Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Broome, Jai"'
Autor:
Young KL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA., Fisher V; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA., Deng X; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA., Lim E; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA., Lin BM; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA., Xu H; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA., Amin N; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam 3015CN, the Netherlands., An P; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Fohner AE; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA.; Institute for Public Health Genetics, University of Washington, Seattle, WA 98101, USA., Hidalgo B; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Lenzini P; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Kraaij R; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam 3015CN, the Netherlands., Medina-Gomez C; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam 3015CN, the Netherlands., Prokić I; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam 3015CN, the Netherlands., Rivadeneira F; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam 3015CN, the Netherlands., Sitlani C; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Tao R; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232, USA., van Rooij J; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam 3015CN, the Netherlands., Zhang D; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Broome JG; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98105, USA., Buth EJ; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Heavner BD; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Jain D; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Barnes K; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Tempus Labs, Chicago, IL 60654, USA., Boorgula MP; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Chavan S; Division of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Darbar D; Division of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA., De Andrade M; Health Quantitative Sciences Research, Mayo Clinic, Rochester, MN, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Kalyani RR; Division of Endocrinology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kardia SLR; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Kim W; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Mathias RA; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., McDonald ML; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Mitchell BD; Department of Medicine, University of Maryland, Baltimore, MD, USA., Peyser PA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Regan EA; Department of Medicine, National Jewish Health, Denver, CO, USA., Redline S; Department of Medicine, Brigham & Women's Hospital, Boston, MA, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Weiss S; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Wiggins KL; Department of Medicine, University of Washington, Seattle, WA, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Arnett D; College of Public Health, University of Kentucky, Lexington, KY, USA., Heard-Costa NL; Department of Neurology, Boston University, Boston, MA, USA., Leal S; Department of Neurology, Columbia University, New York City, NY, USA., Lin D; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA., McKnight B; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Province M; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., van Duijn CM; Nuffield Department of Population Health, St. Cross College, Oxford, UK., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA., Cupples LA; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA., Liu CT; Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA.
Publikováno v:
HGG advances [HGG Adv] 2022 Nov 25; Vol. 4 (1), pp. 100163. Date of Electronic Publication: 2022 Nov 25 (Print Publication: 2023).
Autor:
Little A, Hu Y, Sun Q, Jain D, Broome J, Chen MH, Thibord F, McHugh C, Surendran P, Blackwell TW, Brody JA, Bhan A, Chami N, de Vries PS, Ekunwe L, Heard-Costa N, Hobbs BD, Manichaikul A, Moon JY, Preuss MH, Ryan K, Wang Z, Wheeler M, Yanek LR, Abecasis GR, Almasy L, Beaty TH, Becker LC, Blangero J, Boerwinkle E, Butterworth AS, Choquet H, Correa A, Curran JE, Faraday N, Fornage M, Glahn DC, Hou L, Jorgenson E, Kooperberg C, Lewis JP, Lloyd-Jones DM, Loos RJF, Min YI, Mitchell BD, Morrison AC, Nickerson DA, North KE, O'Connell JR, Pankratz N, Psaty BM, Vasan RS, Rich SS, Rotter JI, Smith AV, Smith NL, Tang H, Tracy RP, Conomos MP, Laurie CA, Mathias RA, Li Y, Auer PL, Thornton T, Reiner AP, Johnson AD, Raffield LM
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2022 Feb 03; Vol. 31 (3), pp. 347-361.
eSCAN: scan regulatory regions for aggregate association testing using whole-genome sequencing data.
Autor:
Yang Y; Department of Statistics and Data Science, Yale University, New Haven, CT, 06511, USA., Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Huang L; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Broome JG; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.; Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA 98195, USA., Correa A; Department of Medicine and Population Health Science, University of Mississippi Medical Center, Jackson, MS, 39216, USA., Reiner A; Department of Epidemiology, University of Washington, Seattle, WA, 98195, USA.; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, 98195, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Yang Y; State Key Laboratory of Biocontrol, School of Ecology, Sun Yat-sen University, 510275 Guangzhou, China., Li Y; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Publikováno v:
Briefings in bioinformatics [Brief Bioinform] 2022 Jan 17; Vol. 23 (1).
