Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Buxbaum, Joseph D."'
Autor:
Tsetsos F; Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece., Topaloudi A; Department of Biological Sciences, Purdue University, West Lafayette, Indiana., Jain P; Department of Biological Sciences, Purdue University, West Lafayette, Indiana., Yang Z; Department of Biological Sciences, Purdue University, West Lafayette, Indiana., Yu D; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Kolovos P; Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece., Tumer Z; Department of Clinical Genetics, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rizzo R; Child and Adolescent Neurology and Psychiatry, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Hartmann A; Department of Neurology, Hôpital de la Pitié-Salpêtrière, Paris, France., Depienne C; Institute for Human Genetics, University Hospital Essen, Essen, Germany., Worbe Y; Assistance Publique Hôpitaux de Paris, Hôpital Saint-Antoine, Paris, France; French Reference Centre for Gilles de la Tourette Syndrome, Sorbonne University, Faculty of Medicine, Groupe Hospitalier Pitié-Salpêtrière, Paris, France., Müller-Vahl KR; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany., Cath DC; Department of Clinical and Health Psychology, Utrecht University, Utrecht, Netherlands., Boomsma DI; Institute for Anatomy and Cell Biology, Ulm University, Ulm, Germany; EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, the Netherlands., Wolanczyk T; Department of Child Psychiatry, Medical University of Warsaw, Warsaw, Poland., Zekanowski C; Department of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland., Barta C; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis Egyetem, Budapest, Hungary., Nemoda Z; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis Egyetem, Budapest, Hungary., Tarnok Z; Vadaskert Clinic for Child and Adolescent Psychiatry, Budapest, Hungary., Padmanabhuni SS; Department of Biological Sciences, Purdue University, West Lafayette, Indiana., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Grice D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Tics, OCD, and Related Disorders, Icahn School of Medicine at Mount Sinai, New York, New York., Glennon J; Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., Stefansson H; deCODE Genetics, Amgen, Iceland., Hengerer B; Boehringer Ingelheim Pharma GmbH & Co. KG, CNS Research, Biberach, Germany., Yannaki E; Hematology Department, Hematopoietic Cell Transplantation Unit, Gene and Cell Therapy Center, George Papanikolaou Hospital, Thessaloniki, Greece; Department of Medicine, University of Washington, Seattle, Washington., Stamatoyannopoulos JA; Altius Institute for Biomedical Sciences, Seattle, Washington; Department of Genome Sciences, University of Washington, Seattle, Washington; Department of Medicine, Division of Oncology, University of Washington, Seattle, Washington., Benaroya-Milshtein N; Child and Adolescent Psychiatry Department, Schneider Children's Medical Center of Israel, Petah-Tikva. Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Cardona F; Department of Human Neurosciences, University La Sapienza of Rome, Rome, Italy., Hedderly T; Evelina London Children's Hospital GSTT, Kings Health Partners AHSC, London, UK., Heyman I; Psychological Medicine, Great Ormond Street Hospital NHS Foundation Trust, London, UK., Huyser C; Levvel Academic Center for Child and Adolescent Psychiatry, Amsterdam, the Netherlands; Amsterdam UMC, Department of Child and Adolescent Psychiatry, Amsterdam, the Netherlands., Mir P; Unidad de Trastornos del Movimiento, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Morer A; Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic Universitari, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain; Centro de Investigacion en Red de Salud Mental, Instituto Carlos III, Madrid, Spain., Mueller N; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany., Munchau A; Institute of Systems Motor Science, University of Lübeck, Lübeck, Germany., Plessen KJ; Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region of Denmark and University of Copenhagen, Copenhagen, Denmark; Division of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland., Porcelli C; ASL BA, Maternal and Childood Department, Adolescence and Childhood Neuropsychiatry Unit, Bari, Italy., Roessner V; Department of Child and Adolescent Psychiatry, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany., Walitza S; Department of Child and Adolescent Psychiatry and Psychotherapy, University of Zürich, Zurich, Switzerland., Schrag A; Department of Clinical Neuroscience, UCL Institute of Neurology, University College London, London, UK., Martino D; Department of Clinical Neurosciences, Cumming School of Medicine & Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada., Tischfield JA; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway, New Jersey., Heiman GA; Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway, New Jersey., Willsey AJ; Department of Psychiatry and Behavioral Sciences, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, California., Dietrich A; University of Groningen, University Medical Center Groningen, Department of Child and Adolescent Psychiatry, Groningen, the Netherlands., Davis LK; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center Nashville, Nashville, Tennessee; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee., Crowley JJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Mathews CA; Department of Psychiatry and Genetics Institute, University of Florida College of Medicine, Gainesville, Florida., Scharf JM; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts., Georgitsi M; 1st Laboratory of Medical Biology-Genetics, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece., Hoekstra PJ; University of Groningen, University Medical Center Groningen, Department of Child and Adolescent Psychiatry, Groningen, the Netherlands. Electronic address: p.hoekstra@accare.nl., Paschou P; Department of Biological Sciences, Purdue University, West Lafayette, Indiana. Electronic address: ppaschou@purdue.edu.
Publikováno v:
Biological psychiatry [Biol Psychiatry] 2024 Jul 15; Vol. 96 (2), pp. 114-124. Date of Electronic Publication: 2023 Feb 02.
Autor:
Trubetskoy V; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Pardiñas AF; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Qi T; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; School of Life Sciences, Westlake University, Hangzhou, China., Panagiotaropoulou G; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Awasthi S; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Bigdeli TB; Department of Psychiatry and the Behavioral Sciences, SUNY Downstate Medical Center, New York, NY, USA.; Institute for Genomic Health, SUNY Downstate Medical Center, New York, NY, USA.; Department of Psychiatry, Veterans Affairs New York Harbor Healthcare System, New York, NY, USA., Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Chen CY; Biogen, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Dennison CA; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Hall LS; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Lam M; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Research Division, Institute of Mental Health, Singapore, Republic of Singapore.; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA., Watanabe K; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Frei O; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway., Ge T; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Harwood JC; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Koopmans F; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Faculty of Science, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands., Magnusson S; deCODE Genetics, Amgen, Reykjavik, Iceland., Richards AL; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Sidorenko J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Wu Y; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Zeng J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Grove J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Kim M; Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Li Z; Affiliated Hospital of Qingdao University and Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, China.; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China., Voloudakis G; Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics, Friedman Brain Institute, Department of Genetics and Genomic Science and Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zhang W; Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics, Friedman Brain Institute, Department of Genetics and Genomic Science and Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Adams M; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK., Agartz I; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden., Atkinson EG; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Agerbo E; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark., Al Eissa M; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Albus M; Comedicum Lindwurmhof, Munich, Germany., Alexander M; Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA., Alizadeh BZ; University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, University of Groningen, Groningen, The Netherlands.; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Alptekin K; Department of Psychiatry, Dokuz Eylül University School of Medicine, Izmir, Turkey.; Department of Neuroscience, Dokuz Eylül University Graduate School of Health Sciences, Izmir, Turkey., Als TD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Amin F; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA., Arolt V; Department of Psychiatry, University of Münster, Münster, Germany., Arrojo M; Servizo de Psiquiatría, Complexo Hospitalario Universitario de Santiago de Compostela, Servizo Galego de Saúde (SERGAS), Santiago de Compostela, Spain., Athanasiu L; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Azevedo MH; Institute of Medical Psychology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Bacanu SA; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Bass NJ; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Begemann M; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Belliveau RA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bene J; Department of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary., Benyamin B; Australian Centre for Precision Health, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, South Australia, Australia.; UniSA Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Bergen SE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Blasi G; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Bobes J; Área de Psiquiatría-Universidad de Oviedo, Hospital Universitario Central de Asturias (HUCA), Asturias, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, Oviedo, Asturias, Spain., Bonassi S; Unit of Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma and San Raffaele University, Rome, Italy., Braun A; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Bressan RA; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil., Bromet EJ; Department of Psychiatry and Behavioural Health, Stony Brook University, Stony Brook, NY, USA., Bruggeman R; University Medical Center Groningen, University Center for Psychiatry, Rob Giel Research Center, University of Groningen, Groningen, The Netherlands.; Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands., Buckley PF; Health Science Center, University of Tennessee, Memphis, TN, USA., Buckner RL; Department of Psychology, Harvard University, Cambridge, MA, USA., Bybjerg-Grauholm J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Cahn W; University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.; Altrecht, General Menthal Health Care, Utrecht, The Netherlands., Cairns MJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, New South Wales, Australia., Calkins ME; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Carr VJ; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Department of Psychiatry, Monash University, Melbourne, Victoria, Australia.; Neuroscience Research Australia, Sydney, New South Wales, Australia., Castle D; Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia.; St Vincent's Hospital, Melbourne, Victoria, Australia., Catts SV; Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.; School of Medicine, University of Queensland, Herston, Queensland, Australia., Chambert KD; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chan RCK; Institute of Psychology, Chinese Academy of Science, Beijing, China.; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China., Chaumette B; INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France.; Department of Psychiatry, McGill University, Montreal, Québec, Canada., Cheng W; Department of Computer Science, University of North Carolina, Chapel Hill, NC, USA., Cheung EFC; Castle Peak Hospital, Hong Kong, China., Chong SA; Research Division, Institute of Mental Health, Singapore, Republic of Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore., Cohen D; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Institut des Systèmes Intelligents et de Robotique (ISIR), CNRS UMR7222, Faculté des Sciences et Ingénierie, Sorbonne Université, Paris, France., Consoli A; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Cordeiro Q; Department of Psychiatry, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil., Costas J; Instituto de Investigación