Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yun-Hsuan Chang"'
Autor:
Yun-Hsuan Chang, Tzu-Yun Wang, Sheng-Yu Lee, Shiou-Lan Chen, Chih-Chun Huang, Po See Chen, Yen Kuang Yang, Jau-Shyong Hong, Ru-Band Lu
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Studies suggest that a functional polymorphism of brain-derived neurotrophic factor (BDNF), polymorphism BDNF Val66Met affects cognitive functions, however, the effect is unclear in bipolar II (BD-II) disorder. We used the Wechsler Memory Scale-third
Externí odkaz:
https://doaj.org/article/06327c1a0f62493ea4cbc9a0e7b39f97
Autor:
Shih Heng Chen, Kao Chin Chen, Chia Ling Li, Nian-Sheng Tzeng, Yun Hsuan Chang, Po See Chen, Tsai Hsin Hsieh, Yen Kuang Yang, San Yuan Huang, Chun Hsien Chu, Sheng Yu Lee, Tzu Yun Wang, I. Hui Lee, Shiou Lan Chen, Yi Lun Chung, Jau-Shyong Hong, Ru Band Lu, Liang-Jen Wang
Publikováno v:
European Addiction Research. 22:201-209
Background: Different drug dependencies may have unique genetic vulnerabilities. Changes in serotonin availability and function have been linked to addiction. We investigated whether 2 serotonergic polymorphisms, TPH1 A218C (rs1800532) and 5-HTT-link
Autor:
Kao Chin Chen, Hui Chen Ko, Po See Chen, Yen Kuang Yang, Yun Hsuan Chang, I. Hui Lee, Sheng Yu Lee, Shiou Lan Chen, Ru Band Lu, Nian-Sheng Tzeng, Tzu Yun Wang, San Yuan Huang
Publikováno v:
Bipolar Disorders. 17:536-542
Objectives A high prevalence rate of bipolar disorder (BP) comorbid with alcohol dependence (AD) (BP+AD) in Western patients with BP has been reported, but whether this is true for Han Chinese with BP is uncertain. We explored the prevalence of BP+AD
Autor:
Yu Shan Wang, Yun Hsuan Chang, Po See Chen, Tzu Yun Wang, Yen Kuang Yang, San Yuan Huang, Shih-Hsien Lin, Chen-Lin Wang, Ru Band Lu, Sheng Yu Lee, Shiou Lan Chen, I-Hui Lee
Publikováno v:
European Psychiatry. 29:142-148
The presence of comorbid anxiety disorders (AD) and bipolar II disorders (BP-II) compounds disability complicates treatment, worsens prognosis, and has been understudied. The genes involved in metabolizing dopamine and encoding dopamine receptors, su
Autor:
Shih Heng Chen, I. Hui Lee, Chen-Lin Wang, Yen Kuang Yang, Sheng Yu Lee, Chun Hsien Chu, Shiou Lan Chen, Tzung Lieh Yeh, Yun Hsuan Chang, Tzu Yun Wang, Ru Band Lu, San Yuan Huang, Nian-Sheng Tzeng, Pin-Hsi Yeh
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 43:134-139
Understanding the influences of genes involved in dopamine and serotonin metabolism, such as the aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) genes, is critical for understanding addictive behavior. In addition, dopamine D2 r
Autor:
Ru Band Lu, Shih Heng Chen, Tzung Lieh Yeh, Yun Hsuan Chang, I. Hui Lee, Sheng Yu Lee, Shiou Lan Chen, Yen Kuang Yang, San Yuan Huang, Shih-Hsien Lin, Po-Hsiu Kuo, Chun Hsien Chu, Nian-Sheng Tzeng
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 39:382-387
Objectives Bipolar disorder is a severe mental disorder with prominent genetic etiologic factors. Dopaminergic dysfunction has been implicated in the pathogenesis of bipolar disorder, which suggests that the dopamine D3 receptor gene (DRD3) is a stro
Autor:
Nian-Sheng Tzeng, Ru Band Lu, I. Hui Lee, Tzung Lieh Yeh, Yun Hsuan Chang, Chun Hsieh Chu, Shih Hsien Lin, Sheng Yu Lee, Shiou Lan Chen, San Yuan Huang, Yen Kuang Yang, Chen Lin Wang
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 38:247-251
Objective Clarifying the similarities and differences between the two most common subtypes of bipolar disorder, bipolar-I and bipolar-II, is essential for improving our understanding of them. Because the serotonergic system has been implicated in the
Autor:
Nian-Sheng Tzeng, Sheng Yu Lee, Shiou Lan Chen, Chen-Lin Wang, Shih Heng Chen, Yen Kuang Yang, Tzung Lieh Yeh, Ru Band Lu, Yun Hsuan Chang, I. Hui Lee, San Yuan Huang
Publikováno v:
The World Journal of Biological Psychiatry. 12:385-391
Objectives. Clarifying the association between bipolar I and bipolar II disorders at the genetic level is essential for improving our understanding of them. In this study, we evaluated the hypothesis that the dopaminergic polymorphisms are risk facto
Autor:
Yun Hsuan Chang, Yen Kuang Yang, Ru Band Lu, Nian-Sheng Tzeng, San Yuan Huang, Po See Chen, Tzu Yun Wang, Sheng Yu Lee, Shiou Lan Chen, I. Hui Lee, Kao Chin Chen, Liang-Jen Wang
Publikováno v:
Scientific Reports
Bipolar II disorder (BP-II), characterized by recurrent dysregulation of mood, is a serious and chronic psychiatric illness. However, BP-II is commonly under-recognized, even in psychiatric settings. Because dopaminergic disturbance is thought to be
Autor:
Po See Chen, Tzu Yun Wang, Shih Heng Chen, Yun Hsuan Chang, Yen Kuang Yang, Ru Band Lu, Chun Hsien Chu, Jau-Shyong Hong, Sheng Yu Lee, Shiou Lan Chen
Publikováno v:
Scientific Reports
BDNF and its gene polymorphism may be important in synaptic plasticity and neuron survival, and may become a key target in the physiopathology of long-term heroin use. Thus, we investigated the relationships between brain-derived neurotrophic factor