Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bruno H. Stricker"'
Autor:
William J. Young, Jeffrey Haessler, Jan-Walter Benjamins, Linda Repetto, Jie Yao, Aaron Isaacs, Andrew R. Harper, Julia Ramirez, Sophie Garnier, Stefan van Duijvenboden, Antoine R. Baldassari, Maria Pina Concas, ThuyVy Duong, Luisa Foco, Jonas L. Isaksen, Hao Mei, Raymond Noordam, Casia Nursyifa, Anne Richmond, Meddly L. Santolalla, Colleen M. Sitlani, Negin Soroush, Sébastien Thériault, Stella Trompet, Stefanie Aeschbacher, Fariba Ahmadizar, Alvaro Alonso, Jennifer A. Brody, Archie Campbell, Adolfo Correa, Dawood Darbar, Antonio De Luca, Jean-François Deleuze, Christina Ellervik, Christian Fuchsberger, Anuj Goel, Christopher Grace, Xiuqing Guo, Torben Hansen, Susan R. Heckbert, Rebecca D. Jackson, Jan A. Kors, Maria Fernanda Lima-Costa, Allan Linneberg, Peter W. Macfarlane, Alanna C. Morrison, Pau Navarro, David J. Porteous, Peter P. Pramstaller, Alexander P. Reiner, Lorenz Risch, Ulrich Schotten, Xia Shen, Gianfranco Sinagra, Elsayed Z. Soliman, Monika Stoll, Eduardo Tarazona-Santos, Andrew Tinker, Katerina Trajanoska, Eric Villard, Helen R. Warren, Eric A. Whitsel, Kerri L. Wiggins, Dan E. Arking, Christy L. Avery, David Conen, Giorgia Girotto, Niels Grarup, Caroline Hayward, J.Wouter Jukema, Dennis O. Mook-Kanamori, Morten Salling Olesen, Sandosh Padmanabhan, Bruce M. Psaty, Cristian Pattaro, Antonio Luiz P. Ribeiro, Jerome I. Rotter, Bruno H. Stricker, Pim van der Harst, Cornelia M. van Duijn, Niek Verweij, James G. Wilson, Michele Orini, Philippe Charron, Hugh Watkins, Charles Kooperberg, Henry J. Lin, James F. Wilson, Jørgen K. Kanters, Nona Sotoodehnia, Borbala Mifsud, Pier D. Lambiase, Larisa G. Tereshchenko, Patricia B. Munroe
Publikováno v:
Young, William J; Haessler, Jeffrey; Benjamins, Jan-Walter; Repetto, Linda; Yao, Jie; Isaacs, Aaron; Harper, Andrew R; Ramirez, Julia; Garnier, Sophie; van Duijvenboden, Stefan; Baldassari, Antoine R; Concas, Maria Pina; Duong, ThuyVy; Foco, Luisa; Isaksen, Jonas L; Mei, Hao; Noordam, Raymond; Nursyifa, Casia; Richmond, Anne; Santolalla, Meddly L; ... (2023). Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature communications, 14(1), p. 1411. Nature Publishing Group 10.1038/s41467-023-36997-w
Nature Communications, 14(1):1411. Nature Publishing Group
Nature communications, vol 14, iss 1
Young, W J, Haessler, J, Benjamins, J-W, Repetto, L, Yao, J, Isaacs, A, Harper, A R, Ramirez, J, Garnier, S, van Duijvenboden, S, Baldassari, A R, Concas, M P, Duong, T, Foco, L, Isaksen, J L, Mei, H, Noordam, R, Nursyifa, C, Richmond, A, Santolalla, M L, Sitlani, C M, Soroush, N, Thériault, S, Trompet, S, Aeschbacher, S, Ahmadizar, F, Alonso, A, Brody, J A, Campbell, A, Correa, A, Darbar, D, De Luca, A, Deleuze, J-F, Ellervik, C, Fuchsberger, C, Goel, A, Grace, C, Guo, X, Hansen, T, Heckbert, S R, Jackson, R D, Kors, J A, Lima-Costa, M F, Linneberg, A, Macfarlane, P W, Morrison, A C, Navarro, P, Porteous, D J, Pramstaller, P P, Reiner, A P, Risch, L, Schotten, U, Shen, X, Sinagra, G, Soliman, E Z, Stoll, M, Tarazona-Santos, E, Tinker, A, Trajanoska, K, Villard, E, Warren, H R, Whitsel, E A, Wiggins, K L, Arking, D E, Avery, C L, Conen, D, Girotto, G, Grarup, N, Hayward, C, Jukema, J W, Mook-Kanamori, D O, Olesen, M S, Padmanabhan, S, Psaty, B M, Pattaro, C, Ribeiro, A L P, Rotter, J I, Stricker, B H, van der Harst, P, van Duijn, C M, Verweij, N, Wilson, J G, Orini, M, Charron, P, Watkins, H, Kooperberg, C, Lin, H J, Wilson, J F, Kanters, J K, Sotoodehnia, N, Mifsud, B, Lambiase, P D, Tereshchenko, L G & Munroe, P B 2023, ' Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease ', Nature Communications, vol. 14, no. 1, 1411 . https://doi.org/10.1038/s41467-023-36997-w
Nature Communications, 14(1):1411. Nature Publishing Group