Autor:
Hindy G; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Clinical Sciences, Lund University, Malmö, Sweden; Department of Population Medicine, Qatar University College of Medicine, QU Health, Doha, Qatar., Dornbos P; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA 02142, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA., Chaffin MD; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA., Liu DJ; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA 17033, USA., Wang M; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Selvaraj MS; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Zhang D; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Park J; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Aguilar-Salinas CA; Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico., Antonacci-Fulton L; Department of Genetics, Washington University in St. Louis, St. Louis, MO 63110, USA; The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA., Ardissino D; ASTC: Associazione per lo Studio Della Trombosi in Cardiologia, Pavia, Italy; Azienda Ospedaliero-Universitaria di Parma, Parma, Italy; Universitˆ, degli Studi di Parma, Parma, Italy., Arnett DK; Dean's Office, College of Public Health, University of Kentucky, Lexington, KY 40536, USA., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Atzmon G; Departments of Medicine and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA; University of Haifa, Faculty of Natural Science, Haifa, Israel., Ballantyne CM; Houston Methodist Debakey Heart and Vascular Center, Houston, TX 77030, USA; Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX 77030, USA., Barajas-Olmos F; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Barzilai N; Departments of Medicine and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Becker LC; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 49109, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Bottinger E; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Digital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Bown MJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Broome JG; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Burtt NP; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA 02142, USA., Cade BE; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA., Centeno-Cruz F; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Chan E; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore., Chang YC; Institute of Biomedical Sciences, Academia Sinica, Taiwan., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Cheng CY; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Choi WJ; Psomagen, Inc. (formerly Macrogen USA), 1330 Piccard Drive Ste 103, Rockville, MD 20850, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Centre for Non-Communicable Disease Research, Bangladesh., Contreras-Cubas C; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Córdova EJ; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA; NHLBI Framingham Heart Study, Framingham, MA 01702, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., DeFronzo RA; Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA., Doddapaneni H; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Duggirala R; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Dutcher SK; Department of Genetics, Washington University in St. Louis, St. Louis, MO 63110, USA; The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA., Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Emery LS; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Florez JC; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 770030, USA., Freedman BI; Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Fuster V; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain., Garay-Sevilla ME; Department of Medical Science, Division of Health Science, University of Guanajuato, Guanajuanto, Mexico., García-Ortiz H; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Germer S; New York Genome Center, New York, NY 10013, USA., Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany., Glaser B; Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Gonzalez C; Unidad de Diabetes y Riesgo Cardiovascular, Instituto Nacional de Salud Pœblica, Cuernavaca, Morelos, Mexico., Gonzalez-Villalpando ME; Centro de Estudios en Diabetes, Mexico City, Mexico., Graff M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Graham SE; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groop LC; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden; Finnish Institute for Molecular Genetics, University of Helsinki, Helsinki, Finland., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Gupta N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Han S; Division of Genome Science, Department of Precision Medicine, Chungcheongbuk-do, Republic of Korea., Hanis CL; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA; Tulane University Translational Science Institute, New Orleans, LA 70112, USA., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, MA 01702, USA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Hung YJ; Division of Endocrine and Metabolism, Tri-Service General Hospital Songshan Branch, Taipei, Taiwan., Hwang MY; Division of Genome Science, Department of Precision Medicine, Chungcheongbuk-do, Republic of Korea., Irvin MR; Department of Epidemiology, School of Public Health, UAB, Birmingham, AL 35294, USA., Islas-Andrade S; Dirección de Investigación, Hospital General de México 'Dr. Eduardo Liceaga,' Secretaría de Salud, Mexico City, Mexico., Jarvik GP; Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington Medical Center, Seattle, WA 98195, USA., Kang HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 49109, USA., Kelly T; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA., Kenny EE; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Khan AT; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Kim BJ; Division of Genome Science, Department of Precision Medicine, Chungcheongbuk-do, Republic of Korea., Kim RW; Psomagen, Inc. (formerly Macrogen USA), 1330 Piccard Drive Ste 103, Rockville, MD 20850, USA., Kim YJ; Division of Genome Science, Department of Precision Medicine, Chungcheongbuk-do, Republic of Korea., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland; University of Helsinki and Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98103, USA., Kuusisto J; Institute of Clinical Medicine, University of Eastern Finland, and Kuopio University Hospital, Kuopio, Finland., Kwak SH; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Laakso M; Institute of Clinical Medicine, University of Eastern Finland, and Kuopio University Hospital, Kuopio, Finland., Lange LA; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA., Lee J; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Lee J; Division of Genome Science, Department of Precision Medicine, Chungcheongbuk-do, Republic of Korea., Lee S; Psomagen, Inc. (formerly Macrogen USA), 1330 Piccard Drive Ste 103, Rockville, MD 20850, USA., Lehman DM; Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA., Lemaitre RN; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu J; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore., Loos RJF; Charles R. Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Lubitz SA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Lyssenko V; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden; University of Bergen, Bergen, Norway., Ma RCW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Martin LW; Division of Cardiology, Department of Medicine, George Washington University, Washington, DC 20037, USA., Martínez-Hernández A; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Mathias RA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., McGarvey ST; Department of Epidemiology and International Health Institute, Brown University School of Public Health, Providence, RI 02912, USA., McPherson R; Ruddy Canadian Cardiovascuar Genetics Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada., Meigs JB; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; General Medicine Division, Massachusetts General Hospital, Boston, MA 02114, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Meitinger T; Deutsches Forschungszentrum fŸr Herz-Kreislauferkrankungen, Partner Site Munich Heart Alliance, Munich, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany., Melander O; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden; Department of Emergency and Internal Medicine, SkŒne University Hospital, Malmö, Sweden., Mendoza-Caamal E; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Metcalf GA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Mi X; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27514, USA., Montasser ME; University of Maryland School of Medicine, Division of Endocrinology, Diabetes and Nutrition and Program for Personalized and Genomic Medicine, Baltimore, MD 21201, USA., Moon JY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Moreno-Macías H; Universidad Autónoma Metropolitana, Mexico City, Mexico., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Nelson SC; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Nilsson PM; Department of Clinical Sciences, Lund University, Malmö, Sweden., O'Connell JR; University of Maryland School of Medicine, Division of Endocrinology, Diabetes and Nutrition and Program for Personalized and Genomic Medicine, Baltimore, MD 21201, USA., Orho-Melander M; Department of Clinical Sciences, Lund University, Malmö, Sweden., Orozco L; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Park CJ; Psomagen, Inc. (formerly Macrogen USA), 1330 Piccard Drive Ste 103, Rockville, MD 20850, USA., Park KS; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peralta JM; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 49109, USA., Post WS; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA., Preuss M; Charles R. Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA; Department of Health Services, University of Washington, Seattle, WA 98101, USA., Qi Q; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63108, USA., Redline S; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA., Reiner AP; University of Washington, Seattle, WA 98101, USA., Revilla-Monsalve C; Instituto Mexicano del Seguro Social SXXI, Mexico City, Mexico., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA., Samani N; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Schunkert H; Deutsches Herzzentrum München, Technische UniversitŠt München, Deutsches Zentrum fŸr Herz-Kreislauf-Forschung, München, Germany., Schurmann C; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Digital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany; Charles R. Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Seo D; Psomagen, Inc. (formerly Macrogen USA), 1330 Piccard Drive Ste 103, Rockville, MD 20850, USA., Seo JS; Psomagen, Inc. (formerly Macrogen USA), 1330 Piccard Drive Ste 103, Rockville, MD 20850, USA., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Sladek R; Department of Human Genetics, McGill University, Montreal, QC, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, QC, Canada; McGill University and Génome Québec Innovation Centre, Montreal, QC, Canada., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., So WY; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Stilp AM; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Tai ES; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Duke-NUS Medical School Singapore, Singapore., Tam CHT; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Department of Statistics and Applied Probability, National University of Singapore, Singapore; Life Sciences Institute, National University of Singapore, Singapore., Thameem F; Department of Biochemistry, Faculty of Medicine, Health Science Center, Kuwait University, Safat, Kuwait., Tomlinson B; Faculty of Medicine, Macau University of Science & Technology, Macau, China., Tsai MY; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA., Tuomi T; Department of Endocrinology, Abdominal Centre, Helsinki University Hospital, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland., Tuomilehto J; Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Department of Public Health, University of Helsinki, Helsinki, Finland; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tusié-Luna T; Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico; Departamento de Medicina Genómica y Toxicología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/ Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Udler MS; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore; Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA., Vasan RS; NHLBI Framingham Heart Study, Framingham, MA 01702, USA; Departments of Medicine & Epidemiology, Boston University Schools of Medicine & Public Health, Boston, MA 02118, USA., Viaud Martinez KA; Illumina Laboratory Services, Illumina Inc., San Diego, CA 92122, USA., Wang FF; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Wang X; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Watkins H; Cardiovascular Medicine, Radcliffe Department of Medicine and the Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Weeks DE; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Wilson JG; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark; Steno Diabetes Center Aarhus, Aarhus, Denmark., Wong TY; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Yanek LR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Verve Therapeutics, Cambridge, MA 02139, USA., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Willer CJ; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Natarajan P; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Flannick JA; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA 02142, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA., Khera AV; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA. Electronic address: gpeloso@bu.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2022 Jan 06; Vol. 109 (1), pp. 81-96. Date of Electronic Publication: 2021 Dec 20.
