Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Samir H. Barghout"'
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms. 1865(6)
Histone lysine methylation is a post-translational modification that plays a key role in the epigenetic regulation of a broad spectrum of biological processes. Moreover, the dysregulation of histone lysine methyltransferases (KMTs) has been implicate
Publikováno v:
The FASEB Journal. 36
Autor:
Mark D. Minden, Neil MacLean, Steven M. Chan, Sanduni Liyanagae, Sara Mirali, Changjiang Xu, James R. Hawley, Samir H. Barghout, Rashim Pal Singh, Elias Orouji, Aaron D. Schimmer, Xiaoming Wang, Gary D. Bader, Marcela Gronda, Dilshad H. Khan, Joelle Soriano, Mathieu Lupien, Veronique Voisin, Yulia Jitkova, Danny V. Jeyaraju, Geethu E. Thomas, David Sharon, Adina Borenstein, Rose Hurren, Ayesh K. Seneviratene, Andrea Arruda
Publikováno v:
Cell Stem Cell. 26:926-937.e10
Leukemic stem cells (LSCs) rely on oxidative metabolism and are differentially sensitive to targeting mitochondrial pathways, which spares normal hematopoietic cells. A subset of mitochondrial proteins is folded in the intermembrane space via the mit