Nature communications, vol 14, iss 1
Young, W J, Haessler, J, Benjamins, J-W, Repetto, L, Yao, J, Isaacs, A, Harper, A R, Ramirez, J, Garnier, S, van Duijvenboden, S, Baldassari, A R, Concas, M P, Duong, T, Foco, L, Isaksen, J L, Mei, H, Noordam, R, Nursyifa, C, Richmond, A, Santolalla, M L, Sitlani, C M, Soroush, N, Thériault, S, Trompet, S, Aeschbacher, S, Ahmadizar, F, Alonso, A, Brody, J A, Campbell, A, Correa, A, Darbar, D, De Luca, A, Deleuze, J-F, Ellervik, C, Fuchsberger, C, Goel, A, Grace, C, Guo, X, Hansen, T, Heckbert, S R, Jackson, R D, Kors, J A, Lima-Costa, M F, Linneberg, A, Macfarlane, P W, Morrison, A C, Navarro, P, Porteous, D J, Pramstaller, P P, Reiner, A P, Risch, L, Schotten, U, Shen, X, Sinagra, G, Soliman, E Z, Stoll, M, Tarazona-Santos, E, Tinker, A, Trajanoska, K, Villard, E, Warren, H R, Whitsel, E A, Wiggins, K L, Arking, D E, Avery, C L, Conen, D, Girotto, G, Grarup, N, Hayward, C, Jukema, J W, Mook-Kanamori, D O, Olesen, M S, Padmanabhan, S, Psaty, B M, Pattaro, C, Ribeiro, A L P, Rotter, J I, Stricker, B H, van der Harst, P, van Duijn, C M, Verweij, N, Wilson, J G, Orini, M, Charron, P, Watkins, H, Kooperberg, C, Lin, H J, Wilson, J F, Kanters, J K, Sotoodehnia, N, Mifsud, B, Lambiase, P D, Tereshchenko, L G & Munroe, P B 2023, ' Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease ', Nature Communications, vol. 14, no. 1, 1411 . https://doi.org/10.1038/s41467-023-36997-w
The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but the underlying biology is unknown. Using multi-ancestry genome-wide association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b419de99c976c6e69800ab12254c1489
Autor:
Michiel L. Bots, Annette Peters, Jennifer A. Brody, Pim van der Harst, Niek Verweij, Torben Hansen, Lu-Chen Weng, Marco V Perez, Honghuang Lin, Nona Sotoodehnia, Katharina Schramm, Dennis O. Mook-Kanamori, Marcus Dörr, Susan R. Heckbert, Henry J. Lin, Jie Yao, Paul L. Huang, Melanie Waldenberger, Bruno H. Stricker, Cornelia M. van Duijn, Jelena Kornej, Kent D. Taylor, Stephan B. Felix, Julia Ramirez, Xiuqing Guo, Peter van der Meer, Patrick T. Ellinor, Emelia J. Benjamin, Amelia W. Hall, Martina Müller-Nurasyid, Steven A. Lubitz, Alexander Teumer, Ilonca Vaartjes, Niels Grarup, Kathryn L. Lunetta, Marten E. van den Berg, Aaron Isaacs, Uwe Völker, Bruce M. Psaty, Jan A. Kors, Alvaro Alonso, Seung Hoan Choi, Rudolf A. de Boer, Allan Linneberg, Sandosh Padmanabhan, Helen R. Warren, Jerome I. Rotter, Nathan A. Bihlmeyer, Man Li, Jeffrey Haessler, Charles Kooperberg, Moritz F. Sinner, Sean J. Jurgens, Folkert W. Asselbergs, Dan E. Arking, Ruifang Li-Gao, Jessica van Setten, Patricia B. Munroe, Jørgen K. Kanters, Stefan Kääb
Publikováno v:
Circulation: Genomic and Precision Medicine
Circulation. Genomic and precision medicine, vol 13, iss 5
Circulation: Genomic and Precision Medicine, 13(5):002874, 387-395. Lippincott Williams and Wilkins Ltd.
Circ. Genom. Precis. Med. 13, 387-395 (2020)
Circulation: Genomic and Precision Medicine, 13(5), 387-395. LIPPINCOTT WILLIAMS & WILKINS
Circ Genom Precis Med
Circulation-Genomic and Precision Medicine, 13(5), 387-395. Lippincott Williams & Wilkins
Circulation. Genomic and precision medicine, 13(5), 387-395. Lippincott Williams and Wilkins Ltd.
Circulation. Genomic and precision medicine, vol 13, iss 5
Circulation: Genomic and Precision Medicine, 13(5):002874, 387-395. Lippincott Williams and Wilkins Ltd.
Circ. Genom. Precis. Med. 13, 387-395 (2020)
Circulation: Genomic and Precision Medicine, 13(5), 387-395. LIPPINCOTT WILLIAMS & WILKINS
Circ Genom Precis Med
Circulation-Genomic and Precision Medicine, 13(5), 387-395. Lippincott Williams & Wilkins
Circulation. Genomic and precision medicine, 13(5), 387-395. Lippincott Williams and Wilkins Ltd.