Autor:
Hu Y; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98105, USA., Stilp AM; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., McHugh CP; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Rao S; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Broad Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA., Jain D; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Zheng X; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Lane J; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA., Méric de Bellefon S; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Chen MH; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Wheeler M; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA., Yao Y; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Broad Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA., Ren C; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Broad Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA., Broome J; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Moon JY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Hobbs BD; Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge CB1 8RN, UK; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98105, USA., Blackwell TW; TOPMed Informatics Research Center, University of Michigan, Department of Biostatistics, Ann Arbor, MI 48109, USA., Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94601, USA., Ryan K; Department of Medicine, Division of Endocrinology, Diabetes & Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Duggirala R; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA., Heard-Costa N; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Min N; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Ekunwe L; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT 05405, USA., Faraday N; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA., Almasy L; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia and Department of Genetics University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Kundu K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton CB10 1SA, UK; Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK., Smith AV; TOPMed Informatics Research Center, University of Michigan, Department of Biostatistics, Ann Arbor, MI 48109, USA., Gabriel S; Broad Institute, Boston, MA 02142, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Fornage M; University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Lloyd-Jones DM; Northwestern University, Chicago, IL 60208, USA., Vasan RS; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Departments of Cardiology and Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Smith NL; Department of Epidemiology, University of Washington, Seattle, WA 98105, USA; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98105, USA; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA 98105, USA., North KE; Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Becker LC; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Lewis JP; Department of Medicine, Division of Endocrinology, Diabetes & Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Abecasis GR; TOPMed Informatics Research Center, University of Michigan, Department of Biostatistics, Ann Arbor, MI 48109, USA., Hou L; Northwestern University, Chicago, IL 60208, USA., O'Connell JR; Department of Medicine, Division of Endocrinology, Diabetes & Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Beaty TH; School of Public Health, John Hopkins University, Baltimore, MD 21205, USA., Kaplan R; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA., Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94601, USA., Psaty BM; Department of Epidemiology, University of Washington, Seattle, WA 98105, USA; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA 98105, USA; Department of Medicine, University of Washington, Seattle, WA 98105, USA., Kooperberg C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98105, USA., Walton RT; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Kleinstiver BP; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA., Tang H; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Soranzo N; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Department of Human Genetics, Wellcome Sanger Institute, Hinxton CB10 1SA, UK; Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge CB1 8RN, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge CB1 8RN, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge CB1 8RN, UK; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge CB1 8RN, UK., Nickerson D; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Mitchell BD; Department of Medicine, Division of Endocrinology, Diabetes & Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Johnson AD; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53205, USA., Li Y; Departments of Biostatistics, Genetics, Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Mathias RA; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MA 21205, USA., Lettre G; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada; Faculté de Médecine, Université de Montréal, Montréal, QC H1T 1C8, Canada., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA., Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Laurie CA; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Bauer DE; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Broad Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA., Conomos MP; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA 98105, USA. Electronic address: apreiner@uw.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2021 May 06; Vol. 108 (5), pp. 874-893. Date of Electronic Publication: 2021 Apr 21.