Sanitaria (IDIS) de Santiago de Compostela, Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), Servizo Galego de Saúde (SERGAS), Santiago de Compostela, Spain., Curtis C; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Davidson M; University of Nicosia Medical School, Nicosia, Cyprus., Davis KL; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., de Haan L; Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.; Arkin, Institute for Mental Health, Amsterdam, The Netherlands., Degenhardt F; Institute of Human Genetics, University of Bonn, Bonn, Germany., DeLisi LE; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Cambridge Health Alliance, Cambridge, MA, USA., Demontis D; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Dickerson F; Sheppard Pratt Health System, Baltimore, MD, USA., Dikeos D; First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece., Dinan T; Department of Psychiatry and Neurobehavioural Sciences, University College Cork, Cork, Ireland.; APC Microbiome Ireland, University College Cork, Cork, Ireland., Djurovic S; NORMENT Centre, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Duan J; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL, USA.; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL, USA., Ducci G; Department of Mental Health, ASL Rome 1, Rome, Italy., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, UK., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.; Department of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore., Fañanás L; Department of Evolutionary Biology, Ecology and Environmental Sciences, Faculty of Biology, University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain., Faraone SV; Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA., Fiorentino A; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Forstner A; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Centre for Human Genetics, University of Marburg, Marburg, Germany., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Freimer NB; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA., Fromer M; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Frustaci A; Barnet, Enfield and Haringey Mental Health NHS Trust, St Ann's Hospital, London, UK., Gadelha A; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil., Genovese G; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gershon ES; Departments of Psychiatry and Human Genetics, University of Chicago, Chicago, IL, USA., Giannitelli M; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Giegling I; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Giusti-Rodríguez P; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Godard S; Departments of Psychiatry and Human and Molecular Genetics, INSERM, Institut de Myologie, Hôpital de la Pitiè-Salpêtrière, Paris, France., Goldstein JI; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., González Peñas J; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., González-Pinto A; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; BIOARABA Health Research Institute, OSI Araba, University Hospital, University of the Basque Country, Vitoria, Spain., Gopal S; Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA., Gratten J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia., Green MF; Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA., Greenwood TA; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Guillin O; INSERM, Rouen, France.; Centre Hospitalier du Rouvray, Rouen, France.; UFR Santé, Université de Rouen Normandie, Rouen, France., Gülöksüz S; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Gur RE; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Gur RC; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Gutiérrez B; Department of Psychiatry, Faculty of Medicine and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain., Hahn E; Department of Psychiatry, Charité - Universitätsmedizin, Berlin, Germany., Hakonarson H; Children's Hospital of Philadelphia, Leonard Madlyn Abramson Research Center, Philadelphia, PA, USA., Haroutunian V; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mental Illness Research Clinical and Education Center (MIRECC), JJ Peters VA Medical Center, New York, NY, USA., Hartmann AM; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Harvey C; Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia.; NorthWestern Mental Health, Melbourne, Victoria, Australia., Hayward C; MRC Human Genetics Unit, University of Edinburgh, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK., Henskens FA; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Herms S; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Hoffmann P; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Howrigan DP; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ikeda M; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake Aichi, Japan., Iyegbe C; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Joa I; Regional Centre for Clinical Research in Psychosis, Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway., Julià A; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Kähler AK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kam-Thong T; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland., Kamatani Y; Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Karachanak-Yankova S; Department of Medical Genetics, Medical University, Sofia, Bulgaria.; Department of Genetics, Faculty of Biology, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria., Kebir O; INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France., Keller MC; Institute for Behavioural Genetics, University of Colorado Boulder, Boulder, CO, USA., Kelly BJ; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Khrunin A; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', Moscow, Russia., Kim SW; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea., Klovins J; Latvian Biomedical Research and Study Centre, Riga, Latvia., Kondratiev N; Mental Health Research Center, Moscow, Russian Federation., Konte B; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Kraft J; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Berlin, Germany., Kubo M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kučinskas V; Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Kučinskiene ZA; Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Kusumawardhani A; Psychiatry Department, University of Indonesia - Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia., Kuzelova-Ptackova H; Department of Psychiatry, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic., Landi S; Dipartimento di Biologia, Universita' di Pisa, Pisa, Italy., Lazzeroni LC; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Lee PH; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Legge SE; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Lehrer DS; Department of Psychiatry, Wright State University, Dayton, OH, USA., Lencer R; Department of Psychiatry, University of Münster, Münster, Germany., Lerer B; Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Li M; Zhongshan School of Medicine and Key Laboratory of Tropical Diseases Control (SYSU), Sun Yat-sen University, Guangzhou, China., Lieberman J; Department of Psychiatry, Columbia University, New York, NY, USA., Light GA; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; VISN 22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, USA., Limborska S; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', Moscow, Russia., Liu CM; Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan., Lönnqvist J; Mental Health Unit, Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry, University of Helsinki, Helsinki, Finland., Loughland CM; Hunter New England Health and University of Newcastle, Newcastle, New South Wales, Australia., Lubinski J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University in Szczecin, Szczecin, Poland., Luykx JJ; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Psychiatry, UMC Utrecht Brain Center, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Second Opinion Outpatient Clinic, GGNet Mental Health, Warnsveld, The Netherlands., Lynham A; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Macek M Jr; Department of Biology and Medical Genetics, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic., Mackinnon A; Black Dog Institute, University of New South Wales, Randwick, New South Wales, Australia.; Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Maher BS; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Maier W; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Malaspina D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mallet J; Asfalia Biologics, iPEPS-ICM, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Marder SR; Semel Institute for Neurosciene, University of California Los Angeles, Los Angeles, CA, USA., Marsal S; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Martin AR; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Martorell L; Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain., Mattheisen M; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany., McCarley RW; VA Boston Health Care System, Brockton, MA, USA., McDonald C; Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland., McGrath JJ; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Brisbane, Queensland, Australia., Medeiros H; Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; College of Medicine, SUNY Downstate Health Sciences University, New York, NY, USA., Meier S; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Melegh B; Department of Medical Genetics, University of Pécs, School of Medicine, Pécs, Hungary., Melle I; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Mesholam-Gately RI; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA, USA., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Michie PT; School of Psychology, University of Newcastle, Newcastle, New South Wales, Australia., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Milanova V; Psychiatric Clinic, Alexandrovska University Hospital, Sofia, Bulgaria., Mitjans M; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Molden E; Department of Pharmacy, University of Oslo, Oslo, Norway.; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway., Molina E; Department of Nursing, Faculty of Health Sciences and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain., Molto MD; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Genetics, Faculty of Biological Sciences, Universidad de Valencia, Valencia, Spain.; Biomedical Research Institute INCLIVA, Valencia, Spain., Mondelli V; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Moreno C; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., Morley CP; Departments of Public Health and Preventive Medicine, Family Medicine, and Psychiatry and Behavioral Sciences, State University of New York, Upstate Medical University, Syracuse, NY, USA., Muntané G; Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.; Institut de Biologia Evolutiva (UPF-CSIC), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Spain., Murphy KC; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland., Myin-Germeys I; Department for Neurosciences, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium., Nenadić I; Cognitive Neuropsychiatry Laboratory, Department of Psychiatry and Psychotherapy, Philipps Universität Marburg, Marburg, Germany.; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany., Nestadt G; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nikitina-Zake L; Latvian Biomedical Research and Study Centre, Riga, Latvia., Noto C; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil., Nuechterlein KH; Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., O'Brien NL; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., O'Neill FA; Centre for Public Health, Institute of Clinical Sciences, Queen's University Belfast, Belfast, UK., Oh SY; Department of Statistics and Applied Probability, University of California at Santa Barbara, Santa Barbara, CA, USA.; Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Olincy A; Department of Psychiatry, University of Colorado Denver, Aurora, CO, USA., Ota VK; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil., Pantelis C; NorthWestern Mental Health, Melbourne, Victoria, Australia.; Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia.; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia., Papadimitriou GN; First Department of Psychiatry, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, Athens, Greece., Parellada M; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., Paunio T; Department of Public Health Solutions, Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry and SleepWell Research Program, Faculty of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Pellegrino R; Children's Hospital of Philadelphia, Leonard Madlyn Abramson Research Center, Philadelphia, PA, USA., Periyasamy S; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia., Perkins DO; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA., Pfuhlmann B; Clinic of Psychiatry and Psychotherapy, Weißer Hirsch, Dresden, Germany., Pietiläinen O; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Pimm J; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Porteous D; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Powell J; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Quattrone D; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; South London and Maudsley NHS Mental Health Foundation Trust, London, UK., Quested D; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.; Department of Psychiatry, University of Oxford, Oxford, UK., Radant AD; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System, Seattle, WA, USA., Rampino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Rapaport MH; Huntsman Mental Health Institute, Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA., Rautanen A; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland., Reichenberg A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Roe C; SUNY Upstate Medical University, Syracuse, NY, USA., Roffman JL; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Roth J; Department of Psychiatry, Psychosomatics and Psychotherapy, Julius-Maximilians-Universität Würzburg, Würzburg, Germany., Rothermundt M; Department of Psychiatry, University of Münster, Münster, Germany., Rutten BPF; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands., Saker-Delye S; Généthon, Evry, France., Salomaa V; THL-Finnish Institute for Health and Welfare, Helsinki, Finland., Sanjuan J; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Biomedical Research Institute INCLIVA, Valencia, Spain.; Department of Psychiatry, School of Medicine, University of Valencia, Hospital Clínico Universitario de Valencia, Valencia, Spain., Santoro ML; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil., Savitz A; Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA., Schall U; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Priority Centre for Brain and Mental Health Research, University of Newcastle, Mater Hospital, McAuley Centre, Newcastle, New South Wales, Australia., Scott RJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Division of Molecular Medicine, NSW Health Pathology North, Newcastle, New South Wales, Australia., Seidman LJ; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA, USA., Sharp SI; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Siever LJ; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; James J. Peters VA Medical Center, Bronx, NY, USA., Sigurdsson E; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Psychiatry, Landspitali University Hospital, Reykjavik, Iceland., Sim K; West Region, Institute of Mental Health, Singapore, Singapore.; Yoo Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Skarabis N; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Slominsky P; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', Moscow, Russia., So HC; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China., Sobell JL; Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Söderman E; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden., Stain HJ; School of Social and Health Sciences, Leeds Trinity University, Leeds, UK.; TIPS - Network for Clinical Research in Psychosis, Stavanger University Hospital, Stavanger, Norway., Steen NE; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Steixner-Kumar AA; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Stögmann E; Department of Neurology, Medical University of Vienna, Vienna, Austria., Stone WS; Harvard Medical School Department of Psychiatry at Beth Israel Deaconess Medical Center, Boston, MA, USA.; Massachusetts Mental Health Center, Boston, MA, USA., Straub RE; Lieber Institute for Brain Development, Baltimore, MD, USA., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Strengman E; Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands., Stroup TS; Department of Psychiatry, Columbia University, New York, NY, USA., Subramaniam M; Research Division, Institute of Mental Health, Singapore, Republic of Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore., Sugar CA; Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA., Suvisaari J; THL-Finnish Institute for Health and Welfare, Helsinki, Finland., Svrakic DM; Department of Psychiatry, Washington University, St Louis, MO, USA., Swerdlow NR; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA., Szatkiewicz JP; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Ta TMT; Department of Psychiatry, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany., Takahashi A; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Thibaut F; Université de Paris, Faculté de Médecine, Hôpital Cochin-Tarnier, Paris, France.; INSERM U1266, Institut de Psychiatrie et de Neurosciences, Paris, France., Toncheva D; Department of Medical Genetics, Medical University, Sofia, Bulgaria.; Bulgarian Academy of Science, Sofia, Bulgaria., Tooney PA; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, New South Wales, Australia., Torretta S; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Tosato S; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy., Tura GB; Psychiatry Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Turetsky BI; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Üçok A; Department of Psychiatry, Faculty of Medicine, Istanbul University, Istanbul, Turkey., Vaaler A; Division of Mental Health, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway., van Amelsvoort T; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands., van Winkel R; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Neurosciences, Center for Clinical Psychiatry, KU Leuven, Leuven, Belgium., Veijola J; Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland.; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Waddington J; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Walter H; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany., Waterreus A; Neuropsychiatric Epidemiology Research Unit, School of Population and Global Health, University of Western Australia, Perth, Western Australia, Australia.; Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Western Australia, Australia., Webb BT; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Weiser M; Sheba Medical Center, Tel Hashomer, Israel., Williams NM; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Wormley BK; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Wu JQ; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Xu Z; Department of Psychiatry, GGz Centraal, Utrecht, The Netherlands., Yolken R; Stanley Neurovirology Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zai CC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Zhou W; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China., Zhu F; Department of Psychiatry, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Zimprich F; Department of Neurology, Medical University of Vienna, Vienna, Austria., Atbaşoğlu EC; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Psychiatry, School of Medicine, Ankara University, Ankara, Turkey., Ayub M; Department of Psychiatry, Queens University Kingston, Kingston, Ontario, Canada., Benner C; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Bertolino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy., Black DW; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Bray NJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Breen G; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Buccola NG; School of Nursing, Louisiana State University Health Sciences Center, New Orleans, LA, USA., Byerley WF; Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA., Chen WJ; Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan Town, Taiwan.; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan., Cloninger CR; Department of Psychiatry, Washington University, St Louis, MO, USA., Crespo-Facorro B; University of Sevilla, CIBERSAM IBiS, Seville, Spain.; Hospital Universitario Virgen del Rocio, Department of Psychiatry, Universidad del Sevilla, Seville, Spain., Donohoe G; Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland., Freedman R; Department of Psychiatry, University of Colorado Denver, Aurora, CO, USA., Galletly C; Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia.; Ramsay Health Care (SA) Mental Health, Adelaide, South Australia, Australia.; Northern Adelaide Local Health Network, Adelaide, South Australia, Australia., Gandal MJ; Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Gennarelli M; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Genetic Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Hougaard DM; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Hwu HG; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei, Taiwan.; Department of Psychiatry, College of Medicine and National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan., Jablensky AV; Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Western Australia, Australia., McCarroll SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Moran JL; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Mors O; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Psychosis Research Unit, Aarhus University Hospital, Aarhus, Denmark., Mortensen PB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark., Müller-Myhsok B; Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.; Department of Health Data Science, University of Liverpool, Liverpool, UK., Neil AL; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Nordentoft M; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark., Pato MT; Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.; Rutgers University, New Jersey Medical School, Newark, NJ, USA., Petryshen TL; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Pirinen M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Pulver AE; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Schulze TG; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, MD, USA., Silverman JM; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; James J. Peters VA Medical Center, Bronx, NY, USA., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Stahl EA; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Regeneron Genetics Center, Orange, CA, USA., Tsuang DW; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System, Seattle, WA, USA., Vilella E; Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain., Wang SH; College of Public Health, China Medical University, Taichung, Taiwan., Xu S; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, School of Life Sciences, Fudan University, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China., Adolfsson R; Department of Clinical Sciences, Psychiatry, Umeå University, Umeå, Sweden., Arango C; Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Madrid, Spain.; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain., Baune BT; Department of Psychiatry, University of Münster, Münster, Germany.; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia., Belangero SI; Laboratory of Integrative Neuroscience, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Morphology and Genetics, Laboratorio de Genetica, Universidade Federal de São Paulo, São Paulo, Brazil., Børglum AD; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Braff D; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; VISN 22, Mental Illness Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, USA., Bramon E; Division of Psychiatry, Department of Mental Health Neuroscience, University College London, London, UK., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Campion D; INSERM, Rouen, France.; Centre Hospitalier du Rouvray, Rouen, France., Cervilla JA; Department of Psychiatry, San Cecilio University Hospital, University of Granada, Granada, Spain., Cichon S; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany., Collier DA; Eli Lilly and Company, Windlesham, UK., Corvin A; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Curtis D; UCL Genetics Institute, University College London, London, UK.; Centre for Psychiatry, Queen Mary University London, London, UK., Forti MD; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; South London and Maudsley NHS Mental Health Foundation Trust, London, UK., Domenici E; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy., Ehrenreich H; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Escott-Price V; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.; Dementia Research Institute, Cardiff University, Cardiff, UK., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Fanous AH; Department of Psychiatry, Veterans Affairs New York Harbor Healthcare System, New York, NY, USA.; Department of Psychiatry, Phoenix VA Healthcare System, Phoenix, AZ, USA.; Banner-University Medical Center, Phoenix, AZ, USA., Gareeva A; Department of Human Molecular Genetics of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences (IBG UFRC RAS), Ufa, Russia.; Federal State Educational Institution of Highest Education Bashkir State Medical University of Public Health Ministry of Russian Federation (BSMU), Ufa, Russia., Gawlik M; 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Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Iwata N; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake Aichi, Japan., Jönsson EG; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Kahn RS; University Medical Center Utrecht, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kennedy JL; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Khusnutdinova E; Department of Human Molecular Genetics of the Institute of Biochemistry and Genetics of the Ufa Federal Research Center of the Russian Academy of Sciences (IBG UFRC RAS), Ufa, Russia.; Federal State Educational Institution of Highest Education Bashkir State Medical University of Public Health Ministry of Russian Federation (BSMU), Ufa, Russia., Kirov G; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Knowles JA; Department of Psychiatry and Zilkha Neurogenetics Institute, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.; Department