Background: The P-wave duration (PWD) is an electrocardiographic measurement that represents cardiac conduction in the atria. Shortened or prolonged PWD is associated with atrial fibrillation (AF). We used exome-chip data to examine the associations
Autor:
Dennis O. Mook-Kanamori, Yalda Jamshidi, Peter K. Joshi, Seung Hoan Choi, Henry J. Lin, Rebecca D. Jackson, Alison D. Murray, May E. Montasser, Veikko Salomaa, Charles Kooperberg, Moritz F. Sinner, Gianfranco Sinagra, Luisa Foco, James G. Wilson, Johan Sundström, Kathleen A. Ryan, Eric A. Whitsel, Bruno H. Stricker, Sandosh Padmanabhan, Christopher Newton-Cheh, Ozren Polasek, Unnur Thorsteinsdottir, Niek Verweij, Pier D. Lambiase, Nathan R. Tucker, Stefan Kääb, Jun Ding, Stefan Weiss, Daniel F. Gudbjartsson, David Conen, Lars Lind, Ivana Kolcic, Lu-Chen Weng, J. Wouter Jukema, Kirill V. Tarasov, Xiuqing Guo, Stella Trompet, Patricia B. Munroe, Albert V. Smith, Elsayed Z. Soliman, Andrew Tinker, Antti Jula, J. Gustav Smith, Alexander P. Reiner, Sébastien Thériault, Kathryn L. Lunetta, Vilmundur Gudnason, Mika Kähönen, Massimo Mangino, Raymond Noordam, Joshua C. Bis, Alan R. Shuldiner, Tim D. Spector, Borbala Mifsud, Stefan van Duijvenboden, Jeffrey R. O'Connell, Emelia J. Benjamin, M. Benjamin Shoemaker, Stephan B. Felix, Peter W. Macfarlane, Lorenz Risch, Uwe Völker, Stephanie M. Gogarten, Maria Fernanda Lima-Costa, Julia Ramirez, Morten S. Olesen, Konstantin Strauch, Annette Peters, Aaron Isaacs, Steven A. Lubitz, Eric Boerwinkle, Carolina Roselli, James H. Cartwright, Nathalia M. Araujo, Ruth J. F. Loos, Diane Fatkin, Harry Campbell, Blair H. Smith, Thomas Meitinger, André G. Uitterlinden, Paul L. Huang, Tamara B. Harris, Kathleen F. Kerr, David J. Porteous, Martina Müller-Nurasyid, Francesco Cucca, Michiel Rienstra, Davíð O. Arnar, Amanda A. Seyerle, Caroline Hayward, M. Abdullah Said, Catriona L. K. Barnes, Kent D. Taylor, Nona Sotoodehnia, Nina Mononen, Dan M. Roden, Jonathan Marten, Terho Lehtimäki, Dan E. Arking, Anna F. Dominiczak, Jan A. Kors, Olli T. Raitakari, Igor Rudan, Yordi J. van de Vegte, Christopher P. Nelson, Erik Ingelsson, Ulrike Peters, Girish N. Nadkarni, Eduardo Tarazona-Santos, Edward G. Lakatta, Nina Hutri-Kähönen, Bruce M. Psaty, Patrick T. Ellinor, Christian Fuchsberger, Katharina Schramm, Amelia W. Hall, M. Yldau van der Ende, Alvaro Alonso, James F. Wilson, Sheila Ulivi, Rosa B. Thorolfsdottir, Stefanie Aeschbacher, Mary L. Biggs, Marten E. van den Berg, Nilesh J. Samani, Thibaud Boutin, Vilmantas Giedraitis, Honghuang Lin, Kjell Nikus, Helen R. Warren, Arie C. Maan, James J. Cranley, Adolfo Correa, Martin Gögele, Ian Ford, Katri Sääksjärvi, Georg Ehret, Michele Orini, Susan R. Heckbert, Cecilia M. Lindgren, Jie Yao, Maria Pina Concas, Pim van der Harst, Ioanna Ntalla, Jeffrey Haessler, Jerome I. Rotter, Pashupati P. Mishra, Michael J. Cutler, Erwin P. Bottinger, Cornelia M. van Duijn, Jennifer A. Brody, Paolo Gasparini, Lenore J. Launer, Andrew P. Morris, Renée de Mutsert, Aki S. Havulinna, James P. Cook, Hilma Holm, Patrick Sulem, Alessandro De Grandi, Cristian Pattaro, Gardar Sveinbjornsson, Antonio Luiz Pinho Ribeiro, Mark J. Caulfield, Gudmar Thorleifsson, Marcus Dörr, Muhammad B. Riaz, Peter P. Pramstaller, Yong Qian, Anubha Mahajan, Cathy C. Laurie, Kenneth Rice, Mark Chaffin, Kari Stefansson, Andrew A. Hicks, Solmaz Assa, Hao Mei, Leo-Pekka Lyytikäinen, Fabiola Del Greco M, Renan P. Souza, Michael Preuss, Adrienne M. Stilp, Barry London, Melanie Waldenberger, Christy L. Avery, Daniel Levy, Michael R. Barnes
Publikováno v:
Nature Communications, 11(1). Nature Publishing Group