Autor:
Mikhaylova, Anna V, McHugh, Caitlin P, Polfus, Linda M, Raffield, Laura M, Boorgula, Meher Preethi, Blackwell, Thomas W, Brody, Jennifer A, Broome, Jai, Chami, Nathalie, Chen, Ming-Huei, Conomos, Matthew P, Cox, Corey, Curran, Joanne E, Daya, Michelle, Ekunwe, Lynette, Glahn, David C, Heard-Costa, Nancy, Highland, Heather M, Hobbs, Brian D, Ilboudo, Yann, Jain, Deepti, Lange, Leslie A, Miller-Fleming, Tyne W, Min, Nancy, Moon, Jee-Young, Preuss, Michael H, Rosen, Jonathon, Ryan, Kathleen, Smith, Albert V, Sun, Quan, Surendran, Praveen, de Vries, Paul S, Walter, Klaudia, Wang, Zhe, Wheeler, Marsha, Yanek, Lisa R, Zhong, Xue, Abecasis, Goncalo R, Almasy, Laura, Barnes, Kathleen C, Beaty, Terri H, Becker, Lewis C, Blangero, John, Boerwinkle, Eric, Butterworth, Adam S, Chavan, Sameer, Cho, Michael H, Choquet, Hélène, Correa, Adolfo, Cox, Nancy, DeMeo, Dawn L, Faraday, Nauder, Fornage, Myriam, Gerszten, Robert E, Hou, Lifang, Johnson, Andrew D, Jorgenson, Eric, Kaplan, Robert, Kooperberg, Charles, Kundu, Kousik, Laurie, Cecelia A, Lettre, Guillaume, Lewis, Joshua P, Li, Bingshan, Li, Yun, Lloyd-Jones, Donald M, Loos, Ruth JF, Manichaikul, Ani, Meyers, Deborah A, Mitchell, Braxton D, Morrison, Alanna C, Ngo, Debby, Nickerson, Deborah A, Nongmaithem, Suraj, North, Kari E, O'Connell, Jeffrey R, Ortega, Victor E, Pankratz, Nathan, Perry, James A, Psaty, Bruce M, Rich, Stephen S, Soranzo, Nicole, Rotter, Jerome I, Silverman, Edwin K, Smith, Nicholas L, Tang, Hua, Tracy, Russell P, Thornton, Timothy A, Vasan, Ramachandran S, Zein, Joe, Mathias, Rasika A, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Reiner, Alexander P, Auer, Paul L
Publikováno v:
American journal of human genetics, vol 108, iss 10
Many common and rare variants associated with hematologic traits have been discovered through imputation on large-scale reference panels. However, the majority of genome-wide association studies (GWASs) have been conducted in Europeans, and determini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::1f3a94426432e7d8d437082d4c6c39d7
https://escholarship.org/uc/item/6432c6xx
https://escholarship.org/uc/item/6432c6xx
Autor:
Hu, Yao, Stilp, Adrienne M, McHugh, Caitlin P, Rao, Shuquan, Jain, Deepti, Zheng, Xiuwen, Lane, John, Méric de Bellefon, Sébastian, Raffield, Laura M, Chen, Ming-Huei, Yanek, Lisa R, Wheeler, Marsha, Yao, Yao, Ren, Chunyan, Broome, Jai, Moon, Jee-Young, de Vries, Paul S, Hobbs, Brian D, Sun, Quan, Surendran, Praveen, Brody, Jennifer A, Blackwell, Thomas W, Choquet, Hélène, Ryan, Kathleen, Duggirala, Ravindranath, Heard-Costa, Nancy, Wang, Zhe, Chami, Nathalie, Preuss, Michael H, Min, Nancy, Ekunwe, Lynette, Lange, Leslie A, Cushman, Mary, Faraday, Nauder, Curran, Joanne E, Almasy, Laura, Kundu, Kousik, Smith, Albert V, Gabriel, Stacey, Rotter, Jerome I, Fornage, Myriam, Lloyd-Jones, Donald M, Vasan, Ramachandran S, Smith, Nicholas L, North, Kari E, Boerwinkle, Eric, Becker, Lewis C, Lewis, Joshua P, Abecasis, Goncalo R, Hou, Lifang, O'Connell, Jeffrey R, Morrison, Alanna C, Beaty, Terri H, Kaplan, Robert, Correa, Adolfo, Blangero, John, Jorgenson, Eric, Psaty, Bruce M, Kooperberg, Charles, Walton, Russell T, Kleinstiver, Benjamin P, Tang, Hua, Loos, Ruth JF, Soranzo, Nicole, Butterworth, Adam S, Nickerson, Debbie, Rich, Stephen S, Mitchell, Braxton D, Johnson, Andrew D, Auer, Paul L, Li, Yun, Mathias, Rasika A, Lettre, Guillaume, Pankratz, Nathan, Laurie, Cathy C, Laurie, Cecelia A, Bauer, Daniel E, Conomos, Matthew P, Reiner, Alexander P, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Publikováno v:
American journal of human genetics, vol 108, iss 5