of Cell Biology, State University of New York, Downstate Health Sciences University, New York, NY, USA., Krebs MO; INSERM U1266, Institute of Psychiatry and Neuroscience of Paris, Université de Paris, GHU Paris Psychiatrie & Neurosciences, Paris, France., Laurent-Levinson C; Faculté de Médecine Sorbonne Université, Groupe de Recherche Clinique no. 15 - Troubles Psychiatriques et Développement (PSYDEV), Department of Child and Adolescent Psychiatry, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France.; Centre de Référence des Maladies Rares à Expression Psychiatrique, Department of Child and Adolescent Psychiatry, AP-HP Sorbonne Université, Hôpital Universitaire de la Pitié-Salpêtrière, Paris, France., Lee J; Department of Psychosis, Institute of Mental Health, Singapore, Singapore.; Neuroscience and Mental Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Lencz T; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Institute of Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA.; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA., Levinson DF; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Li QS; Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA., Liu J; Human Genetics, Genome Institute of Singapore, A*STAR, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Malhotra AK; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Institute of Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA.; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA., Malhotra D; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffman-La Roche, Basel, Switzerland., McIntosh A; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK., McQuillin A; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Menezes PR; Department of Preventative Medicine, Faculdade de Medicina FMUSP, University of São Paulo, São Paulo, Brazil., Morgan VA; Neuropsychiatric Epidemiology Research Unit, School of Population and Global Health, University of Western Australia, Perth, Western Australia, Australia.; Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Western Australia, Australia., Morris DW; Centre for Neuroimaging, Cognition and Genomics (NICOG), National University of Ireland Galway, Galway, Ireland., Mowry BJ; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia., Murray RM; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Nimgaonkar V; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany., Ophoff RA; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, Erasmus University Medical Center, Rotterdam, The Netherlands., Paciga SA; Early Clinical Development, Pfizer Worldwide Research and Development, Groton, CT, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pato CN; Rutgers University, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.; Rutgers University, New Jersey Medical School, Newark, NJ, USA., Qin S; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China.; Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Riley BP; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Rivera M; Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.; Institute of Neurosciences, Biomedical Research Center (CIBM), University of Granada, Granada, Spain., Rujescu D; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Saka MC; Department of Psychiatry, School of Medicine, Ankara University, Ankara, Turkey., Sanders AR; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL, USA.; Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL, USA., Schwab SG; Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.; Illawarra Health and Medical Research Institute, Wollongong, New South Wales, Australia., Serretti A; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Sham PC; Centre for PanorOmic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Brain and Cognitive Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Department of Psychiatry, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Shi Y; Affiliated Hospital of Qingdao University and Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes), Qingdao University, Qingdao, China.; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Collaborative Innovation Center for Brain Science, Shanghai Jiao Tong University, Shanghai, China., St Clair D; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Stefánsson H; deCODE Genetics, Amgen, Reykjavik, Iceland., Stefansson K; deCODE Genetics, Amgen, Reykjavik, Iceland., Tsuang MT; Center for Behavioral Genomics, Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Institute of Genomic Medicine, University of California San Diego, La Jolla, CA, USA., van Os J; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; University Medical Center Utrecht, Department of Psychiatry, Utrecht, The Netherlands., Vawter MP; Department of Psychiatry and Human Behavior, School of Medicine, University of California Irvine, Irvine, CA, USA., Weinberger DR; Lieber Institute for Brain Development, Baltimore, MD, USA., Werge T; Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Center for GeoGenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Copenhagen, Denmark., Wildenauer DB; School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia., Yu X; Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing, China.; National Clinical Research Center for Mental Disorders, NHC Key Laboratory of Mental Health (Peking University) and Chinese Academy of Medical Sciences Research Unit, Beijing, China., Yue W; Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing, China.; National Clinical Research Center for Mental Disorders, NHC Key Laboratory of Mental Health (Peking University) and Chinese Academy of Medical Sciences Research Unit, Beijing, China.; PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, China., Holmans PA; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Pocklington AJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Roussos P; Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics, Friedman Brain Institute, Department of Genetics and Genomic Science and Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mental Illness Research, Education, and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, New York, NY, USA., Vassos E; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Oxford Health NHS Foundation Trust, Oxford, UK., Verhage M; Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research, University Medical Center Amsterdam, Amsterdam, The Netherlands.; Department of Functional Genomics, Faculty of Exact Science, Center for Neurogenomics and Cognitive Research, VU University Amsterdam and VU Medical Center, Amsterdam, The Netherlands., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Yang J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China., Posthuma D; Department of Functional Genomics, Faculty of Exact Science, Center for Neurogenomics and Cognitive Research, VU University Amsterdam and VU Medical Center, Amsterdam, The Netherlands., Andreassen OA; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Kendler KS; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Wray NR; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Daly MJ; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Huang H; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Neale BM; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA., Ripke S; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany. sripke@broadinstitute.org.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. sripke@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. sripke@broadinstitute.org., Walters JTR; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK. 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Publikováno v:
Nature [Nature] 2022 Apr; Vol. 604 (7906), pp. 502-508. Date of Electronic Publication: 2022 Apr 08.
Autor:
Mahjani B; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Klei L; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Mattheisen M; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Halvorsen MW; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Reichenberg A; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Roeder K; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Pedersen NL; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Boberg J; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., de Schipper E; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Bulik CM; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Landén M; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Fundín B; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Mataix-Cols D; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Sandin S; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Hultman CM; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Crowley JJ; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Buxbaum JD; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Rück C; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Devlin B; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück)., Grice DE; Seaver Autism Center for Research and Treatment (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Division of Tics, Obsessive-Compulsive Disorder (OCD), and Related Disorders (Mahjani, Grice), Department of Psychiatry (Mahjani, Reichenberg, Sandin, Buxbaum, Grice),Mindich Child Health and Development Institute (Reichenberg, Buxbaum, Grice),Department of Genetics and Genomic Sciences (Buxbaum),Department of Neuroscience (Buxbaum), and Friedman Brain Institute (Buxbaum, Grice), Icahn School of Medicine at Mount Sinai, New York; Department of Medical Epidemiology and Biostatistics (Mahjani, Mattheisen, Halvorsen, Pedersen, Bulik, Landén, Fundín, Sandin, Hultman, Crowley) and Center for Psychiatry Research, Department of Clinical Neuroscience (Boberg, de Schipper, Mataix-Cols, Rück), Karolinska Institutet, Stockholm; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh (Klei, Devlin); Department of Psychiatry and Department of Community Health and Epidemiology, Dalhousie University, Halifax, Canada (Mattheisen); Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark (Mattheisen); Institute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich (Mattheisen); Department of Genetics (Halvorsen, Crowley) Department of Psychiatry (Bulik), and Department of Nutrition (Bulik), University of North Carolina at Chapel Hill; Department of Statistics and the Computational Biology Department, Carnegie Mellon University, Pittsburgh (Roeder); Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (Landén); Health Care Services, Region Stockholm, Stockholm (Rück).
Publikováno v:
The American journal of psychiatry [Am J Psychiatry] 2022 Mar; Vol. 179 (3), pp. 216-225. Date of Electronic Publication: 2021 Nov 18.
Autor:
Betancur C; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine, Institut de Biologie Paris Seine, Paris 75005, France., Buxbaum JD; Seaver Autism Center for Research and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. Electronic address: joseph.buxbaum@mssm.edu.
Publikováno v:
Current opinion in genetics & development [Curr Opin Genet Dev] 2020 Dec; Vol. 65, pp. 69-75. Date of Electronic Publication: 2020 Jun 26.
Autor:
Nguyen HT; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. tan-hoang.nguyen@mssm.edu., Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kim A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Surgery, Massachusetts General Hospital, Boston, 02114, MA, USA., Dobbyn A; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Huckins LM; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Munoz-Manchado AB; Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, SE-17177, Sweden., Ruderfer DM; Division of Genetic Medicine, Departments of Medicine, Psychiatry and Biomedical Informatics, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, 37235, TN, USA., Genovese G; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Cambridge, Massachusetts, USA., Fromer M; Verily Life Sciences, 269 E Grand Ave, South San Francisco, 94080, CA, USA., Xu X; Seaver Autism Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Pinto D; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Seaver Autism Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Linnarsson S; Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, SE-17177, Sweden., Verhage M; Department of Functional Genomics, The Center for Neurogenomics and Cognitive Research, VU University and VU Medical Center, Amsterdam, The Netherlands., Smit AB; Department of Molecular and Cellular Neurobiology, The Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands., Hjerling-Leffler J; Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, SE-17177, Sweden., Buxbaum JD; Seaver Autism Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Hultman C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Sklar P; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Purcell SM; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; Sleep Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Lage K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Surgery, Massachusetts General Hospital, Boston, 02114, MA, USA., He X; Department of Human Genetics, University of Chicago, Chicago, 60637, IL, USA., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, 27599-7264, North Carolina, USA., Stahl EA; Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. eli.stahl@mssm.edu.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. eli.stahl@mssm.edu.
Publikováno v:
Genome medicine [Genome Med] 2017 Dec 20; Vol. 9 (1), pp. 114. Date of Electronic Publication: 2017 Dec 20.