Nature Communications, 11(1):2542. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O’Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Nature Communications, 11(1):2542. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O’Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Publisher's version (útgefin grein)
The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality. Here
The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality. Here
Autor:
Christian P. Müller, Patricia B. Munroe, Philipp S. Wild, Teresa Trenkwalder, Christian Hengstenberg, Georg Schmidt, Yalda Jamshidi, Stephan B. Felix, Renate B. Schnabel, Nilesh J. Samani, Jan A. Kors, Peter S. Braund, Bruno H. Stricker, Bernhard M. Kaess, Solmaz Assa, C. Pattaro, Uwe Völker, Matthias Nauck, M. Arfan Ikram, Thomas Münzel, Mobeen Zafar, Isabel Deisenhofer, Niek Verweij, Alexander Teumer, Alessandra Rossini, Christopher P. Nelson, Thorsten Kessler, Anna F. Dominiczak, Tim D. Spector, Harold Snieder, Marten E. van den Berg, André G. Uitterlinden, Rachel Bastiaenen, Maryam Kavousi, Christian Fuchsberger, Sandosh Padmanabhan, Claudia P. Cabrera, Leanne M. Hall, Klaus Stark, Helen R. Warren, Norbert Pfeiffer, Heribert Schunkert, Karl J. Lackner, Ilja M. Nolte, Elijah R. Behr, Marcus Dörr, Peter P. Pramstaller, Marzia De Bortoli, Martin Gögele, Pim van der Harst, Wibke Reinhard
Publikováno v:
JCI Insight, 4(23):131156. AMER SOC CLINICAL INVESTIGATION INC
JCI insight, 4(23):e131156. The American Society for Clinical Investigation
JCI insight, 4(23):e131156. The American Society for Clinical Investigation
BACKGROUND: The presence of an early repolarization pattern (ERP) on the surface ECG is associated with risk of ventricular fibrillation and sudden cardiac death. Family studies have shown that ERP is a highly heritable trait, but molecular genetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2760022c55c28cb105eb8519ce2ad42
https://research.rug.nl/en/publications/f381dbd6-a884-4b57-ad58-b6fa7d504694
https://research.rug.nl/en/publications/f381dbd6-a884-4b57-ad58-b6fa7d504694
Autor:
Barbara McKnight, Martina Müller-Nurasyid, Raha Pazoki, Michael W.T. Tanck, Thomas Engstrøm, Arthur A.M. Wilde, Man Li, Martin VanDenburgh, Marieke T. Blom, Reza Jabbari, Thomas Meitinger, Philippe Goyette, Anna Moes, Rebecca N. Mitchell, Christine M. Albert, Aravinda Chakravarti, Dan E. Arking, Jean-Claude Tardif, Rozenn N. Lemaitre, Foram N. Ashar, Pui-Yan Kwok, Frank D. Kolodgie, Jacob Tfelt-Hansen, Renu Virmani, Susan R. Heckbert, Angel C.Y. Mak, David S. Siscovick, Vinicius Tragante, Xavier Jouven, Hanno L. Tan, John D. Rioux, Mark Eijgelsheim, Ronald J. Prineas, Nona Sotoodehnia, Xiaoqing Zhao, Stefan A. Escher, Heikki V. Huikuri, Bruce M. Psaty, Charlotte Glinge, Albert Hofman, Oscar H. Franco, Florence Dumas, Bruno H. Stricker, M. Juhani Junttila, Folkert W. Asselbergs, Josef Coresh, Christopher J. O'Donnell, Paul W. Franks, Shih-Jen Hwang, Veikko Salomaa, Jan-Håkan Jansson, Stefan Kääb, Christopher Newton-Cheh, Joseph J. Maleszewski, Paul I.W. de Bakker, Jennifer A. Brody, Aki S. Havulinna, André G. Uitterlinden, Georg Ehret, Jerome I. Rotter, Thomas Lumley, Connie R. Bezzina, Marc K. Halushka, Sara L. Pulit
Publikováno v:
Ashar, F N, Mitchell, R N, Albert, C M, Newton-Cheh, C, Brody, J A, Müller-Nurasyid, M, Moes, A, Meitinger, T, Mak, A, Huikuri, H, Junttila, M J, Goyette, P, Pulit, S L, Pazoki, R, Tanck, M W, Blom, M T, Zhao, X, Havulinna, A S, Jabbari, R, Glinge, C, Tragante, V, Escher, S A, Chakravarti, A, Ehret, G, Coresh, J, Li, M, Prineas, R J, Franco, O H, Kwok, P Y, Lumley, T, Dumas, F, McKnight, B, Rotter, J I, Lemaitre, R N, Heckbert, S R, O'Donnell, C J, Hwang, S J, Tardif, J C, VanDenburgh, M, Uitterlinden, A G, Hofman, A, Stricker, B H C, De Bakker, P I W, Franks, P W, Jansson, J H, Asselbergs, F W, Halushka, M K, Maleszewski, J J, Tfelt-Hansen, J, Engstrøm, T, Salomaa, V, Virmani, R, Kolodgie, F, Wilde, A A M, Tan, H L, Bezzina, C R, Eijgelsheim, M, Rioux, J D, Jouven, X, Kääb, S, Psaty, B M, Siscovick, D S, Arking, D E & Sotoodehnia, N 2018, ' A comprehensive evaluation of the genetic architecture of sudden cardiac arrest ', European Heart Journal, vol. 39, no. 44, pp. 3961-3969 . https://doi.org/10.1093/eurheartj/ehy474