Whole-genome sequencing (WGS), a powerful tool for detecting novel coding and non-coding disease-causing variants, has largely been applied to clinical diagnosis of inherited disorders. Here we leveraged WGS data in up to 62,653 ethnically diverse pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::445eb02b1c412ec0c77798d591b7420a
https://escholarship.org/uc/item/24j6v92r
https://escholarship.org/uc/item/24j6v92r
Autor:
Li, Xihao, Li, Zilin, Zhou, Hufeng, Gaynor, Sheila M, Liu, Yaowu, Chen, Han, Sun, Ryan, Dey, Rounak, Arnett, Donna K, Aslibekyan, Stella, Ballantyne, Christie M, Bielak, Lawrence F, Blangero, John, Boerwinkle, Eric, Bowden, Donald W, Broome, Jai G, Conomos, Matthew P, Correa, Adolfo, Cupples, L Adrienne, Curran, Joanne E, Freedman, Barry I, Guo, Xiuqing, Hindy, George, Irvin, Marguerite R, Kardia, Sharon LR, Kathiresan, Sekar, Khan, Alyna T, Kooperberg, Charles L, Laurie, Cathy C, Liu, X Shirley, Mahaney, Michael C, Manichaikul, Ani W, Martin, Lisa W, Mathias, Rasika A, McGarvey, Stephen T, Mitchell, Braxton D, Montasser, May E, Moore, Jill E, Morrison, Alanna C, O'Connell, Jeffrey R, Palmer, Nicholette D, Pampana, Akhil, Peralta, Juan M, Peyser, Patricia A, Psaty, Bruce M, Redline, Susan, Rice, Kenneth M, Rich, Stephen S, Smith, Jennifer A, Tiwari, Hemant K, Tsai, Michael Y, Vasan, Ramachandran S, Wang, Fei Fei, Weeks, Daniel E, Weng, Zhiping, Wilson, James G, Yanek, Lisa R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group, Neale, Benjamin M, Sunyaev, Shamil R, Abecasis, Gonçalo R, Rotter, Jerome I, Willer, Cristen J, Peloso, Gina M, Natarajan, Pradeep, Lin, Xihong
Publikováno v:
Nature genetics, vol 52, iss 9
Large-scale whole-genome sequencing studies have enabled the analysis of rare variants (RVs) associated with complex phenotypes. Commonly used RV association tests have limited scope to leverage variant functions. We propose STAAR (variant-set test f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e52aef530ecaa2ce04de16503b6abfa5
https://escholarship.org/uc/item/61s9b995
https://escholarship.org/uc/item/61s9b995
Autor:
Little, Amarise, Hu, Yao, Sun, Quan, Jain, Deepti, Broome, Jai, Chen, Ming-Huei, Thibord, Florian, McHugh, Caitlin, Surendran, Praveen, Blackwell, Thomas W, Brody, Jennifer A, Bhan, Arunoday, Chami, Nathalie, De Vries, Paul S, Ekunwe, Lynette, Heard-Costa, Nancy, Hobbs, Brian D, Manichaikul, Ani, Moon, Jee-Young, Preuss, Michael H, Ryan, Kathleen, Wang, Zhe, Wheeler, Marsha, Yanek, Lisa R, Abecasis, Goncalo R, Almasy, Laura, Beaty, Terri H, Becker, Lewis C, Blangero, John, Boerwinkle, Eric, Butterworth, Adam S, Choquet, Hélène, Correa, Adolfo, Curran, Joanne E, Faraday, Nauder, Fornage, Myriam, Glahn, David C, Hou, Lifang, Jorgenson, Eric, Kooperberg, Charles, Lewis, Joshua P, Lloyd-Jones, Donald M, Loos, Ruth JF, Min, Yuan-I, Mitchell, Braxton D, Morrison, Alanna C, Nickerson, Deborah A, North, Kari E, O'Connell, Jeffrey R, Pankratz, Nathan, Psaty, Bruce M, Vasan, Ramachandran S, Rich, Stephen S, Rotter, Jerome I, Smith, Albert V, Smith, Nicholas L, Tang, Hua, Tracy, Russell P, Conomos, Matthew P, Laurie, Cecelia A, Mathias, Rasika A, Li, Yun, Auer, Paul L, NHLBI Trans-Omics For Precision Medicine (TOPMed) Consortium, Thornton, Timothy, Reiner, Alexander P, Johnson, Andrew D, Raffield, Laura M
Platelets play a key role in thrombosis and hemostasis. Platelet count (PLT) and mean platelet volume (MPV) are highly heritable quantitative traits, with hundreds of genetic signals previously identified, mostly in European ancestry populations. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff676eac561a92af83d0cf59fcce5f46