; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Thomas LF; K. G. 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Publikováno v:
Nature communications [Nat Commun] 2024 Jan 18; Vol. 15 (1), pp. 586. Date of Electronic Publication: 2024 Jan 18.
Autor:
Li X; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Owen LA; Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA. Leah.owen@hsc.utah.edu.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA. Leah.owen@hsc.utah.edu.; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA. Leah.owen@hsc.utah.edu.; Department of Ophthalmology, University at Buffalo the State University of New York, Buffalo, NY, USA. Leah.owen@hsc.utah.edu., Taylor KD; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Ostmo S; Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA., Chen YI; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Coyner AS; Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA., Sonmez K; Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA., Hartnett ME; Byers Eye Institute at Stanford University, Palo Alto, CA, USA., Guo X; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Ipp E; Division of Endocrinology and Metabolism, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Roll K; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Genter P; Division of Endocrinology and Metabolism, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chan RVP; Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA., DeAngelis MM; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.; Department of Ophthalmology, University at Buffalo the State University of New York, Buffalo, NY, USA.; Department of Biochemistry; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo/State University of New York (SUNY), Buffalo, NY, USA.; Department of Neuroscience; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo/State University of New York (SUNY), Buffalo, NY, USA.; Department of Genetics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo/State University of New York (SUNY), Buffalo, NY, USA., Chiang MF; National Eye Institute, National Institutes of Health, Bethesda, MD, USA.; National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Campbell JP; Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA. campbelp@ohsu.edu., Rotter JI; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA. jrotter@lundquist.org.
Publikováno v:
Communications biology [Commun Biol] 2024 Jan 17; Vol. 7 (1), pp. 107. Date of Electronic Publication: 2024 Jan 17.