European Heart Journal
European Heart Journal, 39(44), 3961. Oxford University Press
Ashar, Foram N; Mitchell, Rebecca N; Albert, Christine M; Newton-Cheh, Christopher; Brody, Jennifer A; Müller-Nurasyid, Martina; Moes, Anna; Meitinger, Thomas; Mak, Angel; Huikuri, Heikki; Junttila, M Juhani; Goyette, Philippe; Pulit, Sara L; Pazoki, Raha; Tanck, Michael W; Blom, Marieke T; Zhao, XiaoQing; Havulinna, Aki S; Jabbari, Reza; Glinge, Charlotte; ... (2018). A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. European Heart Journal, 39(44), pp. 3961-3969. Oxford University Press 10.1093/eurheartj/ehy474
European Heart Journal, 39(44), 3961-3969. Oxford University Press
European Heart Journal, 39(44), 3961-+. Oxford University Press
European Heart Journal, Vol. 39, No 44 (2018) pp. 3961-3969
European heart journal, vol 39, iss 44
European heart journal, 39(44), 3961-3969. Oxford University Press
European Heart Journal
European Heart Journal, 39(44), 3961. Oxford University Press
Ashar, Foram N; Mitchell, Rebecca N; Albert, Christine M; Newton-Cheh, Christopher; Brody, Jennifer A; Müller-Nurasyid, Martina; Moes, Anna; Meitinger, Thomas; Mak, Angel; Huikuri, Heikki; Junttila, M Juhani; Goyette, Philippe; Pulit, Sara L; Pazoki, Raha; Tanck, Michael W; Blom, Marieke T; Zhao, XiaoQing; Havulinna, Aki S; Jabbari, Reza; Glinge, Charlotte; ... (2018). A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. European Heart Journal, 39(44), pp. 3961-3969. Oxford University Press 10.1093/eurheartj/ehy474
European Heart Journal, 39(44), 3961-3969. Oxford University Press
European Heart Journal, 39(44), 3961-+. Oxford University Press
European Heart Journal, Vol. 39, No 44 (2018) pp. 3961-3969
European heart journal, vol 39, iss 44
European heart journal, 39(44), 3961-3969. Oxford University Press
BackgroundSudden cardiac arrest (SCA) accounts for 10% of adult mortality in Western populations. While several risk factors are observationally associated with SCA, the genetic architecture of SCA in the general population remains unknown. Furthermo
Autor:
Ruth Tal-Singer, Dandi Qiao, David A. Lomas, David A. Schwartz, Robert P. Chase, Amund Gulsvik, Maxime Lamontagne, Judith M. Vonk, George T. O'Connor, Matthijs Oudkerk, Iwona Hawryłkiewicz, Per Bakke, Harry J. de Koning, Eugene R. Bleecker, Terri H. Beaty, Mi Kyeong Lee, Peter D. Paré, Nora Franceschini, Lies Lahousse, Deborah A. Meyers, Nicholas Locantore, María Soler Artigas, Xin-Qun Wang, Wim Timens, James D. Crapo, Victoria E. Jackson, Jemma B. Wilk, Jørgen Vestbo, Megan Hardin, Pawel Sliwinski, Stephen I. Rennard, Prescott G. Woodruff, Dirkje S. Postma, Peter J. Castaldi, Jae-Joon Yim, Stephen S. Rich, Guy Brusselle, Elizabeth J. Ampleford, Nick Shrine, R. Graham Barr, Harry J.M. Groen, André G. Uitterlinden, Shuguang Leng, Deog Kyeom Kim, Yohan Bossé, Steven A. Belinsky, William MacNee, Bruce M. Psaty, Stephanie J. London, Augusto A. Litonjua, Brian D. Hobbs, Traci M. Bartz, David P. Strachan, Martin D. Tobin, Woo Jin Kim, Ani Manichaikul, Ian P. Hall, Tasha E. Fingerlin, Kim de Jong, Sina A. Gharib, Louise V. Wain, John E. Hokanson, Josée Dupuis, Yohannes Tesfaigzi, Bruno H. Stricker, Edwin K. Silverman, Yeon-Mok Oh, Kari E. North, Susan R. Heckbert, Jan Willem J. Lammers, Annah B. Wyss, Jeanne C. Latourelle, David Sparrow, Michael H. Cho, Pieter Zanen, H. Marike Boezen