Autor:
Jun GR; Neurogenetics and Integrated Genomics, Andover Innovative Medicines Institute, Eisai Inc, Andover, MA, USA; Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine, Boston, MA, USA., Chung J; Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine, Boston, MA, USA., Mez J; Department of Neurology, Boston University Schools of Medicine, Boston, MA, USA., Barber R; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA., Beecham GW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Bennett DA; Department of Neurological Sciences and Rush Alzheimer's Disease Center, Chicago, IL, USA., Buxbaum JD; Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA; Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA; Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY, USA., Byrd GS; Department of Biology, North Carolina A&T State University, Greensboro, NC, USA., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Crane PK; Department of Medicine, University of Washington, Seattle, WA, USA., Cruchaga C; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, MO, USA; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., De Jager P; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Evans D; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA., Fallin MD; Department of Mental Health, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Foroud TM; Department of Medical & Molecular Genetics, Indiana University, Indianapolis, IN, USA., Friedland RP; Department of Neurology, University of Louisville, Louisville, KY, USA., Goate AM; Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA., Graff-Radford NR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Hendrie H; Department of Psychiatry, Indiana University, Indianapolis, IN, USA; Regenstrief Institute, Inc, Indianapolis, IN, USA., Hall KS; Regenstrief Institute, Inc, Indianapolis, IN, USA; Department of Medicine, Indiana University, Indianapolis, IN, USA., Hamilton-Nelson KL; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Inzelberg R; Department of Neurology and Neurosurgery, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Kamboh MI; University of Pittsburgh Alzheimer's Disease Research Center and Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA., Kauwe JSK; Department of Biology, Brigham Young University, Provo, UT, USA., Kukull WA; Department of Epidemiology, University of Washington, Seattle, WA, USA; National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA., Kunkle BW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Kuwano R; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan., Larson EB; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA; Group Health, Group Health Research Institute, Seattle, WA, USA., Logue MW; Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine, Boston, MA, USA; Department of Neurological Sciences and Rush Alzheimer's Disease Center, Chicago, IL, USA; National Center for PTSD, Behavioral Science Division, Boston VA Healthcare System, Boston, MA, USA., Manly JJ; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Martin ER; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Montine TJ; Department of Pathology, Stanford University, Stanford, CA, USA., Mukherjee S; Department of Medicine, University of Washington, Seattle, WA, USA., Naj A; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Reiman EM; Arizona Alzheimer's Consortium, Phoenix, AZ, USA; Department of Psychiatry, University of Arizona, Phoenix, AZ, USA; Banner Alzheimer's Institute, Phoenix, AZ, USA; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA., Reitz C; The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA; The Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA; The Department of Epidemiology, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Sherva R; Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine, Boston, MA, USA., St George-Hyslop PH; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Canada; Cambridge Institute for Medical Research and Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Thornton T; Department of Medicine, University of Washington, Seattle, WA, USA., Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Vardarajan BN; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA; The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Wang LS; Arizona Alzheimer's Consortium, Phoenix, AZ, USA., Wendlund JR; PharmaTherapeutics Clinical Research, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Winslow AR; PharmaTherapeutics Clinical Research, Pfizer Worldwide Research and Development, Cambridge, MA, USA., Haines J; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA., Mayeux R; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA; The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA; The Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA; The Department of Epidemiology, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA., Schellenberg G; Arizona Alzheimer's Consortium, Phoenix, AZ, USA., Lunetta KL; Department of Biostatistics, Boston University Schools of Public Health, Boston, MA, USA., Farrer LA; Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine, Boston, MA, USA; Department of Neurology, Boston University Schools of Medicine, Boston, MA, USA; Department of Biostatistics, Boston University Schools of Public Health, Boston, MA, USA; Department of Ophthalmology, Boston University Schools of Medicine, Boston, MA, USA; Department of Epidemiology, Boston University Schools of Public Health, Boston, MA, USA. Electronic address: farrer@bu.edu.
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2017 Jul; Vol. 13 (7), pp. 727-738. Date of Electronic Publication: 2017 Feb 07.
Autor:
Marshall CR; Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Howrigan DP; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Merico D; Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Thiruvahindrapuram B; Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Wu W; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Greer DS; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Antaki D; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Shetty A; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Holmans PA; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.; National Centre for Mental Health, Cardiff University, Cardiff, UK., Pinto D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Genetics and Genomic Sciences, Seaver Autism Center, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gujral M; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Brandler WM; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Malhotra D; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA.; Neuroscience Discovery and Translational Area, Pharma Research and Early Development, F. Hoffmann-La Roche, Ltd, Basel, Switzerland., Wang Z; Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Fajarado KVF; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Maile MS; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA., Ripke S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Agartz I; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway.; Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden., Albus M; State Mental Hospital, Haar, Germany., Alexander M; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA., Amin F; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia, USA.; Department of Psychiatry and Behavioral Sciences, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA., Atkins J; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.; Hunter Medical Research Institute, New Lambton, New South Wales, Australia., Bacanu SA; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Belliveau RA Jr; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Bergen SE; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Bertalan M; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Copenhagen, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark., Bevilacqua E; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Bigdeli TB; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Black DW; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA., Bruggeman R; Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Buccola NG; School of Nursing, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA., Buckner RL; Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.; Athinoula A. Martinos Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Bulik-Sullivan B; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Byerley W; Department of Psychiatry, University of California at San Francisco, San Francisco, California, USA., Cahn W; Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands., Cai G; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Human Genetics, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Cairns MJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, New South Wales, Australia., Campion D; Centre Hospitalier du Rouvray and INSERM U1079, Faculty of Medicine, Rouen, France., Cantor RM; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA., Carr VJ; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia., Carrera N; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Catts SV; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Department of Psychiatry, Royal Brisbane and Women's Hospital, University of Queensland, Brisbane, Queensland, Australia., Chambert KD; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Cheng W; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Cloninger CR; Department of Psychiatry, Washington University, St. Louis, Missouri, USA., Cohen D; Department of Child and Adolescent Psychiatry, Assistance Publique-Hospitaux de Paris, Pierre and Marie Curie Faculty of Medicine and Institute for Intelligent Systems and Robotics, Paris, France., Cormican P; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Craddock N; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.; National Centre for Mental Health, Cardiff University, Cardiff, UK., Crespo-Facorro B; Instituto de Formación e Investigación Marqués de Valdecilla, University Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain.; Centro Investigación Biomédica en Red Salud Mental, Madrid, Spain., Crowley JJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Curtis D; Department of Psychological Medicine, Queen Mary University of London, London, UK.; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Davidson M; Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel., Davis KL; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Degenhardt F; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany., Del Favero J; Applied Molecular Genomics Unit, VIB Department of Molecular Genetics, University of Antwerp, Antwerp, Belgium., DeLisi LE; Virginia Boston Health Care System, Brockton, Massachusetts, USA.; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA., Dikeos D; First Department of Psychiatry, University of Athens Medical School, Athens, Greece., Dinan T; Department of Psychiatry, University College Cork, Cork, Ireland., Djurovic S; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Donohoe G; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.; Cognitive Genetics and Therapy Group, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland., Drapeau E; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Duan J; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA., Dudbridge F; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Eichhammer P; Department of Psychiatry, University of Regensburg, Regensburg, Germany., Eriksson J; Folkhälsan Research Center and Biomedicum Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland., Escott-Price V; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Essioux L; Translational Technologies and Bioinformatics, Pharma Research and Early Development, F. Hoffman-La Roche, Basel, Switzerland., Fanous AH; Mental Health Service Line, Washington Virginia Medical Center, Washington, DC, USA.; Department of Psychiatry, Georgetown University, Washington, DC, USA.; Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Psychiatry, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA., Farh KH; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Farrell MS; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Franke L; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Freedman R; Department of Psychiatry, University of Colorado Denver, Aurora, Colorado, USA., Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California, USA., Friedman JI; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Forstner AJ; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany., Fromer M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Genovese G; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Georgieva L; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Gershon ES; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA.; Department of Human Genetics, University of Chicago, Chicago, Illinois, USA., Giegling I; Department of Psychiatry, University of Halle, Halle, Germany.; Department of Psychiatry, University of Munich, Munich, Germany., Giusti-Rodríguez P; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Godard S; Departments of Psychiatry, and Human and Molecular Genetics, INSERM, Institut de Myologie, Hôpital de la Pitiè-Salpêtrière, Paris, France., Goldstein JI; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Gratten J; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., de Haan L; Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands., Hamshere ML; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Hansen M; Illumina, Inc., La Jolla, California, USA., Hansen T; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Copenhagen, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark., Haroutunian V; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; J.J. Peters Virginia Medical Center, Bronx, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Hartmann AM; Department of Psychiatry, University of Halle, Halle, Germany., Henskens FA; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, New South Wales, Australia.; School of Electrical Engineering and Computer Science, University of Newcastle, Newcastle, New South Wales, Australia., Herms S; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany.; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Hirschhorn JN; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA., Hoffmann P; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany.; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Hofman A; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany., Huang H; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Ikeda M; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan., Joa I; Regional Centre for Clinical Research in Psychosis, Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway., Kähler AK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kahn RS; Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands., Kalaydjieva L; Centre for Medical Research, University of Western Australia, Perth, Western Australia, Australia.; Perkins Institute for Medical Research, University of Western Australia, Perth, Western Australia, Australia., Karjalainen J; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Kavanagh D; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Keller MC; Department of Psychology, University of Colorado Boulder, Boulder, Colorado, USA., Kelly BJ; Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, New South Wales, Australia., Kennedy JL; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada., Kim Y; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Knowles JA; Department of Psychiatry, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA.; Zilkha Neurogenetics Institute, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA., Konte B; Department of Psychiatry, University of Halle, Halle, Germany., Laurent C; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.; Department of Child and Adolescent Psychiatry, Pierre and Marie Curie Faculty of Medicine, Paris, France., Lee P; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Lee SH; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Legge SE; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Lerer B; Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Levy DL; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.; Psychology Research Laboratory, McLean Hospital, Belmont, Massachusetts, USA., Liang KY; Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA., Lieberman J; Department of Psychiatry, Columbia University, New York, New York, USA., Lönnqvist J; Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland., Loughland CM; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, New South Wales, Australia., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Maher BS; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA., Maier W; Department of Psychiatry, University of Bonn, Bonn, Germany., Mallet J; CNRS, Laboratoire de Génétique Moléculaire de la Neurotransmission et des Processus Neurodégénératifs, Hôpital de la Pitié-Salpêtrière, Paris, France., Mattheisen M; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.; Department of Genomics Mathematics, University of Bonn, Bonn, Germany., Mattingsdal M; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Unit, Sørlandet Hospital, Kristiansand, Norway., McCarley RW; Virginia Boston Health Care System, Brockton, Massachusetts, USA.; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA., McDonald C; Department of Psychiatry, National University of Ireland Galway, Galway, Ireland., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Meier S; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Meijer CJ; Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands., Melle I; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Mesholam-Gately RI; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Michie PT; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; School of Psychology, University of Newcastle, Newcastle, New South Wales, Australia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milanova V; First Psychiatric Clinic, Medical University, Sofia, Bulgaria., Mokrab Y; Eli Lilly and Company, Ltd., Windlesham, UK., Morris DW; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.; Cognitive Genetics and Therapy Group, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland., Müller-Myhsok B; Max Planck Institute of Psychiatry, Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.; Cluster for Systems Neurology (SyNergy), Munich, Germany., Murphy KC; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland., Murray RM; Institute of Psychiatry, King's College London, London, UK., Myin-Germeys I; Maastricht University Medical Centre, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht, the Netherlands., Nenadic I; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany., Nertney DA; Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia., Nestadt G; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Nicodemus KK; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Nisenbaum L; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA., Nordin A; Department of Clinical Sciences, Psychiatry, Umeå University, Umeå, Sweden., O'Callaghan E; DETECT Early Intervention Service for Psychosis, Blackrock, Ireland., O'Dushlaine C; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Oh SY; Lawrence Berkeley National Laboratory, University of California at Berkeley, Berkeley, California, USA., Olincy A; Department of Psychiatry, University of Colorado Denver, Aurora, Colorado, USA., Olsen L; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Copenhagen, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark., O'Neill FA; Centre for Public Health, Institute of Clinical Sciences, Queen's University Belfast, Belfast, UK., Van Os J; Maastricht University Medical Centre, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht, the Netherlands.; Institute of Psychiatry, King's College London, London, UK., Pantelis C; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia., Papadimitriou GN; First Department of Psychiatry, University of Athens Medical School, Athens, Greece., Parkhomenko E; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Pato MT; Department of Psychiatry, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA.; Zilkha Neurogenetics Institute, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA., Paunio T; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland., Perkins DO; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Pers TH; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Denmark., Pietiläinen O; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland., Pimm J; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Pocklington AJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Powell J; Institute of Psychiatry, King's College London, London, UK., Price A; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA., Pulver AE; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Purcell SM; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Quested D; Department of Psychiatry, University of Oxford, Oxford, UK., Rasmussen HB; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Copenhagen, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark., Reichenberg A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Reimers MA; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Richards AL; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.; National Centre for Mental Health, Cardiff University, Cardiff, UK., Roffman JL; Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.; Athinoula A. Martinos Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Roussos P; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Ruderfer DM; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Sanders AR; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA., Savitz A; Neuroscience Therapeutic Area, Janssen Research and Development, Raritan, New Jersey, USA., Schall U; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, New South Wales, Australia., Schulze TG; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.; Department of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany., Schwab SG; Psychiatry and Psychotherapy Clinic, University of Erlangen, Erlangen, Germany., Scolnick EM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Scott RJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Hunter New England Health Service, Newcastle, New South Wales, Australia., Seidman LJ; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Silverman JM; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Research and Development, Bronx Veterans Affairs Medical Center, New York, New York, USA., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Söderman E; Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden., Spencer CCA; Wellcome Trust Centre for Human Genetics, Oxford, UK., Stahl EA; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Strengman E; Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, the Netherlands., Strohmaier J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Stroup TS; Department of Psychiatry, Columbia University, New York, New York, USA., Suvisaari J; Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland., Svrakic DM; Department of Psychiatry, Washington University, St. Louis, Missouri, USA., Szatkiewicz JP; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Thirumalai S; Berkshire Healthcare NHS Foundation Trust, Bracknell, UK., Tooney PA; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, New South Wales, Australia., Veijola J; Department of Psychiatry, University of Oulu, Oulu, Finland.; Department of Psychiatry, University Hospital of Oulu, Oulu, Finland., Visscher PM; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Waddington J; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Walsh D; Health Research Board, Dublin, Ireland., Webb BT; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Weiser M; Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel., Wildenauer DB; School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia., Williams NM; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Williams S; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Wolen AR; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Wormley BK; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Wray NR; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Wu JQ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.; Schizophrenia Research Institute, Sydney, New South Wales, Australia., Zai CC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Adolfsson R; Department of Clinical Sciences, Psychiatry, Umeå University, Umeå, Sweden., Andreassen OA; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Blackwood DHR; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Bramon E; Division of Psychiatry, University College London, London, UK., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Human Genetics, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Cichon S; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany.; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany., Collier DA; Eli Lilly and Company, Ltd., Windlesham, UK.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK., Corvin A; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Daly MJ; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Darvasi A; Department of Genetics, Hebrew University of Jerusalem, Jerusalem, Israel., Domenici E; Neuroscience Discovery and Translational Area, Pharma Research and Early Development, F. Hoffmann-La Roche, Ltd, Basel, Switzerland.; Centre for Integrative Biology, University of Trento, Trento, Italy., Esko T; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Gejman PV; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA., Gill M; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Gurling H; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Hultman CM; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Iwata N; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan., Jablensky AV; Schizophrenia Research Institute, Sydney, New South Wales, Australia.; Perkins Institute for Medical Research, University of Western Australia, Perth, Western Australia, Australia.; School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia.; Centre for Clinical Research in Neuropsychiatry, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia., Jönsson EG; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden., Kendler KS; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Kirov G; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Knight J; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada., Levinson DF; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA., Li QS; Neuroscience Therapeutic Area, Janssen Research and Development, Raritan, New Jersey, USA., McCarroll SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., McQuillin A; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK., Moran JL; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Mowry BJ; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Queensland, Australia., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, Bonn, Germany., Ophoff RA; Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California, USA., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.; National Centre for Mental Health, Cardiff University, Cardiff, UK., Palotie A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland., Pato CN; Department of Psychiatry, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA.; Zilkha Neurogenetics Institute, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA., Petryshen TL; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Athinoula A. Martinos Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Posthuma D; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, the Netherlands.; Department of Complex Trait Genetics, Neuroscience Campus Amsterdam, VU University Medical Center Amsterdam, Amsterdam, the Netherlands.; Department of Child and Adolescent Psychiatry, Erasmus University Medical Centre, Rotterdam, the Netherlands., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Riley BP; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA., Rujescu D; Department of Psychiatry, University of Halle, Halle, Germany.; Department of Psychiatry, University of Munich, Munich, Germany., Sklar P; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., St Clair D; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Walters JTR; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Werge T; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Copenhagen, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., O'Donovan MC; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.; National Centre for Mental Health, Cardiff University, Cardiff, UK., Scherer SW; Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics and McLaughlin Centre, University of Toronto, Toronto, Ontario, Canada., Neale BM; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Sebat J; Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, California, USA.; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, USA.
Publikováno v:
Nature genetics [Nat Genet] 2017 Jan; Vol. 49 (1), pp. 27-35. Date of Electronic Publication: 2016 Nov 21.
