Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Ross, L"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 6, p e1010792 (2023)
Experimental models that capture the genetic complexity of human disease and allow mechanistic explorations of the underlying cell, tissue, and organ interactions are crucial to furthering our understanding of disease biology. Such models require com
Externí odkaz:
https://doaj.org/article/343a5a5b8eaf49e7909fd1976bc95854
Autor:
Erdem Bangi, Peter Smibert, Andrew V. Uzilov, Alexander G. Teague, Sindhura Gopinath, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Huan Wang, Jorge Gomez, John Mascarenhas, Aye S. Moe, Chun Yee Lau, Patricia Taik, Chetanya Pandya, Max Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Celina Ang, Eric E. Schadt, Marshall R. Posner, Ross L. Cagan
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102212- (2021)
Summary: Adenoid cystic carcinoma (ACC) is a rare cancer type that originates in the salivary glands. Tumors commonly invade along nerve tracks in the head and neck, making surgery challenging. Follow-up treatments for recurrence or metastasis includ
Externí odkaz:
https://doaj.org/article/a515dc8776494774a7791cde6351eadf
Autor:
Hui Yu, Jolena N. Waddell, Shihuan Kuang, Ross L. Tellam, Noelle E. Cockett, Christopher A. Bidwell
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background In food animal agriculture, there is a need to identify the mechanisms that can improve the efficiency of muscle growth and protein accretion. Callipyge sheep provide excellent machinery since the up-regulation of DLK1 and RTL1 re
Externí odkaz:
https://doaj.org/article/07d437829e0c443e9bab6730fc9bde7a
Autor:
Jacob L. Glass, Xiaowen Chen, Ari Melnick, Sheng Li, Ruud Delwel, Alan H. Shih, Ross L. Levine, Christopher E. Mason, Cem Meydan, Jiahui Wang
Publikováno v:
Cancer Discovery, 10(12), 1934-1949. American Association for Cancer Research Inc.
Cancer Discov
Cancer Discov
Epigenetic allele diversity is linked to inferior prognosis in acute myeloid leukemia (AML). However, the source of epiallele heterogeneity in AML is unknown. Herein we analyzed epiallele diversity in a genetically and clinically annotated AML cohort
Autor:
Martin Carroll, Ahmet Zehir, Sombeet Sahu, Isabelle S. Csete, Benjamin Demaree, Cyrille L. Delley, Aaron D. Viny, Minal Patel, Christopher Famulare, Chrysanthi Ainali, Manimozhi Manivannan, Raajit K. Rampal, Tiffany R. Merlinsky, Michael Bowman, Aaron D Goldberg, Adam R. Abate, Kelly L. Bolton, Sara E. Meyer, Robert L. Bowman, Pedro Mendez, Linde A. Miles, Aik Ooi, Robert Durruthy-Durruthy, Ross L. Levine
Publikováno v:
Nature
Nature, vol 587, iss 7834
Nature, vol 587, iss 7834
Myeloid malignancies, including acute myeloid leukaemia (AML), arise from the expansion of haematopoietic stem and progenitor cells that acquire somatic mutations. Bulk molecular profiling has suggested that mutations are acquired in a stepwise fashi
Autor:
Akkari, Yassmine M.N., Baughn, Linda B., Dubuc, Adrian M., Smith, Adam C., Mallo, Maria del Mar, Dal Cin, Paola, Diez-Campelo, María, Gallego, Marta S., Granada, Isabel, Haase, Detlef, Schlegelberger, Brigitte, Slavutsky, Irma, Mecucci, Cristina, Levine, Ross L., Hasserjian, Robert P., Sole, F, Levy, Brynn, Xu, Xinjie, Universitat Autònoma de Barcelona
Publikováno v:
Blood
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cytogenetics has long represented a critical component in the clinical evaluation of hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot of genome-wide copy number and structural variation, which have been shown to dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e901253cf997a9e551592c3964fcbacf
https://ddd.uab.cat/record/270547
https://ddd.uab.cat/record/270547
Autor:
Yu Tian, Andre E Kim, Stephanie A Bien, Yi Lin, Conghui Qu, Tabitha A Harrison, Robert Carreras-Torres, Virginia Díez-Obrero, Niki Dimou, David A Drew, Akihisa Hidaka, Jeroen R Huyghe, Kristina M Jordahl, John Morrison, Neil Murphy, Mireia Obón-Santacana, Cornelia M Ulrich, Jennifer Ose, Anita R Peoples, Edward A Ruiz-Narvaez, Anna Shcherbina, Mariana C Stern, Yu-Ru Su, Franzel J B van Duijnhoven, Volker Arndt, James W Baurley, Sonja I Berndt, D Timothy Bishop, Hermann Brenner, Daniel D Buchanan, Andrew T Chan, Jane C Figueiredo, Steven Gallinger, Stephen B Gruber, Sophia Harlid, Michael Hoffmeister, Mark A Jenkins, Amit D Joshi, Temitope O Keku, Susanna C Larsson, Loic Le Marchand, Li Li, Graham G Giles, Roger L Milne, Hongmei Nan, Rami Nassir, Shuji Ogino, Arif Budiarto, Elizabeth A Platz, John D Potter, Ross L Prentice, Gad Rennert, Lori C Sakoda, Robert E Schoen, Martha L Slattery, Stephen N Thibodeau, Bethany Van Guelpen, Kala Visvanathan, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Peter T Campbell, Graham Casey, David V Conti, Marc J Gunter, Anshul Kundaje, Juan Pablo Lewinger, Victor Moreno, Polly A Newcomb, Bens Pardamean, Duncan C Thomas, Konstantinos K Tsilidis, Ulrike Peters, W James Gauderman, Li Hsu, Jenny Chang-Claude
Publikováno v:
Journal of the National Cancer Institute, 114(8), 1135-1148
Journal of the National Cancer Institute 114 (2022) 8
Journal of the National Cancer Institute, vol 114, iss 8
J Natl Cancer Inst
Journal of the National Cancer Institute 114 (2022) 8
Journal of the National Cancer Institute, vol 114, iss 8
J Natl Cancer Inst
Background The use of menopausal hormone therapy (MHT) may interact with genetic variants to influence colorectal cancer (CRC) risk. Methods We conducted a genome-wide, gene-environment interaction between single nucleotide polymorphisms and the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea807defd956eee15cae187a8555db7
https://research.wur.nl/en/publications/genome-wide-interaction-analysis-of-genetic-variants-with-menopau
https://research.wur.nl/en/publications/genome-wide-interaction-analysis-of-genetic-variants-with-menopau
Autor:
Rebeca Santano, Rocío Rubio, Berta Grau-Pujol, Valdemiro Escola, Osvaldo Muchisse, Inocência Cuamba, Marta Vidal, Pau Cisteró, Gemma Ruiz-Olalla, Ruth Aguilar, Maria Demontis, Jose Carlos Jamine, Anélsio Cossa, Charfudin Sacoor, Jorge Cano, Luis Izquierdo, Chetan E. Chitnis, Ross L. Coppel, Virander Chauhan, David Cavanagh, Sheetij Dutta, Evelina Angov, Deepak Gaur, Lisette van Lieshout, Bin Zhan, Jose Muñoz, Gemma Moncunill, Carlota Dobaño