Publikováno v:
Nature Genetics, 49(3), 426-432. Nature Publishing Group
Nature Genetics, 49(3), 426–432. Nature Publishing Group
Nature Genetics, 49(3), 426–432. Nature Publishing Group
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide(1). We performed a genetic association study in 15,256 cases and 47,936 controls, with replication of select top results (P
Autor:
Lorenz Risch, Igor Rudan, Hilma Holm, Christopher P. Nelson, Jan A. Kors, Stefanie Aeschbacher, Stefan Kääb, Peter W. Macfarlane, Lars Lind, Amanda A. Seyerle, Ozren Polasek, Daniel F. Gudbjartsson, Xiuqing Guo, Nilesh J. Samani, Bruce M. Psaty, Rosa B. Thorolfsdottir, Elsayed Z. Soliman, Yong Qian, Mary L. Biggs, Antti Jula, Vilmundur Gudnason, Paul L. Huang, Tamara B. Harris, Gianfranco Sinagra, Luisa Foco, Anubha Mahajan, Mika Kähönen, Lu-Chen Weng, Borbala Mifsud, Stefan van Duijvenboden, Terho Lehtimäki, Jennifer A. Brody, Paolo Gasparini, Kathleen A. Ryan, Marten E. van den Berg, James J. Cranley, Eric Boerwinkle, Cathy C. Laurie, Annette Peters, Joshua C. Bis, Raymond Noordam, Andrew P. Morris, Johan Sundström, Lenore J. Launer, Stefan Weiss, Rebecca D. Jackson, Alison D. Murray, Jeffrey R. O'Connell, Aki S. Havulinna, Dennis O. Mook-Kanamori, Sheila Ulivi, Renée de Mutsert, Eric A. Whitsel, Adrienne M. Stilp, James P. Cook, Nona Sotoodehnia, Antonio Luiz Pinho Ribeiro, Seung Hoan Choi, Mark J. Caulfield, Sébastien Thériault, Henry J. Lin, Dan M. Roden, J. Wouter Jukema, James F. Wilson, Veikko Salomaa, Honghuang Lin, Andrew A. Hicks, Christy L. Avery, Nina Mononen, Dan E. Arking, Ruth J. F. Loos, Yalda Jamshidi, André G. Uitterlinden, Nina Hutri-Kähönen, Andrew Tinker, Gudmar Thorleifsson, Daniel Levy, Martina Müller-Nurasyid, Alexander P. Reiner, Bruno H. Stricker, Caroline Hayward, Yordi J. van de Vegte, Ioanna Ntalla, Tim D. Spector, Niek Verweij, Michael R. Barnes, Martin Gögele, Nathan R. Tucker, Arie C. Maan, Eduardo Tarazona-Santos, Katri Sääksjärvi, Maria Pina Concas, Pim van der Harst, Georg Ehret, Cecilia M. Lindgren, David Conen, Cornelia M. van Duijn, Muhammad B. Riaz, Leo-Pekka Lyytikäinen, Amelia W. Hall, Peter P. Pramstaller, Maria Fernanda Lima-Costa, Vilmantas Giedraitis, Emelia J. Benjamin, M. Fabiola Del Greco, Thomas Meitinger, Erwin P. Bottinger, Francesco Cucca, Aaron Isaacs, Carolina Roselli, James H. Cartwright, Massimo Mangino, Adolfo Correa, Patrick Sulem, Thibaud Boutin, Michiel Rienstra, Stephan B. Felix, Julia Ramirez, Kathleen F. Kerr, Jonathan Marten, David J. Porteous, Kent D. Taylor, Patrick T. Ellinor, Michele Orini, Susan R. Heckbert, Olli T. Raitakari, Girish N. Nadkarni, Edward G. Lakatta, Anna F. Dominiczak, Jie Yao, Erik Ingelsson, Christopher Newton-Cheh, Katharina Schramm, Jerome I. Rotter, Michael J. Cutler, Pashupati P. Mishra, Diane Fatkin, Marcus Dörr, Ulrike Peters, Solmaz Assa, Christian Fuchsberger, M. Abdullah Said, Catriona L. K. Barnes, Peter K. Joshi, M. Yldau van der Ende, Alvaro Alonso, James G. Wilson, Jun Ding, Kathryn L. Lunetta, Kjell Nikus, Helen R. Warren, Charles Kooperberg, Moritz F. Sinner, Sandosh Padmanabhan, Patricia B. Munroe, Jeffrey Haessler, Albert V. Smith, Alan R. Shuldiner, Morten S. Olesen, Konstantin Strauch, Steven A. Lubitz, J. Gustav Smith, Renan P. Souza, Michael Preuss, Kirill V. Tarasov, M. Benjamin Shoemaker, Barry London, Melanie Waldenberger, Cristian Pattaro, David O. Arnar, Gardar Sveinbjornsson, Alessandro De Grandi, Ian Ford, Kenneth Rice, Mark Chaffin, Kari Stefansson, Hao Mei, Uwe Völker, Blair H. Smith, Nathalia M. Araujo, Harry Campbell, Pier D. Lambiase, Stephanie M. Gogarten, May E. Montasser, Unnur Thorsteinsdottir, Ivana Kolcic, Stella Trompet