Autor:
Mehta D; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Tropf FC; Department of Sociology, Interuniversity Center for Social Science Theory and Methodology, University of Groningen, Groningen, the Netherlands3Department of Sociology, Nuffield College, University of Oxford, Oxford, England., Gratten J; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Bakshi A; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Zhu Z; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Bacanu SA; Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond5Department of Psychiatry, Virginia Commonwealth University, Richmond., Hemani G; Medical Research Council Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, England., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Barban N; Department of Sociology, Nuffield College, University of Oxford, Oxford, England., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Snieder H; Department of Epidemiology, University of Groningen, The University Medical Center Groningen, Groningen, the Netherlands., Mowry BJ; Queensland Brain Institute, The University of Queensland, Brisbane, Australia10Queensland Centre for Mental Health Research, Wacol, Australia., Kendler KS; Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond5Department of Psychiatry, Virginia Commonwealth University, Richmond11Department of Human and Molecular Genetics, Virginia Commonwealth University, Richm., Yang J; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Visscher PM; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., McGrath JJ; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Mills MC; Department of Sociology, Nuffield College, University of Oxford, Oxford, England., Wray NR; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Lee SH; Queensland Brain Institute, The University of Queensland, Brisbane, Australia12School of Environmental and Rural Science, University of New England, Armidale, Australia., Andreassen OA; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway14Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Bramon E; University College London, London, England., Bruggeman R; University Medical Center Groningen, Department of Psychiatry, University of Groningen, Groningen, the Netherlands., Buxbaum JD; Department of Human Genetics, Icahn School of Medicine at Mount Sinai, New York, New York18Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York19Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York., Cairns MJ; Schizophrenia Research Institute, Sydney, Australia22Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia., Cantor RM; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles., Cloninger CR; Department of Psychiatry, Washington University in St Louis, St Louis, Missouri., Cohen D; Department of Child and Adolescent Psychiatry, Assistance Publique Hôpitaux de Paris, Pierre and Marie Curie University, and Institute for Intelligent Systems and Robotics, Paris, France., Crespo-Facorro B; CIBERSAM, University Hospital Marqués de Valdecilla, University of Cantabria-IDIVAL, Department of Psychiatry, Santander, Spain28 Centro Investigación Biomédica en Red Salud Mental, Madrid, Spain., Darvasi A; Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel., DeLisi LE; Schizophrenia Research Institute, Sydney, Australia30VA Boston Health Care System, Brockton, Massachusetts., Dinan T; Department of Psychiatry, University College Cork, Cork, Ireland., Djurovic S; NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway33Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Donohoe G; Cognitive Genetics and Therapy Group, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland35Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Drapeau E; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York., Escott-Price V; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, Wales., Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles., Georgieva L; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, Wales., de Haan L; Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands., Henskens FA; Schizophrenia Research Institute, Sydney, Australia39School of Electrical Engineering and Computer Science, University of Newcastle, Newcastle, Australia40Priority Research Centre for Health Behaviour, University of Newcastle, Newcastle, Australia., Joa I; Regional Centre for Clinical Research in Psychosis, Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway., Julià A; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., Khrunin A; Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia., Lerer B; Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Limborska S; Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia., Loughland CM; Schizophrenia Research Institute, Sydney, Australia22Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia., Macek M Jr; Department of Biology and Medical Genetics, Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Marsal S; Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain., McCarley RW; VA Boston Health Care System, Brockton, Massachusetts47Department of Psychiatry, Harvard Medical School, Boston, Massachusetts., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, Scotland49Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland., McQuillin A; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, England., Melegh B; Department of Medical Genetics, University of Pécs, Pécs, Hungary52Szentagothai Research Center, University of Pécs, Pécs, Hungary., Michie PT; Schizophrenia Research Institute, Sydney, Australia53School of Psychology, University of Newcastle, Newcastle, Australia., Morris DW; Cognitive Genetics and Therapy Group, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland35Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Murphy KC; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland., Myin-Germeys I; Center for Contextual Psychiatry, Department of Neuroscience, KU Leuven, Leuven, Belgium., Olincy A; Department of Psychiatry, University of Colorado Denver, Aurora., Van Os J; Institute of Psychiatry, King's College London, London, England58Maastricht University Medical Centre, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht, the Netherlands., Pantelis C; Schizophrenia Research Institute, Sydney, Australia59Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Melbourne, Australia., Posthuma D; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, the Netherlands61Department of Complex Trait Genetics, Neuroscience Campus Amsterdam, VU University Medical Center., Quested D; Department of Psychiatry, University of Oxford, Oxford, England., Schall U; Schizophrenia Research Institute, Sydney, Australia22Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia., Scott RJ; Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia64Hunter New England Health Service, Newcastle, Australia., Seidman LJ; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts65Massachusetts Mental Health Center Public Psychiatry Division, Beth Israel Deaconess Medical Center, Boston., Toncheva D; Department of Medical Genetics, Medical University, Sofia, Bulgaria., Tooney PA; Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia67Priority Research Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle., Waddington J; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Weinberger DR; Lieber Institute for Brain Development, Baltimore, Maryland70Department of Psychiatry and Behavioral Sciences, The Johns Hopkins School of Medicine, Baltimore, Maryland71Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, Maryland72., Weiser M; Sheba Medical Center, Tel Hashomer, Israel., Wu JQ; Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.
Publikováno v:
JAMA psychiatry [JAMA Psychiatry] 2016 May 01; Vol. 73 (5), pp. 497-505.
Autor:
Beecham GW; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Dickson DW; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Scott WK; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Martin ER; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Schellenberg G; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Nuytemans K; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Larson EB; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Buxbaum JD; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Trojanowski JQ; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Van Deerlin VM; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Hurtig HI; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Mash DC; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Beach TG; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Troncoso JC; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Pletnikova O; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Frosch MP; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Ghetti B; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Foroud TM; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Honig LS; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Marder K; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Vonsattel JP; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Goldman SM; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Vinters HV; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Ross OA; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Wszolek ZK; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Wang L; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Dykxhoorn DM; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Pericak-Vance MA; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Montine TJ; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Leverenz JB; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Dawson TM; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (, Vance JM; From the John P. Hussman Institute for Human Genomics (G.W.B., W.K.S., E.R.M., K.N., L.W., D.M.D., M.A.P.-V., J.M.V.) and University of Miami Brain Endowment Bank (D.C.M.), Miller School of Medicine, University of Miami, FL; Departments of Neuroscience (D.W.D., O.A.R.) and Neurology (Z.K.W.), Mayo Clinic Florida, Jacksonville; Department of Pathology & Laboratory Medicine (G.S., J.Q.T., V.M.V.D., H.I.H.), Perelman School of Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia; Group Health Research Institute (E.B.L.), Seattle, WA; Departments of Psychiatry, and Genetics and Genomic Sciences (J.D.B.), Mount Sinai School of Medicine, New York, NY; Arizona Alzheimer's Consortium (T.G.B.), Phoenix; Sun Health Research Institute (T.G.B.), Sun City, AZ; Division of Neuropathology, Department of Pathology (J.C.T., O.P.), and Department of Neurology and the Solomon H. Snyder Department of Neuroscience (T.M.D.), Johns Hopkins University School of Medicine, Baltimore, MD; Kubik Laboratory for Neuropathology (M.P.F.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center (B.G.), and Department of Medical and Molecular Genetics (T.M.F.), Indiana University School of Medicine, Indianapolis; Departments of Neurology (L.S.H., K.M.) and Psychiatry (K.M.), Gertrude H. Sergievsky Center, and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York; Department of Pathology and Cell Biology (J.P.V.), Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, NY; The Parkinson's Institute (S.M.G.), Sunnyvale, CA; Departments of Pathology and Laboratory Medicine (Neuropathology) and Neurology (H.V.V.), David Geffen School of Medicine at University of California Los Angeles; Department of Pathology (T.J.M.), University of Washington School of Medicine, Seattle; VA Puget Sound Health Care System (
Publikováno v:
Neurology [Neurology] 2015 Mar 10; Vol. 84 (10), pp. 972-80. Date of Electronic Publication: 2015 Feb 06.