Publikováno v:
Santano, R, Rubio, R, Grau-Pujol, B, Escola, V, Muchisse, O, Cuamba, I, Vidal, M, Cisteró, P, Ruiz-Olalla, G, Aguilar, R, Demontis, M, Jamine, J C, Cossa, A, Sacoor, C, Cano, J, Izquierdo, L, Chitnis, C E, Coppel, R L, Chauhan, V, Cavanagh, D, Dutta, S, Angov, E, Gaur, D, van Lieshout, L, Zhan, B, Muñoz, J, Moncunill, G & Dobaño, C 2021, ' Plasmodium falciparum and helminth coinfections Increase IgE and parasite-specific IgG responses ', Microbiology Spectrum, vol. 9, no. 3, e01109 . https://doi.org/10.1128/SPECTRUM.01109-21
Microbiology Spectrum, Vol 9, Iss 3 (2021)
MICROBIOLOGY SPECTRUM, 9(3). AMER SOC MICROBIOLOGY
Microbiology Spectrum
Microbiology Spectrum, Vol 9, Iss 3 (2021)
MICROBIOLOGY SPECTRUM, 9(3). AMER SOC MICROBIOLOGY
Microbiology Spectrum
Coinfection with Plasmodium falciparum and helminths may impact the immune response to these parasites because they induce different immune profiles. We studied the effects of coinfections on the antibody profile in a cohort of 715 Mozambican childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677587385f273fe8089c010256bb341f
https://hdl.handle.net/1887/3277787
https://hdl.handle.net/1887/3277787
Autor:
Eneda Toska, Emiliano Cocco, Jane Park, Jorge S. Reis-Filho, Ross L. Levine, Pier Selenica, Jordan E. Otto, Maurizio Scaltriti, Fan Wu, Clayton K. Collings, Lorenzo Ferrando, Komal Jhaveri, Carmen Chan, Erik Ladewig, Huiyong Zhao, José Baselga, Yanyan Cai, Sagar Chhangawala, Mirna Sallaku, Cristian Serna-Tamayo, Pedram Razavi, Richard Koche, Andrew R. D’Avino, Christina S. Leslie, Guotai Xu, Alison Zhao, Arnaud Da Cruz Paula, Yuanming Cheng, Cigall Kadoch, Xuan Qu, Matthew Witkin
Publikováno v:
Nat Genet
Mutations in ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, are the most common alterations of the SWI/SNF complex in estrogen-receptor-positive (ER(+)) breast cancer. We identify that ARID1A inactivating mutations are present at a hi
Autor:
Ana Peixoto, Ian Tomlinson, Thérèse Truong, Amanda E. Toland, Anna Marie Mulligan, Michael Untch, Susan J. Ramus, Kenneth Offit, John J. Spinelli, Clarice R. Weinberg, Kyriaki Michailidou, Javier Benitez, Rita K. Schmutzler, Lizet E. van der Kolk, Heli Nevanlinna, Annika Lindblom, Sara Margolin, Stella Koutros, Elza Khusnutdinova, Diana Eccles, Lenka Foretova, Wolfgang Janni, Jennifer T. Loud, Roger L. Milne, Patrick Neven, Thomas U. Ahearn, Hedy S. Rennert, Karolina Prajzendanc, Melissa C. Southey, Ramunas Janavicius, Finn Cilius Nielsen, Pascal Guénel, Antoinette Hollestelle, Jolanta Lissowska, Ni Zhao, Melissa Christiaens, Hoda Anton-Culver, Ans M.W. van den Ouweland, Christopher A. Haiman, Debra Frost, Vessela N. Kristensen, Bernard Peissel, Muhammad Usman Rashid, Noura Mebirouk, Claudine Isaacs, Matthias W. Beckmann, Sofia Khan, Xia Jiang, Jack A. Taylor, Peter Hillemanns, Robert Winqvist, Susan L. Neuhausen, Marina Bermisheva, Alicja Wolk, Katherine L. Nathanson, Judy Garber, Siranoush Manoukian, Simon S. Cross, Flavio