Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yik Ying Teo"'
Autor:
Maude E. Phipps, Boon Peng Hoh, Yan Lu, Thuhairah Hasrah Abdul Rahman, Yushimah Yunus, Rick Twee-Hee Ong, Farhang Aghakhanian, Chee Wei Yew, Xiaoji Wang, Yik Ying Teo, Mohammad Zahirul Hoque, Christopher Lok Yung Voo, Jong Bhak, Dongsheng Lu, Shuhua Xu, Lai-Ping Wong, Lian Deng, Subbiah Vijay Kumar, Siti Shuhada Mokhtar
Publikováno v:
Human Genetics. 137:161-173
Southeast Asia (SEA) is enriched with a complex history of peopling. Malaysia, which is located at the crossroads of SEA, has been recognized as one of the hubs for early human migration. To unravel the genomic complexity of the native inhabitants of
Autor:
Jin Zhou, Yik Ying Teo
Publikováno v:
European Journal of Human Genetics. 24:1195-1201
Investigating how an ancestral population diverges to give rise to distinct subpopulations remains a fundamental pursuit in population genetics. There is broad consensus for the ‘Out-of-Africa' hypothesis that states that modern humans arose ∼200
Publikováno v:
European Journal of Human Genetics. 20:1300-1307
Genome-wide association studies have seen unprecedented success in identifying genetic loci that correlate with disease susceptibility and severity. Early phases of these studies have predominantly been performed in the Caucasian populations. The nex
Autor:
Yik-Ying Teo, Jia Nee Foo, Kee Seng Chia, Xuanyao Liu, Nisha Esakimuthu Pillai, Anthony Youzhi Cheng, Linda Wei-Lin Tan, Wenting Xu, Rick Twee-Hee Ong, Seok-Hwee Koo, Peter Little, Richie Soong, Peng Chen, Markus R. Wenk, Jason Kuan Han Lai, Lai-Ping Wong, Chiea Chuen Khor, Wei-Yen Lim, Woei-Yuh Saw
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004377 (2014)
PLoS Genetics
PLoS Genetics
South Asia possesses a significant amount of genetic diversity due to considerable intergroup differences in culture and language. There have been numerous reports on the genetic structure of Asian Indians, although these have mostly relied on genoty
Publikováno v:
Bioinformatics (Oxford, England). 30(12)
Motivation: Whole-genome sequencing (WGS) is now routinely used for the detection and identification of genetic variants, particularly single nucleotide polymorphisms (SNPs) in humans, and this has provided valuable new insights into human diversity,
Publikováno v:
Nature reviews. Genetics. 11(2)
Medical research in Africa has yet to benefit from the advent of genome-wide association (GWA) analysis, partly because the genotyping tools and statistical methods that have been developed for European and Asian populations struggle to deal with the
Autor:
Rick Twee-Hee Ong, Kee Seng Chia, Edmund J.D. Lee, Jieming Chen, Yik Ying Teo, Mark Seielstad, Adrian Tan, Kerrin S. Small, Chee-Seng Ku, Erwin Tantoso, Xueling Sim
Publikováno v:
Genome research. 19(11)
The Singapore Genome Variation Project (SGVP) provides a publicly available resource of 1.6 million single nucleotide polymorphisms (SNPs) genotyped in 268 individuals from the Chinese, Malay, and Indian population groups in Southeast Asia. This onli
Autor:
Julie Makani, Kathryn Fitzpatrick, Ogobara K. Duombo, Jennifer Evans, Claire Potter, Giorgio Sirugo, Enmoore Lin, Christina Hubbart, Abier Elzein, Martha M. Lemnge, Anthony Enimil, Alioune Ly, Olukemi K. Amodu, Valentina D. Mangano, Angie Green, Alphaxard Manjurano, Dominic P. Kwiatkowski, Ivo Mueller, David Barnwell, Anna E. Jeffreys, Marryat Stevens, Thomas N. Williams, David Modiano, Sarah J. Dunstan, Taane G. Clark, Susana Campino, Tobias O. Apinjoh, Tran Tinh Hien, Sodiomon B. Sirima, David J. Conway, Terrie Taylor, Anavaj Sakuntabhai, L. Amenga-Etego, Catherine L. Moyes, Nguyen Ngoc Quyen, Laurens Manning, Mahamadou Diakite, Katharine Cook, Patrick H. Corran, Jeremy Farrar, Nadira D. Karunaweera, Kevin Marsh, Ogobara K. Doumbo, Catherine Hughes, Eric A. Achidi, Kirk A. Rockett, Chris Drakeley, Tsiri Agbenyega, Panos Deloukas, Mahamadou A. Thera, Kalifa Bojang, Julie Evans, Aaron Vanderwal, Christopher V. Plowe, Pascal Michon, Adama Tall, Aceme Nyika, Michael Gottlieb, Renee Watson, Gilbert Kokwaro, Jiannis Ragoussis, Eleanor M. Riley, Stephen Allen, Katja Kivinen, Muntaser E. Ibrahim, Bronwyn MacInnis, Vysaul Nyirongo, Elilan Somaskantharajah, Ayman S. Hussein, Alan Doyle, Carolyne M. Ndila, Michael T. Wilson, Muminatou Jallow, Jane Rogers, Abdoulaye Djimde, Deepika Fernando, Jantina DeVries, Patrick E. Duffy, Odile Puijalon, Yik Ying Teo, Kate Rowlands, Michael W. Parker, Deus S. Ishengoma, Marilyn McCreight, Edith C. Bougouma, Tom Oluoch, Rebecca Wrigley, Kerrin S. Small, Hugh Reyburn, Gareth Maslen, Malcolm E. Molyneux, Sarah Auburn, Eliza Hilton, Lee Hart, Pratap Singhasivanon, Alieu Mendy, Miguel A. Sanjoaquin, Magnus Manske, Anita Ghansah, Rajika L. Dewasurendra, Amagana Dolo, Dan Carucci, Theonest K. Mutabingwa, Prapat Suriyaphol, Marita Troye-Blomberg, Paul Risley, Susan Bull, Rolf D. Horstmann, Daniel Alcock, Ousman Toure, Kojo Koram, John C. Reeder, Norbert Peshu
Publikováno v:
Nature. 456(7223)
Large-scale studies of genomic variation could assist efforts to eliminate malaria. But there are scientific, ethical and practical challenges to carrying out such studies in developing countries, where the burden of disease is greatest. The Malaria
Autor:
Rick Twee-Hee Ong, Erwin Tantoso, Yik Ying Teo, Peter Little, Lai-Ping Wong, Bowen Li, Woei-Yuh Saw, Wenting Xu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e106681 (2014)
PLoS ONE, Vol 9, Iss 9, p e106681 (2014)
Next-generation genotyping microarrays have been designed with insights from large-scale sequencing of exomes and whole genomes. The exome genotyping arrays promise to query the functional regions of the human genome at a fraction of the sequencing c