The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality1,2. We performed multi-ancestry (N=293,051) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3776ecad4a8ada2d09b3d886a3e960fe
https://doi.org/10.1101/712398
https://doi.org/10.1101/712398
Autor:
Jan A. Kors, Renate B. Schnabel, Rachel Bastiaenen, Philipp S. Wild, Marcus Dörr, Cristian Pattaro, Matthias Nauck, Muller Christian, Claudia P. Cabrera, Arfan Ikram, Patricia B. Munroe, Harold Snieder, Bernhard M. Kaess, Isabel Deisenhofer, Thomas Münzel, Uwe Völker, Christopher P. Nelson, Sandosh Padmanabhan, Mobeen Zafar, Ilja M. Nolte, Christian Hengstenberg, Georg Schmidt, Leanne M. Hall, Stephan B. Felix, Marten E. van den Berg, Helen R. Warren, Yalda Jamshidi, Alessandra Rossini, Anna F. Dominiczak, Martin Gögele, Klaus Stark, Christian Fuchsberger, Pim van der Harst, Wibke Reinhard, Niek Verweij, Peter P. Pramstaller, Maryam Kavousi, Peter S. Braund, Teresa Trenkwalder, Bruno H. Stricker, Thorsten Kessler, Solmaz Assa, André G. Uitterlinden, Norbert Pfeiffer, Heribert Schunkert, Alexander Teumer, Elijah R. Behr, Marzia De Bortoli, Nilesh J. Samani, Karl J. Lackner, Tim D. Spector
The presence of an early repolarization pattern (ERP) on the surface electrocardiogram (ECG) is associated with risk of ventricular fibrillation and sudden cardiac death. Family studies have shown that ERP is a highly heritable trait but molecular ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c127ee9ed9c575869a296b2af1801e
Autor:
Yalda Jamshidi, Paul I.W. de Bakker, J. Wouter Jukema, Ilaria Gandin, Monika Stoll, Christopher P. Nelson, Moritz F. Sinner, Eco J. C. de Geus, André G. Uitterlinden, Jan A. Kors, Vilmundur Gudnason, Sheila Ulivi, Jouke-Jan Hottenga, Terho Lehtimäki, Antonietta Robino, Mark Eijgelsheim, Annamaria Iorio, Niek Verweij, Martina Müller-Nurasyid, Ian Ford, Hao Mei, James G. Wilson, Albert V. Smith, Thomas Meitinger, Gianfranco Sinagra, Claudia T. Silva Aldana, Maartje N. Niemeijer, Torben Hansen, Allan Linneberg, Jennifer A. Brody, Pim van der Harst, Stella Trompet, Paolo Gasparini, Bram P. Prins, Stefan Kääb, Hamdi Mbarek, Alvaro Alonso, Leanne M. Hall, Helen R. Warren, Dan E. Arking, Peter W. Macfarlane, Annette Peters, Olli T. Raitakari, Daiane Hemerich, Mark J. Caulfield, Folkert W. Asselbergs, Dorret I. Boomsma, Aaron Isaacs, Bruno H. Stricker, Tamara B. Harris, Susan R. Heckbert, Jessica van Setten, Niels Grarup, Patricia B. Munroe, Leo-Pekka Lyytikäinen, Nilesh J. Samani, Cornelia M. van Duijn, Elsayed Z. Soliman, Nona Sotoodehnia, Jørgen K. Kanters, Melanie Waldenberger
Publikováno v:
European Journal of Human Genetics, 27(6), 952-962. Nature Publishing Group
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
European Journal of Human Genetics
van Setten, J, Verweij, N, Mbarek, H, Niemeijer, M N, Trompet, S, Arking, D E, Brody, J A, Gandin, I, Grarup, N, Hall, L M, Hemerich, D, Lyytikäinen, L-P, Mei, H, Müller-Nurasyid, M, Prins, B P, Robino, A, Smith, A V, Warren, H R, Asselbergs, F W, Boomsma, D I, Caulfield, M J, Eijgelsheim, M, Ford, I, Hansen, T, Harris, T B, Heckbert, S R, Hottenga, J-J, Iorio, A, Kors, J A, Linneberg, A, MacFarlane, P W, Meitinger, T, Nelson, C P, Raitakari, O T, Silva Aldana, C T, Sinagra, G, Sinner, M, Soliman, E Z, Stoll, M, Uitterlinden, A, van Duijn, C M, Waldenberger, M, Alonso, A, Gasparini, P, Gudnason, V, Jamshidi, Y, Kääb, S, Kanters, J K, Lehtimäki, T, Munroe, P B, Peters, A, Samani, N J, Sotoodehnia, N, Ulivi, S, Wilson, J G, de Geus, E J C, Jukema, J W, Stricker, B, van der Harst, P, de Bakker, P I W & Isaacs, A 2019, ' Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits ', European Journal of Human Genetics, vol. 27, pp. 952-962 . https://doi.org/10.1038/s41431-018-0295-z
Eur. J. Hum. Genet. 27, 952-962 (2019)
European Journal of Human Genetics, 27(6), 952-962. NATURE PUBLISHING GROUP