Lejbkowicz, Manjeet K. Bolla, Goska Leslie, Saundra S. Buys, Banu Arun, Xiaohong R. Yang, Peter Schürmann, Irene Konstantopoulou, Mia M. Gaudet, Rob A. E. M. Tollenaar, Joe Dennis, Louise Izatt, David E. Goldgar, Anna Jakubowska, Alicja Lukomska, Fabienne Lesueur, Susanna C. Larsson, Peter Devilee, Helen Byers, Bernd Holleczek, Marc Tischkowitz, Arif B. Ekici, Austin Miller, Carl Blomqvist, Christopher R. Hake, Paul D.P. Pharoah, Harvey A. Risch, Kristin K. Zorn, Mehdi Manoochehri, Kamila Czene, Peter A. Fasching, Trinidad Caldés, Hanna Huebner, Agnes Jager, William G. Newman, Lesley McGuffog, Maren T. Scheuner, Nick Orr, Susan M. Domchek, Antonis C. Antoniou, Peter Kraft, Pooja Middha Kapoor, Daniel R. Barnes, Christine L. Clarke, Douglas F. Easton, Bernadette A M Heemskerk-Gerritsen, Ross L. Prentice, Mark E. Sherman, Elizabeth J. van Rensburg, Michael Jones, Åke Borg, Diether Lambrechts, Mark H. Greene, Mark S. Goldberg, Peter J. Hulick, Maria Elena Martinez, Arto Mannermaa, Frans B. L. Hogervorst, Christian F. Singer, Johanna Rantala, Esther M. John, Jesse Nodora, Wendy K. Chung, Csilla Szabo, Mads Thomassen, Tracy A. O'Mara, Kelly-Anne Phillips, Manuela Gago-Dominguez, Jacques Simard, John L. Hopper, Jacopo Azzollini, Rudolf Kaaks, Haoyu Zhang, Eitan Friedman, Heiko Becher, János Papp, Thomas Rüdiger, Alison M. Dunning, Daniele Campa, Alfons Meindl, Lothar Häberle, Ana Blanco, Eric Hahnen, Barbara Wappenschmidt, Elaine F. Harkness, Audrey Y. Jung, Guanghao Qi, Zumuruda Abu Ful, Maria A. Caligo, Priyanka Sharma, Håkan Olsson, Elke M van Veen, Marion Piedmonte, Linetta B. Koppert, Usha Menon, Laura Matricardi, Jonine D. Figueroa, Wei Zheng, Milena Jakimovska, Katarzyna Białkowska, Renske Keeman, Matti A. Rookus, William J. Tapper, J. Peto, Paul L. Auer, Andreas Schneeweiss, Xiao-Ou Shu, Miriam Dwek, Elvira Mingazheva, Hermann Brenner, Emilija Lazarova, Atocha Romero, Rulla M. Tamimi, Laura Papi, Hans Wildiers, Catriona McLean, Montserrat Garcia-Closas, Matthias Rübner, Thomas Brüning, Graham G. Giles, Robert J. MacInnis, Hans Christiansen, Sten Cornelissen, Paul A. James, Georgia Chenevix-Trench, Tjoung-Won Park-Simon, Nilanjan Chatterjee, D. Gareth Evans, Ignacio Briceño, Mary B. Daly, Annegien Broeks, Evgeny N. Imyanitov, Jonathan Beesley, Snezhana Smichkoska, Thilo Dörk, Yon-Dschun Ko, Paolo Peterlongo, Celine M. Vachon, Claire Mulot, Kristiina Aittomäki, Liene Nikitina-Zake, Manuel R. Teixeira, Edith Olah, Florentia Fostira, Beth N. Peshkin, Pierre Laurent-Puig, M. B. Terry, Michael T. Parsons, Anna González-Neira, Julie Lecarpentier, Jacek Gronwald, Fergus J. Couch, Mariarosaria Calvello, Leigha Senter, Ute Hamann, Brigitte Rack, Marco Montagna, Simon A. Gayther, Barbara Burwinkel, Anne-Vibeke Lænkholm, Irene L. Andrulis, Sabine Behrens, Beth Y. Karlan, Anthony J. Swerdlow, Marjanka K. Schmidt, Cari M. Kitahara, Emmanouil Saloustros, Dijana Plaseska-Karanfilska, Melissa A. Troester, Diana Torres, Daniel Barrowdale, Elinor J. Sawyer, Hiltrud Brauch, Minouk J. Schoemaker, Dale P. Sandler, José A. García-Sáenz, Jennifer Stone, Qin Wang, Conxi Lázaro, Paolo Radice, Jan