Autor:
Naj AC; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia., Jun G; Genetics Program, Department of Medicine, Boston University, Boston, Massachusetts4Department of Biostatistics, Boston University, Boston, Massachusetts5Department of Ophthalmology, Boston University, Boston, Massachusetts., Reitz C; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York7Gertrude H. Sergievsky Center, Columbia University, New York, New York8Department of Neurology, Columbia University, New York, New., Kunkle BW; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida., Perry W; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida., Park YS; The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida., Beecham GW; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida9The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida., Rajbhandary RA; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida., Hamilton-Nelson KL; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida., Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Kauwe JS; Department of Biology, Brigham Young University, Provo, Utah., Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona., Myers AJ; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida., Bird TD; Department of Neurology, University of Washington, Seattle15Geriatric Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, Minnesota., Baldwin CT; Genetics Program, Department of Medicine, Boston University, Boston, Massachusetts., Jarvik GP; Department of Genome Sciences, University of Washington, Seattle18Division of Medical Genetics, Department of Medicine, University of Washington, Seattle., Crane PK; Department of Medicine, University of Washington, Seattle., Rogaeva E; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada., Barmada MM; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania., Demirci FY; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania., Cruchaga C; Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, School of Medicine, Washington University in St Louis, St Louis, Missouri., Kramer PL; Department of Neurology, Oregon Health & Science University, Portland24Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida26Department of Neurology, Mayo Clinic, Jacksonville, Florida., Hardy J; Institute of Neurology, University College London, London, England., Graff-Radford NR; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida26Department of Neurology, Mayo Clinic, Jacksonville, Florida., Green RC; Division of Genetics, Department of Medicine, and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Larson EB; Department of Medicine, University of Washington, Seattle29Group Health Research Institute, Group Health Cooperative, Seattle, Washington., St George-Hyslop PH; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada30Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge, England., Buxbaum JD; Department of Neuroscience, Mount Sinai School of Medicine, New York, New York32Department of Psychiatry, Mount Sinai School of Medicine, New York, New York33Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York., Evans DA; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois., Schneider JA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois36Neuropathology, Department of Pathology, Rush University Medical Center, Chicago, Illinois., Lunetta KL; Department of Biostatistics, Boston University, Boston, Massachusetts., Kamboh MI; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania37Alheimer Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania., Saykin AJ; Department of Medical and Molecular Genetics, Indiana University, Indianapolis39Department of Radiology and Imaging Sciences, Indiana University, Indianapolis., Reiman EM; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona40Arizona Alzheimer's Consortium, Phoenix41Department of Psychiatry, University of Arizona, Phoenix42Banner Alzheimer's Institute, Phoenix, Arizona., De Jager PL; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology and Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts44Program in Medical and Population Genetics, Broad Ins., Bennett DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois45Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois., Morris JC; Department of Pathology and Immunology, Washington University in St Louis, St Louis, Missouri47Department of Neurology, Washington University in St Louis, St Louis, Missouri., Montine TJ; Department of Pathology, University of Washington, Seattle., Goate AM; Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, School of Medicine, Washington University in St Louis, St Louis, Missouri., Blacker D; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts50Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston., Tsuang DW; Geriatric Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington51Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Kukull WA; Department of Epidemiology, University of Washington, Seattle., Foroud TM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis., Martin ER; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida9The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida., Haines JL; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee55Vanderbilit Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee., Mayeux RP; Taub Institute on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York57Gertrude H. Sergievsky Center, Columbia University, New York, New York58Department of Neurology, Columbia University, New York, New York., Farrer LA; Genetics Program, Department of Medicine, Boston University, Boston, Massachusetts4Department of Biostatistics, Boston University, Boston, Massachusetts5Department of Ophthalmology, Boston University, Boston, Massachusetts59Department of Epidemiology, Bos., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida9The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida., Albert MS; Department of Neurology, Johns Hopkins University, Baltimore, Maryland., Albin RL; Department of Neurology, University of Michigan, Ann Arbor63Geriatric Research, Education and Clinical Center (GRECC), VA Ann Arbor Healthcare System (VAAAHS), Ann Arbor, Michigan64Michigan Alzheimer Disease Center, Ann Arbor., Apostolova LG; Department of Neurology, University of California Los Angeles, Los Angeles., Arnold SE; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia., Barber R; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth., Barnes LL; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois68Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Phoenix, Arizona., Becker JT; Departments of Psychiatry, Neurology, and Psychology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Beekly D; National Alzheimer's Coordinating Center, University of Washington, Seattle., Bigio EH; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois73Cognitive Neurology and Alzheimer's Disease Center, Northwestern University, Chicago, Illinois., Bowen JD; Swedish Medical Center, Seattle, Washington., Boxer A; Department of Neurology, University of California San Francisco, San Francisco., Burke JR; Department of Medicine, Duke University, Durham, North Carolina., Cairns NJ; Department of Pathology and Immunology, Washington University in St Louis, St Louis, Missouri., Cantwell LB; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Cao C; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa., Carlson CS; Fred Hutchinson Cancer Research Center, Seattle, Washington., Carney RM; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida., Carroll SL; Department of Pathology, University of Alabama at Birmingham, Birmingham., Chui HC; Department of Neurology, University of Southern California, Los Angeles., Clark DG; Department of Neurology, University of Alabama at Birmingham, Birmingham., Corneveaux J; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona., Cribbs DH; Department of Neurology, University of California Irvine, Irvine., Crocco EA; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida., DeCarli C; Department of Neurology, University of California Davis, Sacramento., DeKosky ST; University of Virginia School of Medicine, Charlottesville., Dick M; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida., Duara R; Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, Florida., Faber KM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis., Fallon KB; Department of Pathology, University of Alabama at Birmingham, Birmingham., Farlow MR; Department of Neurology, Indiana University, Indianapolis., Ferris S; Department of Psychiatry, New York University, New York., Frosch MP; C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown., Galasko DR; Department of Neurosciences, University of California San Diego, La Jolla., Ganguli M; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania., Gearing M; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia93Emory Alzheimer's Disease Center, Emory University, Atlanta, Georgia., Geschwind DH; Neurogenetics Program, University of California Los Angeles, Los Angeles., Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis., Gilbert JR; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida9The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida., Glass JD; Department of Neurology, Emory University, Atlanta, Georgia., Growdon JH; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston., Hamilton RL; Department of Pathology (Neuropathology), University of Pittsburgh, Pittsburgh, Pennsylvania., Harrell LE; Department of Neurology, University of Alabama at Birmingham, Birmingham., Head E; Sanders-Brown Center on Aging, Department of Molecular and Biomedical Pharmacology, University of Kentucky, Lexington., Honig LS; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York., Hulette CM; Department of Pathology, Duke University, Durham, North Carolina., Hyman BT; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston., Jicha GA; Sanders-Brown Center on Aging, Department Neurology, University of Kentucky, Lexington., Jin LW; Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento., Karydas A; Department of Neurology, University of California San Francisco, San Francisco., Kaye JA; Department of Neurology, Oregon Health & Science University, Portland103Department of Neurology, Portland Veterans Affairs Medical Center, Portland, Oregon., Kim R; Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine., Koo EH; Department of Neurosciences, University of California San Diego, La Jolla., Kowall NW; Department of Neurology, Boston University, Boston, Massachusetts105Department of Pathology, Boston University, Boston, Massachusetts., Kramer JH; Department of Neuropsychology, University of California San Francisco, San Francisco., LaFerla FM; Department of Neurobiology and Behavior, University of California Irvine, Irvine., Lah JJ; Department of Neurology, Emory University, Atlanta, Georgia., Leverenz JB; Department of Pathology, University of Washington, Seattle., Levey AI; Department of Neurology, Emory University, Atlanta, Georgia., Li G; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle., Lieberman AP; Department of Pathology, University of Michigan, Ann Arbor., Lin CF; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Lopez OL; Alheimer Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania., Lyketsos CG; Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland., Mack WJ; Department of Preventive Medicine, University of Southern California, Los Angeles., Martiniuk F; Department of Medicine - Pulmonary, New York University, New York., Mash DC; Department of Neurology, University of Miami, Miami, Florida., Masliah E; Department of Neurosciences, University of California San Diego, La Jolla113Department of Pathology, University of California San Diego, La Jolla., McCormick WC; Department of Medicine, University of Washington, Seattle., McCurry SM; School of Nursing Northwest Research Group on Aging, University of Washington, Seattle., McDavid AN; Fred Hutchinson Cancer Research Center, Seattle, Washington., McKee AC; Department of Neurology, Boston University, Boston, Massachusetts105Department of Pathology, Boston University, Boston, Massachusetts., Mesulam M; Cognitive Neurology and Alzheimer's Disease Center, Northwestern University, Chicago, Illinois115Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Miller BL; Department of Neurology, University of California San Francisco, San Francisco., Miller CA; Department of Pathology, University of Southern California, Los Angeles., Miller JW; Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento., Murrell JR; Department of Medical and Molecular Genetics, Indiana University, Indianapolis95Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis., Olichney JM; Department of Neurology, University of California Davis, Sacramento., Pankratz VS; Department of Biostatistics, Mayo Clinic, Rochester, Minnesota., Parisi JE; Department of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota119Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Paulson HL; Department of Neurology, University of Michigan, Ann Arbor., Peskind E; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, Minnesota., Pierce A; Department of Neurology, University of California Irvine, Irvine., Poon WW; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine., Potter H; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa., Quinn JF; Department of Neurology, Oregon Health & Science University, Portland., Raj A; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa., Raskind M; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle., Reisberg B; Department of Psychiatry, New York University, New York120Alzheimer's Disease Center, New York University, New York., Ringman JM; Department of Neurology, University of California Los Angeles, Los Angeles., Roberson ED; Department of Neurology, University of Alabama at Birmingham, Birmingham., Rosen HJ; Department of Neurology, University of California San Francisco, San Francisco., Rosenberg RN; Department of Neurology, University of Texas Southwestern, Dallas., Sano M; Department of Psychiatry, Mount Sinai School of Medicine, New York, New York., Schneider LS; Department of Neurology, University of Southern California, Los Angeles122Department of Psychiatry, University of Southern California, Los Angeles., Seeley WW; Department of Neurology, University of California San Francisco, San Francisco., Smith AG; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa., Sonnen JA; Department of Pathology, University of Washington, Seattle., Spina S; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis., Stern RA; Department of Neurology, Boston University, Boston, Massachusetts., Tanzi RE; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston., Thornton-Wells TA; Vanderbilit Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee., Trojanowski JQ; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Troncoso JC; Department of Pathology, Johns Hopkins University, Baltimore, Maryland., Valladares O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Van Deerlin VM; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Van Eldik LJ; Sanders-Brown Center on Aging, Department of Anatomy and Neurobiology, University of Kentucky, Lexington., Vardarajan BN; Department of Neurology, Columbia University, New York, New York., Vinters HV; Department of Neurology, University of California Los Angeles, Los Angeles125Department of Pathology & Laboratory Medicine, University of California Los Angeles, Los Angeles., Vonsattel JP; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Pathology, Columbia University, New York, New York., Weintraub S; Cognitive Neurology and Alzheimer's Disease Center, Northwestern University, Chicago, Illinois127Department of Psychiatry, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Welsh-Bohmer KA; Department of Medicine, Duke University, Durham, North Carolina128Department of Psychiatry & Behavioral Sciences, Duke University, Durham, North Carolina., Williamson J; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York., Wishnek S; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida., Woltjer RL; Department of Pathology, Oregon Health & Science University, Portland., Wright CB; Evelyn F. McKnight Brain Institute, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida., Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida., Yu CE; Department of Medicine, University of Washington, Seattle., Yu L; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.
Publikováno v:
JAMA neurology [JAMA Neurol] 2014 Nov; Vol. 71 (11), pp. 1394-404.