van Setten, J, Verweij, N, Mbarek, H, Niemeijer, M N, Trompet, S, Arking, D E, Brody, J A, Gandin, I, Grarup, N, Hall, L M, Hemerich, D, Lyytikäinen, L P, Mei, H, Müller-Nurasyid, M, Prins, B P, Robino, A, Smith, A V, Warren, H R, Asselbergs, F W, Boomsma, D I, Caulfield, M J, Eijgelsheim, M, Ford, I, Hansen, T, Harris, T B, Heckbert, S R, Hottenga, J J, Iorio, A, Kors, J A, Linneberg, A, MacFarlane, P W, Meitinger, T, Nelson, C P, Raitakari, O T, Silva Aldana, C T, Sinagra, G, Sinner, M, Soliman, E Z, Stoll, M, Uitterlinden, A, van Duijn, C M, Waldenberger, M, Alonso, A, Gasparini, P, Gudnason, V, Jamshidi, Y, Kääb, S, Kanters, J K, Lehtimäki, T, Munroe, P B, Peters, A, Samani, N J, Sotoodehnia, N, Ulivi, S, Wilson, J G, de Geus, E J C, Jukema, J W, Stricker, B, van der Harst, P, de Bakker, P I W & Isaacs, A 2019, ' Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits ', European Journal of Human Genetics, vol. 27, no. 6, pp. 952-962 . https://doi.org/10.1038/s41431-018-0295-z
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
European Journal of Human Genetics
van Setten, J, Verweij, N, Mbarek, H, Niemeijer, M N, Trompet, S, Arking, D E, Brody, J A, Gandin, I, Grarup, N, Hall, L M, Hemerich, D, Lyytikäinen, L-P, Mei, H, Müller-Nurasyid, M, Prins, B P, Robino, A, Smith, A V, Warren, H R, Asselbergs, F W, Boomsma, D I, Caulfield, M J, Eijgelsheim, M, Ford, I, Hansen, T, Harris, T B, Heckbert, S R, Hottenga, J-J, Iorio, A, Kors, J A, Linneberg, A, MacFarlane, P W, Meitinger, T, Nelson, C P, Raitakari, O T, Silva Aldana, C T, Sinagra, G, Sinner, M, Soliman, E Z, Stoll, M, Uitterlinden, A, van Duijn, C M, Waldenberger, M, Alonso, A, Gasparini, P, Gudnason, V, Jamshidi, Y, Kääb, S, Kanters, J K, Lehtimäki, T, Munroe, P B, Peters, A, Samani, N J, Sotoodehnia, N, Ulivi, S, Wilson, J G, de Geus, E J C, Jukema, J W, Stricker, B, van der Harst, P, de Bakker, P I W & Isaacs, A 2019, ' Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits ', European Journal of Human Genetics, vol. 27, pp. 952-962 . https://doi.org/10.1038/s41431-018-0295-z
Eur. J. Hum. Genet. 27, 952-962 (2019)
European Journal of Human Genetics, 27(6), 952-962. NATURE PUBLISHING GROUP
van Setten, J, Verweij, N, Mbarek, H, Niemeijer, M N, Trompet, S, Arking, D E, Brody, J A, Gandin, I, Grarup, N, Hall, L M, Hemerich, D, Lyytikäinen, L P, Mei, H, Müller-Nurasyid, M, Prins, B P, Robino, A, Smith, A V, Warren, H R, Asselbergs, F W, Boomsma, D I, Caulfield, M J, Eijgelsheim, M, Ford, I, Hansen, T, Harris, T B, Heckbert, S R, Hottenga, J J, Iorio, A, Kors, J A, Linneberg, A, MacFarlane, P W, Meitinger, T, Nelson, C P, Raitakari, O T, Silva Aldana, C T, Sinagra, G, Sinner, M, Soliman, E Z, Stoll, M, Uitterlinden, A, van Duijn, C M, Waldenberger, M, Alonso, A, Gasparini, P, Gudnason, V, Jamshidi, Y, Kääb, S, Kanters, J K, Lehtimäki, T, Munroe, P B, Peters, A, Samani, N J, Sotoodehnia, N, Ulivi, S, Wilson, J G, de Geus, E J C, Jukema, J W, Stricker, B, van der Harst, P, de Bakker, P I W & Isaacs, A 2019, ' Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits ', European Journal of Human Genetics, vol. 27, no. 6, pp. 952-962 . https://doi.org/10.1038/s41431-018-0295-z
Publisher's version (útgefin grein)
Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart
Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bec5734bbaae3105adbbaea038bf1b3
https://research.vu.nl/en/publications/28706f57-bfc4-450a-b581-9338a887dea5
https://research.vu.nl/en/publications/28706f57-bfc4-450a-b581-9338a887dea5
Autor:
Daan Loth, Fien Verhamme, Guy Brusselle, Fanfgui Sun, Josée Dupuis, Ken R. Bracke, George O'Conner, Natalie Terzikhan, Hieab H.H. Adams, Lies Lahousse, Bruno H. Stricker
Publikováno v:
Genes and environment.