Lubinski, Jose E. Castelao, Natalia Bogdanova, Drakoulis Yannoukakos, Davide Bondavalli, Kristan J. Aronson, Gad Rennert, Wing-Yee Lo, Robert N. Hoover, Dominique Stoppa-Lyonnet, Nadine Tung, Stephen J. Chanock, Andrew K. Godwin, Angela Cox, Maartje J. Hooning, Anthony Howell, Volker Arndt, Penny Soucy, Jenny Chang-Claude, Kathleen Claes, Olufunmilayo I. Olopade, Jeffrey N. Weitzel, Stig E. Bojesen, Sara Y Brucker, Darcy L. Thull, Darya Prokofyeva, Taru A. Muranen, Ben Schöttker, Orland Diez, Susan M. Gapstur, Sarah Sampson, Bernardo Bonanni, Per Hall, Ana Vega
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Genetics, 52(6), 572-581. Nature Publishing Group
Nature Genetics, 52(6), 572-581. NATURE RESEARCH
Zhang, H, Ahearn, T U, Lecarpentier, J, Barnes, D, Beesley, J, Qi, G, Jiang, X, O’Mara, T A, Zhao, N, Bolla, M K, Dunning, A M, Dennis, J, Wang, Q, Ful, Z A, Aittomäki, K, Andrulis, I L, Anton-Culver, H, Arndt, V, Aronson, K J, Arun, B K, Auer, P L, Azzollini, J, Barrowdale, D, Becher, H, Beckmann, M W, Behrens, S, Benitez, J, Bermisheva, M, Bialkowska, K, Blanco, A, Blomqvist, C, Bogdanova, N V, Bojesen, S E, Bonanni, B, Bondavalli, D, Borg, A, Brauch, H, Brenner, H, Briceno, I, Broeks, A, Brucker, S Y, Brüning, T, Burwinkel, B, Buys, S S, Byers, H, Caldés, T, Caligo, M A, Christiansen, H, Laenkholm, A V, Nielsen, F C, Thomassen, M, kConFab Investigators, ABCTB Investigators, EMBRACE Study & GEMO Study Collaborators 2020, ' Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses ', Nature Genetics, vol. 52, no. 6, pp. 572-581 . https://doi.org/10.1038/s41588-020-0609-2
2020, ' Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses ', Nature Genetics . https://doi.org/10.1038/s41588-020-0609-2
Nature Genetics
Universidad de Barcelona
Nature Genetics, 52(6), 572-581. Nature Publishing Group
Nature Genetics, 52(6), 572-581. NATURE RESEARCH
Zhang, H, Ahearn, T U, Lecarpentier, J, Barnes, D, Beesley, J, Qi, G, Jiang, X, O’Mara, T A, Zhao, N, Bolla, M K, Dunning, A M, Dennis, J, Wang, Q, Ful, Z A, Aittomäki, K, Andrulis, I L, Anton-Culver, H, Arndt, V, Aronson, K J, Arun, B K, Auer, P L, Azzollini, J, Barrowdale, D, Becher, H, Beckmann, M W, Behrens, S, Benitez, J, Bermisheva, M, Bialkowska, K, Blanco, A, Blomqvist, C, Bogdanova, N V, Bojesen, S E, Bonanni, B, Bondavalli, D, Borg, A, Brauch, H, Brenner, H, Briceno, I, Broeks, A, Brucker, S Y, Brüning, T, Burwinkel, B, Buys, S S, Byers, H, Caldés, T, Caligo, M A, Christiansen, H, Laenkholm, A V, Nielsen, F C, Thomassen, M, kConFab Investigators, ABCTB Investigators, EMBRACE Study & GEMO Study Collaborators 2020, ' Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses ', Nature Genetics, vol. 52, no. 6, pp. 572-581 . https://doi.org/10.1038/s41588-020-0609-2
2020, ' Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses ', Nature Genetics . https://doi.org/10.1038/s41588-020-0609-2
Nature Genetics
Genome-wide analysis identifies 32 loci associated with breast cancer susceptibility, accounting for estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 status and tumor grade. Breast cancer susceptibility variants f